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Exploring the Therapeutic Potential of Medicinal Plants in the Context of Gastrointestinal Health: A Review

Julián-Flores, Antonio, Aguilar-Zárate, Pedro, Michel, Mariela R., Sepúlveda-Torre, Leonardo, Torres-León, Cristian, Aguilar, Cristóbal N., Chávez-González, Mónica L.·2025·Plants
DOI 10.3390/plants14050642
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Abstract

Medicinal plants represent promising sources for the treatment of gastrointestinal disorders because of their abundance in bioactive compounds with therapeutic properties. Throughout history, various plant species have been used to alleviate digestive ailments, and studies have revealed the presence of metabolites with anti-inflammatory, antibacterial, antiviral, antiparasitic, antidiarrheal, antioxidant, and anticancer activities. The secondary metabolites responsible for these properties include alkaloids, terpenoids, and phenolic compounds, with the latter, particularly flavonoids, being the most associated with their bioactivities. Gastrointestinal diseases, such as gastritis, peptic ulcers, gastroesophageal reflux disease, inflammatory bowel disease, irritable bowel syndrome, and gastrointestinal cancer, are caused primarily by bacteria, parasites, viruses, and the consumption of raw or undercooked foods. These conditions significantly impact human health, necessitating the development of safer and more effective therapeutic alternatives. After an extensive literature review, several plant species with widespread use in the treatment of these disorders were identified, including Matricaria chamomilla, Mentha spicata, Melissa officinalis, Artemisia ludoviciana, Flourensia cernua, Phoradendron californicum, and Turnera difusa. This study revealed that the analyzed plants are rich in bioactive compounds, which confer their medicinal properties. However, many other plants commonly used to treat digestive disorders have been scarcely studied, highlighting the need for further research.

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Cited by

Metadata

Authors
Julián-Flores, A., Aguilar-Zárate, P., Michel, M. R., Sepúlveda-Torre, L., Torres-León, C., Aguilar, C. N., & Chávez-González, M. L.
Venue
Plants
Publisher
MDPI AG
Published
2025-02-20
Volume
14
Issue
5
Pages
642
ISSN
2223-7747
DOI
10.3390/plants14050642
Cited by
17
References
8
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
Tecnológico Nacional de México (20024.24-P)

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Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.