The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
T Follicular Helper Cells Express a Distinctive Transcriptional Profile, Reflecting Their Role as Non-Th1/Th2 Effector Cells That Provide Help for B Cells
Open accessAbstract
Effector T cell responses have long been viewed in the context of the Th1/Th2 paradigm. Recently, a third major subset of nonpolarized effector T cells that provides help to B cells has been identified. These T cells, termed T follicular helper (TFH) cells, home to the B cell areas of secondary lymphoid tissue, through interactions mediated via the chemokine receptor CXCR5 and its ligand CXCL13. Affymetrix microarrays were used to identify transcription factors, cytokines, and cell surface molecules that underlie the differentiation pathways and functional properties of the TFH subset. The transcriptional profile of human CXCR5+ TFH cells was compared with that of Th1 and Th2 cells, which enabled the identification of numerous genes expressed preferentially by TFH cells, over the other effector subsets. Certain TFH genes were also expressed by B cells and thus appear to be particularly relevant for humoral immunity. Abs were used to confirm the expression of several factors. In particular, CD84 and CD200, the cytokine IL-21, and the transcription factor BCL6 were all strongly associated with TFH cells. Gene microarrays reveal a highly distinctive transcriptional profile for a third subset of effector T cells that differs markedly from Th1 and Th2 cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Tfh cells are controlled by the transcription factor Bcl6 [197]”
From Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition) (2021) · cites this paper as [197]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Functional diversity of helper T lymphocytes
Abbas, A. K., MURPHY, K. M. M., & Sher, A. (1996) · Nature · doi:10.1038/383787a0 · Cited by 4,432
MacLennan, I. C. M. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001001 · Cited by 1,795
The lineage decisions of helper T cells
MURPHY, K. M. M., & Reiner, S. L. (2002) · Nature reviews. Immunology · doi:10.1038/nri954 · Cited by 1,690
Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets
O’Garra, A. (1998) · Immunity · doi:10.1016/s1074-7613(00)80533-6 · Cited by 1,527
Breitfeld, D., Ohl, L., Kremmer, E., Ellwart, J., Sallusto, F., Lipp, M., & Förster, R. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.11.1545 · Cited by 1,464
Noguchi, M. (1993) · Cell · doi:10.1016/0092-8674(93)90167-o · Cited by 1,338
A chemokine-driven positive feedback loop organizes lymphoid follicles
Ansel, K. M., Ngo, V. N., Hyman, P. L., Luther, S. A., Förster, R., Sedgwick, J. D., Browning, J. L., Lipp, M., & Cyster, J. G. (2000) · Nature · doi:10.1038/35018581 · Cited by 1,282
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
Shimoda, K., van Deursent, J., Sangster, M. Y., Sarawar, S. R., Carson, R. T., Tripp, R. A., Chu, C., Quelle, F. W., Nosaka, T., Vignali, D. A. A., et al. (1996) · Nature · doi:10.1038/380630a0 · Cited by 1,278
Cxc Chemokine Receptor 5 Expression Defines Follicular Homing T Cells with B Cell Helper Function
Schaerli, P., Willimann, K., Lang, A. B., Lipp, M., Loetscher, P., & Moser, B. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.11.1553 · Cited by 1,263
