Cutting Edge: Essential Role of Phospholipase C-γ2 in B Cell Development and Function

Cited by (156)

Items 101–156 of 156

  1. The mitochondrial sodium/calcium exchanger NCLX (Slc8b1) in B lymphocytes
    Scott M. Emrich, Ryan E. Yoast, Adam J. Fike, Kristen N Bricker, Ping Xin, Xuexin Zhang, Ziaur S. M. Rahman, Mohamed Trebak · 2022 · Cell Calcium
  2. PLCγ2: where bone and immune cells find their common ground
    Roberta Faccio, Viviana Cremasco · 2010 · Annals of the New York Academy of Sciences
  3. Btk and phospholipase Cγ2 can function independently during B cell development
    Kristina E. Halcomb, Cristina M. Contreras, Rochelle M. Hinman, Terry G. Coursey, Heather L. Wright, Anne B. Satterthwaite · 2007 · European Journal of Immunology
  4. Multitasking of Ig-α and Ig-β to Regulate B Cell Antigen Receptor Function
    Jürgen Wienands, Niklas Engels · 2001 · International Reviews of Immunology
  5. Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin
    Thomas L. Rothstein, Ben-Chang Guo · 2009 · Journal of Internal Medicine
  6. Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN- production
    Shinya Hidano, H. Sasanuma, K. Ohshima, Ken‐ichiro Seino, Lalit Kumar, Katsuhiko Hayashi, Minami Hikida, Tomohiro Kurosaki, Masaru Taniguchi, Raif S. Geha et al. · 2008 · International Immunology
  7. BCR signal through α4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation
    Inui, Seiji, Maeda, Kazuhiko, Hua, Ding Rong, Yamashita, Takeshi, Yamamoto, Hideyuki, Miyamoto, Eishichi, Aizawa, Shinichi, Sakaguchi, Nobuo · 2002 · International Immunology
  8. Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cγ
    Adrienne Halupa, Manprit Chohan, Natalie H. Stickle, Bryan K. Beattie, Barbara A. Miller, Dwayne L. Barber · 2005 · Experimental Cell Research
  9. Regulation of Phospholipase C‐γ2 Networks in B Lymphocytes
    Masaki Hikida, Tomohiro Kurosaki · 2005 · Advances in immunology
  10. PLCγ2 impacts microglia-related effectors revealing variants and pathways important in Alzheimer’s disease
    Li, Ke, Ran, Beibei, Wang, Yu, Liu, Lulu, Li, Weidong · 2022 · Frontiers in Cell and Developmental Biology
  11. Phospholipids: “Greasing the wheels” of humoral immunity
    Joseph W. Brewer · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  12. Phospholipase Cγ1 (PLCγ1) Controls Osteoclast Numbers via Colony-stimulating Factor 1 (CSF-1)-dependent Diacylglycerol/β-Catenin/CyclinD1 Pathway
    Zhengfeng Yang, Seokho Kim, Sahil Mahajan, Ali Zamani, Roberta Faccio · 2016 · Journal of Biological Chemistry
  13. Identification of genes involved in immune response of Atlantic salmon (Salmo salar) to IPN virus infection, using expressed sequence tag (EST) analysis
    Victoria Cepeda, Catalina Cofré, Ruth González, Simon A MacKenzie, Rodrigo Vidal · 2011 · Aquaculture
  14. Regulation of Phospholipase C-γ2 and Phosphoinositide 3-Kinase Pathways by Adaptor Proteins In B Lymphocytes
    Tomohiro Kurosaki, Takaharu Okada · 2001 · International Reviews of Immunology
  15. BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response
    Masayuki P. Yamamoto · 2004 · International Immunology
  16. Proximal B cell receptor signaling pathways
    Brian J. Skaggs, Marcus R. Clark · 2004 · Signal Transduction
  17. PKCη directs induction of IRF-4 expression and Ig κ gene rearrangement in pre-BCR signaling pathway
    Akihisa Oda, Tomohiro Ono, Mutsumi Yamamoto, Ryo Goitsuka, Daisuke Kitamura · 2008 · International Immunology
  18. Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications
    Tina Nguyen, Elissa K. Deenick, Stuart G. Tangye · 2021 · Expert Review of Clinical Immunology
  19. Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1
