Cobalamin and folate status predicts mental development scores in North Indian children 12–18 mo of age

Strand, Tor A; Taneja, Sunita; Ueland, Per M; Refsum, Helga; Bahl, Rajiv; Schneede, Joern; Sommerfelt, Halvor; Bhandari, Nita

doi:10.3945/ajcn.111.032268

Cited by 108Folate and B Vitamins ResearchChild Nutrition and Water AccessIron Metabolism and Disorders

Cobalamin and folate status predicts mental development scores in North Indian children 12–18 mo of age

Open access

Strand, Tor A, Taneja, Sunita, Ueland, Per M, Refsum, Helga, Bahl, Rajiv, Schneede, Joern, Sommerfelt, Halvor, Bhandari, Nita·2013·The American Journal of Clinical Nutrition

DOI 10.3945/ajcn.111.032268

Open this paper in CoChat — free account

Abstract

Background Micronutrient deficiencies can affect cognitive function. Many young children in low- and middle-income countries have inadequate cobalamin (vitamin B-12) status.Objective The objective was to measure the association of plasma concentrations of folate, cobalamin, total homocysteine, and methylmalonic acid with cognitive performance at 2 occasions, 4 mo apart, in North Indian children aged 12-18 mo.Design Bayley Scales of Infant Development II were used to assess cognition. In multiple regression models adjusted for several potential confounders, we measured the association between biomarkers for folate and cobalamin status and psychomotor or mental development scores on the day of blood sampling and 4 mo thereafter.Results Each 2-fold increment in plasma cobalamin concentration was associated with a significant increment in the mental development index score of 1.3 (95% CI: 0.2, 2.4; P = 0.021). Furthermore, each 2-fold increment in homocysteine or methylmalonic acid concentration was associated with a decrement in mental development index score of 2.0 (95% CI: 0.5, 3.4; P = 0.007) or 1.1 (95% CI: 0.3, 1.8; P = 0.004) points, respectively. Plasma folate concentration was significantly and independently associated with mental development index scores only when children with poor cobalamin status were excluded, ie, in those who had cobalamin concentrations below the 25th percentile. None of these markers was associated with psychomotor scores in the multiple regression models.Conclusions Cobalamin and folate status showed a statistically significant association with cognitive performance. Given the high prevalence of deficiencies in these nutrients, folate and cobalamin supplementation trials are required to measure any beneficial effect on cognition.

Integrity signals

Registry

Crossref · 10.3945/ajcn.111.032268

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

An increase in tHcy and MMA may indicate that poor B-12 status has reached a level that has negative consequences for neurodevelopment.
“An increase in these markers may indicate that poor B-12 status has reached a level that has negative consequences for neurodevelopment (16,17).”
From Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children (2017) · cites this paper as [17]