Parrish-Novak, J. E., Dillon, S. R., Nelson, A., Hammond, A., Sprecher, C. A., Gross, J. A., Johnston, J. V., Madden, K., Xu, W., West, J., et al. (2000) · Nature · doi:10.1038/35040504 · Cited by 1,222
Flagged first, then by citations
Research works printed but not linked: 64
- 1994, Annu. Rev. Immunol., 117
- 1999, Science, 2098
- 1996, Nature, 787
- 1988, Immunol. Rev., 5
- 1998, Immunity, 275
- 1995, Immunol. Rev., 45
- 1996, Nature, 630
- 2000, J. Exp. Med., 1545
- 2000, J. Exp. Med., 1553
- 2001, J. Exp. Med., 1373
- 1996, Cell, 1037
- 2000, Nature, 309
- 2003, Immunol. Lett., 105
- 2002, Nat. Rev. Immunol., 933
- 2003, J. Immunol., 1657
- 1996, J. Exp. Med., 2437
- 1996, J. Exp. Med., 473
- 2001, Nucleic Acids Res., E29
- 2000, Nat. Genet., 96
- 2001, J. Immunol., 3057
- 2001, Adv. Immunol., 233
- 1995, J. Immunol., 2533
- 1997, Nat. Genet., 161
- 2000, Immunity, 199
- 2000, J. Immunol., 786
- 1995, Eur. J. Immunol., 2825
- 1995, Proc. Natl. Acad. Sci. USA, 11249
- 1997, Blood, 2398
- 2001, Blood, 3513
- 2002, Eur. J. Immunol., 1640
- 2001, Blood, 3867
- 2001, Clin. Immunol., 15
- 2003, J. Immunol., 2485
- 2003, Nature, 282
- 1998, Nature, 462
- 1999, J. Immunol., 6981
- 2001, J. Exp. Med., 235
- 2002, Immunogenetics, 394
- 1999, J. Immunol., 5860
- 2001, J. Immunol., 5517
- 1997, J. Exp. Med., 993
- 1995, Nature, 260
- 2000, J. Immunol., 2932
- 2000, Immunity, 233
- 2000, Science, 1768
- 1996, Proc. Natl. Acad. Sci. USA, 6947
- 1995, Blood, 45
- 2000, Semin. Immunol., 149
- 2003, Nat. Immunol., 19
- 2001, J. Immunol., 3668
- 2000, Nature, 57
- 2001, J. Immunol., 1
- 1993, Cell, 147
- 2001, Nat. Rev. Immunol., 200
- 2002, J. Leukocyte Biol., 856
- 2003, J. Immunol., 5464
- 2002, Immunity, 559
- 2002, J. Exp. Med., 969
- Cell, 265
- 1996, Blood, 5257
- 1995, Blood, 28
- 2000, J. Exp. Med., 1841
- 2003, J. Immunol., 2435
- 2003, Eur. J. Immunol., 1105
Cited by
Sorted by citations
Items 601–700 of 720
Deenick, E. K., & Tangye, S. G. (2008) · Nature · doi:10.1038/455745a · Cited by 2
Self-citationT helper cell differentiation: IL‐21 and T helper cell differentiation: Jack of all trades?
King, C. (2008) · Immunology and Cell Biology · doi:10.1038/icb.2008.51 · Cited by 2
Complex Interplays in Immune T-Cell Differentiation and Developmental Fate Determination
Duc, H. T. (2011) · Immunotherapy · doi:10.2217/imt.11.95 · Cited by 2
T Cells and Their Subsets in Autoimmunity
Burkett, P. R., Pawlak, M., Peters, A., & Kuchroo, V. K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812102-3.00006-3 · Cited by 2
Kasahara, T. M., Monteiro, C., Hygino, J., Cafasso, M. O. S. D., Oyamada, H. A. A., de Andrade, R. M., Junior, O. D. C. F., Leite, S., Silva, V. G., Gupta, S., et al. (2019) · American Journal of Reproductive Immunology · doi:10.1111/aji.13204 · Cited by 2
Lalinde-Ruiz, N., Rodríguez, I. J., Bernal-Estévez, D. A., & Parra-López, C. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111599 · Cited by 2
Lewko, W. M., & Oldham, R. K. (2009) · Springer eBooks · doi:10.1007/978-90-481-2289-9_8 · Cited by 2
Wu, H., Fu, Q., Teng, Y., Mu, P., Chen, J., & Chen, X. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08827-1 · Cited by 2
Pathobiology of Peripheral T-Cell Lymphomas
de Leval, L., & Gaulard, P. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-386456-7.04111-3 · Cited by 2
Surgical treatment of the dilated aortic root in a child with Marfan's syndrome.
