Cost-Effectiveness of a Community-Based Approach Intertwined with a Vertical Aedes Control Program
Open accessAbstract
We compared in a 5-year intervention study the cost-effectiveness of community-based environmental management intertwined with routine vertical Aedes control and of routine vertical control only. At baseline (year 2000), Aedes infestation levels and economic costs for vector control were comparable in intervention and control areas (house index, 2.23% versus 2.21% and US$21 versus US$24/yr/inhabitant, respectively). By 2004, house indices became 0.22% versus 2.36% and the costs were 29.8 US$ versus 36.7 US$/yr/inhabitant, respectively. The community cost made up 38.6% of the total economic cost in 2004 in the intervention areas against 23.5% in 2000. The average cost-effectiveness ratio for the intervention period 2001–2004, expressed as the societal cost incurred for the reduction (from baseline) of Aedes foci, was US$831.1 per focus in the intervention areas versus US$2,465.6 in the control areas. The intervention produced economic savings and health benefits that were sustained over the whole observation period.
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A number of randomised controlled studies have demonstrated significant impacts on vector indices, even though the methods of intervention varied considerably between the studies.
“A number of randomised controlled studies have demonstrated significant impacts on vector indices [47, 48, 73, 83, 101](Fig 5) even though the methods of intervention varied considerably between the studies.”
From Is Dengue Vector Control Deficient in Effectiveness or Evidence?: Systematic Review and Meta-analysis (2016) · cites this paper as [48]
The Discussion explicitly says, “our study was not a randomized community trial,” contrary to its inclusion among randomized controlled studies. The Abstract and Effectiveness section report reductions in Aedes infestation and foci, but those findings do not make this a randomized study. No page number is available in our copy. (LLM, conf=0.88)
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Experimental — accuracy not yet measuredCommunity-based environmental management significantly reduced the House Index (MD = -2.14; 95% CI -3.72, -0.56).
“Community-based environmental management significantly reduced the House Index: MD = -2.14 (95% CI -3.72, -0.56) [48] (S4 Fig)”
From Is Dengue Vector Control Deficient in Effectiveness or Evidence?: Systematic Review and Meta-analysis (2016) · cites this paper as [48]
Table 3 (page unavailable) reports a 2004 House Index of 0.22% in the intervention areas versus 2.36% in the control areas, a difference of -2.14 percentage points, with P < 0.001. The paper does not report the claimed 95% confidence interval (-3.72, -0.56). The intervention also combined community-based management with routine vertical Aedes control, rather than using community management alone. (LLM, conf=0.90)
Experimental — accuracy not yet measuredNineteen of the included studies provided sufficient data for inclusion in meta-analyses.
“Forty-one studies were included in the review [45–85] (S1 Table), nineteen of which reported sufficient data for inclusion in meta-analyses [46–48, 52, 54, 55, 58, 59, 66, 69, 73, 74, 76, 77, 80–83, 85].”
From Is Dengue Vector Control Deficient in Effectiveness or Evidence?: Systematic Review and Meta-analysis (2016) · cites this paper as [48]
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Cites
Dengue and Dengue Hemorrhagic Fever
Gubler, D. J. (1998) · Clinical Microbiology Reviews · doi:10.1128/cmr.11.3.480 · Cited by 4,394 · see citing works
Shediac-Rizkallah, M. C., & Bone, L. R. (1998) · Health Education Research · doi:10.1093/her/13.1.87 · Cited by 1,129 · see citing works
Focks, D. A., Brenner, R. J., Hayes, J., & Daniels, E. (2000) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2000.62.11 · Cited by 400 · see citing works
Programme costs in the economic evaluation of health interventions
Johns, B., Baltussen, R., & Hutubessy, R. (2003) · Cost Effectiveness and Resource Allocation · doi:10.1186/1478-7547-1-1 · Cited by 329 · see citing works
Heintze, C., Garrido, M. V., & Kroeger, A. (2007) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/j.trstmh.2006.08.007 · Cited by 238 · see citing works
