A Novel, Multi-Parallel, Real-Time Polymerase Chain Reaction Approach for Eight Gastrointestinal Parasites Provides Improved Diagnostic Capabilities to Resource-Limited At-Risk Populations

Hookworm Infection

Hotez, P. J., BROOKER, S. J., Bethony, J. M., Bottazzi, M. E., Loukas, A. C., & Shuhua, X. (2004) · New England Journal of Medicine · doi:10.1056/nejmra032492 · Cited by 627 · see citing works

Enteric infections, diarrhea, and their impact on function and development

Petri, W. A., Miller, M. A., Binder, H. J., Levine, M. M., Dillingham, R., & Guerrant, R. L. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34005 · Cited by 484 · see citing works

Capacity of Nine Thermostable DNA Polymerases To Mediate DNA Amplification in the Presence of PCR-Inhibiting Samples

Al‐Soud, W. A., & Rådström, P. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.10.3748-3753.1998 · Cited by 386 · see citing works

Experimental Human Infections with Giardia lamblia

Nash, T. E., Herrington, D. A., Losonsky, G. A., & Levine, M. M. (1987) · The Journal of Infectious Diseases · doi:10.1093/infdis/156.6.974 · Cited by 296 · see citing works

Cryptosporidiosis-associated mortality following a massive waterborne outbreak in Milwaukee, Wisconsin.

Hoxie, N. J., Davis, J. P., Vergeront, J. M., Nashold, R. D., & Blair, K. A. (1997) · American Journal of Public Health · doi:10.2105/ajph.87.12.2032 · Cited by 219 · see citing works

A Pentaplex Real-Time Polymerase Chain Reaction Assay for Detection of Four Species of Soil-Transmitted Helminths

Basuni, M., Muhi, J., Othman, N., Verweij, J. J., Ahmad, M., Miswan, N., Rahumatullah, A., Aziz, F. A., Zainudin, N. S., & Noordin, R. (2011) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2011.10-0499 · Cited by 201 · see citing works

Rapid diagnosis of Entamoeba infection by using Entamoeba and Entamoeba histolytica stool antigen detection kits

Haque, R., Neville, L. M., Hahn, P., & Petri, W. A. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.10.2558-2561.1995 · Cited by 200 · see citing works

Fast and reliable extraction of protozoan parasite DNA from fecal specimens2

DASILVA, A., Bornay-Llinares, F. J., Moura, I. N. S., Slemenda, S. B., Tuttle, J., & Pieniążek, N. J. (1999) · Molecular Diagnosis · doi:10.1016/s1084-8592(99)80050-2 · Cited by 184 · see citing works

Inclusion of polyvinylpyrrolidone in the polymerase chain reaction reverses the inhibitory effects of polyphenolic contamination of RNA

Koonjul, P. K., Brandt, W. F., Lindsey, G. G., & Farrant, J. M. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.3.915 · Cited by 173 · see citing works

Enzyme Immunoassay Detection of Immunoglobulin M and G Antibodies to Cryptosporidium in Immunocompetent and Immunocompromised Persons

Ungar, B. L. P., Soave, R., Fayer, R., & Nash, T. E. (1986) · The Journal of Infectious Diseases · doi:10.1093/infdis/153.3.570 · Cited by 161 · see citing works

Prospective Case‐Control Study of the Association between Common Enteric Protozoal Parasites and Diarrhea in Bangladesh

Haque, R., Mondal, D., Karim, A., Molla, I. H., Rahim, A., Faruque, A. S. G., Ahmad, N., Kirkpatrick, B. D., Houpt, E. R., Snider, C. J., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/597580 · Cited by 158 · see citing works

Molecular diagnostics of intestinal parasites in returning travellers

ten Hove, R.-J., Esbroeck, M. V., Vervoort, T., den Ende, J. V., van Lieshout, L., & Verweij, J. J. (2009) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-009-0745-1 · Cited by 146 · see citing works

Improved Diagnosis of Strongyloides stercoralis Using Recombinant Antigen-Based Serologies in a Community-Wide Study in Northern Argentina

Krolewiecki, A. J., Ramanathan, R., Fink, V. I., McAuliffe, I., Cajal, S. P., Won, K. Y., Juaréz, M., Paolo, A. D., Tapia, L., Acosta, N., et al. (2010) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00259-10 · Cited by 146 · see citing works

Amebic colitis: New insights into pathogenesis and treatment

Bercu, T. E., Petri, W. A., & Behm, B. W. (2007) · Current Gastroenterology Reports · doi:10.1007/s11894-007-0054-8 · Cited by 127 · see citing works

Albendazole as a treatment for infections with Giardia duodenalis in children in Bangladesh

Hall, A., & Nahar, Q. (1993) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(93)90435-s · Cited by 109 · see citing works

Real-Time PCR Method for Detection of Encephalitozoon intestinalis from Stool Specimens

Wolk, D. M., Schneider, S. K., Wengenack, N. L., Sloan, L. M., & Rosenblatt, J. E. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.11.3922-3928.2002 · Cited by 108 · see citing works

Diagnosis of Amebic Liver Abscess and Amebic Colitis by Detection of Entamoeba histolytica DNA in Blood, Urine, and Saliva by a Real-Time PCR Assay

Haque, R., Kabir, M., Noor, Z., Rahman, S. M. M., Mondal, D., Alam, F., Rahman, I., Mahmood, A. A., Ahmed, N., & Petri, W. A. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.00152-10 · Cited by 96 · see citing works