    Yongwei Zheng, Tamara L. Adams, Huiying Zhi, Mei Yu, Renren Wen, Peter J. Newman, Demin Wang, Debra K. Newman · 2015 · PLoS ONE
  20. Distinct Roles of Phosphoinositide-3 Kinase and Phospholipase Cγ2 in B-Cell Receptor-Mediated Signal Transduction
    Dai, Xuezhi, Chen, Yuhong, Schuman, James, Hua, Zichun, Adamson, John W., Wen, Renren, Wang, Demin · 2006 · Molecular and Cellular Biology
  21. Phospholipases in Health and Disease
    Yong Ryoul Yang, Hyun‐Jun Jang, Sung Ho Ryu, Pann‐Ghill Suh · 2014 · Springer eBooks
  22. Phospholipase Cγ2 Dosage Is Critical for B Cell Development in the Absence of Adaptor Protein BLNK
    Xu, Shengli, Huo, Jianxin, Chew, Weng-Keong, Hikida, Masaki, Kurosaki, Tomohiro, Lam, Kong-Peng · 2006 · The Journal of Immunology
  23. A hypomorphic IgH‐chain allele affects development of B‐cell subsets and favours receptor editing
    Sven Brenner, Diana Drewel, Thomas Steinbart, Florian J. Weisel, Eric Haertel, Sonja Pötzsch, Heike Welzel, Andreas Brandl, Philipp Yu, Geert C. Mudde et al. · 2011 · The EMBO Journal
  24. Phospholipase Cγ2 Is Essential for Experimental Models of Epidermolysis Bullosa Acquisita
    Kata P. Szilveszter, Simon Vikár, Ádám István Horváth, Zsuzsanna Helyes, Miklós Sárdy, Attila Mócsai · 2021 · Journal of Investigative Dermatology
  25. Neutrophil Phospholipase Cγ2 Drives Autoantibody‐Induced Arthritis Through the Generation of the Inflammatory Microenvironment
    Krisztina Futosi, Orsolya Kása, Kata P. Szilveszter, Attila Mócsai · 2021 · Arthritis & Rheumatology
  26. NF‐κB signaling in B‐1 cell development
    Gabriel Kristian Pedersen, Mónika Ádori, Gunilla B. Karlsson Hedestam · 2015 · Annals of the New York Academy of Sciences
  27. Re-distribution of phospholipase C gamma 2 in macrophage precursors is mediated by the actin cytoskeleton under the control of the Src kinases
    Marie-Therese Dearden-Badet, Guy Mouchiroud · 2005 · Cellular Signalling
  28. Phospholipase C-γ Contains Introns Shared by src Homology 2 Domains in Many Unrelated Proteins
    Charlene M Manning, Wendy R Mathews, Leah P Fico, Justin R. Thackeray · 2003 · Genetics
  29. Activation of Phospholipase C 2 by Tyrosine Phosphorylation
    Fatih Özdener, Carol Dangelmaier, Barrie Ashby, Satya P. Kunapuli · 2002
  30. Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma
    Miguel A. Hernandez‐Lara, Joshua Richard, Deepak A. Deshpande · 2024 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  31. Distinct Phospholipase C-γ-Dependent Signaling Pathways in the Drosophila Eye and Wing Are Revealed by a New small wing Allele
    Rishikesh Mankidy, Jeremy Hastings, Justin R. Thackeray · 2003 · Genetics
  32. Variations in the human phospholipase Cγ2 gene in patients with B-cell defects of unknown etiology
    D. Wang, E. C. Boylin, Y. Minegishi, R. Wen, Edvard C. I. Smith, J. Ihle, M. Conley · 2001 · Immunogenetics
  33. Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinase
    Lindsey R. Whyburn · 2003 · International Immunology
  34. Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice
    Hirotake Ichise, Taeko Ichise, Nobuaki Yoshida · 2016 · PLoS ONE
  35. BCR activation of PI3K is Vav-independent in murine B cells
    Elena Vigorito, Elizabeth Clayton, Martin Turner · 2004 · Biochemical Society Transactions
  36. Silencing of phospholipase C gamma 2 promotes proliferation of rat hepatocytes in vitro
    Xiaoguang Chen, Xuemin Zhu, Yumei Liu, Qiongxia Lv, Jun Ma · 2017 · Journal of Cellular Biochemistry
  37. Self-nonself Recognition through B-Cell Antigen Receptor
    Daisuke Kitamura · 2008 · Springer eBooks