Community involvement in the control of Aedes aegypti
Gubler, D. J., & Clark, G. G. (1996) · Acta Tropica · doi:10.1016/0001-706x(95)00103-l · Cited by 237 · see citing works
Bossert, T. J. (1990) · Social Science & Medicine · doi:10.1016/0277-9536(90)90148-l · Cited by 195 · see citing works
Aedes aegyptiLarval Indices and Risk for Dengue Epidemics
Sánchez, L., Vanlerberghe, V., Alfonso, L., Marquetti, M. D. C., Guzmán, M. G., Bisset, J. A., & der Stuyft, P. V. (2006) · Emerging infectious diseases · doi:10.3201/eid1205.050866 · Cited by 195 · see citing works
Self-citationKay, B. H., Nam, V. S., Tien, T. V., Yen, N. T., Phong, T. V., Diep, V. T. B., Ninh, T. U., Bektas, A., & Aaskov, J. (2002) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2002.66.40 · Cited by 170 · see citing works
WINCH, P. J., Leontsini, E., Rigau-Pérez, J. G., Ruiz-Pérez, M., Clark, G. G., & Gubler, D. J. (2002) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2002.67.363 · Cited by 167 · see citing works
Toledo, M. E., Vanlerberghe, V., Baly, A., Ceballos, E., Valdes, L., Searret, M., Boelaert, M., & Van der Stuyft, P. (2007) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/j.trstmh.2006.03.006 · Cited by 114 · see citing works
Self-citationResults of a Community-Based Aedes Aegypti Control Program in Merida, Yucatan, Mexico
Lloyd, L. S., Winch, P., Ortega-Canto, J., & Kendall, C. (1992) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1992.46.635 · Cited by 100 · see citing works
Suaya, J. A., Shepard, D. S., Chang, M. S., Caram, M., Hoyer, S., Socheat, D., Chantha, N., & Nathan, M. B. (2007) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2007.01889.x · Cited by 99 · see citing works
Clinical Characteristics and National Economic Cost of the 2005 Dengue Epidemic in Panama
Armién, B., Suaya, J. A., Quiroz, E., Sah, B. K., Bayard, V., Marchena, L., Campos, C., & Shepard, D. S. (2008) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2008.79.364 · Cited by 93 · see citing works
Dengue 3 Epidemic, Havana, 2001
Peláez, O., Guzmán, M. G., Kourí, G., Pérez, R., Martín, J. L. S., Vázquez, S., Rosario, D., Mora-Guerra, R., Quintana, I., Bisset, J. A., et al. (2004) · Emerging infectious diseases · doi:10.3201/eid1004.030271 · Cited by 78 · see citing works
Intersectoral coordination in Aedes aegypti control. A pilot project in Havana City, Cuba
Sanchez, L., Pérez, D., Pérez, T. H. G., Sosa, T., Cruz, G., Kourí, G., Boelaert, M., & der Stuyft, P. V. (2005) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2004.01347.x · Cited by 73 · see citing works
Self-citationManual de valoración contingente
Micaló, P. R. (1994) · Dialnet (Universidad de la Rioja) · Cited by 63 · see citing works
La epidemiología del dengue y del dengue hemorrágico en Santiago de Cuba, 1997
Valdés, L., Guzmán, M. G., Kourí, G., Delgado, J., Carbonell, I. T., Cabrera, M. V., Rosario, D., & Vázquez, S. (1999) · Revista Panamericana de Salud Pública · doi:10.1590/s1020-49891999000600003 · Cited by 62 · see citing works
Cost effectiveness of Aedes aegypti control programmes: participatory versus vertical
Baly, A., Toledo, M. E., Boelaert, M., Reyes, A., Vanlerberghe, V., Ceballos, E., de Carvajal, M. D. I. M., Maso, R., Rosa, M. L., Denis, O., et al. (2007) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/j.trstmh.2007.01.002 · Cited by 55 · see citing works
Self-citationNeto, F. C., de Moraes, M. S., & Fernandes, M. A. (1998) · PubMed · Cited by 54 · see citing works
International Experiences in Social Mobilization and Communication for Dengue Prevention and Control
Parks, W., Hosein, E., Prasittisuk, C., Palmer, K., Dawkins, Z., & Renganathan, E. (2004) · Cited by 46 · see citing works
Toledo-Romaní, M. E., Gil, A. B., Ceballos-Ursula, E., Boelaert, M., & der Stuyft, P. V. (2006) · Salud Pública de México · doi:10.1590/s0036-36342006000100007 · Cited by 41 · see citing works
Self-citationCaracterización final y lecciones de la epidemia de dengue 3 en Cuba, 2001-2002
Guzmán, M. G., Peláez, O., Kourí, G., Quintana, I., Vázquez, S., Pentón, M., & Ávila, L. C. (2006) · Revista Panamericana de Salud Pública · doi:10.1590/s1020-49892006000400014 · Cited by 33 · see citing works
Pai, H., Hong, Y., & Hsu, E. (2006) · PubMed · Cited by 29 · see citing works
Cost-effectiveness and financial sustainability in family planning operations research.