Modry, D. L., Limacher, J. M., & Dobell, A. R. C. (1981) · PubMed · Cited by 2
Cytokine Regulation of B Cell Activation and Differentiation
Baba, Y., Ripley, B., Kishimoto, T., & Kurosaki, T. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-374279-7.09017-2 · Cited by 2
T Follicular Helper Cells in HIV Infection
van Lunzen, J., & Lindqvist, M. (2014) · Springer eBooks · doi:10.1007/978-1-4614-9610-6_181-1 · Cited by 2
Thielen, C., & Heinen, E. (2010) · Wiley eBooks · doi:10.1002/9780470015902.a0000517.pub3 · Cited by 2
CD200 expression in CD4 + T‐cells: Diagnostic implications across T‐cell lymphomas
Chiriac, R., Donzel, M., Pourchet, V., & Baseggio, L. (2025) · Cytometry Part B Clinical Cytometry · doi:10.1002/cyto.b.22266 · Cited by 1
Gene expression profiling of peripheral T-cell lymphoma: from bench to bedside
Piccaluga, P. P., Rossi, M., Gazzola, A., Sapienza, M. R., Mannu, C., Righi, S., Agostinelli, C., Sista, M. T., & Pileri, S. A. (2009) · Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) · doi:10.4081/hmr.v3i1.528 · Cited by 1
Particulate-Driven Type-2 Immunity and Allergic Responses
Kuroda, E., Temizoz, B., Coban, C., Ozasa, K., & Ishii, K. J. (2016) · Current topics in environmental health and preventive medicine · doi:10.1007/978-981-10-0351-6_5 · Cited by 1
Herek, T. A., & Cutucache, C. E. (2017) · Frontiers in Oncology · doi:10.3389/fonc.2017.00086 · Cited by 1
de Mestral, S. G., Dubois, R., Gibier, J., Humez, S., Lefèvre, G., Morschhauser, F., & Copin, M. (2020) · Pathology - Research and Practice · doi:10.1016/j.prp.2020.153004 · Cited by 1
The frequency of Tim-3 on circulating Tfh cells was increased in type 2 diabetes mellitus patients
Guo, S., Yu, X., Wang, L., Jing, J., Sun, Y., Li, N., Kuang, J., Zhao, D., Yu, X., Yang, J., et al. (2020) · European Journal of Inflammation · doi:10.1177/2058739220982803 · Cited by 1
The Biology of IgE: The Generation of High-Affinity IgE Antibodies
de Lafaille, M. A. C., & Lafaille, J. J. (2009) · Humana Press eBooks · doi:10.1007/978-1-60761-451-7_3 · Cited by 1
Mosmann, T. R., Rebhahn, J. A., Rosa, S. C. D., Keefer, M. C., McElrath, M. J., Rouphael, N., Pantaleo, G., Gilbert, P. B., Corey, L., Kobie, J. J., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1347926 · Cited by 1
Molecular Profiling of Peripheral T-Cell Lymphomas
Piccaluga, P. P., & Pileri, S. A. (2013) · Humana Press eBooks · doi:10.1007/978-1-62703-408-1_3 · Cited by 1
Interleukin-21 and Cancer Therapy
Davis, I. D., Skak, K., Hunder, N. N. H., Smyth, M. J., & Sivakumar, P. V. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0170-5_3 · Cited by 1
Park, H.-J., Kim, D.-H., & Choi, J. (2013) · Hanyang Medical Reviews · doi:10.7599/hmr.2013.33.1.10 · Cited by 1
GALT CD4+PD-1hi T follicular helper (Tfh) cells repopulate after anti-retroviral therapy
Onabajo, O. O., Lewis, M. G., & Mattapallil, J. J. (2021) · Cellular Immunology · doi:10.1016/j.cellimm.2021.104396 · Cited by 1
Identification of Antigen Presenting Cell Subsets Supporting Human Tfh Differentiation
Alaoui, L., Durand, M., & Segura, É. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1736-6_11 · Cited by 1
The role of TH17 cells in a model of rheumatoid arthritis