Bayley Scales of Infant Development
(2007) · Sage eBooks · doi:10.4135/9781412952644.n48 · Cited by 4,242 · see citing works
WHO Child Growth Standards based on length/height, weight and age
de Onís, M. (2006) · Acta Paediatrica · doi:10.1111/j.1651-2227.2006.tb02378.x · Cited by 3,991 · see citing works
Developmental potential in the first 5 years for children in developing countries
Grantham-McGregor, S., Cheung, Y. B., Cueto, S., Glewwe, P., Richter, L., & Strupp, B. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60032-4 · Cited by 3,630 · see citing works
Bayley Scales of Infant Development
Lennon, E. M., Gardner, J. M., Karmel, B. Z., & Flory, M. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.23376-2 · Cited by 1,310 · see citing works
Breast-feeding and cognitive development: a meta-analysis
Anderson, J. W., Johnstone, B. M., & Remley, D. T. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.4.525 · Cited by 1,276 · see citing works
Strategies to avoid the loss of developmental potential in more than 200 million children in the developing world
Engle, P. L., Black, M. M., Behrman, J. R., Cabral de Mello, M., Gertler, P. J., Kapiriri, L., Martorell, R., & Young, M. E. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60112-3 · Cited by 1,151 · see citing works
Breastfeeding and Child Cognitive Development: New Evidence From a Large Randomized Trial
Kramer, M. S. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.5.578 · Cited by 1,016 · see citing works
Modelling and Smoothing Parameter Estimation With Multiple Quadratic Penalties
Wood, S. N. (2000) · Journal of the Royal Statistical Society Series B (Statistical Methodology) · doi:10.1111/1467-9868.00240 · Cited by 727 · see citing works
The metabolism of homocysteine: pathways and regulation
Finkelstein, J. D. (1998) · European Journal of Pediatrics · doi:10.1007/pl00014300 · Cited by 605 · see citing works
Micronutrient deficiencies and cognitive functioning
Black, M. M. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.11.3927s · Cited by 438 · see citing works
Microbiological assay for serum, plasma, and red cell folate using cryopreserved, microtiter plate method
Molloy, A. M., & Scott, J. M. (1997) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(97)81007-5 · Cited by 433 · see citing works
Effects of Vitamin B <sub>12</sub> and Folate Deficiency on Brain Development in Children
Black, M. M. (2008) · Food and Nutrition Bulletin · doi:10.1177/15648265080292s117 · Cited by 393 · see citing works
Vitamin B <sub>12</sub> -Folate Interrelationships
Shane, B., & Stokstad, E. L. R. (1985) · Annual Review of Nutrition · doi:10.1146/annurev.nu.05.070185.000555 · Cited by 311 · see citing works
Microbiological assay on microtitre plates of folate in serum and red cells.
O’Broin, S. D., & Kelleher, B. (1992) · Journal of Clinical Pathology · doi:10.1136/jcp.45.4.344 · Cited by 306 · see citing works
Cerebral folate deficiency
Ramaekers, V. T., & Blau, N. (2004) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2004.tb00451.x · Cited by 201 · see citing works
Cerebral folate deficiency
Ramaekers, V. T., & Blau, N. (2004) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162204001471 · Cited by 192 · see citing works
Folate–vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency
Selhub, J., Morris, M. S., Jacques, P. F., & Rosenberg, I. H. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26947c · Cited by 189 · see citing works
Signs of impaired cognitive function in adolescents with marginal cobalamin status
Louwman, M. W., van Dusseldorp, M., van de Vijver, F. J., Thomas, C. M., Schneede, J., Ueland, P. M., Refsum, H., & van Staveren, W. A. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.3.762 · Cited by 178 · see citing works
Self-citation
Kenyan School Children Have Multiple Micronutrient Deficiencies, but Increased Plasma Vitamin B-12 Is the Only Detectable Micronutrient Response to Meat or Milk Supplementation
Siekmann, J. H., Allen, L. H., Bwibo, N. O., Demment, M. W., Murphy, S. P., & Neumann, C. G. (2003) · Journal of Nutrition · doi:10.1093/jn/133.11.3972s · Cited by 175 · see citing works
Substantial reduction in severe diarrheal morbidity by daily zinc supplementation in young north Indian children
Bhandari, N., Bahl, R., Taneja, S., Strand, T., Mølbak, K., Ulvik, R. J., Sommerfelt, H., & Bhan, M. K. (2002) · PEDIATRICS · doi:10.1542/peds.109.6.e86 · Cited by 158 · see citing works
Self-citation
Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum
Bhandari, N., Bahl, R., Taneja, S., Strand, T. A., Mølbak, K., Ulvik, R. J., Sommerfelt, H., & Bhan, M. K. (2002) · BMJ · doi:10.1136/bmj.324.7350.1358 · Cited by 147 · see citing works
Self-citation
Cobalamin and folate status in infants and young children in a low-to-middle income community in India
Taneja, S., Bhandari, N., Strand, T. A., Sommerfelt, H., Refsum, H., Ueland, P. M., Schneede, J., Bahl, R., & Bhan, M. K. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1302 · Cited by 132 · see citing works
Self-citation
Vitamin B-12 and cognition in the elderly
Smith, A. D., & Refsum, H. (2008) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26947d · Cited by 125 · see citing works
Self-citation
Folate status and the immune system.
Dhur, A., Galán, P., & Herçberg, S. (1991) · PubMed · Cited by 120 · see citing works
Substantial reduction in severe diarrheal morbidity by daily zinc supplementation in young north Indian children
(2003) · The Indian Journal of Pediatrics · doi:10.1007/bf02725586 · Cited by 119 · see citing works
Simultaneous profile analysis of plasma amino and organic acids by capillary gas chromatography
Hušek, P. (1995) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/0378-4347(95)00115-y · Cited by 118 · see citing works
Methylmalonic acid and homocysteine in plasma as indicators of functional cobalamin deficiency in infants on macrobiotic diets
Schneede, J., Dagnelie, P. C., Van Staveren, W. A., Vollset, S. E., Refsum, H., & Ueland, P. M. (1994) · Pediatric Research · doi:10.1203/00006450-199408000-00010 · Cited by 101 · see citing works
Self-citation
Breastfeeding Duration and Academic Achievement at 10 Years
Oddy, W. H., Li, J., Whitehouse, A., Zubrick, S. R., & Malacova, E. (2010) · PEDIATRICS · doi:10.1542/peds.2009-3489 · Cited by 89 · see citing works
Folate and cobalamin status in relation to breastfeeding and weaning in healthy infants
Hay, G., Johnston, C., Whitelaw, A., Trygg, K. U., & Refsum, H. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.1.105 · Cited by 82 · see citing works
Self-citation
Cellular folate vitamer distribution during and after correction of vitamin B 12 deficiency: a case for the methylfolate trap
Smulders, Y. M., Smith, D. E. C., Kok, R. M., Teerlink, T., Swinkels, D. W., Stehouwer, C. D. A., & Jakobs, C. (2005) · British Journal of Haematology · doi:10.1111/j.1365-2141.2005.05913.x · Cited by 81 · see citing works
Microbiological assay for vitamin B12 with use of a colistin-sulfate-resistant organism.
Kelleher, B. P., Walshe, K., Scott, J. M., & O’Broin, S. D. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.1.52 · Cited by 72 · see citing works
Growth Indices, Anemia, and Diet Independently Predict Motor Milestone Acquisition of Infants in South Central Nepal
Siegel, E. H., Stoltzfus, R. J., Kariger, P. K., Katz, J., Khatry, S. K., LeClerq, S. C., Pollitt, E., & Tielsch, J. M. (2005) · Journal of Nutrition · doi:10.1093/jn/135.12.2840 · Cited by 62 · see citing works
Prevalence of cobalamin (vitamin B-12) and folate deficiency in India— audi alteram partem
Antony, A. C. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.2.157 · Cited by 61 · see citing works
Biochemical pathogenesis of subacute combined degeneration of the spinal cord and brain
Surtees, R. A. H. (1993) · Journal of Inherited Metabolic Disease · doi:10.1007/bf00711908 · Cited by 59 · see citing works
B Vitamins: Proposed Fortification Levels for Complementary Foods for Young Children
Allen, L. H. (2003) · Journal of Nutrition · doi:10.1093/jn/133.9.3000s · Cited by 40 · see citing works
Nutritional status of infants aged 4 to 18 months on macrobiotic diets and matched omnivorous control infants: a population-based mixed-longitudinal study. II. Growth and psychomotor development.
Dagnelie, P. C., van Staveren, W. A., Vergote, F. J., BUREMA, J., Hof, M. A. V., van Klaveren, J. D., & Hautvast, J. G. A. J. (1989) · PubMed · Cited by 39 · see citing works
Impact of zinc supplementation on mental and psychomotor scores of children aged 12 to 18 months: A randomized, double-blind trial
Taneja, S., Bhandari, N., Bahl, R., & Bhan, M. K. (2005) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2004.10.061 · Cited by 38 · see citing works
Self-citation
Folate, but not vitamin B-12 status, predicts respiratory morbidity in north Indian children.
Strand, T., Taneja, S., Bhandari, N., Refsum, H., Ueland, P., Gjessing, H., Bahl, R., Schneede, J., Bhan, M., & Sommerfelt, H. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.1.139 · Cited by 30 · see citing works
Self-citation

