Cited by 44Neural and Behavioral Psychology StudiesSchizophrenia research and treatmentNeural dynamics and brain function

P50 sensory gating is related to performance on select tasks of cognitive inhibition

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Yadon, Carly A., Bugg, Julie M., Kisley, Michael A., Davalos, Deana B.·2009·Cognitive, Affective, & Behavioral Neuroscience

Abstract

P50 suppression deficits have been documented in clinical and nonclinical populations, but the behavioral correlates of impaired auditory sensory gating remain poorly understood. In the present study, we examined the relationship between P50 gating and healthy adults' performance on cognitive inhibition tasks. On the basis of load theory (Lavie, Hirst, de Fockert, & Viding, 2004), we predicted that a high perceptual load, a possible consequence of poor auditory P50 sensory gating, would have differential (i.e., positive vs. negative) effects on performance of cognitive inhibition tasks. A dissociation was observed such that P50 gating was negatively related to interference resolution on a Stroop task and positively related to response inhibition on a go/no-go task. Our findings support the idea that a high perceptual load may be beneficial to Stroop performance because of the reduced processing of distractors but detrimental to performance on the go/no-go task because of interference with stimulus discrimination.

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  1. Marlow-O’Conner 2005 fMRI indices of frontal activation associated with sensory gating deficits in schizophrenia Dissertation Abstracts International 66B 3417

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Authors
Yadon, C. A., Bugg, J. M., Kisley, M. A., & Davalos, D. B.
Affiliations
  • Colorado State University (US)
  • Washington University in St. Louis (US)
  • University of Colorado Colorado Springs (US)
Corresponding author
Yadon, Carly A.
Venue
Cognitive, Affective, & Behavioral Neuroscience
Published
2009-12
Volume
9
Issue
4
Pages
448-458
ISSN
  • 1530-7026 (ISSN-L)
  • 1531-135X
OpenAlex
W2146448218
Cited by
43
References
76
Citations by year
2026: 2 · 2025: 5 · 2024: 2 · 2023: 6 · 2022: 2 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 7 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 3 · 2013: 1 · 2012: 2
FWCI
0.48
Type
journal article
Language
en
Open access
Locations
  • Cognitive Affective & Behavioral Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • BearWorks (Missouri State University) (submittedVersion)
Funders
National Institute on Aging (5 T32 AG 00030, T32AG000030)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
auditory gating, cognitive inhibition, perceptual load, load theory, Stroop interference, response inhibition, go/no-go task, distractor processing, stimulus discrimination, healthy adults
MeSH terms
Acoustic Stimulation, Adolescent, Adult, Cognition, Electroencephalography, Evoked Potentials, Auditory, Female, Humans, Inhibition, Psychological, Male, Neuropsychological Tests, Psychomotor Performance, Sensory Gating

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