Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer

PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer

Hartkopf, A. D., Taran, F., Wallwiener, M., Walter, C. B., Krämer, B., Grischke, E., & Brucker, S. Y. (2016) · Breast Care · doi:10.1159/000453569 · Cited by 30,989

Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review

Wanchoo, R., Karam, S., Uppal, N. N., Barta, V. S., Deray, G., Devoe, C., Launay‐Vacher, V., Jhaveri, K. D., & on behalf of Cancer and Kidney International Network Workgroup on Immune Checkpoint Inhibitors (2017) · American Journal of Nephrology · doi:10.1159/000455014 · Cited by 15,320

The blockade of immune checkpoints in cancer immunotherapy

Pardoll, D. M. (2012) · Nature Reviews Cancer · doi:10.1038/nrc3239 · Cited by 13,838

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Tumeh, P. C., Harview, C. L., Yearley, J. H., Shintaku, I. P., Taylor, E. J. M., Robert, L., Chmielowski, B., Spasic, M., Henry, G., Ciobanu, V., et al. (2014) · Nature · doi:10.1038/nature13954 · Cited by 6,609

Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion

Schreiber, R. D., Old, L. J., & Smyth, M. J. (2011) · Science · doi:10.1126/science.1203486 · Cited by 6,474

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

Herbst, R. S., Soria, J.-C., Kowanetz, M., Fine, G. D., Hamid, O., Gordon, M. S., Sosman, J. A., McDermott, D. F., Powderly, J. D., Gettinger, S. N., et al. (2014) · Nature · doi:10.1038/nature14011 · Cited by 5,231

The immune contexture in human tumours: impact on clinical outcome

Fridman, W. H., Pagès, F., Sautès-Fridman, C., & Galon, J. (2012) · Nature reviews. Cancer · doi:10.1038/nrc3245 · Cited by 4,981

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

Snyder, A., Makarov, V., Merghoub, T., Yuan, J., Zaretsky, J. M., Desrichard, A., Walsh, L. A., Postow, M. A., Wong, P., Ho, T. S., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1406498 · Cited by 4,286

Nivolumab plus Ipilimumab in Advanced Melanoma

Wolchok, J. D., Kluger, H., Callahan, M. K., Postow, M. A., Rizvi, N. A., Lesokhin, A. M., Segal, N. H., Ariyan, C. E., Gordon, R.-A., Reed, K., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1302369 · Cited by 4,230

Molecular and genetic properties of tumors associated with local immune cytolytic activity

Rooney, M. S., Shukla, S. A., Wu, C. J., Getz, G., & Hacohen, N. (2015) · Cell · doi:10.1016/j.cell.2014.12.033 · Cited by 3,825

Accuracy and Clinical Relevance of Intra-Tumoral Fusobacterium nucleatum Detection in Formalin-Fixed Paraffin-Embedded (FFPE) Tissue by Droplet Digital PCR (ddPCR) in Colorectal Cancer

Datorre, J. G., de Carvalho, A. C., dos Reis, M. B., dos Reis, M., Matsushita, M., Santos, F. A., Guimarães, D. P., & Reis, R. M. (2022) · Diagnostics · doi:10.3390/diagnostics12010114 · Cited by 15

Bacteria-Mediated Oncogenesis and the Underlying Molecular Intricacies: What We Know So Far

Prasad, S. K., Bhat, S., Shashank, D., Akshatha, C. R., Sindhu, R., Rachtanapun, P., Devegowda, D., Santhekadur, P. K., & Sommano, S. R. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.836004 · Cited by 15

Deep learning enabled integration of tumor microenvironment microbial profiles and host gene expressions for interpretable survival subtyping in diverse types of cancers

Zhang, H., Xiong, X., Cheng, M., Ji, L., & Ning, K. (2024) · mSystems · doi:10.1128/msystems.01395-24 · Cited by 18

Our Microbiome: On the Challenges, Promises, and Hype

Federici, S., Suez, J., & Elinav, E. (2020) · Results and problems in cell differentiation · doi:10.1007/978-3-030-51849-3_20 · Cited by 15

Low Abundance Fusobacterium Nucleatum Supports Early Pregnancy Development – An In Vitro Study

Heusler, M., Einenkel, R., Ehrhardt, J., Muzzio, D. O., & Zygmunt, M. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.698045 · Cited by 14

