Proapoptotic role of nuclear clusterin in brain

The BCL-2 protein family: opposing activities that mediate cell death

Youle, R. J., & Strasser, A. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2308 · Cited by 4,704 · see citing works

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326 · see citing works

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

the European Alzheimer's Disease Initiative Investigators, Lambert, J.-C., Heath, S., Even, G., Campion, D., Sleegers, K., Hiltunen, M., Combarros, O., Zelenika, D., Bullido, M. J., et al. (2009) · Nature Genetics · doi:10.1038/ng.439 · Cited by 2,234 · see citing works

BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

Cheng, E. H. Y., Wei, M. C., Weiler, S., Flavell, R. A., Mak, T. W., Lindsten, T., & Korsmeyer, S. J. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00320-3 · Cited by 1,708 · see citing works

Mechanisms of emotional arousal and lasting declarative memory.

Cahill, L., & McGaugh, J. L. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01214-9 · Cited by 1,575 · see citing works

Neuroscience: Exploring the brain

Wood, I. K. (1996) · Journal of Child and Family Studies · doi:10.1007/bf02234670 · Cited by 1,529 · see citing works

Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

Kuwana, T., Mackey, M. R., Perkins, G. A., Ellisman, M. H., Latterich, M., Schneiter, R., Green, D. R., & Newmeyer, D. D. (2002) · Cell · doi:10.1016/s0092-8674(02)01036-x · Cited by 1,480 · see citing works

The BCL-2 Family Reunion

Chipuk, J. E., Moldoveanu, T., Llambi, F., Parsons, M. J., & Green, D. R. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.01.025 · Cited by 1,432 · see citing works

BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly

Kuwana, T., Bouchier-Hayes, L., Chipuk, J. E., Bonzon, C., Sullivan, B. A., Green, D. R., & Newmeyer, D. D. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.02.003 · Cited by 1,185 · see citing works

Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak

Willis, S. N., Fletcher, J. I., Kaufmann, T., van Delft, M. F., Chen, L., Czabotar, P. E., Ierino, H., Lee, E. F., Fairlie, W. D., Bouillet, P., et al. (2007) · Science · doi:10.1126/science.1133289 · Cited by 1,125 · see citing works

Neuroscience: Exploring the Brain

Bear, M. F., Connors, B. W., & Paradiso, M. A. (1996) · Cited by 1,051 · see citing works

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

Kim, H., Rafiuddin-Shah, M., Tu, H.-C., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J.-D., & Cheng, E. H.-Y. (2006) · Nature Cell Biology · doi:10.1038/ncb1499 · Cited by 874 · see citing works

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and BakPreprint

Zong, W., Lindsten, T., Ross, A. J., MacGregor, G. R., & Thompson, C. B. (2001) · Genes & Development · doi:10.1101/gad.897601 · Cited by 809 · see citing works

Prefrontal neurons and the genetics of schizophrenia

Weinberger, D. R., Egan, M. F., Bertolino, A., Callicott, J. H., Mattay, V. S., Lipska, B. K., Berman, K. F., & Goldberg, T. E. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01252-5 · Cited by 744 · see citing works

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

Kim, H., Tu, H.-C., Ren, D., Takeuchi, O., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J.-D., & Cheng, E. H.-Y. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.09.030 · Cited by 600 · see citing works

Clusterin inhibits apoptosis by interacting with activated Bax

Zhang, H., Kim, J. K., Edwards, C. A., Xu, Z., Taichman, R., & Wang, C.-Y. (2005) · Nature Cell Biology · doi:10.1038/ncb1291 · Cited by 453 · see citing works

Connections of the retrosplenial granular a cortex in the rat

van Groen, T., & Wyss, J. M. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.903000412 · Cited by 419 · see citing works

Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid.

Blaschuk, O. W., Burdzy, K., & Fritz, I. B. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32238-5 · Cited by 401 · see citing works

Synthesis and Functional Analyses of Nuclear Clusterin, a Cell Death Protein

Leskov, K., Klokov, D. Y., Li, J., Kinsella, T. J., & Boothman, D. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209233200 · Cited by 395 · see citing works

Connections between the retrosplenial cortex and the hippocampal formation in the rat: A review

Wyss, J. M., & van Groen, T. (1992) · Hippocampus · doi:10.1002/hipo.450020102 · Cited by 379 · see citing works

Apolipoprotein J: structure and tissue distribution

De Silva, H. V., Harmony, J. A. K., Stuart, W. D., Gil, C. M., & Robbins, J. (1990) · Biochemistry · doi:10.1021/bi00474a025 · Cited by 353 · see citing works

Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer

Shannan, B., Seifert, M., Leskov, K., Willis, J. E., Boothman, D. A., Tilgen, W., & Reichrath, J. (2005) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401779 · Cited by 319 · see citing works

Connections of the retrosplenial granular b cortex in the rat

van Groen, T., & Wyss, J. M. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10757 · Cited by 302 · see citing works

A Review of the Neuroanatomical Findings in Children with Fetal Alcohol Syndrome or Prenatal Exposure to Alcohol