Flagged first, then by citations

Sorted by citations

Nutrition and brain development in early life
Prado, E. L., & Dewey, K. G. (2014) · Nutrition Reviews · doi:10.1111/nure.12102 · Cited by 1,036 · see citing works
Vitamin B12 deficiency
Green, R., Allen, L. H., Bjørke-Monsen, A.-L., Brito, A., Guéant, J.-L., Miller, J. W., Molloy, A. M., Nexo, E., Stabler, S., Toh, B.-H., et al. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.40 · Cited by 970 · see citing works
Self-citation
Biomarkers of Nutrition for Development (BOND): Vitamin B-12 Review
Allen, L. H., Miller, J. W., de Groot, C. P. G. M., Rosenberg, I. H., Smith, A. D., Refsum, H., & Raiten, D. J. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy201 · Cited by 303 · see citing works
Self-citation
Vitamin B12 Intake From Animal Foods, Biomarkers, and Health Aspects
Obeid, R., Heil, S. G., Verhoeven, M. M. A., van den Heuvel, E. G. H. M., de Groot, C. P. G. M., & Eussen, S. J. P. M. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00093 · Cited by 210 · see citing works
Vitamin B12
Smith, A. D., Warren, M. J., & Refsum, H. (2018) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2017.11.005 · Cited by 184 · see citing works
Self-citation
Vitamin B-12 Supplementation during Pregnancy and Early Lactation Increases Maternal, Breast Milk, and Infant Measures of Vitamin B-12 Status
Duggan, C., Srinivasan, K., Thomas, T. S., Samuel, T. M., Rajendran, R., Muthayya, S., Finkelstein, J. L., Lukose, A., Fawzi, W. W., Allen, L. H., et al. (2014) · Journal of Nutrition · doi:10.3945/jn.113.187278 · Cited by 165 · see citing works
Nutritional Support of Neurodevelopment and Cognitive Function in Infants and Young Children—An Update and Novel Insights
Kadosh, K. C., Muhardi, L., Parikh, P., Basso, M., Mohamed, H. J. J., Prawitasari, T., Samuel, F. O., Ma, G., & Geurts, J. M. W. (2021) · Nutrients · doi:10.3390/nu13010199 · Cited by 186 · see citing works
Emerging roles for folate and related B-vitamins in brain health across the lifecycle
McGarel, C., Pentieva, K. D., Strain, J. J., & McNulty, H. (2014) · Proceedings of The Nutrition Society · doi:10.1017/s0029665114001554 · Cited by 141 · see citing works
Vitamin B-12 and Cognition in Children
Venkatramanan, S., Armata, I. E., Strupp, B. J., & Finkelstein, J. L. (2016) · Advances in Nutrition · doi:10.3945/an.115.012021 · Cited by 138 · see citing works
Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children
Kvestad, I., Hysing, M., Shrestha, M., Ulak, M., Thorne-Lyman, A. L., Henjum, S., Ueland, P. M., Midttun, Ø., Fawzi, W., Chandyo, R. K., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.144931 · Cited by 92 · see citing works
Self-citation
Homocysteine and cognition: A systematic review of 111 studies
Setién‐Suero, E., Suárez‐Pinilla, M., Suárez‐Pinilla, P., Crespo‐Facorro, B., & Ayesa‐Arriola, R. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.014 · Cited by 86 · see citing works
Neurocognitive functioning and genetic variation in patients with primary brain tumours
Wefel, J. S., Noll, K. R., & Scheurer, M. E. (2016) · The Lancet Oncology · doi:10.1016/s1470-2045(15)00380-0 · Cited by 76 · see citing works
Vitamin B12 and Folic Acid Improve Gross Motor and Problem-Solving Skills in Young North Indian Children: A Randomized Placebo-Controlled Trial
Kvestad, I., Taneja, S., Kumar, T., Hysing, M., Refsum, H., Yajnik, C. S., Bhandari, N., Strand, T. A., & Folate and Vitamin B12 Study Group (2015) · PLoS ONE · doi:10.1371/journal.pone.0129915 · Cited by 74 · see citing works
Self-citation
Assessment of Neurodevelopment, Nutrition, and Inflammation From Fetal Life to Adolescence in Low-Resource Settings
Suchdev, P. S., Boivin, M. J., Forsyth, B. W. C., Georgieff, M., Guerrant, R. L., & Nelson, C. A. (2017) · PEDIATRICS · doi:10.1542/peds.2016-2828e · Cited by 71 · see citing works
Effects of maternal vitamin B12 supplementation on early infant neurocognitive outcomes: a randomized controlled clinical trial
Srinivasan, K., Thomas, T. S., Kapanee, A. R. M., Ramthal, A., Bellinger, D. C., Bosch, R. J., Kurpad, A. V., & Duggan, C. (2016) · Maternal and Child Nutrition · doi:10.1111/mcn.12325 · Cited by 64 · see citing works
Cobalamin Status from Pregnancy to Early Childhood: Lessons from Global Experience
Obeid, R., Murphy, M. M., Solé-Navais, P., & Yajnik, C. S. (2017) · Advances in Nutrition · doi:10.3945/an.117.015628 · Cited by 64 · see citing works
Prevalence of vitamin B12 deficiency in healthy Indian school‐going adolescents from rural and urban localities and its relationship with various anthropometric indices: a cross‐sectional study
Chakraborty, S., Chopra, M., Mani, K., Giri, A. K., Banerjee, P., Sahni, N. S., Siddhu, A., Tandon, N., & Bharadwaj, D. (2018) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12541 · Cited by 56 · see citing works
Oral vitamin B 12 treatment is effective for children with nutritional vitamin B 12 deficiency
Bahadır, A., Reis, P. G., & Erduran, E. (2014) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.12652 · Cited by 52 · see citing works
Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study
Awasthi, S., Kumar, D., Mahdi, A. A., Agarwal, G. G., Pandey, A. K., Parveen, H., Singh, S., Awasthi, R., Pande, H., Anish, T. S., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0267003 · Cited by 48 · see citing works
Effect of Maternal Vitamin B12 Supplementation on Cognitive Outcomes in South Indian Children: A Randomized Controlled Clinical Trial
Thomas, S., Thomas, T. S., Bosch, R. J., Ramthal, A., Bellinger, D. C., Kurpad, A. V., Duggan, C., & Srinivasan, K. (2018) · Maternal and Child Health Journal · doi:10.1007/s10995-018-2605-z · Cited by 48 · see citing works
Maternal plasma vitamin B12 concentrations during pregnancy and infant cognitive outcomes at 2 years of age
Lai, J. S., Ayob, M. N. M., Cai, S., Quah, P. L., Gluckman, P. D., Shek, L. P., Yap, F. K. P., Tan, K. H., Chong, Y. S., Godfrey, K. M., et al. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519000746 · Cited by 44 · see citing works
Prevalence of Vitamin B12 and Folate Deficiencies in Indian Children and Adolescents
Shalini, T., Pullakhandam, R., Ghosh, S., Kulkarni, B., Rajkumar, H., Sachdev, H. S., Kurpad, A. V., & Reddy, G. B. (2023) · Nutrients · doi:10.3390/nu15133026 · Cited by 43 · see citing works
Age dependent levels of plasma homocysteine and cognitive performance
Agrawal, A., Ilango, K., Singh, P. K., Karmakar, D., Singh, G. P. I., Kumari, R., & Dubey, G. P. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.01.016 · Cited by 43 · see citing works
Does early vitamin B12 supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania
Winje, B. A., Kvestad, I., Krishnamachari, S., Manji, K. P., Taneja, S., Bellinger, D. C., Bhandari, N., Bisht, S., Darling, A. M., Duggan, C., et al. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-018962 · Cited by 43 · see citing works
Self-citation
Effects of vitamin B12 supplementation on neurodevelopment and growth in Nepalese Infants: A randomized controlled trial
Strand, T. A., Ulak, M., Hysing, M., Ranjitkar, S., Kvestad, I., Shrestha, M., Ueland, P. M., McCann, A., Shrestha, P. S., Shrestha, L., et al. (2020) · PLoS Medicine · doi:10.1371/journal.pmed.1003430 · Cited by 41 · see citing works
