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Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites
Abstract
Fibrocytes are a distinct population of blood-borne cells that display a unique cell surface phenotype (collagen I+/CD11b+/CD13+/CD34+/CD45RO+/MHC class II+/CD86+) and exhibit potent immunostimulatory activities. Circulating fibrocytes rapidly enter sites of tissue injury, suggesting an important role for these cells in wound repair. However, the regulatory processes that govern the differentiation of blood-borne fibrocytes and the mechanisms that underlie the migration of these cells to wound sites are currently not known. We report herein that ex vivo cultured fibrocytes can differentiate from a CD14+-enriched mononuclear cell population and that this process requires contact with T cells. Furthermore, we demonstrate that TGF-β1 (1–10 ng/ml), an important fibrogenic and growth-regulating cytokine involved in wound healing, increases the differentiation and functional activity of cultured fibrocytes. Because fibrocytes home to sites of tissue injury, we examined the role of chemokine/chemokine receptor interactions in fibrocyte trafficking. We show that secondary lymphoid chemokine, a ligand of the CCR7 chemokine receptor, acts as a potent stimulus for fibrocyte chemotaxis in vitro and for the homing of injected fibrocytes to sites of cutaneous tissue injury in vivo. Finally, we demonstrate that differentiated, cultured fibrocytes express α smooth muscle actin and contract collagen gels in vitro, two characteristic features of wound-healing myofibroblasts. These data provide important insight into the control of fibrocyte differentiation and trafficking during tissue repair and significantly expand their potential role during wound healing.
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“Their migration to wounds is guided by damage associated molecular patterns (DAMPs) and chemokines such as Chemokine (C-C motif) ligand 21 (CCL21) (86), and after arrival, these cells start differentiating into a myofibroblast-like phenotype under the influence of factors such as TGFβ (86).”
From Unraveling SSc Pathophysiology; The Myofibroblast (2018) · cites this paper as [86]
In the citing paper
“Their migration to wounds is guided by damage associated molecular patterns (DAMPs) and chemokines such as Chemokine (C-C motif) ligand 21 (CCL21) (86), and after arrival, these cells start differentiating into a myofibroblast-like phenotype under the influence of factors such as TGFβ (86).”
From Unraveling SSc Pathophysiology; The Myofibroblast (2018) · cites this paper as [86]
Citations
Cites
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
Bleul, C. C., Fuhlbrigge, R. C., Casasnovas, J. M., Aiuti, A., & Springer, T. A. (1996) · The Journal of experimental medicine · doi:10.1084/jem.184.3.1101 · Cited by 1,482
Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair
Bucala, R., Spiegel, L. A., Chesney, J. A., Hogan, M. M., & Cerami, A. (1994) · Molecular Medicine · doi:10.1007/bf03403533 · Cited by 1,307
Self-citationCD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.
Zhou, L., & Tedder, T. F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.6.2588 · Cited by 1,090
Sime, P. J., Xing, Z., Graham, F. L., Csaky, K. G., & Gauldie, J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119590 · Cited by 1,050
Gunn, M. D., Kyuwa, S., Tam‐Amersdorfer, C., Kakiuchi, T., Matsuzawa, A., Williams, L. T., & Nakano, H. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.3.451 · Cited by 1,019