Enlarging the “Audacious Goal”: Elimination of the world's high prevalence neglected tropical diseases

Hotez, P. J. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.06.024 · Cited by 77 · see citing works

Comparison of Six Commercial DNA Extraction Kits for Recovery of Cytomegalovirus DNA from Spiked Human Specimens

Fahle, G. A., & Fischer, S. H. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.10.3860-3863.2000 · Cited by 75 · see citing works

A Real-Time PCR Method for Quantifying Viable Ascaris Eggs Using the First Internally Transcribed Spacer Region of Ribosomal DNA

Pecson, B. M., Barrios, J. A., Johnson, D. R., & Nelson, K. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01983-06 · Cited by 72 · see citing works

New approaches to the treatment of giardiasis

Tejman-Yarden, N., & Eckmann, L. (2011) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e32834ad401 · Cited by 56 · see citing works

Impact of early life exposures to geohelminth infections on the development of vaccine immunity, allergic sensitization, and allergic inflammatory diseases in children living in tropical Ecuador: the ECUAVIDA birth cohort study

Cooper, P. J., Chico, M. E., Guadalupe, I., Sandoval, C., Mitre, E. E. S., Platts‐Mills, T. A. E., Barreto, M. L., Rodrigues, L. C., Strachan, D. P., & Griffin, G. E. (2011) · BMC Infectious Diseases · doi:10.1186/1471-2334-11-184 · Cited by 48 · see citing works

Detection of selected intestinal helminths and protozoa at Hospital Universiti Sains Malaysia using multiplex real-time PCR.

Basuni, M., Mohamed, Z., Ahmad, M., Zakaria, N. Z., & Noordin, R. (2012) · PubMed · Cited by 29 · see citing works

Helminth infection is associated with decreased basophil responsiveness in human beings

LARSON, D. L., Cooper, P. J., Hübner, M. P., Reyes, J., Vaca, M. G., Chico, M. E., Kong, H. H., & Mitre, E. E. S. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.04.017 · Cited by 27 · see citing works

Protozoan parasites that infect the gastrointestinal tract

Petri, W. A. (2000) · Current Opinion in Gastroenterology · doi:10.1097/00001574-200001000-00004 · Cited by 12 · see citing works

Enzyme immunoassay for the detection ofGiardia lamblia

Carlson, J., Sullivan, P. S., Harry, D. J., Stork, M. A., Thorton, S. A., & DuPont, H. L. (1988) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/bf01962610 · Cited by 12 · see citing works

Soil-transmitted helminth infections

Jourdan, P. M., Lamberton, P. H. L., Fenwick, A., & Addiss, D. G. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31930-x · Cited by 1,034 · see citing works

Human infection with Strongyloides stercoralis and other related Strongyloides species

Nutman, T. B. (2016) · Parasitology · doi:10.1017/s0031182016000834 · Cited by 352 · see citing works

Whipworm and roundworm infections

Else, K. J., Keiser, J., Holland, C. V., Grencis, R. K., Sattelle, D. B., Fujiwara, R. T., Bueno, L. L., Asaolu, S. O., Sowemimo, O. A., & Cooper, P. J. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0171-3 · Cited by 308 · see citing works

Molecular Testing for Clinical Diagnosis and Epidemiological Investigations of Intestinal Parasitic Infections

Verweij, J. J., & Stensvold, C. R. (2014) · Clinical Microbiology Reviews · doi:10.1128/cmr.00122-13 · Cited by 230 · see citing works

Application of a Multiplex Quantitative PCR to Assess Prevalence and Intensity Of Intestinal Parasite Infections in a Controlled Clinical Trial

Llewellyn, S., Inpankaew, T., Nery, S. V., Gray, D. J., Verweij, J. J., Clements, A., Gomes, S. J., Traub, R. J., & McCarthy, J. S. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004380 · Cited by 217 · see citing works

Strongyloidiasis

Krolewiecki, A. J., & Nutman, T. B. (2019) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2018.10.006 · Cited by 202 · see citing works

Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming

Easton, A. V., Oliveira, R. G., O’Connell, E. M., Kepha, S., Mwandawiro, C. S., Njenga, S. M., Kihara, J. H., Mwatele, C., Odiere, M. R., BROOKER, S. J., et al. (2016) · Parasites & Vectors · doi:10.1186/s13071-016-1314-y · Cited by 198 · see citing works

Cryptosporidium: parasite and disease

Cacciò, S. M., & Widmer, G. (2013) · Springer eBooks · doi:10.1007/978-3-7091-1562-6 · Cited by 170 · see citing works

Rapid diagnosis of parasitic diseases: current scenario and future needs

Momčilović, S., Cantacessi, C., Arsić-Arsenijević, V. S., Otranto, D., & Otašević, S. (2018) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2018.04.028 · Cited by 171 · see citing works

Advances in understanding Giardia: Determinants and mechanisms of chronic sequelae

Bartelt, L. A., & Sartor, R. B. (2015) · F1000Prime Reports · doi:10.12703/p7-62 · Cited by 154 · see citing works

Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama

McKenna, M. L., McAtee, S., Bryan, P. E., Jeun, R., Ward, T. L., Kraus, J., Bottazzi, M. E., Hotez, P. J., Flowers, C. C., & Mejía, R. (2017) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.17-0396 · Cited by 153 · see citing works

Improved PCR-Based Detection of Soil Transmitted Helminth Infections Using a Next-Generation Sequencing Approach to Assay Design

