The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
From in vitro to in vivo Models of Bacterial Biofilm-Related Infections
Open accessAbstract
The influence of microorganisms growing as sessile communities in a large number of human infections has been extensively studied and recognized for 30–40 years, therefore warranting intense scientific and medical research. Nonetheless, mimicking the biofilm-life style of bacteria and biofilm-related infections has been an arduous task. Models used to study biofilms range from simple in vitro to complex in vivo models of tissues or device-related infections. These different models have progressively contributed to the current knowledge of biofilm physiology within the host context. While far from a complete understanding of the multiple elements controlling the dynamic interactions between the host and biofilms, we are nowadays witnessing the emergence of promising preventive or curative strategies to fight biofilm-related infections. This review undertakes a comprehensive analysis of the literature from a historic perspective commenting on the contribution of the different models and discussing future venues and new approaches that can be merged with more traditional techniques in order to model biofilm-infections and efficiently fight them.
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Metadata
- Authors
- Lebeaux, D., Chauhan, A., Rendueles, O., & Beloin, C.
- Venue
- Pathogens
- Publisher
- MDPI AG
- Published
- 2013-05-13
- Volume
- 2
- Issue
- 2
- Pages
- 288-356
- ISSN
- 2076-0817 (ISSN-L)
- OpenAlex
- W2036596008
- Cited by
- 545
- References
- 26
- FWCI
- 10.49
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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