Myofibroblasts. I. Paracrine cells important in health and disease
Powell, D. W., Mifflin, R. C., Valentich, J. D., Crowe, S. E., Saada, J. I., & West, A. B. (1999) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1999.277.1.c1 · Cited by 974
Saeki, H., Moore, A. M., Brown, M. J., & Hwang, S. T. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.5.2472 · Cited by 623
Mechanisms of Myofibroblast Activity and Phenotypic Modulation
Serini, G., & Gabbiani, G. (1999) · Experimental Cell Research · doi:10.1006/excr.1999.4543 · Cited by 592
Branton, M., & Kopp, J. (1999) · Microbes and Infection · doi:10.1016/s1286-4579(99)00250-6 · Cited by 574
Arora, P. D., Narani, N., & McCulloch, C. A. (1999) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65334-5 · Cited by 474
Flagged first, then by citations
Research works printed but not linked: 42
- 1963, N. Engl. J. Med., 1367
- 1994, Mol. Med., 71
- 1997, Proc. Natl. Acad. Sci. USA, 6307
- 1999, Mol. Med., 46
- 1998, J. Immunol., 419
- 1999, Am. J. Pathol., 2087
- 1999, Am. J. Pathol., 871
- 1998, J. Exp. Med., 297
- 1996, J. Exp. Med., 1101
- 1998, Life Sci., 1779
- 1999, J. Clin. Invest., 1097
- 1998, J. Clin. Invest., 1933
- 1998, FEBS Lett., 188
- 1999, J. Immunol., 2472
- 1999, J. Immunol., 3985
- 1997, J. Biol. Chem., 30911
- 2000, Exp. Cell Res., 180
- 1999, Exp. Cell Res., 273
- 1999, Am. J. Physiol, C1
- 1998, J. Immunol., 419
- 1997, Biochem. Soc. Trans., 520
- 1995, Adv. Exp. Med. Biol., 75
- 1996, J. Immunol., 3850
- 1996, Proc. Natl. Acad. Sci. USA, 2588
- 1997, Eur. J. Immunol., 431
- 1999, Immunity, 625
- 1999, J. Immunol., 3231
- 1999, Microbes. Infect., 1349
- 1999, J. Am. Coll. Surg., 271
- 1999, Am. J. Respir. Cell Mol. Biol., 658
- 1999, J. Surg. Res., 194
- 1987, J. Surg. Res., 622
- 1996, J. Clin. Invest., 2894
- 1999, Springer Semin. Immunopathol., 385
- 1999, J. Immunol., 5693
- 1997, J. Clin. Invest., 768
- 1999, Curr. Top. Pathol., 35
- 1999, J. Immunol., 2472
- 2000, Am. J. Pathol., 1133
- 1999, J. Exp. Med., 451
- 1998, Blood, 2886
- 1997, Eur. J. Immunol., 215
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Items 501–600 of 965
Fibrocytes in Asthma and Chronic Obstructive Pulmonary Disease: Variations on the Same Theme
Dupin, I., Contin‐Bordes, C., & Berger, P. (2017) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2017-0301ps · Cited by 32
Biomarkers for PVR in rhegmatogenous retinal detachment
Zandi, S., Pfister, I. B., Traine, P. G., Tappeiner, C., Despont, A., Rieben, R., Skowronska, M., & Garweg, J. G. (2019) · PLoS ONE · doi:10.1371/journal.pone.0214674 · Cited by 34
Ishii, G., Ito, T. K., Aoyagi, K., Fujimoto, H., Chiba, H., Hasebe, T., Fujii, S., Nagai, K., Sasaki, H., & Ochiai, A. (2007) · Stem Cells · doi:10.1634/stemcells.2006-0449 · Cited by 34
The role of CD200–CD200R in tumor immune evasion
Liao, K., Bai, X., & Friedman, A. (2013) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2013.03.017 · Cited by 34
Blocki, A. M., Wang, Y., Koch, M. K., Goralczyk, A. G., Beyer, S., Agarwal, N., Lee, M. H., Moonshi, S. S., Dewavrin, J., Peh, P., et al. (2014) · Molecular Therapy · doi:10.1038/mt.2014.232 · Cited by 34
Sato, M., Hirayama, S., Lara-Guerra, H., Anraku, M., Waddell, T. K., Liu, M., & Keshajee, S. (2009) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2009.02605.x · Cited by 34
Inhibitory effects of trehalose on fibroblast proliferation and implications for ocular surgery
