Role of chemokines and chemokine receptors in prostate cancer development and progression.
Open accessAbstract
Prostate cancer (PC) is the second leading cause of cancer deaths in men in America and Western Europe. Epidemiological studies suggest that prostate cancer incidences increased in last few years in Asian. The causes or consequences of increasing trend of prostate cancer incidence are not completely known. Emerging evidences suggest that among the many risk factors, inflammation is the major risk factor for developing prostate cancer and its progression to metastasis. It is proposed that exposure to environmental factors such as infectious agents, dietary agents and saturated lipids leads to injury of the prostate due to chronic inflammation and regenerative risk factor lesions referred to as proliferative inflammatory atrophy (PIA). These phenomena predominantly control by a number of proinflammatory macro molecules such as chemokines, and their receptors. Some recent studies suggest that many of these pro-inflammatory chemokines and their receptors are the products of protooncogenes in many cancers including that of the prostate. This review will focus on the current biology of chemokines and chemokine receptors in prostate cancer. An understanding of this axis may enable researchers to develop targeted strategies for prostate cancer.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Chronic local inflammation in the prostate (proliferative inflammatory atrophy) can promote up-regulation of inflammatory signaling factors that can drive the development and progression of prostate tumors.
“Chronic local inflammation in the prostate (proliferative inflammatory atrophy) can promote up-regulation of inflammatory signaling factors that can drive the development and progression of prostate tumors.”
From Minireview: Alternative Activation Pathways for the Androgen Receptor in Prostate Cancer (2011) · cites this paper as [16]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Jemal, A., Siegel, R. L., Ward, E., Hao, Y., Xu, J., Murray, T., & Thun, M. J. (2008) · CA A Cancer Journal for Clinicians · doi:10.3322/ca.2007.0010 · Cited by 10,184 · see citing works
Screening and Prostate-Cancer Mortality in a Randomized European Study
Schröder, F. H., Hugosson, J., Roobol, M. J., Tammela, T. L. J., Ciatto, S., Nelen, V., KWIATKOWSKI, M. K., Lujan, M., Lilja, H. G., Zappa, M., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810084 · Cited by 4,016 · see citing works
Zlotnik, A., & Yoshie, O. (2000) · Immunity · doi:10.1016/s1074-7613(00)80165-x · Cited by 3,859 · see citing works
The Biology of Chemokines and their Receptors
Rossi, D., & Zlotnik, A. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.217 · Cited by 2,410 · see citing works
Inflammation in prostate carcinogenesis
Marzo, A. M. D., Platz, E. A., Sutcliffe, S. S., Xu, J., Grönberg, H., Drake, C. G., Nakai, Y., Isaacs, W. B., & Nelson, W. G. (2007) · Nature reviews. Cancer · doi:10.1038/nrc2090 · Cited by 1,615 · see citing works
Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes
Sallusto, F., Lenig, D., Mackay, C. R., & Lanzavecchia, A. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.6.875 · Cited by 1,535 · see citing works
Gerard, C., & Rollins, B. J. (2001) · Nature Immunology · doi:10.1038/84209 · Cited by 1,357 · see citing works
Burns, J. M., Summers, B. C., Wang, Y., Melikian, A., Berahovich, R., Miao, Z., Penfold, M. E. T., Sunshine, M. J., Littman, D. R., Kuo, C. J., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20052144 · Cited by 1,264 · see citing works
Chemokines and Cell Migration in Secondary Lymphoid Organs
Cyster, J. G. (1999) · Science · doi:10.1126/science.286.5447.2098 · Cited by 1,029 · see citing works
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone.