Self-citation
Pre-conceptional Maternal Vitamin B12 Supplementation Improves Offspring Neurodevelopment at 2 Years of Age: PRIYA Trial
D’souza, N., Behere, R. V., Patni, B., Deshpande, M., Bhat, D., Bhalerao, A., Sonawane, S., Shah, R., Ladkat, R., Yajnik, P., et al. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.755977 · Cited by 40 · see citing works
Vitamin Status among Breastfed Infants in Bhaktapur, Nepal
Ulak, M., Chandyo, R. K., Thorne‐Lyman, A., Henjum, S., Ueland, P. M., Midttun, Ø., Shrestha, P. S., Fawzi, W. W., Graybill, L. A., & Strand, T. A. (2016) · Nutrients · doi:10.3390/nu8030149 · Cited by 39 · see citing works
Self-citation
The effect of vitamin B12 supplementation during pregnancy on infant growth and development in Nepal: a community-based, double-blind, randomised, placebo-controlled trial
Chandyo, R. K., Kvestad, I., Ulak, M., Ranjitkar, S., Hysing, M., Shrestha, M., Schwinger, C., McCann, A., Ueland, P. M., Basnet, S., et al. (2023) · The Lancet · doi:10.1016/s0140-6736(23)00346-x · Cited by 40 · see citing works
Self-citation
South Asian Ethnicity Is Related to the Highest Risk of Vitamin B12 Deficiency in Pregnant Canadian Women
Jeruszka-Bielak, M., Isman, C., Schroder, T. H., Li, W., Green, T., & Lamers, Y. (2017) · Nutrients · doi:10.3390/nu9040317 · Cited by 37 · see citing works
Perspective: Practical Approach to Preventing Subclinical B12 Deficiency in Elderly Population
Vincenti, A., Bertuzzo, L., Limitone, A., D’Antona, G., & Cena, H. (2021) · Nutrients · doi:10.3390/nu13061913 · Cited by 34 · see citing works
Developmental Outcome in Children with Malnutrition
Chattopadhyay, N., & Saumitra, M. (2016) · Journal of Nepal Paediatric Society · doi:10.3126/jnps.v36i2.14619 · Cited by 33 · see citing works
The relationship between dietary micronutrients intake and cognition test performance among school‐aged children in government‐owned primary schools in Kumasi metropolis, Ghana
Annan, R. A., Apprey, C., Asamoah‐Boakye, O., Okonogi, S., Yamauchi, T., & Sakurai, T. (2019) · Food Science & Nutrition · doi:10.1002/fsn3.1162 · Cited by 33 · see citing works
Methylmalonic Acid Quantified in Dried Blood Spots Provides a Precise, Valid, and Stable Measure of Functional Vitamin B-12 Status in Healthy Women
Schroder, T. H., Quay, T. A. W., & Lamers, Y. (2014) · Journal of Nutrition · doi:10.3945/jn.114.194829 · Cited by 33 · see citing works
The effect of vitamin B12 supplementation in Nepalese infants on growth and development: study protocol for a randomized controlled trial
Strand, T. A., Ulak, M., Chandyo, R. K., Kvestad, I., Hysing, M., Shrestha, M., Basnet, S., Ranjitkar, S., Shrestha, L., & Shrestha, P. S. (2017) · Trials · doi:10.1186/s13063-017-1937-0 · Cited by 32 · see citing works
Self-citation
DTI Correlates of Cognition in Conventional MRI of Normal-Appearing Brain in Patients with Clinical Features of Subacute Combined Degeneration and Biochemically Proven Vitamin B12 Deficiency
Gupta, P. K., Gupta, R. K., Garg, R. K., Rai, Y., Roy, B., Pandey, C. M., Malhotra, H. S., & Narayana, P. A. (2013) · American Journal of Neuroradiology · doi:10.3174/ajnr.a3785 · Cited by 31 · see citing works
Identification and Quantitation of Malonic Acid Biomarkers of In-Born Error Metabolism by Targeted Metabolomics
Ambati, C. R., Yuan, F., Abu-Elheiga, L. A., Yiqing, Z., & Shetty, V. (2017) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-017-1631-1 · Cited by 30 · see citing works
Vitamin B 12 status and neurodevelopmental delay in Indian infants: a hospital-based cross-sectional study
Azad, C., Jat, K. R., Kaur, J., Guglani, V., Palta, A., Tiwari, A., & Bansal, D. (2019) · Paediatrics and International Child Health · doi:10.1080/20469047.2019.1638130 · Cited by 25 · see citing works
Cobalamin and Folate Status among Breastfed Infants in Bhaktapur, Nepal
Chandyo, R., Ulak, M., Kvestad, I., Hysing, M., Shrestha, M., Ranjitkar, S., Ulvik, A., Ueland, P. M., Shrestha, L., & Strand, T. A. (2018) · Nutrients · doi:10.3390/nu10050639 · Cited by 22 · see citing works
Self-citation
Effects of Childhood-onset Inflammatory Bowel Disease on School Performance: A Nationwide Population-based Cohort Study Using Swedish Health and Educational Registers
Malmborg, P., Mouratidou, N., Sachs, M. C., Hammar, U., Khalili, H., Neovius, M., Hjern, A., Smedby, K. E. E., Ekbom, A., Askling, J., et al. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izz040 · Cited by 21 · see citing works
The effect of infant vitamin B12supplementation on neurodevelopment: a follow-up of a randomised placebo-controlled trial in Nepal
Ulak, M., Kvestad, I., Chandyo, R. K., Ranjitkar, S., Hysing, M., Schwinger, C., Shrestha, M., Basnet, S., Shrestha, L. P., & Strand, T. A. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522000071 · Cited by 20 · see citing works
Self-citation
Micronutrients and cognitive functions among urban school-going children and adolescents: A cross-sectional multicentric study from India
Singh, S., Awasthi, S., Kumar, D., Sarraf, S. R., Pandey, A. K., Agarwal, G. G., Awasthi, A., Anish, T. S., Mathew, J. L., Kar, S., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0281247 · Cited by 19 · see citing works
Evidence for potential underestimation of clinical folate deficiency in resource-limited countries using blood tests
Antony, A. C. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nux032 · Cited by 19 · see citing works
Vitamin B12 Deficiency in Pregnancy and Lactation: Is there a Need for Pre and Post-natal Supplementation?
Siddiqua, T. J. (2014) · Journal of Nutritional Disorders & Therapy · doi:10.4172/2161-0509.1000142 · Cited by 18 · see citing works
An appraisal of folates as key factors in cognition and ageing-related diseases
Craenen, K., Verslegers, M., Baatout, S., & Benotmane, M. A. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1549017 · Cited by 18 · see citing works
Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells
Tang, Y.-S., Khan, R. A., Xiao, S., Hansen, D. K., Stabler, S. P., Kusumanchi, P., Jayaram, H. N., & Antony, A. C. (2017) · Journal of Nutrition · doi:10.3945/jn.116.241364 · Cited by 15 · see citing works
Dietary Intake and Biomarkers of Folate and Cobalamin Status in Norwegian Preschool Children: The FINS-KIDS Study
Solvik, B. S., Strand, T. A., Kvestad, I., Markhus, M. W., Ueland, P. M., McCann, A., & Øyen, J. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa111 · Cited by 16 · see citing works
Self-citation
Nutrition and Brain Development in Early Life
Prado, E. L., & Dewey, K. G. (2015) · Apple Academic Press eBooks · doi:10.1201/b18040-6 · Cited by 19 · see citing works
Prevalence and Predictors of Vitamin B12 Deficiency in Children with Severe Acute Malnutrition, and its Association with Development
Atiq, A., Shah, D., Sharma, S., Meena, R. K., Kapoor, S., & Gupta, P. (2023) · The Indian Journal of Pediatrics · doi:10.1007/s12098-023-04909-x · Cited by 15 · see citing works
Approaches to improving micronutrient status assessment at the population level