Patakas, A. (2011) · Enlighten: Theses (The University of Glasgow) · Cited by 1
Immune monitoring in humans after manipulation by B cell depletion and immunization
Vallerskog, T. (2007) · Figshare · Cited by 1
Induction of high Bcl6 expression and its roles in germinal center B cells
Arguni, E., Tsuruoka, N., Arima, M., Sakamoto, A., Hatano, M., & Tokuhisa, T. (2005) · International Congress Series · doi:10.1016/j.ics.2005.07.026 · Cited by 1
Correction: Cytokines in the Germinal Center Niche Antibodies 2016, 5(1), 5
Jandl, C., & King, C. (2016) · Antibodies · doi:10.3390/antib5020010 · Cited by 2
BAFF Regulates T Follicular Helper Cells in Autoimmunity
Coquery, C. M. (2014) · doi:10.18130/v3bz6b · Cited by 1
Wu, V. H., Nordin, J. M. L., Pampena, M. B., Rachimi, S., Burgess, W. L., Clark, M., Robinson, J. A., Estrada, P. M. D. R., Schleimann, M. H., Torres-Ruiz, F., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.11.693731 · Cited by 1
Immune Responses in Perforin Deficient Mice
Simkins, H. M. A. (2009) · Open Access Victoria University of Wellington | Te Herenga Waka (Figshare) · doi:10.26686/wgtn.16968397.v1 · Cited by 1
IL-25, another promoter of allergy
Angkasekwinai, P., & Dong, C. (2009) · Birkhäuser Basel eBooks · doi:10.1007/978-3-7643-8681-8_6
Étude comparative de la réponse des lymphocytes B humains naïfs et mémoires in vitro
Fecteau, J.-F. (2007)
B cell help provided by human γδ T cells
Bansal, R. R. (2012) · ORCA Online Research @Cardiff (Cardiff University)
Migration of Functionally Specialized T-Helper Cells: TFH Cells, Th17 Cells and FoxP3+ T Cells
Kim, C. H. (2010) · Translational research in biomedicine · doi:10.1159/000274477
Molecular Profiling and Prognosis in T-Cell Lymphomas
Piccaluga, P. P., & Pileri, S. A. (2012) · Humana Press eBooks · doi:10.1007/978-1-62703-170-7_3
CD83 as a drug target in GVHD and humoral immunity
Wong, K. Y. (2015) · The University of Queensland · doi:10.14264/uql.2015.793
Bildung, Erhaltung und Funktion von humanen regulatorischen und Gedächtnis T-Zellen
Geginat, J. A. E. (2009) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-9080
Castillo-Méndez, S. I. (2011) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2011.tde-26102011-170611
Ros, X. R. (2005) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
Tolerogenic CD4-8- Dendritic Cells and their Conversion into Immunogenic Ones via TLR9 Signaling
Zhang, X. (2008) · University Library - University of Saskatchewan (University of Saskatchewan)
Research Highlight An Expanding Job Description for Bcl6
Bi, E., & Ye, B. H. (2015)
Linterman, M. A., & Vinuesa, C. G. (2005)
Pizcueta, P. M., Kalko, P. E., Tovar, V., Zapater, N., & Calvo, M. M. P. (2013)
Identification of novel genes associated with allergen-driven T cell activation in human atopics
Bosco, A. (2007) · UWA Profiles and Research Repository (UWA)
Debuisson, D., Mari, N., Denanglaire, S., Léo, O., & Andris, F. (2014) · PLoS ONE · doi:10.1371/annotation/b0c3d5f5-5778-48af-85ed-abf1b9113a48
Regulation of the germinal center response by T follicular helper cells and type I interferons
Dahlgren, M. W. (2016) · Lund University Publications (Lund University)
immune signal in T and NK cells.