Taichman, R. S., Cooper, C. R., Keller, E. T., Pienta, K. J., Taichman, N. S., & McCauley, L. K. (2002) · PubMed · Cited by 994 · see citing works
Mechanisms of normal and tumor-derived angiogenesis
Papetti, M., & Herman, I. M. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00389.2001 · Cited by 809 · see citing works
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
Brat, D. J., Bellail, A. C., & Meir, E. G. V. (2005) · Neuro-Oncology · doi:10.1215/s1152851704001061 · Cited by 760 · see citing works
Potosky, A. L., Davis, W. W., Hoffman, R. M., Stanford, J. L., Stephenson, R. A., Penson, D. F., & Harlan, L. C. (2004) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djh259 · Cited by 680 · see citing works
Human prostate cancer risk factors
Bostwick, D. G., BURKE, H. B., Djakiew, D., Euling, S. Y., Ho, S., Landolph, J. R., MORRISON, H. I., Sonawane, B. R., Shifflett, T., Waters, D. J., et al. (2004) · Cancer · doi:10.1002/cncr.20408 · Cited by 644 · see citing works
Osteoblasts in prostate cancer metastasis to bone
Logothetis, C. J., & Lin, S.-H. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1528 · Cited by 613 · see citing works
Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality
Tsai, H. K., D'Amico, A. V., Sadetsky, N., Chen, M., & Carroll, P. R. (2007) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm168 · Cited by 520 · see citing works
Giovannucci, E. L., Liu, Y., Platz, E. A., Stampfer, M. J., & Willett, W. C. (2007) · International Journal of Cancer · doi:10.1002/ijc.22788 · Cited by 513 · see citing works
Wallace, T. A., Prueitt, R. L., Yi, M., Howe, T. M., Gillespie, J. W., Yfantis, H. G., Stephens, R. M., Caporaso, N. E., Loffredo, C. A., & Ambs, S. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-2608 · Cited by 512 · see citing works
Hendrix, C. W., Flexner, C. W., MacFarland, R. T., Giandomenico, C. M., Fuchs, E. J., Redpath, E., Bridger, G. J., & Henson, G. W. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.6.1667-1673.2000 · Cited by 503 · see citing works
Ann, W. H. (2006) · Frontiers in bioscience · doi:10.2741/1891 · Cited by 447 · see citing works
Chemokines: agents for the immunotherapy of cancer?
Homey, B., Müller, A., & Zlotnik, A. (2002) · Nature Reviews Immunology · doi:10.1038/nri748 · Cited by 398 · see citing works
Hendrix, C. W., Collier, A. C., Lederman, M. M., Schols, D., Pollard, R. B., Brown, S., Jackson, J. B., Coombs, R. W., Glesby, M. J., Flexner, C. W., et al. (2004) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000137371.80695.ef · Cited by 367 · see citing works
MOLECULAR INSIGHTS INTO PROSTATE CANCER PROGRESSION: THE MISSING LINK OF TUMOR MICROENVIRONMENT
Chung, L. W. K., Baseman, A. G., Assikis, V. J., & Zhau, H. E. (2005) · The Journal of Urology · doi:10.1097/01.ju.0000141582.15218.10 · Cited by 358 · see citing works
Vicari, A. P., & Caux, C. (2002) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(01)00033-8 · Cited by 351 · see citing works
Azenshtein, E., Luboshits, G., Shina, S., Neumark, E., Shahbazian, D., Weil, M., Wigler, N., Keydar, I., & Ben‐Baruch, A. (2002) · PubMed · Cited by 335 · see citing works
Homey, B., Wang, W., Soto, H., Buchanan, M. E., Wiesenborn, A., Catron, D., Müller, A., McClanahan, T. K., Dieu‐Nosjean, M., Orozco, R., et al. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.7.3465 · Cited by 332 · see citing works
Activation of PI3K‐Akt signaling pathway promotes prostate cancer cell invasion