  38. Phosphorylation at Y317 on Syk negatively regulates both ITAM- and hemITAM-mediated signaling and function in platelets
    Manal Elzoheiry, Carol Dangelmaier, Dhruv N Vajipayajula, Monica N. Wright, Alexander Y. Tsygankov, Satya P. Kunapuli · 2025 · Blood Advances
  39. Double knockout mice show BASH and PKCδ have different epistatic relationships in B cell maturation and CD40-mediated activation
    Takuya Nojima, Katsuhiko Hayashi, Ryo Goitsuka, Keiko Nakayama, Keiko Nakayama, Daisuke Kitamura · 2006 · Immunology Letters
  40. Construction of recombinant adenovirus Ad-rat PLCg2-shRNA and successful suppression of PLCg2 expression in BRL-3A cells
    Xuguang Chen, Q X Lv, Xufei Zhou · 2016 · Genetics and Molecular Research
  41. Molecular characterization and expression analysis of olive flounder ( Paralichthys olivaceus ) phospholipase C gamma 1 and gamma 2
    Soo Ji Woo, Hyae In Jo, Hyung Ho Lee, Joon Ki Chung · 2016 · Fish & Shellfish Immunology
  42. Structure and Signalling Function of the B-Cell Antigen Receptor and Its Coreceptors
    Michael G. Reth, Kathrin Kläsener, Lars Nitschke, Michael R. Gold · 2024 · Elsevier eBooks
  43. Structure and Function of B Cell Antigen Receptor Complexes
    Michael G. Reth, Jürgen Wienands · 2004 · Elsevier eBooks
  44. Structure and Signaling Function of the B-Cell Antigen Receptor and Its Coreceptors
    Michael G. Reth, Lars Nitschke, Masaki Hikida, Tomohiro Kurosaki · 2014 · Elsevier eBooks
  45. Diagnóstico molecular de enfermedades de base genética que afectan al sistema inmune
    Mónica Martínez‐Gallo · 2007 · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
  46. Kidins220 regulates the development of B cells bearing the λ light chain
    Anna-Maria Schaffer, Gina J. Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Marie Babrak, Laurenz A. Herr, Mari Carmen Romero-Mulero, Nina Cabezas‐Wallscheid, Marta Rizzi, Enkelejda Miho et al. · 2023 · eLife
  47. PLCγ2 deficiency compromises systemic immune tolerance and erodes myelin homeostasis while enhancing oxidative metabolism in the mouse brain
    Gutierrez-Kuri, Eduardo, Marie Garcia-Rogers, Juliet Lynn, Perez, Jaid, Smith, Sabrina, Kenwood, Matthew R., Archuleta, Kahealani S., Xiao, Yangming, Campos, Gabriela, Barannikov, Savannah, Wang, Hu et al. · 2026
  48. Regulation of phospolipase C-γ2 and phosphoinositide 3-kinase by adaptor proteins in B cells
    Tomohiro Kurosaki · 2001 · Springer eBooks
  49. Expression and function of the αVβ5 integrin during human B lymphopoiesis
    Mridu Acharya · 2008 · Enlighten: Theses (The University of Glasgow)
  50. Cellular and Physiological Functions of Phosphoinositide-Metabolizing Enzymes
    Makoto Fujii, Satomi Kita, Ichiro Horie, Yusuke Gotoh, Takahiro Iwamoto · 2012 · Institutional Repositories DataBase (IRDB)
  51. PROKARYOTIC EXPRESSION AND PURIFICATION OF PLC-γ2
    Rodica Aura Badea, Stefan Eugen Szedlacsek · 2011
  52. Regulation of B Cell Gene Expression and Function by Ikaros, Helios and Bcl6
    Jukka Alinikula · 2010 · UTUPub (University of Turku)
  53. B cell development in fetal liver and adult bone marrow
    Sandra Düber · 2004 · Digitale Bibliothek Braunschweig (Verbundzentrale Göttingen (VZG))
  54. Activation of B1 Cells
    Diego Catalán, Carolina Hager Ribeiro · 2025 · Elsevier eBooks
  55. Elucidating the Vulnerability of Glioblastoma Stem-like Cells to Lysosomal Dysfunctions
    Clément Maghe · 2023 · theses.fr (ABES)
  56. Diacylglycerol Kinases Balance DAG Signaling to Control B Cell Maturation, Germinal Center Homeostasis, and Humoral Immunity
    Jinhai Xie, Shimeng Zhang, Wendy Lee, Huishan Tao, Yun Pan, Xunrong Luo, Xiao‐Ping Zhong · 2026 · bioRxiv (Cold Spring Harbor Laboratory)