Takeuchi, K., Nakazawa, M., Ebina, Y., Sato, K., Metoki, T., Miyagawa, Y., & Ito, T. (2010) · Experimental Eye Research · doi:10.1016/j.exer.2010.07.002 · Cited by 34
Stem cell plasticity and tumour formation
Alison, M. R., Lovell, M. J., Direkze, N. C., Wright, N. A., & Poulsom, R. (2006) · European Journal of Cancer · doi:10.1016/j.ejca.2006.01.034 · Cited by 34
Inhibitors of CXC chemokine receptor type 4
Hummel, S., Aken, H. V., & Zarbock, A. (2013) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000002 · Cited by 33
Kakudo, N., Kushida, S., Suzuki, K., Ogura, T., Notodihardjo, P. V., Hara, T., & Kusumoto, K. (2012) · Human Cell · doi:10.1007/s13577-012-0049-0 · Cited by 34
Stamm, I., Mohr, M., Bridger, P. S., Schröpfer, E., König, M., Stoffregen, W. C., Dean-Nystrom, E. A., Baljer, G., & Menge, C. (2008) · Infection and Immunity · doi:10.1128/iai.00553-08 · Cited by 33
The roles of chemokines in leukocyte recruitment and fibrosis in systemic sclerosis
Hasegawa, M. (2008) · Frontiers in bioscience · doi:10.2741/2955 · Cited by 32
MCP1 Directs Trafficking of Hematopoietic Stem Cell-Derived Fibroblast Precursors in Solid Tumor
Abangan, R. S., WILLIAMS, C. R., Mehrotra, M., Duncan, J. D., & LaRue, A. C. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.080839 · Cited by 33
NADPH Oxidase Inhibition in Fibrotic Pathologies
Bernard, K. F., & Thannickal, V. J. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8032 · Cited by 34
Abnormal wound healing responses in pulmonary fibrosis: focus on coagulation signalling
Chambers, R. C. (2008) · European Respiratory Review · doi:10.1183/09059180.00010905 · Cited by 33
Sung, J. J., Chen, T. S., Gilliam, A. C., McCalmont, T. H., & Gilliam, A. E. (2011) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2010.02.065 · Cited by 33
α Smooth muscle actin positive stromal cells in gastric carcinoma
Nakayama, H., Enzan, H., Miyazaki, E., & Toi, M. (2002) · Journal of Clinical Pathology · doi:10.1136/jcp.55.10.741 · Cited by 33
A Novel Population of Repair Cells Identified in the Stroma of the Human Cornea
Thill, M., Schlagner, K., Altenähr, S., Ergün, S., Faragher, R., Kilic, N., Bednarz, J., Vohwinkel, G., Rogiers, X., HOSSFELD, D. K., et al. (2007) · Stem Cells and Development · doi:10.1089/scd.2006.0084 · Cited by 33
Maguen, E. I., Zorapapel, N. C., Zieske, J. D., Ninomiya, Y., Sado, Y., Kenney, M. C., & Ljubimov, A. V. (2002) · Cornea · doi:10.1097/00003226-200201000-00020 · Cited by 33
Nephrogenic Fibrosing Dermopathy
Scheinfeld, N. S. (2006) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200607040-00005 · Cited by 33
Monument, M. J., Hart, D. A., SALO, P. T., Befus, A. D., & Hildebrand, K. A. (2014) · Advances in Wound Care · doi:10.1089/wound.2013.0509 · Cited by 32
Holt, B. M., Betz, D. H., Ford, T. A., Beck, J. P., Bloebaum, R. D., & Jeyapalina, S. (2013) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-013-4975-5 · Cited by 32
Mayes, M. D. (2008) · Springer eBooks · doi:10.1007/978-0-387-68566-3_17 · Cited by 32
Fibroblasts and Osteoblasts in Inflammation and Bone Damage
Turner, J. D., Naylor, A. J., Buckley, C. D., Filer, A. D., & Tak, P. P. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-78127-3_3 · Cited by 32
Prognostic impact of CD34 and SMA in cancer‐associated fibroblasts in stage I–III NSCLC
Schulze, A. B., Schmidt, L. H., Heitkötter, B., Huss, S., Möhr, M., Marra, A., Hillejan, L., Görlich, D., Barth, P. J., Rehkämper, J., et al. (2019) · Thoracic Cancer · doi:10.1111/1759-7714.13248 · Cited by 32