Shukla, S., MacLennan, G. T., Hartman, D. J., Fu, P., Resnick, M. I., & Gupta, S. (2007) · International Journal of Cancer · doi:10.1002/ijc.22862 · Cited by 316 · see citing works
Inflammation in benign prostatic hyperplasia: A 282 patients' immunohistochemical analysis
Robert, G., Descazeaud, A., Nicolaı̈ew, N., Terry, S., Sirab, N., Vacherot, F., Maillé, P., Allory, Y., & TAILLE, A. D. L. (2009) · The Prostate · doi:10.1002/pros.21027 · Cited by 279 · see citing works
Interleukin-8 Is a Molecular Determinant of Androgen Independence and Progression in Prostate Cancer
Araki, S., Omori, Y., Lyn, D. A., Singh, R. K., Meinbach, D. M., Sandman, Y., Lokeshwar, V. B., & Lokeshwar, B. L. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-1162 · Cited by 275 · see citing works
Self-citationProstate-cancer mortality in the USA and UK in 1975–2004: an ecological study
Collin, S. M., Martin, R. M., Metcalfe, C. D., Gunnell, D., Albertsen, P. C., Neal, D. E., Hamdy, F. C., Stephens, P. J., Lane, J. A., Moore, R., et al. (2008) · The Lancet Oncology · doi:10.1016/s1470-2045(08)70104-9 · Cited by 272 · see citing works
Charbonnier, A.-S., Kohrgruber, N., Kriehuber, E., Stingl, G., Rot, A., & Maurer, D. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.12.1755 · Cited by 267 · see citing works
Chemokines in neoplastic progression
Zlotnik, A. (2004) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2003.10.004 · Cited by 266 · see citing works
Organ selectivity in metastasis: regulation by chemokines and their receptors
Ben‐Baruch, A. (2007) · Clinical & Experimental Metastasis · doi:10.1007/s10585-007-9097-3 · Cited by 264 · see citing works
Hermani, A., DESERVI, B., Medunjanin, S., Tessier, P. A., & Mayer, D. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2005.10.013 · Cited by 262 · see citing works
Ogawa, N., Li, P., Zhenjun, L., Takada, Y., & Sugai, S. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10577 · Cited by 214 · see citing works
Murphy, C., McGurk, M., Pettigrew, J., Santinelli, A., Roberta Mazzucchelli, A., Johnston, P. G., Montironi, R., & Waugh, D. J. J. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-1518 · Cited by 213 · see citing works
Quality of Life: Radical Prostatectomy Versus Radiation Therapy for Prostate Cancer
Lim, A. J., Brandon, A. H., Fiedler, J. A., Brickman, A. L., Boyer, C. I., Raub, W. A., & Soloway, M. S. (1995) · The Journal of Urology · doi:10.1016/s0022-5347(01)66881-2 · Cited by 212 · see citing works
Kukreja, P., Abdel‐Mageed, A. B., Mondal, D., Liu, K., & Agrawal, K. C. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1293 · Cited by 209 · see citing works
Zaballos, Á., Gutiérrez, J., Varona, R., Ardavı́n, C., & Márquez, G. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.10.5671 · Cited by 203 · see citing works
Alibhai, S. M. H., Leach, M., TOMLINSON, G. A., Krahn, M. D., Fleshner, N. E., Holowaty, E. J., & Naglie, G. (2005) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dji313 · Cited by 202 · see citing works
Distinct CXC Chemokines Mediate Tumorigenicity of Prostate Cancer Cells
Moore, B. B., Arenberg, D. A., Stoy, K., Morgan, T., Addison, C., Morris, S. B., Glass, M., Wilke, C. A., Xue, Y., Sitterding, S. M., et al. (1999) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65404-1 · Cited by 200 · see citing works
RIETBERGEN, J. B. W., Kruger, A. E. B., Ries Kranse, C., & Schröder, F. H. (1997) · Urology · doi:10.1016/s0090-4295(97)00100-3 · Cited by 199 · see citing works
Inflammation and Chronic Prostatic Diseases: Evidence for a Link?
