Dairy fat intake is associated with glucose tolerance, hepatic and systemic insulin sensitivity, and liver fat but not β-cell function in humans
Open accessAbstract
Background Plasma phospholipid concentrations of trans-palmitoleic acid (trans-16:1n-7), a biomarker of dairy fat intake, are inversely associated with incident type 2 diabetes in 2 US cohorts.Objective The objective was to investigate whether the intake of trans-16:1n-7 in particular, or dairy fat in general, is associated with glucose tolerance and key factors determining glucose tolerance.Design A cross-sectional investigation was undertaken in 17 men and women with nonalcoholic fatty liver disease and 15 body mass index (BMI)- and age-matched controls. The concentrations of trans-16:1n-7 and 2 other biomarkers of dairy fat intake, 15:0 and 17:0, were measured in plasma phospholipids and free fatty acids (FFAs). Liver fat was estimated by computed tomography-derived liver-spleen ratio. Intravenous-glucose-tolerance tests and oral-glucose-tolerance test (OGTT) and hyperinsulinemic-euglycemic clamps were performed to assess β-cell function and hepatic and systemic insulin sensitivity.Results In multivariate analyses adjusted for age, sex, and BMI, phospholipid 17:0, phospholipid trans-16:1n-7, FFA 15:0, and FFA 17:0 were inversely associated with fasting plasma glucose, the area under the curve for glucose during an OGTT, and liver fat. Phospholipid trans-16:1n-7 was also positively associated with hepatic and systemic insulin sensitivity. None of the biomarkers were associated with β-cell function. The associations between dairy fat intake and glucose tolerance were attenuated by adjusting for insulin sensitivity or liver fat, but strengthened by adjusting for β-cell function.Conclusion Although we cannot rule out reverse causation, these data support the hypothesis that dairy fat improves glucose tolerance, possibly through a mechanism involving improved hepatic and systemic insulin sensitivity and reduced liver fat.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In cohorts utilizing objective blood biomarkers, greater dairy fat consumption is associated with lower incidence of diabetes and CHD, with mixed findings for stroke.
“In cohorts utilizing objective blood biomarkers, greater dairy fat consumption is associated with lower incidence of diabetes59-61, 242, 243 and CHD,39, 244, 245 with mixed findings for stroke.246”
From Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review (2016) · cites this paper as [243]
Cites
A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189 · see citing works
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423 · see citing works
Diagnosis and Classification of Diabetes Mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc11-s062 · Cited by 14,019 · see citing works
Design and validation of a histological scoring system for nonalcoholic fatty liver disease†
Kleiner, D. E., Brunt, E. M., Van Natta, M., Behling, C., Contos, M. J., Cummings, O. W., Ferrell, L. D., Liu, Y., Torbenson, M. S., Unalp‐Arida, A., et al. (2005) · Hepatology · doi:10.1002/hep.20701 · Cited by 10,791 · see citing works
Self-citationAntihyperlipidemic and Biochemical Activities of Mcy Protein in Streptozotocin Induced Diabetic Rats
Marella, S., Maddirela, D. R., Badri, K. R., Kumar, M. V. J., & Chippada, A. R. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373954 · Cited by 5,938 · see citing works
Diagnosis and Classification of diabetes mellitus
Rossi, G. (2014) · Diapedia.org eBooks · doi:10.14496/dia..20 · Cited by 3,212 · see citing works
Direct transesterification of all classes of lipids in a one-step reaction.
