Cutting Edge: Essential Role of Phospholipase C-γ2 in B Cell Development and Function
Hashimoto, Ari, Takeda, Kiyoshi, Inaba, Muneo, Sekimata, Masayuki, Kaisho, Tsuneyasu, Ikehara, Susumu, Homma, Yoshimi, Akira, Shizuo, Kurosaki, Tomohiro·2000·The Journal of Immunology
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Items 101–156 of 156
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- PLCγ2: where bone and immune cells find their common groundRoberta Faccio, Viviana Cremasco · 2010 · Annals of the New York Academy of Sciences
- Btk and phospholipase Cγ2 can function independently during B cell developmentKristina E. Halcomb, Cristina M. Contreras, Rochelle M. Hinman, Terry G. Coursey, Heather L. Wright, Anne B. Satterthwaite · 2007 · European Journal of Immunology
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- Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN- productionShinya Hidano, H. Sasanuma, K. Ohshima, Ken‐ichiro Seino, Lalit Kumar, Katsuhiko Hayashi, Minami Hikida, Tomohiro Kurosaki, Masaru Taniguchi, Raif S. Geha et al. · 2008 · International Immunology
- BCR signal through α4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutationInui, Seiji, Maeda, Kazuhiko, Hua, Ding Rong, Yamashita, Takeshi, Yamamoto, Hideyuki, Miyamoto, Eishichi, Aizawa, Shinichi, Sakaguchi, Nobuo · 2002 · International Immunology
- Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase CγAdrienne Halupa, Manprit Chohan, Natalie H. Stickle, Bryan K. Beattie, Barbara A. Miller, Dwayne L. Barber · 2005 · Experimental Cell Research
- Regulation of Phospholipase C‐γ2 Networks in B LymphocytesMasaki Hikida, Tomohiro Kurosaki · 2005 · Advances in immunology
- PLCγ2 impacts microglia-related effectors revealing variants and pathways important in Alzheimer’s diseaseLi, Ke, Ran, Beibei, Wang, Yu, Liu, Lulu, Li, Weidong · 2022 · Frontiers in Cell and Developmental Biology
- Phospholipids: “Greasing the wheels” of humoral immunityJoseph W. Brewer · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Phospholipase Cγ1 (PLCγ1) Controls Osteoclast Numbers via Colony-stimulating Factor 1 (CSF-1)-dependent Diacylglycerol/β-Catenin/CyclinD1 PathwayZhengfeng Yang, Seokho Kim, Sahil Mahajan, Ali Zamani, Roberta Faccio · 2016 · Journal of Biological Chemistry
- Identification of genes involved in immune response of Atlantic salmon (Salmo salar) to IPN virus infection, using expressed sequence tag (EST) analysisVictoria Cepeda, Catalina Cofré, Ruth González, Simon A MacKenzie, Rodrigo Vidal · 2011 · Aquaculture
- Regulation of Phospholipase C-γ2 and Phosphoinositide 3-Kinase Pathways by Adaptor Proteins In B LymphocytesTomohiro Kurosaki, Takaharu Okada · 2001 · International Reviews of Immunology
- BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP responseMasayuki P. Yamamoto · 2004 · International Immunology
- Proximal B cell receptor signaling pathwaysBrian J. Skaggs, Marcus R. Clark · 2004 · Signal Transduction
- PKCη directs induction of IRF-4 expression and Ig κ gene rearrangement in pre-BCR signaling pathwayAkihisa Oda, Tomohiro Ono, Mutsumi Yamamoto, Ryo Goitsuka, Daisuke Kitamura · 2008 · International Immunology
- Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implicationsTina Nguyen, Elissa K. Deenick, Stuart G. Tangye · 2021 · Expert Review of Clinical Immunology
- Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1Yongwei Zheng, Tamara L. Adams, Huiying Zhi, Mei Yu, Renren Wen, Peter J. Newman, Demin Wang, Debra K. Newman · 2015 · PLoS ONE