Sciarra, A., Silverio, F. D., Salciccia, S., Gomez, A. M. A., Gentilucci, A., & Gentile, V. (2007) · European Urology · doi:10.1016/j.eururo.2007.06.038 · Cited by 196 · see citing works
Chemokines in tumor progression and metastasis
Tanaka, T. T., Bai, Z., Srinoulprasert, Y., Yang, B., Hayasaka, H., & Miyasaka, M. (2005) · Cancer Science · doi:10.1111/j.1349-7006.2005.00059.x · Cited by 190 · see citing works
Macrophages promote angiogenesis in human breast tumour spheroids in vivo
Bingle, L., Lewis, C. E., Corke, K. P., Reed, M., & Brown, N. J. (2005) · British Journal of Cancer · doi:10.1038/sj.bjc.6602901 · Cited by 190 · see citing works
Chemokine receptors and melanoma metastasis
Murakami, T., Cardones, A. R., & Hwang, S. T. (2004) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2004.03.002 · Cited by 184 · see citing works
Identification of Single C Motif-1/Lymphotactin Receptor XCR1
Yoshida, T., Imai, T., Kakizaki, M., Nishimura, M., Takagi, S., & Yoshie, O. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.26.16551 · Cited by 170 · see citing works
Chemokines in tumor angiogenesis and metastasis
Singh, S., Sadanandam, A., & Singh, R. K. (2007) · Cancer and Metastasis Reviews · doi:10.1007/s10555-007-9068-9 · Cited by 168 · see citing works
Self-citationYao, S., & Lu‐Yao, G. L. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.22.1950 · Cited by 167 · see citing works
Burger, M., Burger, J. A., Hoch, R. C., Oades, Z. G., Takamori, H., & Schraufstätter, I. U. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.4.2017 · Cited by 155 · see citing works
Denberg, T. D., Melhado, T. V., & Steiner, J. F. (2006) · Cancer · doi:10.1002/cncr.22033 · Cited by 149 · see citing works
Infection after transrectal core biopsies of the prostate
Aus, G., Ahlgren, G., Bergdahl, S., & Hugosson, J. (1996) · British Journal of Urology · doi:10.1046/j.1464-410x.1996.01014.x · Cited by 147 · see citing works
Darash-Yahana, M., Gillespie, J. W., Hewitt, S. M., Chen, Y.-Y. K., Maeda, S., Stein, I., Singh, S. P., Bedolla, R. B., Peled, A., Troyer, D. A., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006695 · Cited by 143 · see citing works
Screening and Prostate-Cancer Mortality in a Randomized European Study
Lawton, C. A. (2010) · Yearbook of Oncology · doi:10.1016/s1040-1741(09)79428-x · Cited by 138 · see citing works
Chemokine Regulation of Normal and Pathologic Immune Responses
Christopherson, K. W., & Hromas, R. (2001) · Stem Cells · doi:10.1634/stemcells.19-5-388 · Cited by 137 · see citing works
Prostatitis, Sexually Transmitted Diseases, and Prostate Cancer: The California Men's Health Study
Cheng, I. C., Witte, J. S., Jacobsen, S. J., Haque, R., Quinn, V. P., Quesenberry, C. P., Caan, B. J., & Eeden, S. K. V. D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008736 · Cited by 133 · see citing works
Hamilton, A. S., Stanford, J. L., Gilliland, F. D., Albertsen, P. C., Stephenson, R. A., Hoffman, R. M., Eley, J. W., Harlan, L. C., & Potosky, A. L. (2001) · Journal of Clinical Oncology · doi:10.1200/jco.2001.19.9.2517 · Cited by 131 · see citing works
Emerging roles of chemokines in prostate cancer
Vindrieux, D., Escobar, P., & Lazennec, G. (2009) · Endocrine Related Cancer · doi:10.1677/erc-09-0109 · Cited by 127 · see citing works
The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention
Nelson, W. G., Marzo, A. M. D., & DeWeese, T. L. (2001) · Urology · doi:10.1016/s0090-4295(00)00939-0 · Cited by 122 · see citing works
Manipulating the chemokine‐chemokine receptor network to treat cancer
Ruffini, P. A., Morandi, P., Cabıoğlu, N., Altundağ, K., & Cristofanilli, M. (2007) · Cancer · doi:10.1002/cncr.22706 · Cited by 114 · see citing works
Fowler, F. J., COLLINS, M. M., Corkery, E. W., Elliott, D. B., & Barry, M. J. (2002) · Cancer · doi:10.1002/cncr.10656 · Cited by 110 · see citing works
