Ability of Lactobacillus and Propionibacterium Strains to Remove Aflatoxin B1 from the Chicken Duodenum
Open accessAbstract
The ability of Lactobacillus rhamnosus strains GG and LC-705 to remove AFB1 from the intestinal luminal liquid medium has been tested in vivo using a chicken intestinal loop technique. In this study, the GG strain of L. rhamnosus decreased AFB1 concentration by 54% in the soluble fraction of the luminal fluid within 1 min. This strain was more efficient in binding AFB1 compared with L. rhamnosus strain LC-705 (P < 0.05) that removed 44% of AFBl under similar conditions. Accumulation of AFB1 into the intestinal tissue was also determined. There was a 74% reduction in the uptake of AFB1 by the intestinal tissue, in the presence of L. rhamnosus strain GG compared with 63% and 37% in the case of Propionibacterium freudenreichii ssp. shermanii JS and L. rhamnosus strain LC-705, respectively. The complexes formed in vitro between either L. rhamnosus strain GG or L. rhamnosus strain LC-705 and AFB1 were stable under the luminal conditions for a period of 1 h.
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Trials to limit absorption of mycotoxins using probiotic LAB are in the research phase, although there are reports of reductions in AFB1 in the gastrointestinal tract of chickens.
“So far, these trials are in the research phase, although there are reports of reductions in AFB1 in the gastrointestinal tract of chickens (El-Nezami et al. 2000).”
From Trends in designing microbial silage quality by biotechnological methods using lactic acid bacteria inoculants: a minireview. (2019) · cites this paper as El-Nezami et al. 2000
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Mechanisms of Aflatoxin Carcinogenesis
Eaton, D. L., & Gallagher, E. P. (1994) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.34.040194.001031 · Cited by 773 · see citing works
Ability of dairy strains of lactic acid bacteria to bind a common food carcinogen, aflatoxin B1
El-Nezami, H. S., Kankaanpää, P., Salminen, S., & Ahokas, J. T. (1998) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(97)00160-9 · Cited by 464 · see citing works
Self-citationEllis, W. O., Smith, J. P., Simpson, B. K., et al. (1991) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408399109527551 · Cited by 342 · see citing works
El-Nezami, H. S., Kankaanpää, P., Salminen, S., & Ahokas, J. T. (1998) · Journal of Food Protection · doi:10.4315/0362-028x-61.4.466 · Cited by 209 · see citing works
Self-citationAflatoxins in Animal and Human Health
Robens, J. F., & Richard, J. L. (1992) · Reviews of Environmental Contamination and Toxicology · doi:10.1007/978-1-4613-9751-9_3 · Cited by 208 · see citing works
Determination of Complement-Mediated Killing of Bacteria by Viability Staining and Bioluminescence
Virta, M., Lineri, S., Kankaanpää, P., et al. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.2.515-519.1998 · Cited by 116 · see citing works
Self-citationIntestinal absorption and excretion of aflatoxin in rats
Kumagai, S. (1989) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(89)90057-4 · Cited by 67 · see citing works
Biologic Control of Food Carcinogens with Use of Lactobacillus GG
El-Nezami, H. S., Salminen, S., & Ahokas, J. T. (1996) · Nutrition Today · doi:10.1097/00017285-199611001-00013 · Cited by 25 · see citing works
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Research works printed but not linked: 2
- Hsieh, P. H., and J. J. Wong. 1994. Pharmacokinetics and excretion of aflatoxins, p. 73-88. In D. L. Eaton and J. D. Groopman (ed.), The toxicology of aflatoxins: human health, veterinary, and agricultural significance. Academic Press, San Diego, Calif.
- Rodricks, J. V., and L. Stoloff. 1977. Aflatoxin residues from contam- inated feed in edible tissues of food producing animals, p. 75-89. In J. V. Rodricks, C. W. Hesseltine, and M. A. Mehlman (ed.), Myco- toxins in human and animal health. Pathotox. Publ., Park Forest South, Ill.
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Detoxification of patulin and ochratoxin A, two abundant mycotoxins, by lactic acid bacteria
Fuchs, S., Sontag, G., Stidl, R., Ehrlich, V., Kundi, M., & Knasmüller, S. (2008) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.10.008 · Cited by 345 · see citing works
El-Nezami, H. S., Polychronaki, N. N., Ma, J., Zhu, H., Ling, W., Salminen, E. K., Juvonen, R. O., Salminen, S. J., Poussa, T., & Mykkänen, H. M. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.5.1199 · Cited by 184 · see citing works
Self-citationNiderkorn, V., Morgavi, D. P., Pujos, E., Tissandier, A., & Boudra, H. (2007) · Food Additives and Contaminants · doi:10.1080/02652030601101110 · Cited by 126 · see citing works
Fabiszewska, A. U., Zielińska, K. J., & Wróbel, B. (2019) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-019-2649-2 · Cited by 121 · see citing works
Recent Trends in Microbiological Decontamination of Aflatoxins in Foodstuffs
Fernandes Oliveira, C. A., Bovo, F., Humberto, C., Vincenzi, A., & Ravindranadha, K. (2013) · Aflatoxins - Recent Advances and Future Prospects · doi:10.5772/51120 · Cited by 36 · see citing works
- Authors
- El-Nezami, H., Mykkänen, H., Kankaanpää, P., Salminen, S., & Ahokas, J.
- Affiliations
- RMIT University (AU)
- University of Eastern Finland (FI)
- University of Turku (FI)
- Corresponding author
- Ahokas, Jorma
- Venue
- Journal of Food Protection
- Publisher
- Elsevier BV
- Published
- 2000-04
- Volume
- 63
- Issue
- 4
- Pages
- 549-552
- ISSN
- 0362-028X (ISSN-L)
- OpenAlex
- W1567106189
- Cited by
- 210
- References
- 8
- Citations by year
- 2025: 4 · 2024: 1 · 2023: 5 · 2022: 8 · 2021: 6 · 2020: 12 · 2019: 15 · 2018: 11 · 2017: 12 · 2016: 6 · 2015: 11 · 2014: 13 · 2013: 11 · 2012: 13
- FWCI
- 5.59
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Food Protection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Keywords
- aflatoxin B1, Lactobacillus rhamnosus GG, mycotoxin binding, mycotoxin removal, intestinal loops, probiotics, aflatoxin detoxification
- MeSH terms
- Animals, Chickens, Chromatography, High Pressure Liquid, Duodenum, Lactobacillus, Propionibacterium, Aflatoxin B1
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