- Distinct Roles of Phosphoinositide-3 Kinase and Phospholipase Cγ2 in B-Cell Receptor-Mediated Signal TransductionDai, Xuezhi, Chen, Yuhong, Schuman, James, Hua, Zichun, Adamson, John W., Wen, Renren, Wang, Demin · 2006 · Molecular and Cellular Biology
- Phospholipases in Health and DiseaseYong Ryoul Yang, Hyun‐Jun Jang, Sung Ho Ryu, Pann‐Ghill Suh · 2014 · Springer eBooks
- Phospholipase Cγ2 Dosage Is Critical for B Cell Development in the Absence of Adaptor Protein BLNKXu, Shengli, Huo, Jianxin, Chew, Weng-Keong, Hikida, Masaki, Kurosaki, Tomohiro, Lam, Kong-Peng · 2006 · The Journal of Immunology
- A hypomorphic IgH‐chain allele affects development of B‐cell subsets and favours receptor editingSven Brenner, Diana Drewel, Thomas Steinbart, Florian J. Weisel, Eric Haertel, Sonja Pötzsch, Heike Welzel, Andreas Brandl, Philipp Yu, Geert C. Mudde et al. · 2011 · The EMBO Journal
- Phospholipase Cγ2 Is Essential for Experimental Models of Epidermolysis Bullosa AcquisitaKata P. Szilveszter, Simon Vikár, Ádám István Horváth, Zsuzsanna Helyes, Miklós Sárdy, Attila Mócsai · 2021 · Journal of Investigative Dermatology
- Neutrophil Phospholipase Cγ2 Drives Autoantibody‐Induced Arthritis Through the Generation of the Inflammatory MicroenvironmentKrisztina Futosi, Orsolya Kása, Kata P. Szilveszter, Attila Mócsai · 2021 · Arthritis & Rheumatology
- NF‐κB signaling in B‐1 cell developmentGabriel Kristian Pedersen, Mónika Ádori, Gunilla B. Karlsson Hedestam · 2015 · Annals of the New York Academy of Sciences
- Re-distribution of phospholipase C gamma 2 in macrophage precursors is mediated by the actin cytoskeleton under the control of the Src kinasesMarie-Therese Dearden-Badet, Guy Mouchiroud · 2005 · Cellular Signalling
- Phospholipase C-γ Contains Introns Shared by src Homology 2 Domains in Many Unrelated ProteinsCharlene M Manning, Wendy R Mathews, Leah P Fico, Justin R. Thackeray · 2003 · Genetics
- Activation of Phospholipase C 2 by Tyrosine PhosphorylationFatih Özdener, Carol Dangelmaier, Barrie Ashby, Satya P. Kunapuli · 2002
- Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthmaMiguel A. Hernandez‐Lara, Joshua Richard, Deepak A. Deshpande · 2024 · American Journal of Physiology-Lung Cellular and Molecular Physiology
- Distinct Phospholipase C-γ-Dependent Signaling Pathways in the Drosophila Eye and Wing Are Revealed by a New small wing AlleleRishikesh Mankidy, Jeremy Hastings, Justin R. Thackeray · 2003 · Genetics
- Variations in the human phospholipase Cγ2 gene in patients with B-cell defects of unknown etiologyD. Wang, E. C. Boylin, Y. Minegishi, R. Wen, Edvard C. I. Smith, J. Ihle, M. Conley · 2001 · Immunogenetics
- Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinaseLindsey R. Whyburn · 2003 · International Immunology
- Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in MiceHirotake Ichise, Taeko Ichise, Nobuaki Yoshida · 2016 · PLoS ONE
- BCR activation of PI3K is Vav-independent in murine B cellsElena Vigorito, Elizabeth Clayton, Martin Turner · 2004 · Biochemical Society Transactions
- Silencing of phospholipase C gamma 2 promotes proliferation of rat hepatocytes in vitroXiaoguang Chen, Xuemin Zhu, Yumei Liu, Qiongxia Lv, Jun Ma · 2017 · Journal of Cellular Biochemistry
- Self-nonself Recognition through B-Cell Antigen ReceptorDaisuke Kitamura · 2008 · Springer eBooks
