The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
mRNP granules: Assembly, function, and connections with disease
Open accessAbstract
Messenger ribonucleoprotein (mRNP) granules are dynamic, self-assembling structures that harbor non-translating mRNAs bound by various proteins that regulate mRNA translation, localization, and turnover. Their importance in gene expression regulation is far reaching, ranging from precise spatial-temporal control of mRNAs that drive developmental programs in oocytes and embryos, to similarly exquisite control of mRNAs in neurons that underpin synaptic plasticity, and thus, memory formation. Analysis of mRNP granules in their various contexts has revealed common themes of assembly, disassembly, and modes of mRNA regulation, yet new studies continue to reveal unexpected and important findings, such as links between aberrant mRNP granule assembly and neurodegenerative disease. Continued study of these enigmatic structures thus promises fascinating new insights into cellular function, and may also suggest novel therapeutic strategies in various disease states.
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mRNA localization: Gene expression in the spatial dimension
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P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
Eulalio, A., Behm-Ansmant, I., Schweizer, D., & Izaurralde, E. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00128-07 · Cited by 710
Lithium delays progression of amyotrophic lateral sclerosis
Fornai, F., Longone, P., Cafaro, L., Kastsiuchenka, O., Ferrucci, M., Manca, M. L., Lazzeri, G., Spalloni, A., Bellio, N., Lenzi, P., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708022105 · Cited by 550
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Yang, P., Mathieu, C., Kolaitis, R.-M., Zhang, P., Messing, J., Yurtsever, U., Yang, Z., Wu, J., Li, Y., Pan, Q., et al. (2020) · Cell · doi:10.1016/j.cell.2020.03.046 · Cited by 1,249
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Wheeler, J. R., Matheny, T., Jain, S., Abrisch, R., & Parker, R. (2016) · eLife · doi:10.7554/elife.18413 · Cited by 804
RNA transport and local translation in neurodevelopmental and neurodegenerative disease
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Metadata
- Authors
- Buchan, J. R.
- Venue
- RNA Biology
- Publisher
- Informa UK Limited
- Published
- 2014-08-03
- Volume
- 11
- Issue
- 8
- Pages
- 1019-1030
- ISSN
- 1547-6286 (ISSN-L)
- 1555-8584
- OpenAlex
- W2073910361
- Cited by
- 459
- References
- 5
- FWCI
- 14.11
- Type
- journal article
- Language
- en
- Status
- Retracted
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