Pilotte, N., Papaiakovou, M., Grant, J. R., Bierwert, L. A., Llewellyn, S., McCarthy, J. S., & Williams, S. A. (2016) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004578 · Cited by 150 · see citing works

Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection

Yooseph, S., Kirkness, E. F., Tran, T. M., Harkins, D. M., Jones, M. B., Torralba, M., O’Connell, E. M., Nutman, T. B., Doumbo, S., Doumbo, O. K., et al. (2015) · BMC Genomics · doi:10.1186/s12864-015-1819-3 · Cited by 131 · see citing works

Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures

Ngwese, M. M., Manouana, G. P., Moure, P. A. N., Ramharter, M., Esen, M., & Adégnika, A. A. (2020) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed5020093 · Cited by 127 · see citing works

Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted helminths in three endemic countries

Cools, P., Vlaminck, J., Albonico, M., Ame, S., Ayana, M., Barrios, J. A., Cringoli, G., Dana, D. D., Keiser, J., Maurelli, M. P., et al. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007446 · Cited by 111 · see citing works

Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana

Hansen, M. E. B., Rubel, M. A., Bailey, A. G., Ranciaro, A., Thompson, S. R., Campbell, M. C., Beggs, W., Dave, J. R., Mokone, G. G., Mpoloka, S. W., et al. (2019) · Genome Biology · doi:10.1186/s13059-018-1616-9 · Cited by 110 · see citing works

Molecular Diagnostics for Soil-Transmitted Helminths

O’Connell, E. M., & Nutman, T. B. (2016) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.16-0266 · Cited by 108 · see citing works

Molecular Epidemiology of Giardia, Blastocystis and Cryptosporidium among Indigenous Children from the Colombian Amazon Basin

Sánchez, A., Muñoz, M., Gómez, N., Tabares, J. H., Segura, L. M., Salazar, Á. S., Restrepo, C. A., Ruiz, M. Á., Reyes, P., Qian, Y., et al. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00248 · Cited by 105 · see citing works

Diagnosing Polyparasitism in a High-Prevalence Setting in Beira, Mozambique: Detection of Intestinal Parasites in Fecal Samples by Microscopy and Real-Time PCR

Meurs, L., Polderman, A. M., Melchers, N. V. S. V., Brienen, E. A. T., Verweij, J. J., Groosjohan, B., Mendes, F., Mechendura, M., Hepp, D. H., Langenberg, M. C. C., et al. (2017) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0005310 · Cited by 102 · see citing works

Human Ascariasis: Diagnostics Update

Lamberton, P. H. L., & Jourdan, P. M. (2015) · Current Tropical Medicine Reports · doi:10.1007/s40475-015-0064-9 · Cited by 101 · see citing works

Disruptions of Host Immunity and Inflammation by Giardia Duodenalis: Potential Consequences for Co-Infections in the Gastro-Intestinal Tract

Cotton, J. A., Amat, C., & Buret, A. G. (2015) · Pathogens · doi:10.3390/pathogens4040764 · Cited by 98 · see citing works

Improved diagnosis of Trichuris trichiura by using a bead-beating procedure on ethanol preserved stool samples prior to DNA isolation and the performance of multiplex real-time PCR for intestinal parasites

Kaisar, M. M. M., Brienen, E. A. T., Djuardi, Y., Sartono, E., Yazdanbakhsh, M., Verweij, J. J., Supali, T., & van Lieshout, L. (2017) · Parasitology · doi:10.1017/s0031182017000129 · Cited by 93 · see citing works

DNA Diagnostics for Schistosomiasis Control

Weerakoon, K., Gordon, C. A., & McManus, D. P. (2018) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed3030081 · Cited by 93 · see citing works

Identification of human intestinal parasites affecting an asymptomatic peri-urban Argentinian population using multi-parallel quantitative real-time polymerase chain reaction

Cimino, R. O., Jeun, R., Juaréz, M., Cajal, P. S., Vargas, P. A., Echazú, A., Bryan, P. E., Nasser, J. R., Krolewiecki, A. J., & Mejía, R. (2015) · Parasites & Vectors · doi:10.1186/s13071-015-0994-z · Cited by 92 · see citing works

Is real-time PCR-based diagnosis similar in performance to routine parasitological examination for the identification of Giardia intestinalis , Cryptosporidium parvum / Cryptosporidium hominis and Entamoeba histolytica from stool samples? Evaluation of a new commercial multiplex PCR assay and literature review

Laude, A., Valot, S., Désoubeaux, G., Argy, N., Nourrisson, C., Pomares-Estran, C., Machouart, M., Govic, Y. L., Dalle, F., Botterel, F., et al. (2015) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2015.10.019 · Cited by 92 · see citing works

Lifestyle and the presence of helminths is associated with gut microbiome composition in Cameroonians

Rubel, M., Abbas, A. A., Taylor, L. J., Connell, A. J., Tanes, C., Bittinger, K. L., Ndze, V. N., Fonsah, J. Y., Ngwang, E., Essiane, A., et al. (2020) · Genome biology · doi:10.1186/s13059-020-02020-4 · Cited by 93 · see citing works

The intestinal protozoa

Turkeltaub, J. A., McCarty, T. R., & Hotez, P. J. (2014) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000135 · Cited by 86 · see citing works

Molecular and descriptive epidemiology of intestinal protozoan parasites of children and their pets in Cauca, Colombia: a cross-sectional study