Mäurer, M., Müller, M., Kobsar, I., Reif-Leonhard, C., Martini, R., & Kiefer, R. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00055-1 · Cited by 32
Suess, P. M., Chinea, L. E., Pilling, D., & Gomer, R. H. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1801559 · Cited by 28
Walsh, S. M., Worrell, J. C., Fabre, A., Hinz, B., Kane, R., & Keane, M. P. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00543.2017 · Cited by 32
Meephansan, J., Ungpraphakorn, N., Ponnikorn, S., Suchonwanit, P., & Poovorawan, Y. (2018) · Dermatologic Surgery · doi:10.1097/dss.0000000000001619 · Cited by 31
Nikam, V. S., Wecker, G., SCHERMULY, R. T., Rapp, U. R., Szelepusa, K., Seeger, W., & Voswinckel, R. (2011) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2010-0240oc · Cited by 31
Borena, B. M., Pawde, A. M., Amarpal, Aithal, H. P., Kinjavdekar, P., Singh, R. P., & Kumar, D. (2010) · International Wound Journal · doi:10.1111/j.1742-481x.2010.00683.x · Cited by 31
Hong, R., Zhou, Y., Tian, X., Wang, L., & Wu, X. (2017) · International Immunopharmacology · doi:10.1016/j.intimp.2017.10.008 · Cited by 31
Participation of bone marrow cells in biliary fibrosis after bile duct ligation
Asawa, S., Saito, T., Satoh, A., Ohtake, K., Tsuchiya, T., Okada, H., Neilson, E. G., & Gotoh, M. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04708.x · Cited by 31
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Varga, J., & Denton, C. P. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-3285-4.10077-4 · Cited by 28
Maekawa, T., Osawa, Y., Izumi, T., Nagao, S., Takano, K., Okada, Y., Tachi, N., Teramoto, M., Kawamura, T., Horiuchi, T., et al. (2017) · Leukemia · doi:10.1038/leu.2017.112 · Cited by 30
Lü, Y., Atkins, S. J., Fernando, R., Trierweiler, A., Mester, T., Grisolia, A. B. D., Mou, P., Novaes, P., & Smith, T. J. (2018) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.18-23951 · Cited by 30
Differentiated fibrocytes assume a functional mesenchymal phenotype with regenerative potential
Ling, C., Nishimoto, K., Rolfs, Z., Smith, L. M., Frey, B. L., & Welham, N. V. (2019) · Science Advances · doi:10.1126/sciadv.aav7384 · Cited by 30
Meloni, F., Solari, N., Miserere, S., Morosini, M., Cascina, A., Klersy, C., Arbustini, E., Pellegrini, C., Viganò, M., & Fietta, A. M. (2007) · Transplant Immunology · doi:10.1016/j.trim.2007.08.004 · Cited by 30
Transdifferentiation of Peripheral Blood Mononuclear Cells into Epithelial-Like Cells
Medina, A., Kilani, R. T., Carr, N. J., Brown, E. E., & Ghahary, A. (2007) · American Journal Of Pathology · doi:10.2353/ajpath.2007.070051 · Cited by 30
Catteau, X., Simon, P., Vanhaeverbeek, M., & Noël, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057773 · Cited by 30
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Uehara, H., Nakagawa, T., Katsuno, T., Satô, T., Isono, A., Noguchi, Y., & Saitō, Y. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-0730-7 · Cited by 30
Adult stem cells and repair through granulation tissue
Díaz‐Flores, L. (2009) · Frontiers in bioscience · doi:10.2741/3317 · Cited by 30
Kokubo, S., Sakai, N., Furuichi, K., Toyama, T., Kitajima, S., Okumura, T., Matsushima, K., Kaneko, S., & Wada, T. (2011) · Peritoneal Dialysis International · doi:10.3747/pdi.2010.00200 · Cited by 29
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Curran, T., & Ghahary, A. (2012) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e318254d1f9 · Cited by 29
Peritoneal cell culture: fibroblasts.
