The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Lymphoid Past of Mouse Plasmacytoid Cells and Thymic Dendritic Cells
Abstract
There has been controversy over the possible lymphoid origin of certain dendritic cell (DC) subtypes. To resolve this issue, DC and plasmacytoid pre-DC isolated from normal mouse tissues were analyzed for transient (mRNA) and permanent (DNA rearrangement) markers of early stages of lymphoid development. About 27% of the DNA of CD8+ DC from thymus, and 22–35% of the DNA of plasmacytoid pre-DC from spleen and thymus, was found to contain IgH gene D-J rearrangements, compared with 40% for T cells. However, the DC DNA did not contain IgH gene V-D-J rearrangements nor T cell Ag receptor β gene D-J rearrangements. The same DC lineage populations containing IgH D-J rearrangements expressed mRNA for CD3 chains, and for pre-Tα. In contrast, little of the DNA of the conventional DC derived from spleen, lymph nodes, or skin, whether CD8+ or CD8−, contained IgH D-J rearrangements and splenic conventional DC expressed very little CD3ε or pre-Tα mRNA. Therefore, many plasmacytoid pre-DC and thymic CD8+ DC have shared early steps of development with the lymphoid lineages, and differ in origin from conventional peripheral DC.
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Cites
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
Kondo, M., Weissman, I. L., & Akashi, K. (1997) · Cell · doi:10.1016/s0092-8674(00)80453-5 · Cited by 2,253
Cited by
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Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science · doi:10.1126/science.1178331 · Cited by 3,049
Merad, M., Sathe, P., Helft, J., Miller, J., & Mortha, A. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-074950 · Cited by 2,309
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Collin, M., & Bigley, V. (2018) · Immunology · doi:10.1111/imm.12888 · Cited by 1,301
Munn, D. H., Sharma, M. D., Hou, D., Baban, B., Lee, J. R., Antonia, S. J., Messina, J. L., Chandler, P., Koni, P. A., & Mellor, A. L. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21583 · Cited by 852
Pax5 induces V -to- DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
Fuxa, M., Skok, J., Souabni, A., Salvagiotto, G., Roldan, E., & Busslinger, M. (2004) · Genes & Development · doi:10.1101/gad.291504 · Cited by 414
Metadata
- Authors
- Corcoran, L., Ferrero, I., Vremec, D., Lucas, K., Waithman, J., O’Keeffe, M., Wu, L., Wilson, A., & Shortman, K.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-05
- Volume
- 170
- Issue
- 10
- Pages
- 4926-4932
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1595037199
- Cited by
- 206
- References
- 2
- FWCI
- 5.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Corcoran, L., Ferrero, I., Vremec, D., Lucas, K., Waithman, J., O’Keeffe, M., Wu, L., Wilson, A., & Shortman, K. (2003). The Lymphoid Past of Mouse Plasmacytoid Cells and Thymic Dendritic Cells. The Journal of Immunology. https://doi.org/10.4049/jimmunol.170.10.4926
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