Relationship between Sleep Disorders and the Risk for Developing Type 2 Diabetes Mellitus
Abstract
Sleep is increasingly being recognized as an important factor in the homeostasis of multiple body functions, including blood glucose metabolism. One of the most common sleep disorders, obstructive sleep apnea, is not only highly prevalent in patients with type 2 diabetes mellitus, but may contribute to the development of abnormalities in blood glucose metabolism. Evidence suggests that effectively treating sleep apnea, specifically with continuous positive airway pressure, improves glycemic and nonglycemic outcomes. Other common sleep disorders, such as insufficient sleep, shift work disorder, and restless legs syndrome, may also have a significant influence on the development and management of diabetes and its complications. The purpose of this article is to review the recent literature on the relationship between sleep disorders and blood glucose metabolism.
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Sleep deprivation alters glucose homeostasis, leading to insulin resistance and risk of diabetes.
“Sleep deprivation alters glucose homeostasis, leading to insulin resistance and risk of diabetes(17, 18, 24, 59-61).”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [59]
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Sleep: important considerations for the prevention of cardiovascular disease
Grandner, M. A., Alfonso-Miller, P., Fernandez-Mendoza, J., Shetty, S., Shenoy, S., & Combs, D. (2016) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000324 · Cited by 166 · see citing works
- Authors
- Ioja, S., Weir, I. D., & Rennert, N. J.
- Affiliations
- Norwalk Hospital (US)
- Corresponding author
- Ioja, Simona
- ORCID
- Ioja, Simona
- Venue
- Postgraduate Medicine
- Publisher
- Informa UK Limited
- Published
- 2012-07
- Volume
- 124
- Issue
- 4
- Pages
- 119-129
- ISSN
- 0032-5481 (ISSN-L)
- 1941-9260
- OpenAlex
- W2042945987
- Cited by
- 32
- References
- 14
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 3 · 2016: 6 · 2015: 3 · 2014: 4 · 2013: 2
- FWCI
- 0.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Postgraduate Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- sleep disorders, type 2 diabetes, obstructive sleep apnea, blood glucose metabolism, continuous positive airway pressure, insufficient sleep, shift work disorder, restless legs syndrome, diabetes complications
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Type 2, Humans, Risk, Risk Factors, Sleep Wake Disorders, Prevalence, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure, Diabetes Complications
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