NE-10 Neuroendocrine Cancer Promotes the LNCaP Xenograft Growth in Castrated Mice
Jin, R. J., Wang, Y., Masumori, N., Ishii, K., Tsukamoto, T., Shappell, S. B., Hayward, S. W., Kasper, S., & Matusik, R. J. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3117 · Cited by 109 · see citing works
Amyloid Formation by the Pro-Inflammatory S100A8/A9 Proteins in the Ageing Prostate
Yanamandra, K., Alexeyev, O. A., Zamotin, V., Srivastava, V., Shchukarev, A., Brorsson, A., Tartaglia, G. G., Vogl, T., Kayed, R., Wingsle, G., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005562 · Cited by 108 · see citing works
Singh, R. K., & Lokeshwar, B. L. (2009) · Molecular Cancer · doi:10.1186/1476-4598-8-57 · Cited by 105 · see citing works
Self-citationUehara, H., Troncoso, P., Johnston, D. A., Bucana, C. D., Dinney, C. P., Dong, Z., Fidler, I. J., & Pettaway, C. A. (2005) · The Prostate · doi:10.1002/pros.20223 · Cited by 97 · see citing works
Chemokine-Chemokine Receptor Network in Immune Cell Trafficking
Kim, C. H. (2004) · Current Drug Targets - Immune Endocrine & Metabolic Disorders · doi:10.2174/1568008043339712 · Cited by 95 · see citing works
CCR11 Is a Functional Receptor for the Monocyte Chemoattractant Protein Family of Chemokines
Schweickart, V. L., Epp, A., Raport, C. J., & Gray, P. W. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9550 · Cited by 94 · see citing works
CXCL12 G801A Polymorphism Is a Risk Factor for Sporadic Prostate Cancer Susceptibility
Hirata, H., Hinoda, Y., Kikuno, N., Kawamoto, K., Dahiya, A. V., Suehiro, Y., Tanaka, Y., & Dahiya, R. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-0859 · Cited by 94 · see citing works
The role of inflammation and infection in the pathogenesis of prostate carcinoma
Wagenlehner, F. R. A., Elkahwaji, J. E., Ferran Algaba, B., Johansen, T. E. B., Naber, K. G., Härtung, R., & Weidner, W. (2007) · British Journal of Urology · doi:10.1111/j.1464-410x.2007.07091.x · Cited by 86 · see citing works
Inflammation and Prostate Cancer
Vasto, S., Carruba, G., Candore, G., Italiano, E., Bona, D. D., & Caruso, C. (2008) · Future Oncology · doi:10.2217/14796694.4.5.637 · Cited by 80 · see citing works
Brachytherapy for Prostate Cancer: A Systematic Review
Koukourakis, G. V., Kelekis, N., Armonis, V., & Kouloulias, V. (2009) · Advances in Urology · doi:10.1155/2009/327945 · Cited by 76 · see citing works
Multi-faceted roles for CXC-chemokines in prostate cancer progression
Waugh, D. J. J. (2008) · Frontiers in bioscience · doi:10.2741/3025 · Cited by 58 · see citing works
Jongsma, J., Oomen, M. H., Noordzij, M. A., van Weerden, W. M., Martens, G. J. M., van der Kwast, T., Schröder, F. H., & van Steenbrugge, G. J. (2002) · The Prostate · doi:10.1002/pros.10049 · Cited by 57 · see citing works
The “Emigration, Migration, and Immigration” of Prostate Cancer
Pienta, K. J., & Loberg, R. D. (2005) · Clinical Prostate Cancer · doi:10.3816/cgc.2005.n.008 · Cited by 57 · see citing works
Mazur, D. J., & Merz, J. F. (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb01863.x · Cited by 51 · see citing works
Sexually Transmitted Diseases and Sexual Function
Sadeghi‐Nejad, H., Wasserman, M., Weidner, W., Richardson, D., & Goldmeier, D. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01622.x · Cited by 50 · see citing works
New insights into the role of CXCR4 in prostate cancer metastasis
Gladson, C. L., & Welch, D. R. (2008) · Cancer Biology & Therapy · doi:10.4161/cbt.7.11.7218 · Cited by 42 · see citing works
Angiogenesis Inhibition in Prostate Cancer: Current Uses and Future Promises
Aragon‐Ching, J. B., Madan, R. A., & Dahut, W. L. (2010) · Journal of Oncology · doi:10.1155/2010/361836 · Cited by 33 · see citing works
Androgen receptor abnormalities in castration-recurrent prostate cancer.