Villamizar, X., Higuera, A., Herrera, G., Arteaga, L. R. V., Buitrón-Caicedo, L., Muñoz, L. M., Gonzalez-C, F. E., López, M. C., Forero, J. C. G., & Ramírez, J. D. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-3810-0 · Cited by 85 · see citing works

The Global State of Helminth Control and Elimination in Children

Weatherhead, J. E., Hotez, P. J., & Mejía, R. (2017) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2017.03.005 · Cited by 84 · see citing works

Application of PCR-based methods for diagnosis of intestinal parasitic infections in the clinical laboratory

Verweij, J. J. (2014) · Parasitology · doi:10.1017/s0031182014000419 · Cited by 79 · see citing works

Worm Infections in Children

Weatherhead, J. E., & Hotez, P. J. (2015) · Pediatrics in Review · doi:10.1542/pir.36-8-341 · Cited by 76 · see citing works

The increased sensitivity of qPCR in comparison to Kato-Katz is required for the accurate assessment of the prevalence of soil-transmitted helminth infection in settings that have received multiple rounds of mass drug administration

Dunn, J. C., Papaiakovou, M., Han, K. T., Chooneea, D., Bettis, A. A., Wyine, N. Y., Lwin, A. M. M., Maung, N. S., Misra, R., Littlewood, D. T. J., et al. (2020) · Parasites & Vectors · doi:10.1186/s13071-020-04197-w · Cited by 73 · see citing works

Blastocystis subtyping and its association with intestinal parasites in children from different geographical regions of Colombia

Ramírez, J. D., Flórez, C., Olivera, M. J., Bernal, M. C., & Forero, J. C. G. (2017) · PLoS ONE · doi:10.1371/journal.pone.0172586 · Cited by 71 · see citing works

Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright, J. E., Werkman, M., Dunn, J. C., & Anderson, R. M. (2018) · Parasites & Vectors · doi:10.1186/s13071-018-2656-4 · Cited by 70 · see citing works

Multiplex real-time PCR monitoring of intestinal helminths in humans reveals widespread polyparasitism in Northern Samar, the Philippines

Gordon, C. A., McManus, D. P., Acosta, L. P., Olveda, R. M., Williams, G. M., Ross, A. G., Gray, D. J., & Gobert, G. N. (2015) · International Journal for Parasitology · doi:10.1016/j.ijpara.2015.02.011 · Cited by 69 · see citing works

Effects of water, sanitation, handwashing and nutritional interventions on soil-transmitted helminth infections in young children: A cluster-randomized controlled trial in rural Bangladesh

Ercümen, A., Benjamin‐Chung, J., Arnold, B. F., Lin, A., Hubbard, A., Stewart, C. P., Rahman, Z., Parvez, S. M., UNICOMB, L. E., Rahman, M. M., et al. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007323 · Cited by 69 · see citing works

Status of soil-transmitted helminth infections in schoolchildren in Laguna Province, the Philippines: Determined by parasitological and molecular diagnostic techniques

Mationg, M. L., Gordon, C. A., Tallo, V. L., Olveda, R. M., Alday, P. P., Reñosa, M. D. C., Bieri, F., Williams, G. M., Clements, A., Steinmann, P., et al. (2017) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006022 · Cited by 68 · see citing works

Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes

DiNardo, A. R., Nishiguchi, T., Mace, E. M., Rajapakshe, K., Mtetwa, G., Kay, A. W., Maphalala, G. P., Secor, W. E., Mejía, R., Orange, J. S., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800101 · Cited by 67 · see citing works

Techniques for the Diagnosis of Fasciola Infections in Animals

Rojas, C. A. Á., Jex, A. R., Gasser, R. B., & Scheerlinck, J. Y. (2014) · Advances in Parasitology/Advances in parasitology · doi:10.1016/b978-0-12-800182-0.00002-7 · Cited by 67 · see citing works

Toxocara species environmental contamination of public spaces in New York City

Tyungu, D. L., McCormick, D. W., Lau, C. L., Chang, M., Murphy, J. R., Hotez, P. J., Mejía, R., & Pollack, H. J. (2020) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0008249 · Cited by 64 · see citing works

Comparison of multi-parallel qPCR and double-slide Kato-Katz for detection of soil-transmitted helminth infection among children in rural Bangladesh

Benjamin‐Chung, J., Pilotte, N., Ercümen, A., Grant, J. R., Maasch, J. R. M. A., Gonzalez, A. M., Abrams, B. P., Ester, A. C., Arnold, B. F., Rahman, M., et al. (2020) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0008087 · Cited by 65 · see citing works

Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing

Sibandze, D. B., Kay, A. W., Dreyer, V., Sikhondze, W., Dlamini, Q., DiNardo, A. R., Mtetwa, G., Lukhele, B. W., Vambe, D., Lange, C. G., et al. (2022) · Genome Medicine · doi:10.1186/s13073-022-01054-6 · Cited by 63 · see citing works

Comparison of the egg recovery rates and limit of detection for soil-transmitted helminths using the Kato-Katz thick smear, faecal flotation and quantitative real-time PCR in human stool

Zendejas-Heredia, P. A., Colella, V., Hii, S. F., & Traub, R. J. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009395 · Cited by 61 · see citing works

Molecular diagnosis and genotype analysis of Giardia duodenalis in asymptomatic children from a rural area in central Colombia

Ramírez, J. D., Heredia, R. D., Hernández, C., León, C. M., Moncada, L. I., Reyes, P., Pinilla, A. E., & López, M. C. (2015) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2015.03.015 · Cited by 61 · see citing works

PCR for enteric pathogens in high-prevalence settings. What does a positive signal tell us?