Importance of Zinc Nanoparticles for the Intestinal Microbiome of Weaned Piglets

Baholet, D., Skalíčková, S., Bátik, A., Malyugina, S., Skládanka, J., & Horký, P. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.852085 · Cited by 15

Tryptophan metabolism and piglet diarrhea: Where we stand and the challenges ahead

Zhao, X., Pang, J., Zhang, W., Peng, X., Yang, Z., Bai, G., & Xia, Y. (2024) · Animal nutrition · doi:10.1016/j.aninu.2024.03.005 · Cited by 14

L‑fucose ameliorates the carcinogenic properties of Fusobacterium nucleatum in colorectal cancer

Duan, C., Tang, X., Wang, W., Qian, W., Fu, X., Deng, X., Han, C., & Hou, X. (2020) · Oncology Letters · doi:10.3892/ol.2020.12404 · Cited by 14

Prognostic Value of Fusobacterium nucleatum after Abdominoperineal Resection for Anal Squamous Cell Carcinoma

Hilmi, M., Neuzillet, C., Lefèvre, J. H., Svrcek, M., Vacher, S., Benhaïm, L., Dartigues, P., Samalin, E., Lazartigues, J., Emile, J., et al. (2022) · Cancers · doi:10.3390/cancers14071606 · Cited by 14

Both endogenous and exogenous miR-139–5p inhibit Fusobacterium nucleatum-related colorectal cancer development

Zhao, Y., Tao, Q., Li, S., Zheng, P., Liu, J., & Liang, X. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173459 · Cited by 14

Detection of Fusobacterium nucleatum in Patients with Colitis-Associated Colorectal Cancer

Dregelies, T., Haumaier, F., Sterlacci, W., Backert, S., & Vieth, M. W. (2023) · Current Microbiology · doi:10.1007/s00284-023-03398-7 · Cited by 13

Fusobacteriumnucleatum: Pathophysiological and Clinical Involvement in Inflammatory Bowel Diseases, Colorectal Cancer and Cardiovascular Diseases

Quagliariello, V., Forte, P., Ciappina, G., Colarusso, L., Giorgi, C., Fiorica, F., Bottari, A., Mauro, G. D., Maurea, N., & Berretta, M. (2025) · Cancers · doi:10.3390/cancers17203348 · Cited by 12

The gut microbiome in colorectal cancer: mechanisms of carcinogenesis and emerging microbiota-targeted therapies

Li, Y., Shen, X., Wang, D., & Sun, K. (2026) · Discover Oncology · doi:10.1007/s12672-025-04367-1 · Cited by 14

Fusobacterium nucleatum load in MSI colorectal cancer subtypes

Ono, T., Yamaguchi, T., Takao, M., Kojika, E., Iijima, T., & Horiguchi, S. (2022) · International Journal of Clinical Oncology · doi:10.1007/s10147-022-02218-5 · Cited by 13

Clinicopathological differences of high Fusobacterium nucleatum levels in colorectal cancer: A review and meta-analysis

Wang, Y., Wen, Y., Wang, J., Lai, X., Xu, Y., Zhang, X., Zhu, X., Ruan, C., & Huang, Y. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.945463 · Cited by 12

SELE gene as a characteristic prognostic biomarker of colorectal cancer

Li, N., Xiao, H., Shen, J., Qiao, X., Zhang, F., Zhang, W., Gao, Y., & Liu, Y. D. (2021) · Journal of International Medical Research · doi:10.1177/03000605211004386 · Cited by 12

Exploring the role of gut microbiota in colorectal liver metastasis through the gut-liver axis

Liu, Q.-L., Zhou, H., Wang, Z., & Chen, Y. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1563184 · Cited by 12

Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome

Duggan, W. P., Salvucci, M., Kısakol, B., Lindner, A. U., Reynolds, I. S., Düßmann, H., Fay, J., O’Grady, T., Longley, D. B., Ginty, F., et al. (2023) · Journal of Molecular Medicine · doi:10.1007/s00109-023-02324-5 · Cited by 10

The relationship between the gastric cancer microbiome and clinicopathological factors: a metagenomic investigation from the 100,000 genomes project and The Cancer Genome Atlas

Booth, M. E., Wood, H. M., Travis, M. A., Ambrose, J. C., Arumugam, P., Bevers, R. P. J., Bleda, M., Boardman-Pretty, F., Boustred, C. R., Brittain, H. K., et al. (2025) · Gastric Cancer · doi:10.1007/s10120-025-01588-9 · Cited by 11

Host Genetics and Microbiota Interactions in Colorectal Cancer: Shared or Independent Risk?