Lamers, Y. (2019) · Proceedings of The Nutrition Society · doi:10.1017/s0029665118002781 · Cited by 15 · see citing works
High-throughput analysis of total homocysteine and methylmalonic acid with the efficiency to separate succinic acid in serum and urine via liquid chromatography tandem mass spectrometry
Ma, X., Zou, Y., Tang, Y., Wang, D., Zhou, W., Yu, S., & Qiu, L. (2022) · Journal of Chromatography B · doi:10.1016/j.jchromb.2022.123135 · Cited by 15 · see citing works
Vitamin B12, Folate, and Cognition in 6- to 9-Year-Olds: A Randomized Controlled Trial
Kvestad, I., Taneja, S., Upadhyay, R. P., Hysing, M., Bhandari, N., & Strand, T. A. (2020) · PEDIATRICS · doi:10.1542/peds.2019-2316 · Cited by 16 · see citing works
Self-citation
Simultaneous detection of five one-carbon metabolites in plasma using stable isotope dilution liquid chromatography tandem mass spectrometry
Adaikalakoteswari, A., Webster, C., Goljan, I., & Saravanan, P. (2016) · Journal of Chromatography B · doi:10.1016/j.jchromb.2016.01.026 · Cited by 14 · see citing works
The effect of vitamin B12-supplementation on actigraphy measured sleep pattern; a randomized control trial
Hysing, M., Strand, T. A., Chandyo, R. K., Ulak, M., Ranjitkar, S., Schwinger, C., Shrestha, M., & Kvestad, I. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.11.040 · Cited by 14 · see citing works
Self-citation
Nutrient Inadequacy in Korean Young Adults with Depression: A Case Control Study
Yoon, S.-I., Moon, H.-R., Lee, S. R., Zhang, J., Lee, S., & Cho, J. A. (2023) · Nutrients · doi:10.3390/nu15092195 · Cited by 14 · see citing works
Ernährungsarmut bei Kindern – Ursachen, Folgen, COVID-19
Biesalski, H. K. (2021) · Aktuelle Ernährungsmedizin · doi:10.1055/a-1553-3202 · Cited by 14 · see citing works
Importância da vitamina B12 para a função neurológica e cognitiva: da gestação à infância
Zanella, P. B., & Garzone, E. O. C. (2021) · Revista de Atenção à Saúde · doi:10.13037/ras.vol19n69.7841 · Cited by 13 · see citing works
Association of development quotient with nutritional status of vitamins B6, B12, and folate in 6–59-month-old children: Results from the Brazilian National Survey on Child Nutrition (ENANI-2019)
de Freitas-Costa, N. C., Andrade, P. G., Normando, P., Salvatte, K., Raymundo, C. E., de Castro, I. R. R., Lacerda, E. M. D. A., Farias, D. R., & Kac, G. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.04.026 · Cited by 14 · see citing works
Genetic and environmental factors associated with vitamin B12status in Amazonian children
Cobayashi, F., Tomita, L. Y., Augusto, R. A., D’Almeida, V., & Cardoso, M. A. (2015) · Public Health Nutrition · doi:10.1017/s1368980014003061 · Cited by 11 · see citing works
Prevalence of specific micronutrient deficiencies in urban school going children of India aged between 6 and 16 years: study protocol for a multicentric cross-sectional study
Awasthi, S., Kumar, D., Singh, S., Dixit, S., Agarwal, G. G., & Mahdi, A. A. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-046783 · Cited by 12 · see citing works
Three-month B vitamin supplementation in pre-school children affects folate status and homocysteine, but not cognitive performance
Rauh-Pfeiffer, A., Handel, U., Demmelmair, H., Peißner, W., Niesser, M., Moretti, D., Martens, V. E. G., Wiseman, S. A., Weichert, J., Heene, M., et al. (2014) · European Journal of Nutrition · doi:10.1007/s00394-013-0647-y · Cited by 12 · see citing works
Vitamin B12deficiency in Indian infants and children
Goraya, J. S. (2020) · Paediatrics and International Child Health · doi:10.1080/20469047.2020.1741172 · Cited by 13 · see citing works
High Serum Folate Concentration, Vitamin B12 Deficiency, and Anthropometric Nutritional Status in Brazilian Children Aged 6–59 Months: Data from the Brazilian National Survey of Child Nutrition
Salvatte, K., Farias, D. R., Normando, P., Berti, T. L., de Castro, I. R. R., & Kac, G. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.05.020 · Cited by 11 · see citing works
Serum cobalamin in children with moderate acute malnutrition in Burkina Faso: Secondary analysis of a randomized trial
Friis, H., Cichon, B., Fabiansen, C., Iuel‐Brockdorff, A., Yaméogo, C. W., Ritz, C., Frikke‐Schmidt, R., Briend, A., Michaelsen, K. F., Christensen, V. B., et al. (2022) · PLoS Medicine · doi:10.1371/journal.pmed.1003943 · Cited by 10 · see citing works
Profile of Folate in Breast Milk from Chinese Women over 1–400 Days Postpartum
Su, Y., Mao, Y., Tian, F., Cai, X., Chen, R., Li, N., Qian, C., Li, X., Zhao, Y., & Wang, Y. (2022) · Nutrients · doi:10.3390/nu14142962 · Cited by 9 · see citing works
Vitamin B-12 Supplementation during Pregnancy and Early Lactation Does Not Affect Neurophysiologic Outcomes in Children Aged 6 Years
Srinivasan, K., Thomas, S., Anand, S., Jayachandra, M., Thomas, T. S., Strand, T. A., Kurpad, A. V., & Duggan, C. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa123 · Cited by 9 · see citing works
Self-citation
Simultaneous estimation of total homocysteine and methylmalonic-acid using LC-MS/MS: Clinical application in adult and pediatric
Mishra, A., Bisen, A. C., Kumar, P., Rathore, A., Verma, S. K., Sanap, S. N., Kumar, M., Godbole, M. M., & Bhatta, R. S. (2022) · Analytical Biochemistry · doi:10.1016/j.ab.2022.114907 · Cited by 9 · see citing works
Vitamins B 9 and B 12 in children with attention deficit hyperactivity disorder (ADHD)
Razavinia, F., Ebrahimian, A., Siahkal, S. F., Ghazinezhad, N., & Abedi, P. (2024) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000809 · Cited by 8 · see citing works
Epidemiology and Neurodevelopmental Correlates of Cobalamin Deficiency in Hospitalized North Indian Infants
Agarwal, N., & Chandrakanta, C. (2016) · Journal of Pediatric Neurology and Medicine · doi:10.4172/2472-100x.1000103 · Cited by 8 · see citing works
Vitamin B12 supplementation for growth, development, and cognition in children
Leal, C. G., Molina, X. E. P., Venkatramanan, S., Williams, J. L., Kuriyan, R., Crider, K. S., & Finkelstein, J. L. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015264 · Cited by 7 · see citing works
Vitamin B 12 status in infancy and the effect of a vitamin B 12 injection in infants with subclinical vitamin B 12 deficiency: study protocol for a register-based randomised controlled trial
Bakken, K. S., Kvestad, I., Bjørkevoll, S. M. G., Solvik, B. S., Kaldenbach, S., McCann, A., Holten-Andersen, M., Ersvær, E., Konijnenberg, C., & Strand, T. A. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-069102 · Cited by 7 · see citing works
Self-citation
One-Carbon Metabolism in Nepalese Infant–Mother Pairs and Child Cognition at 5 Years Old
Kvestad, I., McCann, A., Chandyo, R. K., Giil, L. M., Shrestha, M., Ulak, M., Hysing, M., Ueland, P. M., & Strand, T. A. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa403 · Cited by 7 · see citing works
Self-citation
The association between folic acid supplementation, maternal folate during pregnancy and intelligence development in infants: a prospective cohort study
Wang, S., Wei, J., Wang, D., Li, H., Pan, D., Fu, L., Yang, J., & Sun, G. (2021) · Food Science and Human Wellness · doi:10.1016/j.fshw.2021.02.009 · Cited by 7 · see citing works