Frickmann, H., Schwarz, N. G., Rakotozandrindrainy, R., May, J., & Hagen, R. M. (2015) · Scandinavian Journal of Infectious Diseases · doi:10.3109/23744235.2015.1022212 · Cited by 60 · see citing works

Soil-transmitted helminth reinfection four and six months after mass drug administration: results from the delta region of Myanmar

Dunn, J. C., Bettis, A. A., Wyine, N. Y., Lwin, A. M. M., Tun, A., Maung, N. S., & Anderson, R. M. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006591 · Cited by 60 · see citing works

Cryptosporidiosis in HIV/AIDS Patients in Kenya: Clinical Features, Epidemiology, Molecular Characterization and Antibody Responses

Wanyiri, J. W., Kanyi, H. M., Maina, S., Wang, D. E., Steen, A. J., Ngugi, P., Kamau, T., Waithera, T., O’Connor, R. M., Gachuhi, K., et al. (2014) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.13-0254 · Cited by 59 · see citing works

Development and Evaluation of a Multiplex Quantitative Real-Time Polymerase Chain Reaction for Hookworm Species in Human Stool

Hii, S. F., Senevirathna, D., Llewellyn, S., Inpankaew, T., Odermatt, P., Khieu, V., Muth, S., McCarthy, J. S., & Traub, R. J. (2018) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.18-0276 · Cited by 58 · see citing works

Evaluation of two DNA extraction methods for the PCR-based detection of eukaryotic enteric pathogens in fecal samples

Menu, E., Mary, C., Toga, I., Raoult, D., Ranque, S., & Bittar, F. (2018) · BMC Research Notes · doi:10.1186/s13104-018-3300-2 · Cited by 58 · see citing works

Molecular detection and genotyping of intestinal protozoa from different biogeographical regions of Colombia

Higuera, A., Villamizar, X., Herrera, G., Forero, J. C. G., Arteaga, L. R. V., Urbano, P., Villalobos, O., Tovar, C., & Ramírez, J. D. (2020) · PeerJ · doi:10.7717/peerj.8554 · Cited by 56 · see citing works

Impact of intestinal parasites on microbiota and cobalamin gene sequences: a pilot study

Mejía, R., Damania, A. V., Jeun, R., Bryan, P. E., Vargas, P. A., Juaréz, M., Cajal, P. S., Nasser, J. R., Krolewiecki, A. J., Lefoulon, E., et al. (2020) · Parasites & Vectors · doi:10.1186/s13071-020-04073-7 · Cited by 55 · see citing works

Soil-Transmitted Helminth Infections

(2022) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789811236273_0020 · Cited by 56 · see citing works

Co-infection of Long-Term Carriers of Plasmodium falciparum with Schistosoma haematobium Enhances Protection from Febrile Malaria: A Prospective Cohort Study in Mali

Doumbo, S., Tran, T. M., Sangala, J. A., Li, S., Doumtabé, D., Koné, Y., Traoré, A., Bathily, A., Sogoba, N., Coulibaly, M. E., et al. (2014) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003154 · Cited by 53 · see citing works

Prevalence, risk factors, challenges, and the currently available diagnostic tools for the determination of helminths infections in human

Riaz, M., Aslam, N., Zainab, R., Aziz-Ur-Rehman, Rasool, G., Ullah, M. I., Daniyal, M., & Akram, M. (2020) · European Journal of Inflammation · doi:10.1177/2058739220959915 · Cited by 53 · see citing works

Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a randomised controlled trial: treatment efficacy and day-to-day variation

Keller, L., Patel, C., Welsche, S., Schindler, T., Hürlimann, E., & Keiser, J. (2020) · Parasites & Vectors · doi:10.1186/s13071-020-04401-x · Cited by 47 · see citing works

Targeting a highly repeated germline DNA sequence for improved real-time PCR-based detection of Ascaris infection in human stool

Pilotte, N., Maasch, J. R. M. A., Easton, A. V., Dahlstrom, E. W., Nutman, T. B., & Williams, S. A. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007593 · Cited by 41 · see citing works

Soil-Transmitted Helminths and Anaemia: A Neglected Association Outside the Tropics

Caldrer, S., Ursini, T., Santucci, B., Motta, L., & Angheben, A. (2022) · Microorganisms · doi:10.3390/microorganisms10051027 · Cited by 45 · see citing works

More Pathogenicity or Just More Pathogens?—On the Interpretation Problem of Multiple Pathogen Detections with Diagnostic Multiplex Assays

Zautner, A. E., Groß, U., Emele, M. F., Hagen, R. M., & Frickmann, H. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01210 · Cited by 45 · see citing works

Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development

Diemert, D. J., Campbell, D., Brelsford, J., Leasure, C., Li, G., Peng, J., Zumer, M., Younes, N., Bottazzi, M. E., Mejía, R., et al. (2018) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofy083 · Cited by 44 · see citing works

Prevalence of Intestinal Parasites in a Low-Income Texas Community

Singer, R., Xu, T. H., Herrera, L. N., Villar, M. J., Faust, K. M., Hotez, P. J., Aiken, A. R. A., & Mejía, R. (2020) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.19-0915 · Cited by 43 · see citing works

