A Review of Existing Treatments for Substance abuse among the Elderly and Recommendations for Future Directions
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Background: With population aging, there is widespread recognition that the healthcare system must be prepared to serve the unique needs of substance using older adults (OA) in the decades ahead. As such, there is an increasingly urgent need to identify efficient and effective substance abuse treatments (SAT) for OA. Despite this need, there remains a surprising dearth of research on treatment for OA. Aims of review: This review describes and evaluates studies on SAT applied to and specifically designed for OA over the last 30 years with an emphasis on methodologies used and the knowledge gained. Methods: Using three research databases, 25 studies published in the last 30 years which investigated the impact of SAT on OA and met specific selection criteria were reviewed. Results: A majority of the studies were methodologically limited in that they were pre-to-post or post-test only studies. Of the randomized controlled trials, many were limited by sample sizes of 15 individuals or less per group, making main effects difficult to detect. Thus, with caution, the literature suggests that among treatment seeking OA, treatment, whether age-specific or mixed-age, generally works yielding rates of abstinence comparable to general populations and younger cohorts. It also appears that with greater treatment exposure (higher dosage), regardless of level of care, OA do better. Finally, based on only two studies, age-specific treatment appears to potentiate treatment effects for OA. Like younger adults, OA appear to have a heterogeneous response to treatments, and preliminary evidence suggests a possibility of treatment matching for OA. Conclusions: Expansion of research on SAT for OA is urgently needed for maximum effectiveness and efficiency of the healthcare system serving these individuals. Future research needs to include laboratory and community based randomized controlled trials with high internal validity of previously vetted evidenced-based practices, including Motivational Interviewing, cognitive behavioral therapy, and medications such as naltrexone, to determine the best fit for OA.
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Naltrexone is the most well-studied medication for substance use disorder treatment among older adults and has demonstrated effectiveness with this population.
“Naltrexone is the most well‐studied medication used for substance use disorder treatment among older adults, and it has demonstrated effectiveness with this population.”
From Mental health care for older adults: recent advances and new directions in clinical practice and research (2022) · cites this paper as [311]
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- Authors
- Kuerbis, A., & Sacco, P.
- Affiliations
- Columbia University Irving Medical Center (US)
- University of Maryland, School of Social Work.
- Corresponding author
- Kuerbis, Alexis
- Venue
- Substance Abuse: Research and Treatment
- Publisher
- SAGE Publications
- Published
- 2013-01
- Volume
- 7
- Pages
- 13-37
- ISSN
- 1178-2218 (ISSN-L)
- PMC
- PMC3583444
- OpenAlex
- W2162087584
- Cited by
- 98
- References
- 91
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 6 · 2023: 2 · 2022: 12 · 2021: 7 · 2020: 8 · 2019: 6 · 2018: 9 · 2017: 11 · 2016: 10 · 2015: 7 · 2014: 9 · 2013: 1
- FWCI
- 6.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Substance Abuse Research and Treatment (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Columbia Academic Commons (Columbia University)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- addiction treatment, older adults, age-specific treatment, treatment response heterogeneity, treatment matching, abstinence rates, treatment dosage, randomized controlled trials, population aging, motivational interviewing, cognitive behavioral therapy, naltrexone, evidence-based practice
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