- Phosphorylation at Y317 on Syk negatively regulates both ITAM- and hemITAM-mediated signaling and function in plateletsManal Elzoheiry, Carol Dangelmaier, Dhruv N Vajipayajula, Monica N. Wright, Alexander Y. Tsygankov, Satya P. Kunapuli · 2025 · Blood Advances
- Double knockout mice show BASH and PKCδ have different epistatic relationships in B cell maturation and CD40-mediated activationTakuya Nojima, Katsuhiko Hayashi, Ryo Goitsuka, Keiko Nakayama, Keiko Nakayama, Daisuke Kitamura · 2006 · Immunology Letters
- Construction of recombinant adenovirus Ad-rat PLCg2-shRNA and successful suppression of PLCg2 expression in BRL-3A cellsXuguang Chen, Q X Lv, Xufei Zhou · 2016 · Genetics and Molecular Research
- Molecular characterization and expression analysis of olive flounder ( Paralichthys olivaceus ) phospholipase C gamma 1 and gamma 2Soo Ji Woo, Hyae In Jo, Hyung Ho Lee, Joon Ki Chung · 2016 · Fish & Shellfish Immunology
- Structure and Signalling Function of the B-Cell Antigen Receptor and Its CoreceptorsMichael G. Reth, Kathrin Kläsener, Lars Nitschke, Michael R. Gold · 2024 · Elsevier eBooks
- Structure and Function of B Cell Antigen Receptor ComplexesMichael G. Reth, Jürgen Wienands · 2004 · Elsevier eBooks
- Structure and Signaling Function of the B-Cell Antigen Receptor and Its CoreceptorsMichael G. Reth, Lars Nitschke, Masaki Hikida, Tomohiro Kurosaki · 2014 · Elsevier eBooks
- Diagnóstico molecular de enfermedades de base genética que afectan al sistema inmuneMónica Martínez‐Gallo · 2007 · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
- Kidins220 regulates the development of B cells bearing the λ light chainAnna-Maria Schaffer, Gina J. Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Marie Babrak, Laurenz A. Herr, Mari Carmen Romero-Mulero, Nina Cabezas‐Wallscheid, Marta Rizzi, Enkelejda Miho et al. · 2023 · eLife
- PLCγ2 deficiency compromises systemic immune tolerance and erodes myelin homeostasis while enhancing oxidative metabolism in the mouse brainGutierrez-Kuri, Eduardo, Marie Garcia-Rogers, Juliet Lynn, Perez, Jaid, Smith, Sabrina, Kenwood, Matthew R., Archuleta, Kahealani S., Xiao, Yangming, Campos, Gabriela, Barannikov, Savannah, Wang, Hu et al. · 2026
- Regulation of phospolipase C-γ2 and phosphoinositide 3-kinase by adaptor proteins in B cellsTomohiro Kurosaki · 2001 · Springer eBooks
- Expression and function of the αVβ5 integrin during human B lymphopoiesisMridu Acharya · 2008 · Enlighten: Theses (The University of Glasgow)
- Cellular and Physiological Functions of Phosphoinositide-Metabolizing EnzymesMakoto Fujii, Satomi Kita, Ichiro Horie, Yusuke Gotoh, Takahiro Iwamoto · 2012 · Institutional Repositories DataBase (IRDB)
- PROKARYOTIC EXPRESSION AND PURIFICATION OF PLC-γ2Rodica Aura Badea, Stefan Eugen Szedlacsek · 2011
- Regulation of B Cell Gene Expression and Function by Ikaros, Helios and Bcl6Jukka Alinikula · 2010 · UTUPub (University of Turku)
- B cell development in fetal liver and adult bone marrowSandra Düber · 2004 · Digitale Bibliothek Braunschweig (Verbundzentrale Göttingen (VZG))
- Activation of B1 CellsDiego Catalán, Carolina Hager Ribeiro · 2025 · Elsevier eBooks
- Elucidating the Vulnerability of Glioblastoma Stem-like Cells to Lysosomal DysfunctionsClément Maghe · 2023 · theses.fr (ABES)
- Diacylglycerol Kinases Balance DAG Signaling to Control B Cell Maturation, Germinal Center Homeostasis, and Humoral ImmunityJinhai Xie, Shimeng Zhang, Wendy Lee, Huishan Tao, Yun Pan, Xunrong Luo, Xiao‐Ping Zhong · 2026 · bioRxiv (Cold Spring Harbor Laboratory)