Lepage, G., & ROY, C. C. (1986) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38861-1 · Cited by 2,385 · see citing works
Hodson, L., Skeaff, C. M., & Fielding, B. A. (2008) · Progress in Lipid Research · doi:10.1016/j.plipres.2008.03.003 · Cited by 1,315 · see citing works
Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism
Cao, H.-M., Gerhold, K., Mayers, J. R., Wiest, M., Watkins, S., & Hotamışlıgil, G. S. (2008) · Cell · doi:10.1016/j.cell.2008.07.048 · Cited by 1,142 · see citing works
Salvini, S., Hunter, D. J., SAMPSON, L., Stampfer, M. J., Colditz, G. A., ROSNER, B. A., & Willett, W. C. (1989) · International Journal of Epidemiology · doi:10.1093/ije/18.4.858 · Cited by 1,038 · see citing works
Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis
Wolfe, R. R., & Chinkes, D. L. (2004) · Medical Entomology and Zoology · Cited by 497 · see citing works
Maeda, K., Cao, H., Kono, K., Görgün, C. Z., Furuhashi, M., Uysal, K. T., Cao, Q., Atsumi, G., Malone, H., Krishnan, B. S., et al. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2004.12.008 · Cited by 479 · see citing works
Kelley, D. E., McKolanis, T. M., Hegazi, R. A. F., Kuller, L. H., & Kalhan, S. C. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00117.2003 · Cited by 426 · see citing works
Kratz, M., Baars, T., & Guyenet, S. (2013) · European Journal of Nutrition · doi:10.1007/s00394-012-0418-1 · Cited by 422 · see citing works
Self-citationMozaffarian, D., Cao, H., King, I. B., Lemaitre, R. N., Song, X., Siscovick, D. S., & Hotamisligil, G. S. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-153-12-201012210-00005 · Cited by 363 · see citing works
Self-citationFatty Infiltration of the Liver
Longo, R., RICC, C., Masutti, F., VIDIMARI, R., CROC, L. S., Bercich, L., Tiribelli, C., & Palma, L. D. (1993) · Investigative Radiology · doi:10.1097/00004424-199304000-00006 · Cited by 272 · see citing works
Mozaffarian, D., de Oliveira Otto, M. C., Lemaitre, R. N., Fretts, A. M., Hotamisligil, G., Tsai, M. Y., Siscovick, D. S., & Nettleton, J. A. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.045468 · Cited by 270 · see citing works
Evaluation of a biological marker of dairy fat intake
Wolk, A., Vessby, B. O., Ljung, H., & Barrefors, P. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.2.291 · Cited by 210 · see citing works
Plasma and erythrocyte biomarkers of dairy fat intake and risk of ischemic heart disease
Sun, Q., Ma, J., Campos, H., & Hu, F. B. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.4.929 · Cited by 171 · see citing works
Quantitative determination of plasma free fatty acids and triglycerides by thin-layer chromatography
Schlierf, G., & Wood, P. D. (1965) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39001-5 · Cited by 102 · see citing works
Phytanic acid—an overlooked bioactive fatty acid in dairy fat?
Hellgren, L. I. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05254.x · Cited by 86 · see citing works
Yarasheski, K. E., Cade, W. T., Overton, E. T., Mondy, K. E., Hubert, S., Laciny, E., Bopp, C., Lassa‐Claxton, S., & Reeds, D. N. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00468.2010 · Cited by 48 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Mozaffarian, D. (2016) · Circulation · doi:10.1161/circulationaha.115.018585 · Cited by 2,216 · see citing works
Flavonoids, Dairy Foods, and Cardiovascular and Metabolic Health
Mozaffarian, D., & Wu, J. H. Y. (2018) · Circulation Research · doi:10.1161/circresaha.117.309008 · Cited by 305 · see citing works
Venn-Watson, S. K., Lumpkin, R., & Dennis, E. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-64960-y · Cited by 254 · see citing works