Garmendia, I. R., & García‐Etxebarria, K. (2022) · Microorganisms · doi:10.3390/microorganisms10112129 · Cited by 11

Microbiota regulation in constipation and colorectal cancer

Wang, L., Ruan, H., Wang, B., Qin, Y., & Zhong, W. (2023) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v15.i5.776 · Cited by 11

No Clear Clustering Dysbiosis from Salivary Microbiota Analysis by Long Sequencing Reads in Patients Affected by Oral Squamous Cell Carcinoma: A Single Center Study

Mauceri, R., Coppini, M., Vacca, D., Bertolazzi, G., Cancila, V., Tripodo, C., & Campisi, G. (2023) · Cancers · doi:10.3390/cancers15174211 · Cited by 12

Fusobacterium nucleatum Load Correlates with KRAS Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma

Takeda, K., Koi, M., Okita, Y., Sajibu, S., Keku, T. O., & Carethers, J. M. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0179 · Cited by 11

Modeling the effect of gut microbiome on therapeutic efficacy of immune checkpoint inhibitors against cancer

Chen, Y., & Lai, X. (2022) · Mathematical Biosciences · doi:10.1016/j.mbs.2022.108868 · Cited by 12

Characterization of the Metabolome of Breast Tissues from Non-Hispanic Black and Non-Hispanic White Women Reveals Correlations between Microbial Dysbiosis and Enhanced Lipid Metabolism Pathways in Triple-Negative Breast Tumors

Smith, A., Cao, X., Gu, Q., Amos-Abanyie, E. K., Tolley, E. A., Vidal, G. A., Lyn‐Cook, B. D., & Starlard‐Davenport, A. (2022) · Cancers · doi:10.3390/cancers14174075 · Cited by 11

Fructose, glucose and fat interrelationships with metabolic pathway regulation and effects on the gut microbiota

Szabó, J., Maróti, G., Solymosi, N., Andrásofszky, E., Tuboly, T., Bersényi, A., Bruckner, G. G., & Hullár, I. (2021) · Acta Veterinaria Hungarica · doi:10.1556/004.2021.00022 · Cited by 10

Are intratumoral microbiota involved in the progression of intraductal papillary mucinous neoplasms of the pancreas?

Hozaka, Y., Oi, H., Satake, S., Uchino, Y., Goto, Y., Idichi, T., Tanoue, K., Yamasaki, Y., Kawasaki, Y., Mataki, Y., et al. (2022) · Surgery · doi:10.1016/j.surg.2022.10.003 · Cited by 10

A fluorescence quenching-recovery sensor based on RCA for the specific analysis of Fusobacterium nucleatum. nucleatum

Jiao, J., Li, P., Gu, Y., Du, X., Wang, S., & Wang, J. (2020) · Analytical Biochemistry · doi:10.1016/j.ab.2020.113808 · Cited by 10

Prediction of immunotherapy efficacy and immunomodulatory role of hypoxia in colorectal cancer

Zheng, Z., Bian, C., Wang, H., Su, J., Meng, L., Xin, Y., & Jiang, X. M. (2022) · Therapeutic Advances in Medical Oncology · doi:10.1177/17588359221138383 · Cited by 10

A pilot study on clinicopathological features and intestinal microflora changes in colorectal cancer patients born over a nine-year period encompassing three years before and after the Great Chinese famine

Li, J., Wei, Z., Cao, S., Tan, X., Liu, S., Yao, Z., Sun, T., Li, Y., Zhang, D., & Zhou, Y. (2019) · Cancer Epidemiology · doi:10.1016/j.canep.2019.02.001 · Cited by 10

Fusobacteria alterations are associated with colorectal cancer liver metastasis and a poor prognosis

Jin, M., Fan, Q., Shang, F., Zhang, T., Ogino, S., & Liu, H. (2024) · Oncology Letters · doi:10.3892/ol.2024.14368 · Cited by 9

