Common phenotype in patients with both food and substance dependence: Case reports
Open accessAbstract
The understanding that genes play a significant role in reward dependence and associated behavioral and drug addictions is highlighted in the emergence of Reward Deficiency Syndrome (RDS). Here we show two case reports that unequivocally indicate the definite commonality between food and drug addiction. These human cases not atypically raise the question as to how to treat these two seemingly diverse addictions. We suggest that research directed in an attempt to induce natural activation of dopaminergic reward circuitry as a form of common therapy may indeed be parsimonious.
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Dysregulation of dopamine function is important for reward-related processes driving substance-seeking behavior.
“Convergence from neuroscience findings with case reports from the field have made clear that dysregulation of DA function is important for reward-related processes driving substance-seeking behavior [84].”
From Separating the Signal from the Noise: How Psychiatric Diagnoses Can Help Discern Food Addiction from Dietary Restraint (2020) · cites this paper as [84]
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- Authors
- HB, C.
- Venue
- Journal of Genetic Syndromes & Gene Therapy
- Publisher
- OMICS Publishing Group
- Published
- 2013
- Volume
- 04
- Issue
- 01
- ISSN
- 2157-7412 (ISSN-L)
- PMC
- PMC3609947
- OpenAlex
- W2148686625
- Cited by
- 8
- References
- 20
- Citations by year
- 2020: 1 · 2018: 2 · 2017: 1 · 2015: 3 · 2014: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Genetic Syndromes & Gene Therapy (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01AA007112, K05AA000219)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- reward deficiency syndrome, food addiction, substance dependence, drug addiction, addiction treatment
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