Pimpin, L., Wu, J. H. Y., Haskelberg, H., Gobbo, L. C. D., & Mozaffarian, D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158118 · Cited by 212 · see citing works
Johnson, R. J., Sánchez‐Lozada, L. G., Andrews, P., & Lanaspa, M. A. (2017) · Advances in Nutrition · doi:10.3945/an.116.014654 · Cited by 162 · see citing works
Santaren, I. D., Watkins, S. M., Liese, A. D., Wagenknecht, L. E., Rewers, M., Haffner, S. M., Lorenzo, C., & Hanley, A. J. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.092544 · Cited by 142 · see citing works
Yakoob, M. Y., Shi, P., Willett, W. C., Rexrode, K. M., Campos, H., Orav, E. J., Hu, F. B., & Mozaffarian, D. (2016) · Circulation · doi:10.1161/circulationaha.115.018410 · Cited by 140 · see citing works
Milk fat: opportunities, challenges and innovation
Mohan, M. S., O’Callaghan, T. F., Kelly, P. M., & Hogan, S. A. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1778631 · Cited by 123 · see citing works
Meex, R. C. R., & Blaak, E. E. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900942 · Cited by 108 · see citing works
Dairy foods and positive impact on the consumer's health
Verruck, S., Balthazar, C. F., Rocha, R. S., Silva, R., Esmerino, E. A., Pimentel, T. C., Freitas, M. Q., Silva-Santos, M. C., da Cruz, A. G., & Prudêncio, E. S. (2019) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2019.03.002 · Cited by 96 · see citing works
The influence of dietary fatty acids on liver fat content and metabolism
Hodson, L., Rosqvist, F., & Parry, S. A. (2019) · Proceedings of The Nutrition Society · doi:10.1017/s0029665119000569 · Cited by 93 · see citing works
Feeney, E. L., Barron, R. E., Dible, V. A., Hamilton, Z., Power, Y., Tanner, L., Flynn, C., Bouchier, P., Beresford, T. P. J., Noronha, N., et al. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy146 · Cited by 92 · see citing works
Astrup, A. V., Geiker, N. R. W., & Magkos, F. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz069 · Cited by 91 · see citing works
Unger, A. L., Torres‐Gonzalez, M., & Kraft, J. (2019) · Nutrients · doi:10.3390/nu11092200 · Cited by 88 · see citing works
Yogurt and Diabetes: Overview of Recent Observational Studies
Salas‐Salvadó, J., Guasch‐Ferré, M., Díaz‐López, A., & Babió, N. (2017) · Journal of Nutrition · doi:10.3945/jn.117.248229 · Cited by 83 · see citing works
Venn-Watson, S. K., & Schork, N. J. (2023) · Nutrients · doi:10.3390/nu15214607 · Cited by 74 · see citing works
Tsompanaki, E., Thanapirom, K., Papatheodoridi, Μ., Parikh, P. M., de Lima, Y. C., & Tsochatzis, E. A. (2021) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2021.11.026 · Cited by 70 · see citing works
Guo, J., Givens, D. I., Astrup, A., Bakker, S. J. L., Goossens, G. H., Kratz, M., Marette, A., Pijl, H., & Soedamah‐Muthu, S. S. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz050 · Cited by 69 · see citing works
Self-citationRed meat, dairy, and insulin sensitivity: a randomized crossover intervention study
Turner, K., Keogh, J. B., & Clifton, P. M. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.104976 · Cited by 61 · see citing works
Turner, K., Keogh, J. B., & Clifton, P. M. (2014) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2014.07.013 · Cited by 59 · see citing works
Astrup, A. V., Bradley, B. H. R., Brenna, J. T., Delplanque, B., Ferry, M., & Torres‐Gonzalez, M. (2016) · Nutrients · doi:10.3390/nu8080463 · Cited by 53 · see citing works
Hess, J., Jonnalagadda, S. S., & Slavin, J. L. (2015) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12183 · Cited by 52 · see citing works
Yogurt consumption and abdominal obesity reversion in the PREDIMED study
Santiago, S., Sayón-Orea, C., Babió, N., Ruiz‐Canela, M., Martí, A., Corella, D., Estruch, R., Fitó, M., Arós, F., Ros, E., et al. (2015) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2015.11.012 · Cited by 50 · see citing works
Cardiometabolic health benefits of dairy-milk polar lipids
Bruno, R. S., Pokala, A., Torres‐Gonzalez, M., & Blesso, C. N. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab085 · Cited by 48 · see citing works
Park, S., Ahn, J., Kim, N.-S., & Lee, B.-K. (2016) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2016.1252318 · Cited by 47 · see citing works
Determinants of ectopic liver fat in metabolic disease
Bosy‐Westphal, A., Braun, W., Albrecht, V., & Müller, M. J. (2018) · European Journal of Clinical Nutrition · doi:10.1038/s41430-018-0323-7 · Cited by 47 · see citing works
Silva, M. S. D., Julien, P., Bilodeau, J., Barbier, O., & Rudkowska, I. (2017) · Lipids · doi:10.1007/s11745-017-4243-4 · Cited by 45 · see citing works
Natural Rumen‐Derived trans Fatty Acids Are Associated with Metabolic Markers of Cardiac Health
Silva, M. S. D., Julien, P., Përusse, L., Vohl, M., & Rudkowska, I. (2015) · Lipids · doi:10.1007/s11745-015-4055-3 · Cited by 45 · see citing works
Mozaffarian, D. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehv595 · Cited by 40 · see citing works
Maki, K. C., Nieman, K. M., Schild, A. L., Kaden, V. N., Lawless, A. L., Kelley, K., & Rains, T. M. (2015) · Journal of Nutrition · doi:10.3945/jn.114.204503 · Cited by 40 · see citing works
Sualeheen, A., Tan, S., Georgousopoulou, E. N., Daly, R. M., Tierney, A. C., Roberts, S. K., & George, E. S. (2024) · Nutrition Bulletin · doi:10.1111/nbu.12707 · Cited by 37 · see citing works
Poudyal, H., & Brown, L. (2015) · Progress in Lipid Research · doi:10.1016/j.plipres.2015.07.002 · Cited by 34 · see citing works
Guillocheau, É., Legrand, P., & Rioux, V. (2019) · Biochimie · doi:10.1016/j.biochi.2019.12.004 · Cited by 33 · see citing works
Mitri, J., Tomah, S., Mottalib, A., Salsberg, V., Ashrafzadeh, S., POBER, D. M., Eldib, A. H., Tasabehji, M. W., & Hamdy, O. (2020) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa138 · Cited by 32 · see citing works
Role of Mediterranean diet in prevention and management of type 2 diabetes
Hidayat, K., & Bimin, S. (2014) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20141358 · Cited by 32 · see citing works
Dairy intake and type 2 diabetes risk factors: A narrative review
Mitri, J., Yusof, B. N. M., Maryniuk, M. D., Schrager, C., Hamdy, O., & Salsberg, V. (2019) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2019.07.064 · Cited by 29 · see citing works
Pranger, I. G., Muskiet, F. A. J., Kema, I. P., Singh‐Povel, C. M., & Bakker, S. J. L. (2019) · Nutrients · doi:10.3390/nu11051099 · Cited by 28 · see citing works
Double bond configuration of palmitoleate is critical for atheroprotection
Çimen, İ., Yıldırım, Z., Atici, A. E., Yıldırım, A., Tufanlı, Ö., Onat, U. İ., Nguyen, U. T., Watkins, S. M., Weber, C., & Erbay, E. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.08.004 · Cited by 26 · see citing works
Charatcharoenwitthaya, P., Tansakul, E., Chaiyasoot, K., Bandidniyamanon, W., & Charatcharoenwitthaya, N. (2021) · Nutrients · doi:10.3390/nu13124438 · Cited by 25 · see citing works
Dai, W., Liu, H., Zhang, T., Chang, Q., Zhao, Y., Guo, C., & Xia, Y. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1119118 · Cited by 24 · see citing works
Guillocheau, É., Garcia, C., Drouin, G., Richard, L., Catheline, D., Legrand, P., & Rioux, V. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.09.010 · Cited by 24 · see citing works
Silva, M. S. D., Julien, P., Couture, P., Lemieux, S., Vohl, M., & Rudkowska, I. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2014-0154 · Cited by 22 · see citing works
Parodi, P. W. (2016) · Medical Hypotheses · doi:10.1016/j.mehy.2015.12.028 · Cited by 22 · see citing works
Eslami, O., & Shidfar, F. (2018) · Nutrition (Burbank, Los Angeles County, Calif.) · doi:10.1016/j.nut.2018.03.047 · Cited by 18 · see citing works
Eelderink, C., Rietsema, S., van Vliet, I. M. Y., Loef, L. C., Boer, T. S., Koehorst, M., Nolte, I. M., Westerhuis, R., Singh‐Povel, C. M., Geurts, J. M. W., et al. (2019) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqz017 · Cited by 22 · see citing works
Venn-Watson, S. K. (2024) · Metabolites · doi:10.3390/metabo14070355 · Cited by 20 · see citing works
Silva, M. S. D., Bilodeau, J., Larose, J., Greffard, K., Julien, P., Barbier, O., & Rudkowska, I. (2017) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2017.09.016 · Cited by 20 · see citing works
Tremblay, B. L., & Rudkowska, I. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nuw066 · Cited by 20 · see citing works
Sandby, K., Magkos, F., Chabanova, E., Petersen, E. T., Krarup, T., Bertram, H. C., Kristiansen, K., & Geiker, N. R. W. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.12.018 · Cited by 19 · see citing works
Fridén, M., Rosqvist, F., Kullberg, J., Ahlström, H. K., Lind, L., & Risérus, U. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab221 · Cited by 17 · see citing works
Sellem, L., Jackson, K. G., Paper, L., Givens, I. D., & Lovegrove, J. A. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522000289 · Cited by 16 · see citing works
Arenaza, L., Medrano, M., Osés, M., Huybrechts, I., López, I. D., Henriksson, H., & Labayen, I. (2019) · British Journal Of Nutrition · doi:10.1017/s0007114519000436 · Cited by 16 · see citing works
Eekelen, E. W.-V., Beulens, J. W. J., Geelen, A., Schrauwen‐Hinderling, V. B., Lamb, H. J., Roos, A., Rosendaal, F. R., & de Mutsert, R. (2018) · Journal of Nutrition · doi:10.1093/jn/nxy313 · Cited by 16 · see citing works
Kummer, K., Jensen, P. N., Kratz, M., Lemaître, R. N., Howard, B. V., Cole, S. A., & Fretts, A. M. (2019) · Journal of Nutrition · doi:10.1093/jn/nxz058 · Cited by 16 · see citing works
Self-citationGuo, J., Givens, D. I., & Heitmann, B. L. (2022) · PLoS ONE · doi:10.1371/journal.pone.0271168 · Cited by 14 · see citing works
Mitri, J., Tomah, S., Furtado, J. D., Tasabehji, M. W., & Hamdy, O. (2021) · Nutrients · doi:10.3390/nu13041145 · Cited by 12 · see citing works
Bishop, C. A., Machate, T., Henkel, J., Schulze, M. B., Klaus, S., & Piepelow, K. (2023) · Nutrients · doi:10.3390/nu15092052 · Cited by 11 · see citing works
Metabolic effects of milk fatty acids: A literature review
Muñoz‐Alvarez, K. Y., Gutiérrez‐Aguilar, R., & Frigolet, M. E. (2024) · Nutrition Bulletin · doi:10.1111/nbu.12657 · Cited by 11 · see citing works
Guo, P., Zhu, H., Pan, H., Feng, R., Chen, Y., Wang, Y., Wang, X., Li, Y., Yang, L., Zhou, B., et al. (2019) · Journal of Diabetes · doi:10.1111/1753-0407.12921 · Cited by 10 · see citing works
Hegazy, M., Vidović, B. B., Abobakr, S., Zeljković, A., Stefanović, A., & Vekić, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311715 · Cited by 9 · see citing works
Cavali, J. B., Filho, J. V. D., Nunes, C. T., Ferreira, E., Pontuschka, R. B., Zanella, R., & de Souza, M. L. R. (2023) · Acta Scientiarum Animal Sciences · doi:10.4025/actascianimsci.v45i1.61186 · Cited by 9 · see citing works
Jiao, J., Kwan, S., Sabotta, C. M., Tanaka, H., Veillon, L. J., Warmoes, M. O., Lorenzi, P. L., Wang, Y., Wei, P., Hawk, E. T., et al. (2021) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-21-0183 · Cited by 9 · see citing works
Cavali, J. B., Marmentini, R. P., Filho, J. V. D., Pontuschka, R. B., & Schons, S. D. V. (2022) · Boletim do Instituto de Pesca · doi:10.20950/1678-2305/bip.2022.48.e700 · Cited by 9 · see citing works
Santaren, I. D., Bazinet, R. P., Liu, Z., Johnston, L., Sievenpiper, J. L., Giacca, A., Retnakaran, R. R., Harris, S. B., Zinman, B., & Hanley, A. J. (2019) · Lipids · doi:10.1002/lipd.12185 · Cited by 8 · see citing works
Lee, J. H., Lee, H. S., Jeon, S., Lee, J., & Kwon, Y. (2024) · Digestive and Liver Disease · doi:10.1016/j.dld.2024.01.200 · Cited by 8 · see citing works
We are what we eat: The role of lipids in metabolic diseases
Berná, G., López-Bermudo, L., Escudero‐López, B., & Martı́n, F. (2023) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2022.11.004 · Cited by 7 · see citing works
Martin, H. R., Martínez, S. S., Stebliankin, V., Tamargo, J. A., Campa, A. L., Narasimhan, G., Hernández, J., Rodriguez, J. A. B., Teeman, C. S., Johnson, A., et al. (2023) · Metabolites · doi:10.3390/metabo13020271 · Cited by 6 · see citing works
Xu, F., Huang, Y., Liu, C., Cai, X. D., Ji, Z., Sun, M., Ding, S., Gu, D., & Yang, Y. (2019) · Journal of Liquid Chromatography & Related Technologies · doi:10.1080/10826076.2019.1625373 · Cited by 5 · see citing works
Rocha, A. S. C. M., Baldi, S. C. V., de Souza, M. L. R., Rosa, B. L., Soares, E. C., Pontuschka, R. B., Filho, J. V. D., & Cavali, J. B. (2023) · Boletim do Instituto de Pesca · doi:10.20950/1678-2305/bip.2023.49.e793 · Cited by 5 · see citing works
Chen, Y., Sui, J., Yu, Y., Zhang, H., Wesselius, A., Shen, Y., Qin, Q., Sun, G., Wang, S., Wang, X., et al. (2025) · BMC Medicine · doi:10.1186/s12916-025-04554-5 · Cited by 4 · see citing works
Mohammadi, F., Beauparlant, C. J., Bianco, S., Droit, A., Bertrand, N., & Rudkowska, I. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400290 · Cited by 3 · see citing works
Guillocheau, É., Drouin, G., Catheline, D., Orione, C., Legrand, P., & Rioux, V. (2020) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201900409 · Cited by 3 · see citing works
Produits laitiers et risque cardio-métabolique
Lecerf, J. (2020) · Médecine des Maladies Métaboliques · doi:10.1016/j.mmm.2020.07.007 · Cited by 3 · see citing works
Guillocheau, É., Milard, M., Rioux, V., Bourlieu, C., & Michalski, M. (2020) · Springer eBooks · doi:10.1007/978-3-030-48686-0_10 · Cited by 3 · see citing works
Lipid Quality of Amazonian’s Native Fish, Overview and Market Outlook of Brazilian Fish Farming
Marmentini, R. P., Filho, J. V. D., dos Santos, R. B., Cortegano, C. A. A., & Cavali, J. B. (2024) · Revista Brasileira Multidisciplinar · doi:10.25061/2527-2675/rebram/2024.v27i1.1684 · Cited by 3 · see citing works
Unger, A. L., Jetton, T. L., & Kraft, J. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521004001 · Cited by 3 · see citing works
da Gama, M. A. S., Filho, H. G. B., Bizzo, H. R., & Antoniassi, R. (2017) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2017.107 · Cited by 3 · see citing works
How Much Fat Does One Need to Eat to Get a Fatty Liver? A Dietary View of NAFLD
Sasdelli, A. S., Barbanti, F. A., & Marchesini, G. (2016) · Springer eBooks · doi:10.1007/978-3-319-30361-1_8 · Cited by 2 · see citing works
Macro Components in Dairy and Their Effects on Inflammation Parameters
Silva, M. S. D., & Rudkowska, I. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809762-5.00022-x · Cited by 2 · see citing works
Tomah, S., Eldib, A. H., Tasabehji, M. W., Mitri, J., Salsberg, V., Al-Badri, M. R., Gardner, H. M., & Hamdy, O. (2020) · Nutrients · doi:10.3390/nu12061643 · Cited by 2 · see citing works
The Relation of Impaired Fasting Glucose and HDL-Cholesterol by Gender and Body Mass Index
Jin, S.-H. (2019) · Journal of Health Informatics and Statistics · doi:10.21032/jhis.2019.44.1.8 · Cited by 2 · see citing works
Lee, J.-H., Ryu, H. E., Han, T., Park, B., Heo, S., & Kwon, Y. (2025) · Endocrine · doi:10.1007/s12020-025-04200-3 · Cited by 1 · see citing works
Balanced diets are associated with a lower risk of type 2 diabetes than plant-based diets
Kang, B., Yin, X., Chen, D., Wang, Y., Lv, J., Zhou, J., Chen, X., Kou, X., Hang, X., Yang, Q., et al. (2024) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2024.111977 · Cited by 1 · see citing works
Beyond Saturated Fat: A Four‐Dimensional Framework for Understanding Milk Fat in Human Health
Liu, N., Duan, S., He, J., Feng, G., Deng, Z., & Li, J. (2026) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70595 · Cited by 1 · see citing works
Effect of consumption of Milk and Yoghurt on Lipid metabolism and Atherosclerosis in adult male rats
Halaby, M., Farag, M. H., Mahmoud, M. H., Badawy, I., Abd‐Rabou, N. S., & Mohammed, F. E.-Z. S. (2015) · Cited by 1 · see citing works
Santaren, I. D. (2014) · TSpace (University of Toronto)
Schmidt, K. A. (2020) · ResearchWorks at the University of Washington (University of Washington)
Hedayat, K. M., & Lapraz, J.-C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816908-7.00011-6
Khalil, N. A., Aly, S., Saad, M. A., & Sarbini, S. R. (2024) · Food Research · doi:10.26656/fr.2017.8(2).039
Dairy fat biomarkers and cardiometabolic health
Ohlsson, J. (2014) · Epsilon Archive for Student Projects (University of Southampton)
Kim, D. K., Rajan, P., Cuong, D. M., Yoon, T. H., Yang, S. H., Oyinloye, K. R., Go, G. M., & Cho, S. K. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107311
- Authors
- Kratz, M., Marcovina, S., Nelson, J. E., Yeh, M. M., Kowdley, K. V., Callahan, H. S., Song, X., Di, C., & Utzschneider, K. M.
- Affiliations
- Virginia Mason Medical Center (US)
- ORCID
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2014-06
- Volume
- 99
- Issue
- 6
- Pages
- 1385-1396
- ISSN
- 0002-9165 (ISSN-L)
- PMC
- PMC4021783
- OpenAlex
- W2120120974
- Cited by
- 95
- References
- 22
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 9 · 2023: 8 · 2022: 3 · 2021: 7 · 2020: 9 · 2019: 19 · 2018: 6 · 2017: 8 · 2016: 7 · 2015: 8 · 2014: 6
- FWCI
- 9.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (UL1TR000423, 5p41rr000954-34, UL1TR002319)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK 056341, K24DK002957, DK‐020579, P30DK056341, P30DK035816, P30DK017047, U01DK061728, T32DK007247)
- National Institute of Environmental Health Sciences (R21ES022332)
- National Center for Research Resources (RR-000954, UL1RR025014)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- trans-palmitoleic acid, glucose tolerance, insulin sensitivity, hepatic insulin sensitivity, liver fat, non-alcoholic fatty liver disease, beta-cell function, plasma phospholipids, free fatty acids, type 2 diabetes risk
- MeSH terms
- Insulin Secretion, Adult, Cross-Sectional Studies, Dairy Products, Dietary Fats, Fatty Acids, Fatty Acids, Monounsaturated, Female, Humans, Insulin, Insulin Resistance, Liver, Male, Middle Aged, Tomography, X-Ray Computed, Cohort Studies, Biomarkers, Case-Control Studies, Trans Fatty Acids, Lipid Metabolism, Insulin-Secreting Cells, Non-alcoholic Fatty Liver Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review