Er, J. (1991) · PubMed · Cited by 10 · see citing works
Wiesemann, A. H., Müller-Bühl, U., Scheidt, R., Boehme, W., & Scheuermann, W. (2004) · Sozial- und Präventivmedizin · doi:10.1007/s00038-004-3039-5 · Cited by 8 · see citing works
Haití: evolución económica durante 2003 y perspectivas para 2004
de México, N. C. S. (2004) · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Bowman, L. R., Donegan, S., & McCall, P. J. (2016) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0004551 · Cited by 449 · see citing works
“Variously, the studies investigated: clean-up campaigns in conjunction with IRS and larviciding [46]; community-based environmental management (including community-based environmental management, source reduction, larviciding, education, promote formation of CWGs, water covers) [48]; source reduction, larviciding and…”
BackgroundControl methods against invasive Aedes mosquitoes in Europe: a review
Baldacchino, F., Caputo, B., Chandre, F., Drago, A., della Torre, A., Montarsi, F., & Rizzoli, A. P. (2015) · Pest Management Science · doi:10.1002/ps.4044 · Cited by 225 · see citing works
Castro, M., Sánchez, L., Pérez, D., Carbonell, N., Lefèvre, P., Vanlerberghe, V., & Van der Stuyft, P. (2012) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/j.trstmh.2012.01.013 · Cited by 70 · see citing works
Self-citationRIZZO, N. R., Gramajo, R., Escobar, M. C., Arana, B. A., Kroeger, A., Manrique-Saide, P. C., & Petzold, M. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-931 · Cited by 62 · see citing works
Sanchez, L., Perez, D., Cruz, G., Castro, M., Kourí, G., Shkedy, Z., Vanlerberghe, V., & Van der Stuyft, P. (2009) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2009.02379.x · Cited by 58 · see citing works
Self-citationMarcos‐Marcos, J., Lima, A. O. D. L., Toro-Cárdenas, S., Lacasaña, M., Degroote, S., Ridde, V., & Bermúdez‐Tamayo, C. (2018) · Infectious Diseases of Poverty · doi:10.1186/s40249-018-0464-x · Cited by 50 · see citing works
The application of environmental management methods in combating dengue: a systematic review
Mahmud, M. A. F., Mutalip, M. H. A., Lodz, N. A., Muhammad, E. N., Yoep, N., Hasim, M. H., Rahim, F. A. A., Aik, J., Rajarethinam, J., & Muhamad, N. A. (2022) · International Journal of Environmental Health Research · doi:10.1080/09603123.2022.2076815 · Cited by 48 · see citing works
Changing paradigms in Aedes control: considering the spatial heterogeneity of dengue transmission.
Vanlerberghe, V., Gómez‐Dantés, H., Vazquez‐Prokopec, G. M., Alexander, N. D. E., Manrique-Saide, P. C., Coelho, G. E., Toledo, M. E., Ocampo, C. B., & der Stuyft, P. V. (2017) · Europe PMC (PubMed Central) · doi:10.26633/rpsp.2017.16 · Cited by 45 · see citing works
Self-citationToledo, M. E., Rodriguez, A., Valdés, L., Carrión, R., Cabrera, G., Banderas, D., Ceballos, E., Domeqc, M., Peña, C., Baly, A., et al. (2011) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2011.02762.x · Cited by 40 · see citing works
Self-citationCosts of dengue prevention and incremental cost of dengue outbreak control in Guantanamo, Cuba
Baly, A., Toledo, M. E., Rodríguez, K., Benitez, J. R., Rodriguez, M., Boelaert, M., Vanlerberghe, V., & der Stuyft, P. V. (2011) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2011.02881.x · Cited by 35 · see citing works
Self-citationIndravudh, P. P., Fielding, K., Kumwenda, M., Nzawa, R., Chilongosi, R., Desmond, N., Nyirenda, R. K., Johnson, C., Baggaley, R. C., Hatzold, K., et al. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-4430-4 · Cited by 32 · see citing works
The Cost of Routine Aedes aegypti Control and of Insecticide-Treated Curtain Implementation
Baly, A., Fleßa, S., Cote, M., Thiramanus, T., Vanlerberghe, V., Villegas, E., Jirarojwatana, S., & der Stuyft, P. V. (2011) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2011.10-0532 · Cited by 30 · see citing works
Self-citationLaboudi, M., Sahibi, H., Elabandouni, M., Nhammi, H., Hamou, S. A., & Sadak, A. (2018) · Acta Tropica · doi:10.1016/j.actatropica.2018.07.019 · Cited by 28 · see citing works
Innovative dengue vector control interventions in Latin America: what do they cost?