Global progress towards eliminating gastrointestinal helminth infections

McCarty, T. R., Turkeltaub, J. A., & Hotez, P. J. (2013) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000025 · Cited by 42 · see citing works

Performance of Real-Time Polymerase Chain Reaction Assays for the Detection of 20 Gastrointestinal Parasites in Clinical Samples from Senegal

Sow, D., Parola, P., Sylla, K., Ndiaye, M., Delaunay, P., Halfon, P., Camiade, S., Dieng, T., Tine, R. C. K., Faye, B. T., et al. (2017) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.16-0781 · Cited by 41 · see citing works

Prevalence and risk factors for intestinal parasitic infections in pregnant women residing in three districts of Bogotá, Colombia

Espinosa, Á. F., Radon, K., Froeschl, G., Pinzón-Rondón, Á. M., & Delius, M. (2018) · BMC Public Health · doi:10.1186/s12889-018-5978-4 · Cited by 41 · see citing works

Helminth-Induced Immune Regulation: Implications for Immune Responses to Tuberculosis

Chatterjee, S., & Nutman, T. B. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1004582 · Cited by 40 · see citing works

Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador

Cooper, P. J., Chico, M. E., Platts‐Mills, T. A. E., Rodrigues, L. C., Strachan, D. P., & Barreto, M. L. (2014) · International Journal of Epidemiology · doi:10.1093/ije/dyu128 · Cited by 40 · see citing works

Testing for soil-transmitted helminth transmission elimination: Analysing the impact of the sensitivity of different diagnostic tools

Werkman, M., Wright, J. E., Truscott, J. E., Easton, A. V., Oliveira, R. G., Toor, J., Ower, A. K., Ásbjörnsdóttir, K., Means, A. R., Farrell, S. H., et al. (2018) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006114 · Cited by 38 · see citing works

Molecular detection and genotyping of pathogenic protozoan parasites in raw and treated water samples from southwest Colombia

Sánchez, C., López, M. C., Galeano, L.-A., Qvarnström, Y., Houghton, K. A., & Ramírez, J. D. (2018) · Parasites & Vectors · doi:10.1186/s13071-018-3147-3 · Cited by 38 · see citing works

High prevalence of intestinal parasite infestations among stunted and control children aged 2 to 5 years old in two neighborhoods of Antananarivo, Madagascar

Habib, A., Andrianonimiadana, L., Rakotondrainipiana, M., Andriantsalama, P., Randriamparany, R., Randremanana, R. V., Rakotoarison, R. L., Vigan-Womas, I., Rafalimanantsoa, A. S., Vonaesch, P., et al. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009333 · Cited by 37 · see citing works

Diagnostic Methods of Common Intestinal Protozoa: Current and Future Immunological and Molecular Methods

Fitri, L. E., Candradikusuma, D., Setia, Y. D., Wibawa, P. A., Iskandar, A., Winaris, N., & Pawestri, A. R. (2022) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed7100253 · Cited by 36 · see citing works

The Right Tool for the Job: Detection of Soil-Transmitted Helminths in Areas Co-endemic for Other Helminths

Periago, M. V., Diniz, R. L. F. C., Pinto, S. A., Yakovleva, A., Corrêa‐Oliveira, R., Diemert, D. J., & Bethony, J. M. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003967 · Cited by 36 · see citing works

The Role of More Sensitive Helminth Diagnostics in Mass Drug Administration Campaigns

Medley, G. F., Turner, H. C., Baggaley, R. F., Cv, H., & Hollingsworth, T. D. (2016) · Advances in Parasitology/Advances in parasitology · doi:10.1016/bs.apar.2016.08.005 · Cited by 36 · see citing works

Soil-Transmitted Helminths in the USA: a Review of Five Common Parasites and Future Directions for Avenues of Enhanced Epidemiologic Inquiry

Lynn, M. K., Morrissey, J. A., & Conserve, D. F. (2021) · Current Tropical Medicine Reports · doi:10.1007/s40475-020-00221-2 · Cited by 36 · see citing works

Advances in diagnosis of gastrointestinal nematodes in livestock and companion animals

Rinaldi, L., Krücken, J., Valladares, M. M., Pepe, P., Maurelli, M. P., de Queiroz, C., de Agüero, V. C. G., Wang, T., Cringoli, G., Charlier, J., et al. (2022) · Advances in Parasitology/Advances in parasitology · doi:10.1016/bs.apar.2022.07.002 · Cited by 35 · see citing works

Advantages and limitations of microscopy and molecular detections for diagnosis of soil-transmitted helminths: An overview

Miswan, N., Singham, G. V., & Othman, N. (2022) · Helminthologia · doi:10.2478/helm-2022-0034 · Cited by 35 · see citing works

Diagnostic and Treatment Monitoring Potential of A Stool-Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis

DiNardo, A. R., Kay, A. W., Maphalala, G. P., Harris, N. M., Fung, C., Mtetwa, G., Ustero, P., Dlamini, S., Ha, N. P., Graviss, E. A., et al. (2018) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.18-0004 · Cited by 34 · see citing works

Sources of variability in the measurement of Ascaris lumbricoides infection intensity by Kato-Katz and qPCR

Easton, A. V., Oliveira, R. G., Walker, M., O’Connell, E. M., Njenga, S. M., Mwandawiro, C. S., Webster, J. P., Nutman, T. B., & Anderson, R. M. (2017) · Parasites & Vectors · doi:10.1186/s13071-017-2164-y · Cited by 33 · see citing works

