Impact of enzyme- and ultrasound-assisted extraction methods on biological properties of red, brown and green seaweeds from the central west coast of portugal
Abstract
Seaweeds are an excellent source of bioactive compounds, and therefore the use of sustainable and food compatible extraction methods such as enzyme-assisted (EAE) and ultrasound-assisted extraction were applied on Sargassum muticum, Osmundea pinnatifida, and Codium tomentosum. Extracts were evaluated for proximate characterization and biological properties. Higher extraction yields were observed for C. tomentosum EAE (48-62%; p < 0.05 for Cellulase and Viscozyme), followed by O. pinnatifida (49-55%; p < 0.05 except Alcalase) and S. muticum (26-31%; p < 0.05). S. muticum extracts presented the highest nitrogen (25 ± 2 mg/glyoph extract) and total phenolics (261 ± 37 μgcatechol equiv/glyoph extract) contents, whereas higher sugars (78 ± 14 mgglucose equiv/glyoph extract) including sulfated polysaccharide (44 ± 8 mgNa2SO4 acid/glyoph extract) contents characterized O. pinnatifida extracts. A higher effect on hydroxyl-radical scavenging activity (35-50%) was observed for all extracts, whereas S. muticum Alcalase and C. tomentosum Cellulase extracts exhibited higher prebiotic activity than fructooligosaccharides. O. pinnatifida and C. tomentosum EAE showed inhibitory potential against α-glucosidase (38-49%).
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Marine macroalgae possess a wide range of bioactivities, such as anti-aging, antioxidant, antimicrobial, antiproliferative, anti-inflammatory, antidiabetic, and neuroprotective activity.
“Due to the presence of biocompounds in macroalgae, they possess a wide range of bioactivities, such as anti-aging, antioxidant, antimicrobial, antiproliferative, anti-inflammatory, antidiabetic, and neuroprotective activity [5,6,7].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [7]
Brown algae had higher phenolic content and antioxidant activity than red and green algae.
“It was shown that brown algae had higher phenolic content and antioxidant activity than red and green algae.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [7]
Available data of UAE extraction of macroalgae shows polyphenols and antioxidants are the main extracted compounds, using solvents such as ethanol, distilled water, and methanol with different solid:solvent ratios.
“Available data of UAE extraction of macroalgae shows that polyphenols and antioxidants are the main extracted compounds from macroalgae (Table 2). Various solvents were used, such as ethanol, distilled water, and methanol with different solid:solvent ratio [7,49,50].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [7]
Seaweed extracts possess carbon sources that can be metabolized by Lactobacillus acidophilus and Bifidobacterium animalis; carbon sources are mostly polysaccharides, but not agar, because microorganisms cannot hydrolyze and metabolize it.
“Results showed that the seaweed extracts possess carbon sources that can be metabolized by mentioned bacteria. The carbon sources are mostly polysaccharides, but not agar, because microorganisms are not able to hydrolyze and metabolize it.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [7]
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- Authors
- Rodrigues, D., Sousa, S., Silva, A., Amorim, M., Pereira, L., Rocha-Santos, T. A. P., Gomes, A. M. P., Duarte, A. C., & Freitas, A. C.
- Affiliations
- Centro de Estudos do Ambiente e do Mar (PT)
- Universidade Católica Portuguesa (PT)
- MARE - Centro de Ciências do Mar e do Ambiente (PT)
- CESAM − Centre for Environmental and Marine Studies and Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal
- Corresponding author
- Rodrigues, Dina
- ORCID
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-03-18
- Volume
- 63
- Issue
- 12
- Pages
- 3177-3188
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2321001203
- Cited by
- 201
- References
- 50
- Citations by year
- 2026: 12 · 2025: 26 · 2024: 21 · 2023: 20 · 2022: 20 · 2021: 26 · 2020: 21 · 2019: 21 · 2018: 12 · 2017: 13 · 2016: 8 · 2015: 1
- FWCI
- 17.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion)
- Funders
- Ministério da Ciência, Tecnologia e Ensino Superior (SFRH/BD/77647/2011, SFRH/BPD/73781/2010)
- European Social Fund (SFRH/BD/77647/2011, SFRH/BPD/73781/2010)
- Fundação para a Ciência e a Tecnologia (PEst-C/MAR/LA0017/2013, PEst-OE/EQB/LA0016/2013, SFRH/BD/77647/2011, SFRH/BPD/73781/2010)
- Quadro de Referência Estratégico Nacional (SFRH/BD/77647/2011, SFRH/BPD/73781/2010)
- European Regional Development Fund (PEst-C/MAR/LA0017/2013, PEst-OE/EQB/LA0016/2013)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Echinoderm biology and ecology
- Keywords
- enzymatic extraction, ultrasound-assisted extraction, seaweed, Sargassum muticum, Osmundea pinnatifida, Codium tomentosum, extraction yield, phenolic content, sulfated polysaccharides, antioxidant activity, hydroxyl radical scavenging, prebiotic activity, fructooligosaccharides, α-glucosidase inhibition, bioactive compounds
- MeSH terms
- Chlorophyta, Rhodophyta, Antioxidants, Cellulase, Plant Extracts, Portugal, Seaweed, Ultrasonics, Vegetables, Sargassum, Prebiotics
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