Alfonso-Sierra, E., Basso, C., Beltrán‐Ayala, E., Mitchell‐Foster, K., Quintero, J., Cortés, S., Manrique-Saide, P. C., Guillermo-May, G., Caprara, A., de Lima, E. C., et al. (2016) · Pathogens and Global Health · doi:10.1080/20477724.2016.1142057 · Cited by 23 · see citing works
Halasa, Y. A., Shepard, D. S., Wittenberg, E., Fonseca, D. M., Farajollahi, A., Healy, S. P., Gaugler, R. R., Strickman, D. A., & Clark, G. G. (2012) · Journal of the American Mosquito Control Association · doi:10.2987/12-6243r.1 · Cited by 22 · see citing works
Toledo, M. E., Vanlerberghe, V., Lambert, I., Montada, D., Baly, A., & der Stuyft, P. V. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119373 · Cited by 16 · see citing works
Self-citationThirty Years after the Cuban Hemorrhagic Dengue Epidemic of 1981
Guzmán, M. G. (2012) · MEDICC Review · doi:10.37757/mr2012v14.n2.11 · Cited by 16 · see citing works
Cost-effectiveness of a Dengue Vector Control Intervention in Colombia
Taborda, A., Chamorro, C., Quintero, J., Carrasquilla, G., & Londoño, D. (2022) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.20-0669 · Cited by 14 · see citing works
Cholvi-Simó, M., Moretti, R., Osório, H. C., L’Ambert, G., Seixas, G., Kavran, M., Michaelakis, Α., Stephanou, A., Antoniou, C., Martinou, A. F., et al. (2026) · Insects · doi:10.3390/insects17030254 · Cited by 12 · see citing works
Dengue in Cuba: research strategy to support dengue control
Guzmán, M. G., & Kourí, G. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61975-9 · Cited by 12 · see citing works
[Thirty years after the Cuban dengue hemorrhagic epidemic occurred in 1981].
Tirado, C. M. G. G. (2012) · PubMed · Cited by 11 · see citing works
Puerta-Guardo, H. N., & Manrique-Saide, P. C. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.98177 · Cited by 10 · see citing works
Baly, A., Gonzalez, K., Cabrera, P., Popa, J. C., Toledo, M. E., Hernandez, C., Montada, D., Vanlerberghe, V., & der Stuyft, P. V. (2016) · Tropical Medicine & International Health · doi:10.1111/tmi.12693 · Cited by 9 · see citing works
Self-citationBaly, A., Toledo, M. E., Lambert, I., Benitez, E. O., Rodríguez, K., Albarrán-Rodríguez, E., Vanlerberghe, V., & der Stuyft, P. V. (2016) · Revista da Sociedade Brasileira de Medicina Tropical · doi:10.1590/0037-8682-0368-2015 · Cited by 8 · see citing works
Self-citationAtiglo, D. Y., Larbi, R. T., Kushitor, M. K., Biney, A. A. E., Asante, P. Y., Dodoo, N. D., & Dodoo, F. N.-A. (2018) · Malaria Journal · doi:10.1186/s12936-018-2424-0 · Cited by 8 · see citing works
A Realist Synthesis of Community-Based Interventions in Vector-Borne Diseases
Pérez, D., Robert, É., Pérez, E. J., Vanlerberghe, V., Lefèvre, P., & Ridde, V. (2021) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.20-0944 · Cited by 8 · see citing works
Self-citationRodríguez-Reyes, A. J., Roncancio, C. P., & Misnaza, S. P. (2020) · Revista Médica de Risaralda · doi:10.22517/25395203.18721 · Cited by 6 · see citing works
La inequidad en salud: el caso del dengue
Vanlerberghe, V., & Verdonck, K. (2014) · Revista Peruana de Medicina Experimental y Salud Pública · doi:10.17843/rpmesp.2013.304.252 · Cited by 5 · see citing works
Self-citationPérez, D., Castro, M., Álvarez, Á. M. F., Sánchez, L., Toledo, M. E., Matos, D., der Stuyft, P. V., & Lefèvre, P. (2016) · PubMed · Cited by 5 · see citing works