Prevalence of serum cobalamin and folate deficiency among children aged 6–59 months: A hospital-based cross-sectional study from Northern India
Gupta, S., Haldar, P., Singh, A., Malhotra, S., & Kant, S. (2022) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_1137_21 · Cited by 7 · see citing works
Behavioral profile of vitamin B12 deficiency: A reflection of impaired brain development, neuronal stress and altered neuroplasticity
Pourié, G., Guéant, J., & Quadros, E. V. (2022) · Vitamins and hormones · doi:10.1016/bs.vh.2022.02.002 · Cited by 7 · see citing works
Urinary Metabolomics Identified Metabolic Perturbations Associated with Gutka, a Smokeless Form of Tobacco
Jorvekar, S. B., Jala, A., Rai, A., Jangili, S., Adla, D., Borkar, G. M., Das, A., Kakati, K., Das, K., Sarma, A., et al. (2023) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.2c00401 · Cited by 6 · see citing works
Efficacy and Safety of Vitamin B12 Fortification
Allen, L. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-802861-2.00026-2 · Cited by 6 · see citing works
Protocol of the Nutritional, Psychosocial, and Environmental Determinants of Neurodevelopment and Child Mental Health (COINCIDE) study
Lobo, E., Deepa, R., Mandal, S., Menon, J. S., Roy, A., Dixit, S., Gupta, R., Swaminathan, S., Thankachan, P., Bhavnani, S., et al. (2024) · Wellcome Open Research · doi:10.12688/wellcomeopenres.22817.1 · Cited by 5 · see citing works
Plasma vitamin B12 concentration is positively associated with cognitive development in healthy Danish 3-year-old children: the SKOT cohort studies
Larnkjær, A., Christensen, S. H., Lind, M. V., Michaelsen, K. F., & Mølgaard, C. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521004888 · Cited by 5 · see citing works
Diagnosing Deep Roots of Development: Genetic, Disease and Environmental FactorsPreprint
Fedderke, J. (2014) · RePEc: Research Papers in Economics · Cited by 5 · see citing works
Vitamin B12 supplementation for growth, development, and cognition in children
Larvie, D. Y., Leal, C. G., Venkatramanan, S., Molina, X. E. P., Steel, L. B., Kuriyan, R., & Finkelstein, J. L. (2026) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015264.pub2 · Cited by 4 · see citing works
Effects of maternal B12 supplementation on neurophysiological outcomes in children: a study protocol for an extended follow-up from a placebo randomised control trial in Bangalore, India
Anand, S., Thomas, S., Jayachandra, M., Thomas, T. S., Strand, T. A., Kurpad, A. V., Duggan, C., & Srinivasan, K. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-024426 · Cited by 4 · see citing works
Self-citation
Structural and Functional Brain Changes Associated with Vitamin B12 Deficiency using Magnetic Resonance Imaging: A Systematic Review and Meta-analysis
Alghamdi, A. (2022) · Current Medical Imaging Formerly Current Medical Imaging Reviews · doi:10.2174/1573405618666220516113758 · Cited by 4 · see citing works
Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age
Gatica‐Domínguez, G., Rothenberg, S. J., Torres‐Sánchez, L., Schnaas, M. D. L., Schmidt, R. J., & López‐Carrillo, L. (2018) · Salud Pública de México · doi:10.21149/8581 · Cited by 5 · see citing works
Evaluation of Neurodevelopmental Screening Test Scores in Children with Vitamin B12 Deficiency
Tanç, C., & Yıldız, İ. (2023) · Neuropediatrics · doi:10.1055/s-0043-1777125 · Cited by 4 · see citing works
Maternal and infant vitamin B12 status and development
Smith, A. D. (2018) · Pediatric Research · doi:10.1038/s41390-018-0110-0 · Cited by 3 · see citing works
Vegetarianism and Other Restricted Diets
Antony, A. C. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139023993.014 · Cited by 3 · see citing works
Relationships between Vitamin B12, Folate Levels and Clinical Features in Attention Deficit Hyperactivity Disorder and Attention Deficit Hyperactivity Disorder-Not Otherwise Specified
Öztürk, Y., Topal, Z., Demir, N., & Tufan, A. (2020) · Journal of Pediatric Research · doi:10.4274/jpr.galenos.2019.45822 · Cited by 4 · see citing works
Cross-cultural measurement invariance of a developmental assessment tool in a small-scale intervention study
Doennecke, N., Brandenburg, J., & Mähler, C. (2023) · Infant Behavior and Development · doi:10.1016/j.infbeh.2023.101888 · Cited by 2 · see citing works
Solving the Problem of Nutritional Deficiencies in Children
Li, J., & Wang, S. (2025) · Springer eBooks · doi:10.1007/978-981-96-8512-7_6 · Cited by 2 · see citing works
Signs and Symptoms of Vitamin B12 Deficiency and its Impacts on Student's Academic Performance
Mustafa, M. M., Atram, A. A. A., & Mousleh, M. M. (2014) · International Journal of Sciences: Basic and Applied Research · Cited by 2 · see citing works
Assessment of vitamin B 12 and folate status and their determinants in children aged 6–59 months with severe acute malnutrition admitted to a tertiary-care centre in North India
Verma, G. K., Chand, R., Yadav, R. K., Khan, I. A., Kumar, A., Kumar, R., & Bashar, M. (2024) · Paediatrics and International Child Health · doi:10.1080/20469047.2024.2407703 · Cited by 1 · see citing works
Impact of Key Nutrients on Brain and Executive Function Development in Infants and Toddlers: A Narrative Review
Franklyn, N., Kesavelu, D., Joji, P., Verma, R., Wadhwa, A., & Ray, C. (2022) · Journal of Food and Nutrition Sciences · doi:10.11648/j.jfns.20221001.14 · Cited by 1 · see citing works
Plasma Homocysteine level in Children under Treatment with Antiepileptic Drugs and its Relation to Intelligence Quotient
Al-maaty, M. A., Elmazahy, M., Emran, T. M., & El-khaleegy, H. (2020) · International Journal of Medical Arts · doi:10.21608/ijma.2020.16455.1029 · Cited by 1 · see citing works
Assessment of micronutrient status in pregnant Malawian women before and after treatment for moderate malnutrition
Glosz, C. M. (2016) · doi:10.15368/theses.2016.105 · Cited by 1 · see citing works
The effects of multi-nutrient fortified dairy-based formulas on growth, anaemia, and micronutrient status in Nigerian late preterm infants and moderately malnourished toddlers
Owolabi, A. J. (2023) · doi:10.18174/589830 · Cited by 1 · see citing works
Impacto da dieta cetogênica nas características oxidativas, físicas e lipídicas de lipoproteínas de crianças e adolescentes com epilepsia refratária
de Lima, P. A. (2014) · doi:10.11606/d.89.2014.tde-19092014-090404
The association of prenatal folate and vitamin B12 levels with postnatal neurodevelopment varies by maternal MTHFR 677C>T genotype
Gatica‐Domínguez, G., Rothenberg, S. J., Torres‐Sánchez, L., Schnaas, L., Stein, A. D., Schmidt, R. J., & López‐Carrillo, L. (2019) · International Journal of Behavioral Development · doi:10.1177/0165025419853379
Developmental Disabilities
Duncan, B., Andrews, J., Pottinger, H. L., & Meaney, F. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-43739-2_24
The Influence of the B Vitamins and Choline on the Developing Brain
(2016) · CRC Press eBooks · doi:10.1201/9781315372402-6
Comparison of the low-dose oral therapy results with literature and parenteral therapy in children with vitamin B12 deficiency
Sarbay, H., & Akin, M. (2022) · International Journal of Contemporary Pediatrics · doi:10.18203/2349-3291.ijcp20221064

Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age Strand TA, Taneja S, Ueland PM, Refsum H, Bahl R, Schneede J, Sommerfelt H og Bhandari N
Henriksen, C. (2013) · Norsk tidsskrift for ernæring · doi:10.18261/ntfe.11.1.8
Higher Maternal Plasma Folate but Not Vitamin B-12 Concentrations during Pregnancy Are Associated with Better Cognitive Function Scores in 9- to 10- Year-Old Children in South India
Veena, S. R., Krishnaveni, G. V., Srinivasan, K., Wills, A. K., Muthayya, S., Kurpad, A. V., Yajnik, C. S., & Fall, C. H. D. (2010) · Journal of Nutrition · doi:10.3945/jn.109.118075 · Cited by 170 · see citing works
Cobalamin and Folate Status among Breastfed Infants in Bhaktapur, Nepal
Chandyo, R., Ulak, M., Kvestad, I., Hysing, M., Shrestha, M., Ranjitkar, S., Ulvik, A., Ueland, P. M., Shrestha, L., & Strand, T. A. (2018) · Nutrients · doi:10.3390/nu10050639 · Cited by 22 · see citing works
Self-citation
Cobalamin and folate status in infants and young children in a low-to-middle income community in India
Taneja, S., Bhandari, N., Strand, T. A., Sommerfelt, H., Refsum, H., Ueland, P. M., Schneede, J., Bahl, R., & Bhan, M. K. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1302 · Cited by 132 · see citing works
Self-citation
Child dietary intake of folate and vitamin B12 and their neurodevelopment at 24 and 30 months of age
Gatica‐Domínguez, G., Rothenberg, S. J., Torres‐Sánchez, L., Schnaas, M. D. L., Schmidt, R. J., & López‐Carrillo, L. (2018) · Salud Pública de México · doi:10.21149/8581 · Cited by 5 · see citing works