Faecal prevalence, distribution and risk factors associated with canine soil-transmitted helminths contaminating urban parks across Australia

Massetti, L., Wiethoelter, A., McDonagh, P., Rae, L., Marwedel, L., Beugnet, F., Colella, V., & Traub, R. J. (2022) · International Journal for Parasitology · doi:10.1016/j.ijpara.2022.08.001 · Cited by 34 · see citing works

Neglected tropical disease (NTD) diagnostics: current development and operations to advance control

Oyeyemi, O. T., Ogundahunsi, O. A. T., Schunk, M., Fatem, R. G., & Shollenberger, L. M. (2023) · Pathogens and Global Health · doi:10.1080/20477724.2023.2272095 · Cited by 32 · see citing works

Hookworm infection is associated with decreased CD4+ T cell counts in HIV-infected adult Ugandans

Morawski, B. M., Miya, Y., Kerukadho, E., Turyasingura, G., Barbra, L., Ojok, A. M., DiNardo, A. R., Sowinski, S., Boulware, D. R., & Mejía, R. (2017) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0005634 · Cited by 31 · see citing works

Spirorchiidiasis in marine turtles: the current state of knowledge

Chapman, P. A., Cribb, T. H., Flint, M., Traub, R. J., Blair, D., Kyaw-Tanner, M. T., & Mills, P. C. (2019) · Diseases of Aquatic Organisms · doi:10.3354/dao03348 · Cited by 31 · see citing works

Quantitative PCR in soil-transmitted helminth epidemiology and control programs: Toward a universal standard

Cools, P., Vlaminck, J., Verweij, J. J., & Levecke, B. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009134 · Cited by 31 · see citing works

Prevalence and associated risk factors of intestinal parasites among schoolchildren in Ecuador, with emphasis on the molecular diversity of Giardia duodenalis, Blastocystis sp. and Enterocytozoon bieneusi

Veloz, E. C. T., Gozalbo, M., Guillén, M., Dashti, A., Bailo, B., Köster, P. C., Santı́n, M., Carmena, D., & Trelis, M. (2023) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0011339 · Cited by 30 · see citing works

Strongyloides Stercoralis Infection Among Human Immunodeficiency Virus (HIV)-Infected Patients in the United States of America: A Case Report and Review of Literature

Guillamet, L. J. V., Saul, Z. K., Miljkovich, G., Vilchez, G., Mendonca, N. P., Gourineni, V. C., Lillo, N., Pinto, M. M., Baig, A., & Gangcuangco, L. M. A. (2017) · American Journal of Case Reports · doi:10.12659/ajcr.902626 · Cited by 29 · see citing works

What does soil-transmitted helminth elimination look like? Results from a targeted molecular detection survey in Japan

the DeWorm3 Project Team, Hasegawa, M., Pilotte, N., Kikuchi, M., Means, A. R., Papaiakovou, M., Gonzalez, A. M., Maasch, J. R. M. A., Ikuno, H., Sunahara, T., et al. (2020) · Parasites & Vectors · doi:10.1186/s13071-019-3875-z · Cited by 29 · see citing works

Clinical helminthiases in Thailand border regions show elevated prevalence levels using qPCR diagnostics combined with traditional microscopic methods

Adisakwattana, P., Yoonuan, T., Phuphisut, O., Poodeepiyasawat, A., Homsuwan, N., Gordon, C. A., McManus, D. P., Atkinson, L. E., Mousley, A., & Gobert, G. N. (2020) · Parasites & Vectors · doi:10.1186/s13071-020-04290-0 · Cited by 29 · see citing works

Comparison of Cytokine Responses in Ecuadorian Children Infected with Giardia, Ascaris, or Both Parasites

Weatherhead, J. E., Arévalo‐Cortes, A., Sandoval, C. A., Vaca, M. G., Chico, M. E., Loor, S., Cooper, P. J., & Mejía, R. (2017) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.16-0580 · Cited by 29 · see citing works

Surveillance of intestinal schistosomiasis during control: a comparison of four diagnostic tests across five Ugandan primary schools in the Lake Albert region

Al‐Shehri, H., Koukounari, A., Stanton, M. C., Adriko, M., Arinaitwe, M., Atuhaire, A., Kabatereine, N. B., & Stothard, J. R. (2018) · Parasitology · doi:10.1017/s003118201800029x · Cited by 29 · see citing works

Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study

Kay, A. W., Vasiliu, A., Carratalá-Castro, L., Mtafya, B., Reyes, J. E. M., Maphalala, N., Munguambe, S., Mulengwa, D., Ness, T. E., Saavedra, B., et al. (2024) · The Lancet Microbe · doi:10.1016/s2666-5247(23)00391-9 · Cited by 28 · see citing works

The Influence of the Protozoan Giardia lamblia on the Modulation of the Immune System and Alterations in Host Glucose and Lipid Metabolism

Klimczak, S., Packi, K., Rudek, A., Wenclewska, S., Kurowski, M. M., Kurczabińska, D., & Śliwińska, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168627 · Cited by 37 · see citing works

An extensive burden of giardiasis associated with intestinal schistosomiasis and anaemia in school children on the shoreline of Lake Albert, Uganda

Al‐Shehri, H., Stanton, M. C., LaCourse, E. J., Atuhaire, A., Arinaitwe, M., Wamboko, A., Adriko, M., Kabatereine, N. B., & Stothard, J. R. (2016) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1093/trstmh/trw072 · Cited by 28 · see citing works