The emerging role of Fusobacteria in carcinogenesis

Gibbs, R. J., Chambers, A., & Hill, D. J. (2024) · European Journal of Clinical Investigation · doi:10.1111/eci.14353 · Cited by 9

Role of human microbiota in the development of colorectal cancer

Kochkina, S. O., Гордеев, С. С., & Mamedli, Z. Z. (2019) · Surgery and Oncology · doi:10.17650/2686-9594-2019-9-3-11-17 · Cited by 9

The dynamic landscape of parasitemia dependent intestinal microbiota shifting and the correlated gut transcriptome during Plasmodium yoelii infection

Yawen, Z., Xiangyun, C., Liao, B., Ye, X., Liu, T., Zhou, X., Li, J., Lei, C., Xu, W., & Biao, R. (2022) · Microbiological Research · doi:10.1016/j.micres.2022.126994 · Cited by 9

The role of Fusobacteria in oral cancer and immune evasion

Harrandah, A. M. (2023) · Current Opinion in Oncology · doi:10.1097/cco.0000000000000927 · Cited by 9

Butyrogenic effect of galactosyl and mannosyl carbohydrates and their regulation on piglet intestinal microbiota

Cao, L., Liu, Z., Yu, Y., Liang, Q., Wei, X., Sun, H., Fang, Y., Zhu, C., Kong, Q., Fu, X., et al. (2023) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-023-12436-0 · Cited by 9

Fusobacterium nucleatum and the Immune System in Colorectal Cancer

Borroni, E. M., Qehajaj, D., Farina, F. M., Yiu, D., Bresalier, R. S., Chiriva‐Internati, M., Mirandola, L., Štifter, S., Laghi, L., & Grizzi, F. (2019) · Current Colorectal Cancer Reports · doi:10.1007/s11888-019-00442-2 · Cited by 9

Screening of immunosuppressive cells from colorectal adenocarcinoma and identification of prognostic markers

Li, F., Zhou, J., Li, Z., & Zhang, L. (2021) · Bioscience Reports · doi:10.1042/bsr20203496 · Cited by 9

Exploring the Interplay: Oral–Gut Microbiome Connection and the Impact of Diet and Nutrition

Parveen, S., Alqahtani, A. S., Aljabri, M. Y., Dawood, T., Khan, S. S., Gupta, B., Vempalli, S., Hassan, A. A.-H. A.-A., & Elamin, N. M. H. (2024) · European Journal of General Dentistry · doi:10.1055/s-0044-1786154 · Cited by 11

Effect of a Novel Food Rich in Miraculin on the Intestinal Microbiome of Malnourished Patients with Cancer and Dysgeusia

Plaza‐Díaz, J., Brandimonte‐Hernández, M., Plaza, B. L., Ruiz‐Ojeda, F. J., Álvarez‐Mercado, A. I., Arcos-Castellanos, L., Feliú, J., Hummel, T. R., Milla, S. P., & Gil, Á. (2025) · Nutrients · doi:10.3390/nu17020246 · Cited by 8

Genetic heterogeneity of colorectal cancer and the microbiome

Senchukova, M. A. (2023) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v15.i3.443 · Cited by 9

Pathways Related to Colon Inflammation Are Associated with Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study

Kibriya, M. G., Jasmine, F., Pekow, J. R., Munoz, A., Weber, C. R., Raza, M., Kamal, M., Ahsan, H., & Bissonnette, M. (2023) · Cancers · doi:10.3390/cancers15112921 · Cited by 8

Metagenomic analysis fecal microbiota of dysentery-like diarrhoea in a pig farm using next-generation sequencing

Chen, X., Guo, Q., Li, Y., Song, T.-Y., & Ge, J. Q. (2023) · Frontiers in Veterinary Science · doi:10.3389/fvets.2023.1257573 · Cited by 8

Differences in mortality in Fusobacterium necrophorum and Fusobacterium nucleatum infections detected by culture and 16S rRNA gene sequencing

Johannesen, K. M., Kolekar, S., Greve, N., Nielsen, X. C., Barfod, T. S., & Bødtger, U. C. S. (2018) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-018-3394-4 · Cited by 8

Oral Microbiota, a Potential Determinant for the Treatment Efficacy of Gastric Helicobacter pylori Eradication in Humans

Chen, H.-X., Xie, H., Shao, D., Chen, L., Chen, S., Wang, L., & Han, X. (2022) · Polish Journal of Microbiology · doi:10.33073/pjm-2022-020 · Cited by 9