Messal, N., Mamessier, É., Celis‐Gutierrez, J., Thibult, M., Chetaille, B., Pastor, S., & Wang, Q. (2011)
Toward the stratification and personalization of common variable immunodeficiency treatment
Aryan, Z., Aghamohammadi, A., & Rezaei, N. (2016) · Expert Opinion on Orphan Drugs · doi:10.1080/21678707.2016.1205480
Bergerhoff, K. F. (2016) · UCL Discovery (University College London)
Eastaff‐Leung, N. (2009) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)
Ximenis, A. C. (2014) · TDX (Tesis Doctorals en Xarxa)
Adaptive Immunity including Organization of Lymphoid Tissues
Dustin, M. L. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-3285-4.10017-8
Advances in biological function of interleukin-21 and inflammatory bowel disease
Zhang, F., Zhang, X., Liu, D., Wang, W., & Liu, J. (2008) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v16.i19.2131
Lymphoid and non-lymphoid cell microenvironment of lymphoid follicles
Gualeni, A. V., Volpi, C. C., Carbone, A., & Gloghini, A. (2015) · doi:10.2217/fmeb2014.14.34
James, K. R. (2017) · The University of Queensland · doi:10.14264/uql.2017.339
Atypical Immune Functions of CD95/CD95L
Poissonnier, A., & Legembre, P. (2017) · Resistance to targeted anti-cancer therapeutics · doi:10.1007/978-3-319-56805-8_7
Krenács, L., Schaerli, P., Kis, G., & Bagdi, E. (2011)
Precision Medicine Approach to Improving Reconstructive Surgery Outcomes for Breast Cancer Survivors
Degen, K. E. (2018) · VTechWorks (Virginia Tech)
Chen, Y., Atnerkar, A., & Yu, D. (2016) · Wiley eBooks · doi:10.1002/9780470015902.a0024155
Tfh Lymphoma: Analysis of a RHOA Mutation & Establishment of a Pre-Clinical Model
Allchin, R. L. (2019) · Figshare
Immune mechanisms that determine the quality of antibody responses to vaccines
Lindgren, G. (2019) · Figshare
The role of mast cells, T cells and their cytokines in Allergic Conjunctivitis
Zaki, A. M. (2019) · UCL Discovery (University College London)
The role of IL-1 and MyD88 signal for protective immunity against pathogenic bacteria infection
양형준 (2013) · Seoul National University Open Repository (Seoul National University)
Haque, R., Kim, Y., Jang, H., Kim, S. Y., Lee, H., & Kim, H. J. (2020) · doi:10.22541/au.159285518.86190800
The role of PU.1 and IRF4 interaction in the biology and function of T helper 2 cells
Ahyi, A.-N. N. (2009) · IUScholarWorks (Indiana University) · doi:10.7912/c2/1686
(2021) · Wiley eBooks · doi:10.1002/9781119611288.refs
Carter, R. (2010) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.2046956.1626054
Kawachi, I., & Kondo, T. (2009) · Wiley eBooks · doi:10.1002/9780470015902.a0001224.pub2
Cormier, Y. F. (2006) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.10145.467635
Snow, E. C. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.13093957.14653169
Blazar, B. R., & Bucher, C. M. (2009) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1148074.605187
(2014) · ASM Press eBooks · doi:10.1128/9781555815653.refs
Schuitemaker, H. (2011) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.8055956.8442054
T Follicular Helper Cells in HIV Infection
van Lunzen, J., & Lindqvist, M. (2018) · Springer eBooks · doi:10.1007/978-1-4939-7101-5_181
Novel Targets and Therapies in T Cell Lymphoma
Kesavan, M., & Collins, G. P. (2018) · EMJ Oncology · doi:10.33590/emjoncol/10310205
Mary, R., Chalmin, F., Accogli, T., Bruchard, M., Hibos, C., Melin, J., Truntzer, C., Limagne, E., Dérangère, V., Thibaudin, M., et al. (2023) · doi:10.1158/2326-6066.c.6550673