Nacusi, L. P., & Tindall, D. J. (2009) · Expert Review of Endocrinology & Metabolism · doi:10.1586/eem.09.34 · Cited by 27 · see citing works
Civenni, G., & Sommer, L. (2008) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2008.11.003 · Cited by 11 · see citing works
Jongsma, J., Oomen, M. H., Noordzij, M. A., et al. (2002) · The Prostate · doi:10.1002/pros.10049.abs · Cited by 5 · see citing works
[Expressions of bacterial 16S rRNA, IL-1beta, TNF-alpha and NGF in prostate tissues].
Xie, H., Huang, H., Yang, Y.-R., He, Q.-X., Zhu, Q.-J., & Chen, J.-O. (2010) · PubMed · Cited by 3 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Koukourakis G, Kelekis N, Armonis V, Kouloulias V (2009) Brachytherapy for prostatecancer: a systematic review. Adv Urol 2009: 327945.
Cited by
Sorted by citations
Minireview: Alternative Activation Pathways for the Androgen Receptor in Prostate Cancer
Lamont, K. R., & Tindall, D. J. (2011) · Molecular Endocrinology · doi:10.1210/me.2010-0469 · Cited by 150 · see citing works
Zeig‐Owens, R., Webber, M. P., Hall, C. B., Schwartz, T. M., Jaber, N., Weakley, J., Rohan, T. E., Cohen, H. W., Derman, O., Aldrich, T. K., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60989-6 · Cited by 139 · see citing works
Epigenetic Regulation of Inflammatory Cytokines and Associated Genes in Human Malignancies
Yasmin, R., Siraj, S., Hassan, A., Khan, A. R., Abbasi, R., & Ahmad, N. (2015) · Mediators of Inflammation · doi:10.1155/2015/201703 · Cited by 118 · see citing works
Kuo, P., Shen, K., Hung, S., & Hsu, Y. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs299 · Cited by 103 · see citing works
Lu, Y., Dong, B., Xu, F., Xu, Y., Pan, J., Song, J., Zhang, J., Huang, Y., & Xue, W. (2019) · Cell Communication and Signaling · doi:10.1186/s12964-019-0434-3 · Cited by 93 · see citing works
A high‐fat diet enhances proliferation of prostate cancer cells and activates MCP‐1/CCR2 signaling
Huang, M., Narita, S., Numakura, K., Tsuruta, H., Saito, M., Inoue, T., Horikawa, Y., Tsuchiya, N., & Habuchi, T. (2012) · The Prostate · doi:10.1002/pros.22531 · Cited by 68 · see citing works
Chemokines and Chemokine Receptors as Promoters of Prostate Cancer Growth and Progression
Salazar, N., Castellan, M. A., Shirodkar, S. S., & Lokeshwar, B. L. (2013) · Critical Reviews in Eukaryotic Gene Expression · doi:10.1615/critreveukaryotgeneexpr.2013006905 · Cited by 67 · see citing works
Self-citationZhuo, C., Wu, X., Li, J., Hu, D., Jian, J., Chen, C., Zheng, X., & Yang, C. (2018) · Bioscience Reports · doi:10.1042/bsr20180580 · Cited by 56 · see citing works
Miao, L., Holley, A. K., Zhao, Y., Clair, W. H. S., & Clair, D. K. S. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2013.5637 · Cited by 41 · see citing works
Chen, K., Wu, K., Jiao, X., Wang, L., Ju, X., Wang, M., Sante, G. D., Xu, S., Wang, Q., Li, K., et al. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-0611 · Cited by 39 · see citing works
Han, I., Kim, J., Jang, K., & Ryu, J. (2019) · The Prostate · doi:10.1002/pros.23826 · Cited by 38 · see citing works
Manna, S., Singha, B., Phyo, S. A., Gatla, H. R., Chang, T., Sanacora, S., Ramaswami, S., & Vancurova, I. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300895 · Cited by 32 · see citing works
The Osteoblastic and Osteoclastic Interactions in Spinal Metastases Secondary to Prostate Cancer
Dushyanthen, S., Cossigny, D. A. F., & Quan, G. M. Y. (2013) · Cancer Growth and Metastasis · doi:10.4137/cgm.s12769 · Cited by 29 · see citing works