A Bioinformatics Tool for Identifying Intratumoral Microbes from the ORIEN Dataset

Wang, C., Ma, A., Li, Y., McNutt, M. E., Zhang, S., Zhu, J., Hoyd, R., Wheeler, C. E., Robinson, L. A., Chan, C. H. F., et al. (2024) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0213 · Cited by 7

Clinical relationships between the intratumoral microbiome and risk factors for head and neck cancer

Hamada, M., Nishiyama, K., Nomura, R., Akitomo, T., Mitsuhata, C., Yura, Y., Nakano, K., Matsumoto‐Nakano, M., Uzawa, N., & Inaba, H. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e39284 · Cited by 7

From dysbiosis to precision therapy: decoding the gut-bladder axis in bladder carcinogenesis

Liu, Z.-Q., Yang, X., Chen, J., Ge, S.-C., Dai, S., Zhu, S., & Xian, Z. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1630726 · Cited by 8

The Crosstalk between Microbiome and Immunotherapeutics: Myth or Reality

Tojjari, A., Abushukair, H. M., & Saeed, A. (2022) · Cancers · doi:10.3390/cancers14194641 · Cited by 9

Multiplexed Immunofluorescence Imaging Reveals an Immune-Rich Tumor Microenvironment in Mucinous Rectal Cancer Characterized by Increased Lymphocyte Infiltration and Enhanced Programmed Cell Death Protein 1 Expression

Duggan, W. P., Kısakol, B., O’Connell, E., Matveeva, A., O’Grady, T., McDonough, E. M., Lindner, A. U., McNamara, D. A., Longley, D. B., Ginty, F., et al. (2022) · Diseases of the Colon & Rectum · doi:10.1097/dcr.0000000000002624 · Cited by 7

Highly Sensitive DNA Testing of Fusobacterium nucleatum in Colorectal Tumors

Hullar, M. A. J., Kahsai, O. J., Hill, C. M., Levy, L., Malen, R. C., Curtis, K. R., Ammar, H., Sillah, A., Reedy, A. M., Lampe, J. W., et al. (2025) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-24-1020 · Cited by 8

Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer

Modarres, M. P., Habibi, M. A., Pashaei, M. R., Mohammadpour, Y., Jazi, K., & Ahmadpour, S. (2024) · Current Cancer Therapy Reviews · doi:10.2174/0115733947270529231116114913 · Cited by 6

Tumour-associated and non-tumour-associated bacteria co-abundance groups in colorectal cancer

Liang, Y., Zhang, Q., Yu, J., Hu, W., Xu, S., Xiao, Y., Ding, H., Zhou, J., & Chen, H. (2024) · BMC Microbiology · doi:10.1186/s12866-024-03402-5 · Cited by 6

Oral Microbiota and the Risk of Gastrointestinal Cancers—A Narrative Literature Review

Knop-Chodyła, K., Kochanowska-Mazurek, A., Piasecka, Z., Głaz, A., Wesołek, E., Syty, K., Forma, A., & Baj, J. (2024) · Pathogens · doi:10.3390/pathogens13090819 · Cited by 6

La asociación entre Fusobacterium nucleatum y el cáncer colorrectal: una revisión sistemática y metaanálisis

Villar-Ortega, P., Ruíz, M. E., Gutiérrez-Soto, M., Jiménez, M. R.-C., Navarro‐Marí, J. M., & Fernández, J. G. (2021) · Enfermedades Infecciosas y Microbiología Clínica · doi:10.1016/j.eimc.2021.01.005 · Cited by 6

Nervous system–gut microbiota–immune system axis: future directions for preventing tumor

Wang, J., Cheng, W., & Yang, R. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1535955 · Cited by 7

Interaction between Gut Microbiota and Dendritic Cells in Colorectal Cancer

Zaher, K. A., & Basingab, F. S. (2023) · Biomedicines · doi:10.3390/biomedicines11123196 · Cited by 5

Unveiling the hidden link between oral flora and colorectal cancer: a bidirectional Mendelian randomization analysis and meta-analysis

Zhang, Z., Wu, W., Xiahou, Z., & Song, Y. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1451160 · Cited by 5