Witowski, J., & Jörres, A. (2006) · PubMed · Cited by 29
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Al‐Hattab, D. S., & Czubryt, M. P. (2017) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2016-0687 · Cited by 29
Lee, J.-H., Lee, D., Lawler, S. E., & Kim, Y. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1008257 · Cited by 31
Heger, M., van Golen, R. F., Broekgaarden, M., van den Bos, R. R., Neumann, H. A. M., van Gulik, T. M., & van Gemert, M. J. C. (2013) · Lasers in Medical Science · doi:10.1007/s10103-013-1490-3 · Cited by 31
XU, Z., Wang, S., Wu, M.-L., ZENG, W., Wang, X., & Dong, Z. (2013) · Oncology Letters · doi:10.3892/ol.2013.1409 · Cited by 29
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Barone, F., Nayar, S., & Buckley, C. D. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00416 · Cited by 29
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Gomer, R. H., & Lupher, M. (2010) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2010.484018 · Cited by 30
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De Biasi, S., Cerri, S., Bianchini, E., Gibellini, L., Persiani, E., Montanari, G., Luppi, F., Carbonelli, C. M., Zucchi, L., Bocchino, M., et al. (2015) · BMC Medicine · doi:10.1186/s12916-015-0515-0 · Cited by 28
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Scheja, A., Larsen, K. S., Todorova, L., Tufvesson, E., Wildt, M., Åkesson, A., Hansson, L. J., Ellis, S., & Westergren‐Thorsson, G. (2006) · European Respiratory Journal · doi:10.1183/09031936.00135205 · Cited by 28
Yamazaki, K. (2007) · Ultrastructural Pathology · doi:10.1080/01913120701350365 · Cited by 28
Brountzos, Ε., Pavčnik, D., Timmermans, H. A., Corless, C. L., Uchida, B. T., Nihsen, E. S., Nakata, M., Schoder, M., Kaufman, J. A., Keller, F. S., et al. (2003) · Journal of Vascular and Interventional Radiology · doi:10.1097/01.rvi.0000058410.01661.62 · Cited by 28
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Routray, S., Sunkavalli, A., & Bari, K. (2013) · Oral Diseases · doi:10.1111/odi.12107 · Cited by 27
Liu, L., Chen, Q., Ruan, C., Chen, X., Zhang, Y., He, X., Zhang, Y., Lü, Y., Guo, Q., Sun, T., et al. (2018) · Theranostics · doi:10.7150/thno.24110 · Cited by 27
Chan, Q. E., Harvey, J. G., Graf, N. S., Godfrey, C., & Holland, A. J. A. (2011) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e31823356ce · Cited by 27
Catteau, X., Simon, P., & Noël, J. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-499 · Cited by 27
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Fu, X., Zhang, D., Li, Y.-D., Zhao, P.-W., Tang, Y., Niu, J., & Li, Y. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000369714 · Cited by 26
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Gilpin, S. E., Lung, K. C., Sato, M., Singer, L. G., Keshavjee, S. H., & Waddell, T. K. (2012) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2011.11.012 · Cited by 26
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Metadata
- Authors
- Abe, R., Donnelly, S. C., Peng, T., Bucala, R., & Metz, C. N.
- Affiliations
- Laboratory of Vascular Biology, The Picower Institute for Medical Research , Manhasset, NY 11030
- Laboratory of Medical Biochemistry, The Picower Institute for Medical Research , Manhasset, NY 11030
- Corresponding author
- Abe, Riichiro
- Peng, Tina
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-06
- Volume
- 166
- Issue
- 12
- Pages
- 7556-7562
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W4248565951
- Cited by
- 967
- References
- 40
- Citations by year
- 2026: 13 · 2025: 15 · 2024: 22 · 2023: 25 · 2022: 28 · 2021: 23 · 2020: 37 · 2019: 30 · 2018: 34 · 2017: 31 · 2016: 43 · 2015: 47 · 2014: 58 · 2013: 59 · 2012: 68
- FWCI
- 27.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Immunology and Microbiology › Immunology › Macrophage Migration Inhibitory Factor
- Keywords
- fibrocytes, fibrocyte differentiation, wound healing, TGF-β1, CCR7, tissue damage, myofibroblasts, alpha-smooth muscle actin, collagen gel contraction
- MeSH terms
- Animals, Blood Cells, Cell Differentiation, Cell Movement, Cells, Cultured, Collagen, Female, Fibroblasts, Fibrosis, Gels, Humans, Injections, Intravenous, Mice, Inbred BALB C, Stem Cells, Wound Healing, Transforming Growth Factor beta, Lipopolysaccharide Receptors, Receptors, Chemokine, Stem Cell Transplantation, Mice, Transforming Growth Factor beta1
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