Roebuck, T. M., Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03658.x · Cited by 294 · see citing works

Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death

Yang, C., Leskov, K., Hosley, K., Criswell, T. L., Pink, J. J., Kinsella, T. J., & Boothman, D. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.11.5907 · Cited by 277 · see citing works

Clusterin: A forgotten player in Alzheimer's disease

Nuutinen, T., Suuronen, T., Kauppinen, A., & Salminen, A. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.05.007 · Cited by 267 · see citing works

Active cell death in hormone-dependent tissues

Tenniswood, M., Guenette, R. S., Lakins, J. N., Mooibroek, M. J., WONG, P. W. K., & Welsh, J. (1992) · Cancer and Metastasis Reviews · doi:10.1007/bf00048064 · Cited by 261 · see citing works

Neuroimaging and fetal alcohol spectrum disorders

Norman, A. L., Crocker, N., Mattson, S. N., & Riley, E. P. (2009) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.72 · Cited by 253 · see citing works

Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate

Léger, J. G., Montpetit, M. L., & Tenniswood, M. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(87)80106-7 · Cited by 250 · see citing works

Plasma clusterin and the risk of Alzheimer disease

Schrijvers, E. M. C. (2011) · JAMA · doi:10.1001/jama.2011.381 · Cited by 220 · see citing works

Modulation of different clusterin isoforms in human colon tumorigenesis

Pucci, S., Bonanno, E., Pichiorri, F., Angeloni, C., & Spagnoli, L. G. (2004) · Oncogene · doi:10.1038/sj.onc.1207404 · Cited by 216 · see citing works

Brain Diffusion Abnormalities in Children With Fetal Alcohol Spectrum Disorder

Lebel, C. A., Rasmussen, C., Wyper, K., Walker, L., Andrew, G., Yager, J. Y., & Beaulieu, C. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00750.x · Cited by 215 · see citing works

Clusterin contributes to caspase-3–independent brain injury following neonatal hypoxia-ischemia

Han, B. H., Demattos, R. B., Dugan, L. L., Kim‐Han, J. S., Brendza, R. P., Fryer, J. D., Kierson, M., Cirrito, J. R., Quick, K. L., Harmony, J. A. K., et al. (2001) · Nature Medicine · doi:10.1038/85487 · Cited by 206 · see citing works

Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1

Day, C. L., Smits, C., Fan, F. C., Lee, E. F., Fairlie, W. D., & Hinds, M. G. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.05.071 · Cited by 204 · see citing works

Intracellular Clusterin Inhibits Mitochondrial Apoptosis by Suppressing p53-Activating Stress Signals and Stabilizing the Cytosolic Ku70-Bax Protein Complex

Trougakos, I. P., Lourda, M., Antonelou, M. H., Kletsas, D., Gorgoulis, V. G., Papassideri, I. S., Zou, Y., Margaritis, L. H., Boothman, D. A., & Gonos, E. S. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-1805 · Cited by 160 · see citing works

Purification and characterization of apolipoprotein J.

Silva, H. V. D., Stuart, W. D., Park, Y. B., et al. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77299-2 · Cited by 136 · see citing works

Role of caspase-3 in ethanol-induced developmental neurodegeneration

Young, C., Roth, K. A., Klocke, B. J., West, T., Holtzman, D. M., Labruyere, J., Qin, Y.-Q., Dikranian, K. T., & Olney, J. W. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.04.014 · Cited by 117 · see citing works

Intracellular Clusterin Induces G2-M Phase Arrest and Cell Death in PC-3 Prostate Cancer Cells1

Scaltriti, M., Santamaría, A., Paciucci, R., & Bettuzzi, S. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0920 · Cited by 104 · see citing works

Advances and Challenges in Basic and Translational Research on Clusterin

Trougakos, I. P., Djeu, J. Y., Gonos, E. S., & Boothman, D. A. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2912 · Cited by 99 · see citing works

Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis

O'Sullivan, J. N., Whyte, L., Drake, J., & Tenniswood, M. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401254 · Cited by 91 · see citing works

Intracellular processing of apolipoprotein J precursor to the mature heterodimer.

Burkey, B. F., deSilva, H., & Harmony, J. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42000-0 · Cited by 91 · see citing works

Inhibition of post-ischemic brain injury by clusterin overexpression

Wehrli, P., Charnay, Y., Vallet, P. G., Zhu, G., Harmony, J. A. K., Aronow, B. J., Tschopp, J., Bouras, C., Viard, I., French, L. E., et al. (2001) · Nature Medicine · doi:10.1038/nm0901-977 · Cited by 90 · see citing works

Human gliomas and epileptic foci express high levels of a mRNA related to rat testicular sulfated glycoprotein 2, a purported marker of cell death.