Advancements in Understanding and Preventing Obesity-Related Colon Cancer

Shieh, C., Thompson, H. J., McLaughlin, E. M., Chiang, C., & Hussan, H. (2024) · The Cancer Journal · doi:10.1097/ppo.0000000000000744 · Cited by 5

The Role of the Intestinal Microbiome in the Immunotherapy of Colon Cancer

Хакимова, Г. Г., Tryakin, A. A., Заботина, Т. Н., Цуканов, А. С., Алиев, В. А., & Гуторов, С. Л. (2019) · Malignant tumours · doi:10.18027/2224-5057-2019-9-2-5-11 · Cited by 5

Oral Bacteria and Bowel Diseases – Mini Review

Yoneda, M., & Suzuki, N. (2016) · Journal of Gastrointestinal & Digestive System · doi:10.4172/2161-069x.1000404 · Cited by 5

Role of immune escape in different digestive tumours

Du, X.-Z., Wen, B., Liu, L., Wei, Y., & Zhao, K. (2021) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i34.10438 · Cited by 5

Transcriptomic landscape of sodium butyrate-induced growth inhibition of human colorectal cancer organoids

Li, F., Wu, Y., Yan, Y., Wu, S., Zhu, J., Zhang, G., Zhang, P., Yuan, L., Zeng, Y., & Liu, Z. (2022) · Molecular Omics · doi:10.1039/d2mo00127f · Cited by 5

Meta-analyses of host metagenomes from colorectal cancer patients reveal strong relationship between colorectal cancer-associated species

Escalona, M. A. R., Poloni, J. D. F., Krause, M. J., & Dorn, M. (2023) · Molecular Omics · doi:10.1039/d3mo00021d · Cited by 5

Prevalence and Phylogenetic Analysis of Fusobacterium nucleatum and Virulent Factor FadA among Ulcerative Colitis Precancerous and Colorectal Carcinoma Patients in the Iraqi Kurdish Population.

Taher, H. J., & Kamel, F. H. (2023) · PubMed Central · doi:10.22092/ari.2022.360307.2570 · Cited by 5

Mechanistic and Therapeutic Advances in Colon Cancer: A Systematic Review

Xiu-jun, L., Han, Y., Zhang, A., Miao, J., Sun, H., Ge, Y., Wu, F., & Wang, X. (2019) · Open Journal of Proteomics and Genomics · doi:10.17352/ojpg.000008 · Cited by 5

A pilot study of gut mucosal and faecal microbiota in rectal cancer: associations with histological response and adverse events following preoperative chemoradiotherapy

Emoto, S., Inoüe, R., Murai, S., Inagaki, Y., Nozawa, H., Sasaki, K., Murono, K., Kaneko, K., Yokoyama, Y., Abe, S., et al. (2025) · Colorectal Disease · doi:10.1111/codi.70106 · Cited by 4

Gut microbiota and immune modulation: role in neurodegenerative disorders and cancer

Dogra, K. A., Sharma, M., Ghosh, N., Kaur, G., Singh, J., & Sinha, P. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12155-5 · Cited by 6

Patients with Colorectal Cancer

Kenupp, M. G., Vianna, A., Uyeda, M., & Maluf, G. (2024) · International Healthcare Review (online) · doi:10.56226/83 · Cited by 5

Visual analysis of colorectal cancer and gut microbiota: A bibliometric analysis from 2002 to 2022

Long, D., Mao, C., Zhang, Z., Zou, J., & Zhu, Y. (2023) · Medicine · doi:10.1097/md.0000000000035727 · Cited by 4

The Microbiota in Cancer: A Secondary Player or a Protagonist?

García, A. M. G., Lopez-Munoz, F. J., & García‐Rico, E. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46080463 · Cited by 5

Prospects and Challenges of the Study of Anti-Glycan Antibodies and Microbiota for the Monitoring of Gastrointestinal Cancer

Smorodin, E. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111608 · Cited by 4

Dietary Habits and Global Incidence of Colon Cancer

Shinde, S., Sinha, V., Dixit, V., Dwivedi, M. K., Vishvakarma, N. K., Tiwari, A. K., Pandey, S., & Shukla, D. (2021) · Springer eBooks · doi:10.1007/978-3-030-64668-4_2 · Cited by 6

Metagenomics for Gut Microbes

Kumavath, R. N. (2018) · InTech eBooks · doi:10.5772/intechopen.68370 · Cited by 4

Effect of colorectal cancer stem cells on the development and metastasis of colorectal cancer

Deng, R.-Z., Zheng, X., Lu, Z., Yuan, M., Meng, Q.-C., Wu, T., & Tian, Y. (2024) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v16.i11.4354 · Cited by 3

Racial–Ethnic Disparities of Obesity Require Community Context-Specific Biomedical Research for Native Hawaiians and Other Pacific Islanders

Wells, R. K., Torres, A., Mau, M. K. L. M., & Maunakea, A. K. (2024) · Nutrients · doi:10.3390/nu16244268 · Cited by 6

The relationship between pathogenic bacteria and different stages of colorectal cancer

Nezhadi, J., Kafil, H. S., Sadrkabir, M., Mahdavi, F., Moaddab, S. Y., Nouri, R., Mohammadzadeh-Asl, Y., Sattarpour, S., & Rezaee, M. A. (2025) · Letters in Applied Microbiology · doi:10.1093/lambio/ovaf017 · Cited by 3

Infectious Organisms Associated With Colorectal Cancer

Park, M. Y., & Eslick, G. D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-54843-4.00009-x · Cited by 3

Asociación entre infección por Fusobacterium nucleatum y cáncer colorrectal: un estudio mexicano

Cuellar‐Gomez, H., Ocharan-Hernández, M. E., Calzada‐Mendoza, C. C., & Comoto-Santacruz, D. A. (2021) · Revista de Gastroenterología de México · doi:10.1016/j.rgmx.2020.12.002 · Cited by 3

The Association of Diet-Modulated Gut Microbiota on Development and Treatment of Colorectal Cancer

Clinger, E., & Hao, L. (2021) · journal of nutritional oncology · doi:10.34175/jno202104001 · Cited by 3

Development and treatment of colorectal cancer: Insights from multi‐kingdom microbiota

Hong, Y.-M., Song, D., Liu, N., & Wang, H. (2023) · Aging and Cancer · doi:10.1002/aac2.12063 · Cited by 3

Gut microbiota: key facilitator in metastasis of colorectal cancer

Yu, S., Wang, S., Xiong, B., & Peng, C. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1270991 · Cited by 5

Enhancing Colorectal Cancer Screening with Droplet Digital PCR Analysis of Fusobacterium nucleatum in Fecal Immunochemical Test Samples

Datorre, J. G., dos Reis, M. B., de Carvalho, A. C., Porto, J., Rodrigues, G. H., Lima, A. B., Reis, M. T., Hirai, W. Y., HASHIMOTO, C. L., Guimarães, D. P., et al. (2024) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-23-0331 · Cited by 3

Microbiome and Human Malignancies

Saha, A., & Robertson, E. S. (2019) · Current cancer research · doi:10.1007/978-3-030-04155-7_1 · Cited by 3

Metagenomic Approaches for Investigating the Role of the Microbiome in Gut Health and Inflammatory Diseases

Carvalho, R. D. D. O., Carmo, F. L. R. D., da Silva, S. H., Cordeiro, B. F., Vaz, A. B. M., Gimenez, E. G. T., Goulart, L., Goés‐Neto, A., Loir, Y. L., Jan, G., et al. (2018) · InTech eBooks · doi:10.5772/intechopen.72031 · Cited by 4

Cancer Prevention with Molecular Targeted Therapies

Paleari, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158429 · Cited by 3

Uncovering the novel and putative immunogenic targets: Utilizing a reverse vaccinology approach against Fusobacterium nucleatum

Fereshteh, S., Goodarzi, N. N., Bolourchi, N., Asforooshani, M. K., Salimi, A., & Badmasti, F. (2023) · Informatics in Medicine Unlocked · doi:10.1016/j.imu.2023.101359 · Cited by 2

The Human Microbiome: An Invisible Key to Unlocking Wellness

., K., Dubey, M., Kumari, S., & Singh, M. (2025) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.19.1.20 · Cited by 5

Intra-tumor microbiome-based tumor survival indices predict immune interaction and drug sensitivity on pan-cancer scale

Gao, Y., Zhang, H., Chu, D., & Ning, K. (2025) · mSystems · doi:10.1128/msystems.00312-25 · Cited by 2

Contourner la résistance à l’immunothérapie des cancers : interventions centrées sur le microbiome intestinal

Fidelle, M., Derosa, L., Routy, B., & Zitvogel, L. (2021) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/j.banm.2021.01.022 · Cited by 2

Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota–Immunity Axis?

Russo, E., Boem, F., Curini, L., & Amedei, A. (2022) · Interdisciplinary cancer research · doi:10.1007/16833_2022_6 · Cited by 2

[Oral microbiota and inflammatory bowel disease].

Zhang, H., Zhou, X., Xu, X., & Wang, Y. (2019) · PubMed Central · doi:10.7518/hxkq.2019.04.020 · Cited by 2

Can microbiota analysis help intercept cases of colon cancer in case of occult blood negativity, also suggesting possible pharmacological intervention strategies?

Pierro, F. D., Bertuccioli, A., Cazzaniga, M., Matera, M., Cavecchia, I., Gerardi, V., Piccirelli, S., Salvi, D., Pugliano, C. L., Cesaro, P., et al. (2023) · Minerva Gastroenterology · doi:10.23736/s2724-5985.23.03578-7 · Cited by 2

Class I HLA Allele Predicted Restricted Antigenic Coverages for Fap2 Protein of Fusobacterium Nucleatum Are Associated with Colorectal Cancer Incidence

Zeddou, M. (2023) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2023.24.10.3629 · Cited by 2

Diet, inflammation, and cancer

Chumanevich, A. A., Hébert, J. R., Spicer, M., & Hofseth, L. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822130-3.00016-8 · Cited by 1

Associations Between Fusobacterium nucleatum and msh2, mlh1, and msh6 Gene Expression in Colorectal Cancer

Torkashvand, R., Hajikhani, B., Doust, R. H., Dabiri, H., & Dadashi, M. (2024) · Jundishapur Journal of Microbiology · doi:10.5812/jjm-144247 · Cited by 1

Oral metagenomics changes the game in carcinogenesis

Marzbali, M. Y., Banakar, M., Mousavi, S. M., & Lai, C. W. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13531-6.00007-0 · Cited by 1

Human microbiome, cancer and cancer therapy

Veerasamy, R., Karunakaran, R., & Vasu, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15435-5.00007-4 · Cited by 1

Gut microbiota regulation and Traditional Chinese Medicine syndrome differentiation in right- and left-sided colon cancer heterogeneity — A review

Chen, J., Zhao, J., Zhang, X., & Zhu, H. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1768252 · Cited by 1

Colorectal cancer landscape from gut microbiota: Insights into mutations, epigenetic dysregulation, and immune microenvironment alterations

Li, Y., Yang, Y., Zhang, X., Huang, Z., Zhang, X., & Wen, J. (2026) · Virulence · doi:10.1080/21505594.2026.2696642 · Cited by 1

Abstract 4560: Fusobacterium nucleatum and tumor immunity status according to microsatellite instability in colorectal cancer

Mima, K., Hamada, T., Nishihara, R., Nowak, J. A., Qian, Z. R., Kosumi, K., Giannakis, M., Bullman, S., Baba, H., Huttenhower, C., et al. (2017) · Cancer Research · doi:10.1158/1538-7445.am2017-4560

Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

Hamada, T., Zhang, X., Mima, K., Bullman, S., Sukawa, Y., Nowak, J. A., Kosumi, K., Masugi, Y., Twombly, T. S., Cao, Y., et al. (2018) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-18-0174 · Cited by 237

Fusobacterium nucleatum and T Cells in Colorectal Carcinoma

Mima, K., Sukawa, Y., Nishihara, R., Qian, Z. R., Yamauchi, M., Inamura, K., Kim, S. A., Masuda, A., Nowak, J. A., Nosho, K., et al. (2015) · JAMA Oncology · doi:10.1001/jamaoncol.2015.1377 · Cited by 669

Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

Borowsky, J., Haruki, K., Lau, M. C., Costa, A. D., Väyrynen, J. P., Ugai, T., Arima, K., da Silva, A., Felt, K. D., Zhao, M. M., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-4009 · Cited by 110

Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis

Mima, K., Nishihara, R., Qian, Z. R., Cao, Y., Sukawa, Y., Nowak, J. A., Yang, J., Dou, R., Masugi, Y., Song, M., et al. (2016) · Gut · doi:10.1136/gutjnl-2015-310101 · Cited by 1,080