The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation
Open accessAbstract
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world is still expanding. Thus, there is an urgent need to better understand this novel virus and find a way to control its spread. Like other coronaviruses, the nucleocapsid (N) protein is one of the most crucial structural components of SARS-CoV-2. This protein shares 90% homology with the severe acute respiratory syndrome coronavirus N protein, implying functional significance. Based on the evolutionary conservation of the N protein in coronavirus, we reviewed the currently available knowledge regarding the SARS-CoV-2 N protein in terms of structure, biological functions, and clinical application as a drug target or vaccine candidate.
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Cites
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Cited by
Structural biology of SARS-CoV-2: open the door for novel therapies
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The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base
Huuskonen, S., Liu, X., Pöhner, I., Redchuk, T., Salokas, K., Lundberg, R., Maljanen, S., Belik, M., Reinholm, A., Kolehmainen, P., et al. (2024) · Cell Discovery · doi:10.1038/s41421-024-00748-y · Cited by 12
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“This strongly suggests that a co-operative activity exists in haplotype-mediated protein communication, which was already made explicit in previously described haplotype-delimited protein interaction networks [14].”
Background
Metadata
- Authors
- Bai, Z., Cao, Y., Liu, W., & Li, J.
- Venue
- Viruses
- Publisher
- MDPI AG
- Published
- 2021-06-10
- Volume
- 13
- Issue
- 6
- Pages
- 1115
- ISSN
- 1999-4915 (ISSN-L)
- OpenAlex
- W3168384292
- Cited by
- 348
- References
- 78
- FWCI
- 19.47
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bai, Z., Cao, Y., Liu, W., & Li, J. (2021). The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation. Viruses. https://doi.org/10.3390/v13061115
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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