The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Assembly and disassembly of the nucleolus during the cell cycle
Open accessAbstract
The nucleolus is a large nuclear domain in which transcription, maturation and assembly of ribosomes take place. In higher eukaryotes, nucleolar organization in three sub-domains reflects the compartmentation of the machineries related to active or inactive transcription of the ribosomal DNA, ribosomal RNA processing and assembly with ribosomal proteins of the two (40S and 60S) ribosomal subunits. The assembly of the nucleoli during telophase/early G(1) depends on pre-existing machineries inactivated during prophase (the transcription machinery and RNP processing complexes) and on partially processed 45S rRNAs inherited throughout mitosis. In telophase, the 45S rRNAs nucleate the prenucleolar bodies and order the dynamics of nucleolar assembly. The assembly/disassembly processes of the nucleolus depend on the equilibrium between phosphorylation/dephosphorylation of the transcription machinery and on the RNP processing complexes under the control of the CDK1-cyclin B kinase and PP1 phosphatases. The dynamics of assembly/disassembly of the nucleolus is time and space regulated.
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Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis
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The Nucleolus and Ribosome Biogenesis
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Synthesis of RNA and protein during mitosis in mammalian tissue culture cells
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Orchestrating nuclear envelope disassembly and reassembly during mitosis
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The nucleolus: an old factory with unexpected capabilities
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Cited by
The nucleolus as a multiphase liquid condensate
Lafontaine, D. L. J., Riback, J. A., Bascetin, R., & Brangwynne, C. P. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0272-6 · Cited by 1,051
Imaging-based pooled CRISPR screening reveals regulators of lncRNA localization
Wang, C., Lu, T., Emanuel, G., Babcock, H. P., & Zhuang, X. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1903808116 · Cited by 111
“RNAs can be localized to cellular compartments formed by phase separation via two mechanisms (20): (i) RNAs can act as a scaffold, which could facilitate the nucleation of phase separation, such as mRNAs in P body and stress granules (49) and preribosome RNAs in nucleoli (50), and (ii) RNAs can be recruited to the pha…”
BackgroundMapping the invisible chromatin transactions of prophase chromosome remodeling
Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G., & Earnshaw, W. C. (2022) · Molecular Cell · doi:10.1016/j.molcel.2021.12.039 · Cited by 21
Conserved nucleolar stress at the onset of cell death
Golstein, P. (2017) · The FEBS Journal · doi:10.1111/febs.14095 · Cited by 7
Metadata
- Authors
- Hernandez-Verdun, D.
- Venue
- Nucleus
- Publisher
- Informa UK Limited
- Published
- 2011-05
- Volume
- 2
- Issue
- 3
- Pages
- 189-194
- ISSN
- 1949-1034 (ISSN-L)
- 1949-1042
- OpenAlex
- W2024368545
- Cited by
- 310
- References
- 58
- FWCI
- 5.88
- Type
- journal article
- Language
- en
- Open access
- hybrid
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