Authors: Strand, T. A., Taneja, S., Ueland, P. M., Refsum, H., Bahl, R., Schneede, J., Sommerfelt, H., & Bhandari, N.
Affiliations: University of Bergen (NO)
ORCID: Strand, Tor A
Taneja, Sunita
Ueland, Per M
Refsum, Helga
Bahl, Rajiv
Sommerfelt, Halvor
Bhandari, Nita
Venue: The American Journal of Clinical Nutrition
Publisher: Elsevier BV
Published: 2013-02
Volume: 97
Issue: 2
Pages: 310-317
ISSN: 0002-9165 (ISSN-L)
DOI: 10.3945/ajcn.111.032268
OpenAlex: W2112708641
Cited by: 108
References: 38
Citations by year: 2026: 2 · 2025: 2 · 2024: 5 · 2023: 13 · 2022: 14 · 2021: 9 · 2020: 8 · 2019: 10 · 2018: 9 · 2017: 10 · 2016: 10 · 2015: 4 · 2014: 10 · 2013: 2
FWCI: 7.09
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3671 d)
Locations: American Journal of Clinical Nutrition (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Rheumatology › Folate and B Vitamins Research
Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
Keywords: vitamin B12, folic acid, homocysteine, methylmalonic acid, cognitive development, infant cognitive development, micronutrient deficiency, plasma biomarkers, psychomotor development, North Indian children
MeSH terms: Child Development, Developmental Disabilities, Cognition Disorders, Female, Folic Acid, Folic Acid Deficiency, Homocysteine, Humans, India, Infant, Male, Methylmalonic Acid, Nutritional Status, Psychomotor Performance, Vitamin B 12, Vitamin B 12 Deficiency, Cohort Studies, Biomarkers, Prevalence, Neurogenesis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Cobalamin and folate status predicts mental development scores in North Indian children 12–18 mo of age

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks