The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.
The potential of nitric oxide releasing therapies as antimicrobial agents
Open accessAbstract
Nitric oxide (NO) is a short-lived, diatomic, lipophilic gas that plays an integral role in defending against pathogens. Among its many functions are involvement in immune cell signaling and in the biochemical reactions by which immune cells defend against bacteria, fungi, viruses and parasites. NO signaling directs a broad spectrum of processes, including the differentiation, proliferation, and apoptosis of immune cells. When secreted by activated immune cells, NO diffuses across cellular membranes and exacts nitrosative and oxidative damage on invading pathogens. These observations led to the development of NO delivery systems that can harness the antimicrobial properties of this evanescent gas. The innate microbicidal properties of NO, as well as the antimicrobial activity of the various NO delivery systems, are reviewed.
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1 retracted
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Cited by
The metabolic signature of macrophage responses
Viola, A., Munari, F., Sánchez-Rodríguez, R., Scolaro, T., & Castegna, A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01462 · Cited by 2,021
Nitric oxide synthase in innate and adaptive immunity: an update
Bogdan, C. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.01.003 · Cited by 862
Alternative Antimicrobial Approach: Nano-Antimicrobial Materials
Beyth, N., Houri-Haddad, Y., Domb, A., Khan, W., & Hazan, R. (2015) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2015/246012 · Cited by 837
Wo, Y., Brisbois, E. J., Bartlett, R. H., & Meyerhoff, M. E. (2016) · Biomaterials Science · doi:10.1039/c6bm00271d · Cited by 251
Nitric oxide–releasing macromolecular scaffolds for antibacterial applications
Yang, L., Feura, E. S., Ahonen, M. J. R., & Schoenfisch, M. H. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201800155 · Cited by 218
Metadata
- Authors
- Schairer, D. O., Chouake, J. S., Nosanchuk, J. D., & Friedman, A. J.
- Venue
- Virulence
- Publisher
- Informa UK Limited
- Published
- 2012-05
- Volume
- 3
- Issue
- 3
- Pages
- 271-279
- ISSN
- 2150-5594 (ISSN-L)
- 2150-5608
- OpenAlex
- W1991597890
- Cited by
- 573
- References
- 102
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- gold
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- Schairer, D. O., Chouake, J. S., Nosanchuk, J. D., & Friedman, A. J. (2012). The potential of nitric oxide releasing therapies as antimicrobial agents. Virulence. https://doi.org/10.4161/viru.20328
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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