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Initiation of V(D)J recombination in vitro obeying the 12/23 rule

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The Homeodomain Region of Rag-1 Reveals the Parallel Mechanisms of Bacterial and V(D)J Recombination

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RAG1 Mediates Signal Sequence Recognition and Recruitment of RAG2 in V(D)J Recombination

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Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

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Identification of Two Catalytic Residues in RAG1 that Define a Single Active Site within the RAG1/RAG2 Protein Complex

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Drosophila Kelch Is an Oligomeric Ring Canal Actin Organizer

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Definition of a core region of RAG-2 that is functional in V(D)J recombination

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Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

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Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

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Hairpin Coding End Opening Is Mediated by RAG1 and RAG2 Proteins

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The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2

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DNA Hairpin Opening Mediated by the RAG1 and RAG2 Proteins

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V(D)J Recombination Signal Recognition

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The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis

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Antigen receptor gene rearrangement

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Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2

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A Zinc-binding Domain Involved in the Dimerization of RAG1

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RAG-2 Promotes Heptamer Occupancy by RAG-1 in the Assembly of a V(D)J Initiation Complex

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Identification of Kel1p, a Kelch Domain-containing Protein Involved in Cell Fusion and Morphology in Saccharomyces cerevisiae

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Omenn Syndrome: A Disorder of Rag1 and Rag2 Genes

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The RAG1/RAG2 Complex Constitutes a 3′ Flap Endonuclease

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Detection of RAG Protein-V(D)J Recombination Signal Interactions Near the Site of DNA Cleavage by UV Cross-Linking

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Footprint Analysis of the RAG Protein Recombination Signal Sequence Complex for V(D)J Type Recombination

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Functional Analysis of Coordinated Cleavage in V(D)J Recombination

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RAG1 and RAG2 Cooperate in Specific Binding to the Recombination Signal Sequence in Vitro

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Definition of a large region of RAG1 that is important for coimmunoprecipitation of RAG2

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The Effect of Me2+ Cofactors at the Initial Stages of V(D)J Recombination

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Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage

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In vitro V(D)J recombination: Signal joint formation

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V(D)J Recombination: Mechanisms of Initiation

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RAG1 Core and V(D)J Recombination Signal Sequences Were Derived from Transib Transposons

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Keep Your Fingers Off My DNA: Protein–Protein Interactions Mediated by C2H2 Zinc Finger Domains

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Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences

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Evolution of the RAG1-RAG2 locus: both proteins came from the same transposon

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The bounty of RAGs: recombination signal complexes and reaction outcomes

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The RAG proteins in V(D)J recombination: more than just a nuclease

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The Protein-Binding Potential of C2H2 Zinc Finger Domains

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A RAG-1/RAG-2 Tetramer Supports 12/23-Regulated Synapsis, Cleavage, and Transposition of V(D)J Recombination Signals

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Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombinationPreprint

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Mutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase

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Regulation of RAG1/RAG2‐mediated transposition by GTP and the C‐terminal region of RAG2

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Mutations in Conserved Regions of the Predicted RAG2 Kelch Repeats Block Initiation of V(D)J Recombination and Result in Primary Immunodeficiencies

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Identification of Two Topologically Independent Domains in RAG1 and Their Role in Macromolecular Interactions Relevant to V(D)J Recombination

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Identification of Basic Residues in RAG2 Critical for DNA Binding by the RAG1-RAG2 Complex

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Initial Stages of V(D)J Recombination: The Organization of RAG1/2 and RSS DNA in the Postcleavage Complex

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Cooperative recruitment of HMGB1 during V(D)J recombination through interactions with RAG1 and DNA

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Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1

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Impaired social recognition memory in recombination activating gene 1-deficient mice

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The Central Domain of Core RAG1 Preferentially Recognizes Single-stranded Recombination Signal Sequence Heptamer

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Overlapping Signals for Protein Degradation and Nuclear Localization Define a Role for Intrinsic RAG-2 Nuclear Uptake in Dividing Cells

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Cloning of shark RAG2 and characterization of the RAG1/RAG2 gene locus

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RAG1-mediated ubiquitylation of histone H3 is required for chromosomal V(D)J recombination

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RAG1 and RAG2 in V(D)J Recombination and Transposition

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The recombinase activating genes: architects of immune diversity during lymphocyte development

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Identification and Characterization of a Gain-of-Function RAG-1 Mutant

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The Mechanism of V(D)J Recombination

Little, A. J., Matthews, A. G. W., Oettinger, M. A., Roth, D. B., & Schatz, D. G. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397933-9.00002-3 · Cited by 25 · see citing works

Mapping and Quantitation of the Interaction between the Recombination Activating Gene Proteins RAG1 and RAG2

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Elucidating the domain architecture and functions of non-core RAG1: The capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding

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DNA Cleavage Activity of the V(D)J Recombination Protein RAG1 Is Autoregulated

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Recombinase activating gene enzymes of lymphocytes

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