Seroprevalence of Strongyloides stercoralis and Evaluation of Universal Screening in Kidney Transplant Candidates: A Single-Center Experience in Houston (2012–2017)

Al‐Obaidi, M. M., Hasbun, R., Vigil, K. J., Edwards, A. R., Chávez, V., Hall, D. R., Dar, W. A., Golovine, A. M. D., Ostrosky‐Zeichner, L., Bynon, J. S., et al. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz172 · Cited by 28 · see citing works

Quantitative PCR and Digital PCR for Detection ofAscaris lumbricoidesEggs in Reclaimed Water

Acosta, L., Santísima‐Trinidad, A. B., Bornay-Llinares, F. J., González, M. M., Pascual, J. A., & Ros, M. (2017) · BioMed Research International · doi:10.1155/2017/7515409 · Cited by 28 · see citing works

Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective

Mutombo, P. N., Man, N. W. Y., Nejsum, P. L., Ricketson, R., Gordon, C. A., Robertson, G. J., Clements, A., Chacón-Fonseca, N., Nissapatorn, V., Webster, J. P., et al. (2019) · Advances in Parasitology/Advances in parasitology · doi:10.1016/bs.apar.2019.02.004 · Cited by 27 · see citing works

Recent advances in nucleic acid-based methods for detection of helminth infections and the perspective of biosensors for future development

Ullah, H., Qadeer, A., Rashid, M., Rashid, I., & Cheng, G. (2019) · Parasitology · doi:10.1017/s0031182019001665 · Cited by 27 · see citing works

Important Nematodes in Children

Veesenmeyer, A. F. (2021) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2021.08.005 · Cited by 27 · see citing works

Development and validation of a multiplexed-tandem qPCR tool for diagnostics of human soil-transmitted helminth infections

Stracke, K., Clarke, N. E., Awburn, C. V., Nery, S. V., Khieu, V., Traub, R. J., & Jex, A. R. (2019) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0007363 · Cited by 25 · see citing works

Diagnóstico molecular de parasitosis intestinales

Dacal, E., Köster, P. C., & Carmena, D. (2020) · Enfermedades Infecciosas y Microbiología Clínica · doi:10.1016/j.eimc.2020.02.005 · Cited by 25 · see citing works

Hookworm infection in infants: a case report and review of literature

Umbrello, G., Pinzani, R., Bandera, A., Formenti, F., Zavarise, G., Arghittu, M., Girelli, D., Maraschini, A., Muscatello, A., Marchisio, P., et al. (2021) · The Italian Journal of Pediatrics/Italian journal of pediatrics · doi:10.1186/s13052-021-00981-1 · Cited by 25 · see citing works

Antimicrobial resistance of the enteric protozoon Giardia duodenalis – A narrative review

Loderstädt, U., & Frickmann, H. (2021) · European Journal of Microbiology and Immunology · doi:10.1556/1886.2021.00009 · Cited by 25 · see citing works

Harmonization of PCR-based detection of intestinal pathogens: experiences from the Dutch external quality assessment scheme on molecular diagnosis of protozoa in stool samples

Schuurs, T. A., Koelewijn, R., Brienen, E. A. T., Kortbeek, T., Mank, T. G., Mulder, B., Stelma, F. F., van Lieshout, L., & van Hellemond, J. J. (2018) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2017-1057 · Cited by 25 · see citing works

1789Multi-parallel quantitative real-time PCR surveillance of gastrointestinal parasites in a symptomatic rural Argentinian population: initial results of the Latin American Multicenter Parasite Study (LAMPS)

Mejía, R., Vargas, P. A., Jeun, R., Krolewiecki, A. J., Juaréz, M., Cajal, P. S., Nasser, J. R., Hotez, P. J., & Cimino, R. O. (2014) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofu051.161

Identification of human intestinal parasites affecting an asymptomatic peri-urban Argentinian population using multi-parallel quantitative real-time polymerase chain reaction

Cimino, R. O., Jeun, R., Juaréz, M., Cajal, P. S., Vargas, P. A., Echazú, A., Bryan, P. E., Nasser, J. R., Krolewiecki, A. J., & Mejía, R. (2015) · Parasites & Vectors · doi:10.1186/s13071-015-0994-z · Cited by 92 · see citing works

Performance of Real-Time Polymerase Chain Reaction Assays for the Detection of 20 Gastrointestinal Parasites in Clinical Samples from Senegal

Sow, D., Parola, P., Sylla, K., Ndiaye, M., Delaunay, P., Halfon, P., Camiade, S., Dieng, T., Tine, R. C. K., Faye, B. T., et al. (2017) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.16-0781 · Cited by 41 · see citing works

Multiplex Real-Time PCR Assay Targeting Eight Parasites Customized to the Korean Population: Potential Use for Detection in Diarrheal Stool Samples from Gastroenteritis Patients

Won, E. J., Kim, S. H., Kee, S., Shin, J. H., Suh, S., Chai, J.-Y., Ryang, D. W., & Shin, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166957 · Cited by 37 · see citing works

Multiplex PCR for gastrointestinal parasites in stool: Benchmarking against direct microscopy and simplex PCR

Garg, P., Bhasin, S. L., Malhotra, P., Rana, S. S., Singh, S., Sethi, J., Sehgal, R., Khurana, S., & Datta, P. (2024) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2024.116475 · Cited by 10 · see citing works