T follicular helper cells in food allergy
Lu, M.-P., Lee, D., Eisenbarth, S. C., & Gowthaman, U. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-96018-2.00061-4
zhang, Z., He, J., Zhu, Y., & He, W. (2023) · Research Square · doi:10.21203/rs.3.rs-3505942/v1
Modulation of humoral immunity by γδ T cells: A potential adjuvant strategy for vaccination
Emery, K., & Eberl, M. (2025) · Advances in immunology · doi:10.1016/bs.ai.2025.05.001
Defects in B Cell Survival and Activation
Akhoon, C., & Yong, P. F. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-12-824465-4.00196-4
T Follicular Helper (Tfh) Cells are a Distinct CD4 T Helper Subset
Hirsch, E. S., Brimmer, K. E., & Weinstein, J. S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-12-824465-4.00281-7
Follicular helper T cells and fibrotic diseases
Ma, Y., Zhou, Y., & Yu, M. (2025) · Cellular Immunology · doi:10.1016/j.cellimm.2025.105024
T follicular helper cell development during malaria
Antonetti, R. M., Shah, M., & Butler, N. S. (2025) · Current Opinion in Immunology · doi:10.1016/j.coi.2025.102682
Lenalidomide targets the T-cell co-stimulatory pathway to mediate immune modulation
McDaniel, J. M. (2012) · Digital Commons - University of South Florida (University of South Florida)
Role of Interleukin 21 in CD4 T cell regulation
Attridge, K. (2012) · University of Birmingham Institutional Research Archive (University of Birmingham)
Halsen sin forsvarsstyrke: Tonsillane og kampen mot luftvegsinfeksjonar
Brokstad, K. A., & Nundal, C. H. (2025) · Naturen · doi:10.18261/naturen.149.4.7
Analyse des altérations oncogéniques associées aux lymphomes NK/T de type nasal
Huang, Y.-L. (2009) · theses.fr (ABES) · doi:10.70675/ecdb81e7z8c9cz4f26zafdazf1d0747d96e3
Implication de ROQUIN dans la physiopathologie du lymphome T angio-immunoblastique
Auguste, T. (2012) · theses.fr (ABES) · doi:10.70675/db1f2eeez04bez4837za71dzf7b77bc522d6
Metadata
- Authors
- Chtanova, T., Tangye, S. G., Newton, R., Frank, N., Hodge, M. R., Rolph, M. S., & Mackay, C. R.
- Affiliations
- The University of Sydney (AU)
- Centenary Institute (AU)
- Garvan Institute of Medical Research (AU)
- Takeda Oncology (United States) (US)
- Corresponding author
- Chtanova, Tatyana
- Newton, Rebecca
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-07-01
- Volume
- 173
- Issue
- 1
- Pages
- 68-78
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W2113687173
- Cited by
- 722
- References
- 64
- Citations by year
- 2026: 9 · 2025: 17 · 2024: 7 · 2023: 21 · 2022: 22 · 2021: 23 · 2020: 30 · 2019: 31 · 2018: 25 · 2017: 33 · 2016: 35 · 2015: 37 · 2014: 43 · 2013: 43 · 2012: 64
- FWCI
- 8.87
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Journal of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Medical Research Council
- National Health and Medical Research Council
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Keywords
- T follicular helper cells, gene expression profiling, CXCR5, CXCL13, Th1/Th2 paradigm, B cell help, humoral immunity, CD84, CD200, IL-21, BCL6, T cell differentiation, secondary lymphoid organs
- MeSH terms
- Signaling Lymphocytic Activation Molecule Family, Interleukin-21, B-Lymphocytes, DNA-Binding Proteins, T-Lymphocytes, Helper-Inducer, Humans, Interleukins, Proto-Oncogene Proteins, Transcription Factors, Antigens, CD, Receptors, Cytokine, CD57 Antigens, Receptors, Chemokine, Gene Expression Profiling, Proto-Oncogene Proteins c-bcl-6, Receptors, CXCR5
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review