Self-citationHerrera, M. M. C., García, A. F., & Lorenzo, I. S. (2011) · International Journal of Care Coordination · doi:10.1258/jicp.2011.011m30 · Cited by 4 · see citing works
Nonlinearities in transmission dynamics and efficient management of vector‐borne pathogens
Ginsberg, H. S., & Couret, J. (2019) · Ecological Applications · doi:10.1002/eap.1892 · Cited by 4 · see citing works
Gómez-Vargas, W., & Zapata-Úsuga, G. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.105026 · Cited by 3 · see citing works
Enfermedades de la pobreza, el caso del dengue
Tirado, M. G. G., Valdés, A. M. Á., González, O. F., & Flores, G. K. (2012) · Anales de la Academia de Ciencias de Cuba · Cited by 2 · see citing works
Communication Protocols in Public Health
Dwivedi, S., & Sagar, M. (2017) · Journal of Health Management · doi:10.1177/0972063417699719 · Cited by 2 · see citing works
Urban Ecology and the Effectiveness of Aedes Control
Alonso, W. J., & McCormick, B. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.78688 · Cited by 2 · see citing works
Muñóz, M., de Cuéllar, C. M., & de Assis, D. M. (2015) · Pediatría (Asunción) · doi:10.18004/ped.2015.abril.11-16
Actitudes, conocimientos y prácticas sobre el dengue y su vector en el municipio Camagüey
Mayo, M. D. J. M., Mayo, M., Bethencourt, J. A. B., Acao, L., & Ramentol, C. C. L. (2016) · Revista Archivo Médico de Camagüey
Dengue, Dengue hemorrhagic fever
Guzmán, M. G., Marqueti, M. C., Martinez, E., & Perez, A. B. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99967-0.00288-x
Abassi, M., Pourrazavi, S., Moosazadeh, M., Enayati, A., ahmadzadeh, S., Mehralinasab, G., Normandipour, F., Abolghaseminejad, P., Azimi, S., & Yousefi, S. (2026) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0013929
- Authors
- Baly, A., Toledo, M. E., Vanlerberghe, V., Ceballos, E., Reyes, A., Sanchez, I., Carvajal, M., Maso, R., La Rosa, M., Denis, O., Boelaert, M., & Van der Stuyft, P.
- Affiliations
- Instituto de Medicina Tropical “Pedro Kourí” (CU)
- Instituto de Medicina Tropical “Pedro Kourí,” Department of Epidemiology, La Habana, Cuba; Institute of Tropical Medicine, Epidemiology and Disease Control Unit, Department of Public Health, Antwerp, Belgium; Provincial Unit of Surveillance and Vector Control, Santiago de Cuba, Cuba; Instituto de Medicina Tropical “Pedro Kourí,” Department of Economics, La Habana, Cuba
- Corresponding author
- Baly, Alberto
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 2009-07
- Volume
- 81
- Issue
- 1
- Pages
- 88-93
- ISSN
- 0002-9637 (ISSN-L)
- OpenAlex
- W2131257352
- Cited by
- 40
- References
- 27
- Citations by year
- 2026: 2 · 2024: 1 · 2022: 4 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 6 · 2015: 3 · 2014: 1 · 2013: 1 · 2012: 6
- FWCI
- 4.03
- Type
- journal article
- Language
- en
- Open access
- green
- biblio.ugent.be
- Licence
- other-oa
- Locations
- American Journal of Tropical Medicine and Hygiene (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Mosquito-borne diseases and control
- Social Sciences › Sociology and Political Science › Dengue and Mosquito Control Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Keywords
- community-based environmental management, house index, mosquito breeding sites, cost-effectiveness ratio, community participation, vector-borne disease prevention
- MeSH terms
- Aedes, Animals, Community Health Services, Cost-Benefit Analysis, Costs and Cost Analysis, Mosquito Control
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