Potential use of ultrasound in antioxidant extraction from Ecklonia cava
Open accessAbstract
Water and methanolic extracts of Ecklonia cava, a marine brown alga, were prepared by ultrasonic extraction (UE) and conventional extraction (CE) methods.The radical-scavenging activity and the inhibitory effects against hydrogen peroxide (H 2 O 2 )-induced DNA damage of the extracts were investigated.All extracts prepared by CE exhibited higher total polyphenolic content than that in the extracts prepared by UE.Extraction yield and total phenolic content increased as the UE time increased.The radical-scavenging activities increased as the UE time increased.All extracts prepared by CE exhibited higher 1,1-diphenyl-2-pricrylhydrazyl (DPPH) and hydroxyl radical-scavenging activities than did those prepared by UE.Extracts prepared by UE showed stronger scavenging activities on alkyl radical and H 2 O 2 than those prepared by CE did.Methanolic extract with UE 12 h (100MEU-12h) and methanolic extract with CE 24 h (100MEC-24h) were selected and evaluated by comet assay for their inhibitory effect against H 2 O 2 -induced DNA damage.100MEU-12h showed slightly greater protective effect against H 2 O 2 -induced DNA damage than 100MEC-24h.Thus, UE can be effectively used as a seaweed extraction technique, and there is potential for scale-up of the extraction process.
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Available data of UAE extraction of macroalgae shows polyphenols and antioxidants are the main extracted compounds, using solvents such as ethanol, distilled water, and methanol with different solid:solvent ratios.
“Available data of UAE extraction of macroalgae shows that polyphenols and antioxidants are the main extracted compounds from macroalgae (Table 2). Various solvents were used, such as ethanol, distilled water, and methanol with different solid:solvent ratio [7,49,50].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [50]
Lee et al. compared UAE extracts with conventional method; UAE extracts showed higher yield than CE; higher amount of TPC was in CE extracts; yield and TPC are time-dependent; UAE extracts showed good radical scavenging activity and inhibitory effect against DNA damage induced by H2O2.
“Lee et al. [50] conducted much longer time of the UAE unlike other authors [49,52]. They compared the yield and the antioxidant activity of UAE extracts with the extracts that were obtained with conventional method (CE). The extracts obtained with UAE showed higher yield than those of CE. The higher amount of TPC was in the extracts obtained with CE and the results showed that the yield and TPC”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [50]
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- Authors
- Lee, S.-H., Kang, M.-C., Moon, S.-H., Jeon, B.-T., & Jeon, Y.-J.
- Affiliations
- Konkuk University (KR)
- Jeju National University (KR)
- Venue
- ALGAE
- Publisher
- The Korean Society of Phycology
- Published
- 2013-12-15
- Volume
- 28
- Issue
- 4
- Pages
- 371-378
- ISSN
- 1226-2617 (ISSN-L)
- OpenAlex
- W2143923117
- Cited by
- 48
- References
- 26
- Citations by year
- 2026: 9 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 1 · 2016: 5 · 2015: 5 · 2014: 2
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- ALGAE (publishedVersion)
- Funders
- Rural Development Administration
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Physical Sciences › Materials Science › Materials Chemistry › Ultrasound and Cavitation Phenomena
- Keywords
- Ecklonia cava, ultrasound-assisted extraction, antioxidant extraction, marine brown algae, free radical scavenging, hydrogen peroxide-induced DNA damage, polyphenols, DPPH radical, hydroxyl radicals, comet assay, extraction yield, scale-up
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