Danik, M., Chabot, J., Mercier, C., Benabid, A., Chauvin, C., Quirion, R., & Suh, M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.19.8577 · Cited by 88 · see citing works

Inhibition of NF-κB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis

Takase, O., Minto, A. W., Puri, T. S., Cunningham, P. N., Jacob, A., Hayashi, M., & Quigg, R. J. (2007) · Kidney International · doi:10.1038/sj.ki.5002563 · Cited by 68 · see citing works

CSF markers of neurodegeneration in Parkinson’s disease

Vranová, H. P., Mareš, J., Nevrlý, M., Stejskal, D., Zapletalová, J., Hluštı́k, P., & Kaňovský, P. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0462-z · Cited by 67 · see citing works

Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats

Iwata, A., Browne, K., Chen, X.-H., Yuguchi, T., & Smith, D. H. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20607 · Cited by 64 · see citing works

Ethanol Induces Endoplasmic Reticulum Stress in the Developing Brain

Ke, Z., Wang, X., Liu, Y., et al. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01503.x · Cited by 62 · see citing works

Clusterin Isoforms Differentially Affect Growth and Motility of Prostate Cells: Possible Implications in Prostate Tumorigenesis

Moretti, R. M., Marelli, M. M., Mai, S., Cariboni, A. M., Scaltriti, M., Bettuzzi, S., & Limonta, P. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0516 · Cited by 61 · see citing works

Human nuclear clusterin mediates apoptosis by interacting with Bcl‐XL through C‐terminal coiled coil domain

Kim, N., Yoo, J. C., Han, J. Y., Hwang, E. M., Kim, Y. S., Jeong, E. Y., Sun, C., Yi, G., Roh, G. S., Kim, H. J., et al. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22836 · Cited by 60 · see citing works

Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread

Bettuzzi, S., Davalli, P., Davoli, S., Chayka, O., Rizzi, F., Belloni, L., Pellacani, D., Fregni, G., Astancolle, S., Fassan, M., et al. (2009) · Oncogene · doi:10.1038/onc.2009.286 · Cited by 46 · see citing works

Identification of Clusterin Domain Involved in NF-κB Pathway Regulation

Essabbani, A., Margottin-Goguet, F., & Chiocchia, G. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.c109.057133 · Cited by 42 · see citing works

Clusterin expression during fetal and postnatal CNS development in mouse

Charnay, Y., Imhof, A., Vallet, P. G., Hakkoum, D., Lathuilière, A., Poku, N., Aronow, B. J., Kovari, E., Bouras, C., & Giannakopoulos, P. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.022 · Cited by 33 · see citing works

Microglial Signal Transduction as a Target of Alcohol Action in the Brain

Suk, K. (2007) · Current Neurovascular Research · doi:10.2174/156720207780637261 · Cited by 31 · see citing works

Ketogenic diet prevents clusterin accumulation induced by kainic acid in the hippocampus of male ICR mice

Noh, H. S., Kim, D. W., Kang, S. S., et al. (2005) · Brain Research · doi:10.1016/j.brainres.2005.01.097 · Cited by 30 · see citing works

Seizure activity causes a rapid increase in sulfated glycoprotein-2 messenger RNA in the adult but not the neonatal rat brain

Schreiber, S. S., Tocco, G., Najm, I., & Baudry, M. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90066-t · Cited by 29 · see citing works

Interaction of a putative BH3 domain of clusterin with anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy

Lee, D., Ha, J., Kim, Y., Bae, K., Park, J., Choi, W. S., Yoon, H. S., Park, S. G., Park, B. C., Yi, G.-S., et al. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.04.054 · Cited by 24 · see citing works

Nuclear Clusterin Is Associated with Neuronal Apoptosis in the Developing Rat Brain upon Ethanol Exposure

Kim, N., Han, J. Y., Roh, G. S., et al. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01588.x · Cited by 18 · see citing works

Clusterin increases post‐ischemic damages in organotypic hippocampal slice cultures

Hakkoum, D., Imhof, A., Vallet, P. G., Boze, H., Moulin, G., Charnay, Y., Stoppini, L., Aronow, B. J., Bouras, C., & Giannakopoulos, P. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05519.x · Cited by 17 · see citing works

A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin

Deming, Y., Xia, J., Cai, Y., Lord, J., Holmans, P., Bertelsen, S., Holtzman, D., Morris, J. C., Bales, K., Pickering, E. H., et al. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.09.009 · Cited by 66 · see citing works

DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION

Mustafa, N. H., Kelesbayev, D., & Alibekova, Z. D. (2018) · The Journal of Economic Research & Business Administration · doi:10.26577/be-2018-2-2141

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Genentech taps Affimed’s antibodies

Cross, R. (2018) · C&EN Global Enterprise · doi:10.1021/cen-09635-buscon15

Detection of Clusterin in Saliva on the Various Systemic Condition

김학찬, 전이선, 전양현, et al. (2004) · Journal of oral medicine

Cerebrospinal fluid and plasma clusterin levels in Parkinson's disease

van Dijk, K. D., Jongbloed, W., Heijst, J. A., Teunissen, C. E., Groenewegen, H. J., Berendse, H. W., van de Berg, W. D. J., & Veerhuis, R. (2013) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.07.016 · Cited by 37 · see citing works