Molecular determinants of prostate cancer metastasis
Rycaj, K., & Tang, D. G. (2017) · Oncotarget · doi:10.18632/oncotarget.21085 · Cited by 27 · see citing works
Somatostatin receptors as a new active targeting sites for nanoparticles
Abdellatif, A. A. H., Aldalaen, S., Faisal, W., & Tawfeek, H. M. (2018) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2018.05.014 · Cited by 26 · see citing works
Zhu, H., & Garcia, J. A. (2013) · Current Oncology Reports · doi:10.1007/s11912-013-0300-1 · Cited by 25 · see citing works
Antioxidant Treatment Promotes Prostate Epithelial Proliferation in Nkx3.1 Mutant Mice
Martinez, E. E., Anderson, P. D., Logan, M., & Abdulkadir, S. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046792 · Cited by 25 · see citing works
Taguchi, Y. (2015) · BMC Bioinformatics · doi:10.1186/1471-2105-16-s18-s16 · Cited by 23 · see citing works
Sex steroid-induced DNA methylation changes and inflammation response in prostate cancer
Wang, S., Clarke, P. A. G., Davis, R., Mumuni, S., & Kwabi‐Addo, B. (2016) · Cytokine · doi:10.1016/j.cyto.2016.07.006 · Cited by 22 · see citing works
Role of Tumor Suppressor Protein p53 in Apoptosis and Cancer Therapy
Naga Deepthi, C. H., Kumar, V. P., babu, R., & darshini, U. I. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-001 · Cited by 20 · see citing works
CXCL12-CXCR4/CXCR7 axis contributes to cell motilities of oral squamous cell carcinoma
Chen, N., Jiang, X. Y., Wang, J., Wu, T., Cheng, B., & Xia, J. (2015) · Tumor Biology · doi:10.1007/s13277-015-3803-6 · Cited by 20 · see citing works
Salman, H., Bergman, M., Blumberger, N., Djaldetti, M., & Bessler, H. (2013) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2013.12.007 · Cited by 15 · see citing works
Biomarkers and their Role in Premonition, Interpretation and Treatment of Cancer
Sai, Y. R. K. M., Dattatreya, A., Anand, S. Y., & Mahalakshmi, D. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-002 · Cited by 11 · see citing works
Extensive serum cytokine analysis in patients with prostate cancer
Gong, D., Wang, Y., Wang, Y., Chen, X., Chen, S., Wang, R., Liu, L., Duan, C., & Luo, S. (2019) · Cytokine · doi:10.1016/j.cyto.2019.154810 · Cited by 10 · see citing works
Immuno Defense Mechanism against Tumors
Naga Anusha, P., Siddiqui, A., & Hima Bindu, A. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-005 · Cited by 8 · see citing works
Epigenetic Changes of the Immune System with Role in Tumor Development
Florea, I. D., & Karaoulani, C. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8751-1_11 · Cited by 6 · see citing works
Chang, K., Chen, S., Hsu, S.-Y., Sung, H., Lin, W.-Y., Tsui, K.-H., Lin, Y., Hou, C., & Juang, H. (2024) · Antioxidants · doi:10.3390/antiox13121489 · Cited by 4 · see citing works
The Influence of Environmental and Genetic Factors on Various Disorders and Diseases
Tripathy, K., & Nanda, T. (2011) · Journal of Genetic Syndromes & Gene Therapy · doi:10.4172/2157-7412.s11-001 · Cited by 4 · see citing works
Epigenetic and Therapeutic Analysis of various Neurological Disorders
Tripathy, K. (2011) · Journal of Genetic Syndromes & Gene Therapy · doi:10.4172/2157-7412.1000111 · Cited by 3 · see citing works
Epidemiology and Treatment for Thyroid Cancer
Srilatha, B., Hima Bindu, A., & Soumya, D. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-011 · Cited by 3 · see citing works
Latini, G., Felice, C. D., Barducci, A., Dipaola, L., Gentile, M., Andreassi, M. G., Correale, M., & Bianciardi, G. (2018) · Cancer Biomarkers · doi:10.3233/cbm-170050 · Cited by 3 · see citing works
Organ Specific Cancers - Recent Advances in Diagnosis and Treatment
Shalini, G., Remya, R. S., Gayathri, G., & Vishalakshi, V. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-006 · Cited by 2 · see citing works
Significance of Dietary Antioxidants in Averting Cancer
Subrahmanyam, V. V., & Ramachandran, R. P. (2012) · Journal of Carcinogenesis & Mutagenesis · doi:10.4172/2157-2518.1000127 · Cited by 2 · see citing works
Quantitative Analysis of Bortezomib-Induced IL-8 Gene Expression in Ovarian Cancer Cells
Singha, B., Phyo, S. A., Gatla, H. R., & Vancurova, I. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-0928-5_27 · Cited by 2 · see citing works
A Compendium of Cancer Therapeutic Strategies and their Modality
Lakshmi Prasanna, N., & Sathish Kumar, D. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-010 · Cited by 1 · see citing works
Part of Tumor Suppressor Protein p53 in Apoptosis and Cancer Therapy
Tripathi, V. (2015) · Research and reviews : journal of medical and health sciences/Research an reviews : journal of medical and health sciences · Cited by 1 · see citing works
Lu, M. (2013) · UKnowledge (University of Kentucky)
Inflamación y cáncer de próstata: implicaciones biológicas y posible utilidad clínica
Reyes, N., & Correa, O. (2013) · IATREIA · doi:10.17533/udea.iatreia.15143
Vaccine Potentiality and Stem Cells Enhancing Cure to Cancer
Parthasarathi, D., & Palki, D. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-008
An Eye on Breast and Prostate Cancers
Gandi, S., Phaneendra, M., Anamika, K., & Jyothi, J. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.s17-003
The Impact of Environmental and Genetic Factors on different Disorders and Diseases
Tripathi, V. (2015) · Research and Reviews: Journal of Microbiology and Biotechnology
Biomarkers and their Role in Premonition, Elucidation and Treatment of Cancer
Tripathi, V. (2015) · Research and reviews : journal of medical and health sciences/Research an reviews : journal of medical and health sciences
Genetic Effect and Environmental Analysis of Various Genetic Diseases
Tripathy, K. (2015) · Research and reviews : journal of medical and health sciences/Research an reviews : journal of medical and health sciences
- Authors
- Singh, R. K., Sudhakar, A., & Lokeshwar, B. L.
- Affiliations
- University of Miami (US)
- Creighton University (US)
- United States Department of Veterans Affairs (US)
- Venue
- Journal of Cancer Science & Therapy
- Publisher
- OMICS Publishing Group
- Published
- 2010
- Volume
- 02
- Issue
- 04
- Pages
- 89-94
- ISSN
- 1948-5956 (ISSN-L)
- OpenAlex
- W2045135900
- Cited by
- 45
- References
- 81
- Citations by year
- 2024: 1 · 2019: 3 · 2018: 4 · 2017: 1 · 2016: 1 · 2015: 9 · 2014: 1 · 2013: 9 · 2012: 4
- FWCI
- 3.96
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Cancer Science & Therapy (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Flight Attendant Medical Research Institute
- National Cancer Institute (R01CA143128)
- Topics
- Health Sciences › Medicine › Oncology › Chemokine receptors and signaling
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Prostate Cancer Treatment and Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Protease and Inhibitor Mechanisms
- Keywords
- prostate cancer, chemokines, chemokine receptors, tumor progression, inflammation, proliferative inflammatory atrophy, metastasis, proto-oncogenes, risk factors, targeted therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review