Ischemic stroke and shift work
Open accessAbstract
OBJECTIVES: This study analyzed the potential association between shift work and ischemic stroke. METHODS: The analysis was carried out using a nested case-control study consisting of 138 shift workers and 469 day workers from the register of the Northern Sweden Monitoring of Trends and Determinants in Cardiovascular Diseases (MONICA) study and the Västerbotten Intervention Programme. Logistic regression analysis was used to analyze the risk estimate for day workers in a comparison with shift workers and the risk of ischemic stroke. RESULTS: The crude odds ratio for shift workers' risk of experiencing an ischemic stroke was 1.0 (95% confidence interval 0.6-1.8) for both the men and the women. The risk estimates were consistent despite the introduction of several recognized risk factors for ischemic stroke in the logistic regression models. CONCLUSIONS: In the present study, none of the findings indicated a higher risk of shift workers undergoing an ischemic stroke than day workers.
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Working night and rotating shifts is associated with elevated risk of heart disease and ischemic stroke.
“Working night shifts and rotating shifts has been associated with elevated risk of heart disease [76] and ischemic stroke [77,78].”
From Shift Work: Disrupted Circadian Rhythms and Sleep—Implications for Health and Well-being (2017) · cites this paper as [77]
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Cites
Job Demands, Job Decision Latitude, and Mental Strain: Implications for Job Redesign
Karasek, R. A. (1979) · Administrative Science Quarterly · doi:10.2307/2392498 · Cited by 12,597 · see citing works
WHO MONICA Project Principal Invest (1988) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(88)90084-4 · Cited by 1,798 · see citing works
Health disorders of shift workers
Knutsson, A. (2003) · Occupational Medicine · doi:10.1093/occmed/kqg048 · Cited by 1,218 · see citing works
Self-citationChanges in job strain in relation to changes in physiological state. A longitudinal study.
Theorell, T., Perski, A., Åkerstedt, T., Sigala, F., Ahlberg-Hultén, G., Svensson, J., & Eneroth, P. H. E. (1988) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.1932 · Cited by 468 · see citing works
American Heart Association Prevention Conference IV: Prevention and Rehabilitation of Stroke
Helgason, C. M., & Wolf, P. A. (1997) · Stroke · doi:10.1161/01.str.28.7.1498 · Cited by 440 · see citing works
Diagnostic Criteria and Quality Control of the Registration of Stroke Events in the MONICA Project
Asplund, K., Tuomilehto, J., Stegmayr, B. G., Wester, P. O., & Tunstall‐Pedoe, H. (1988) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1988.tb05550.x · Cited by 197 · see citing works
Self-citationWeinehall, L. (1998) · Scandinavian Journal of Primary Health Care · doi:10.1080/028134398750003133 · Cited by 191 · see citing works
Karlsson, B., Alfredsson, L. S., Knutsson, A., Andersson, E., & Torén, K. (2005) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.845 · Cited by 149 · see citing works
Self-citationTrends in incidence, case-fatality rate, and severity of stroke in northern Sweden, 1985-1991.
Stegmayr, B. G., Asplund, K., & Wester, P. O. (1994) · Stroke · doi:10.1161/01.str.25.9.1738 · Cited by 117 · see citing works
Self-citationVirtanen, S. V., & Notkola, V. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.3.614 · Cited by 100 · see citing works
Weinehall, L., Johnson, Jansson, Boman, Huhtasaari, Hallmans, Dahlén, & Wall (1998) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1998.00201.x · Cited by 67 · see citing works
Weinehall, L., Westman, G. A., Hellsten, G., Boman, K., Hallmans, G., Pearson, T. A., & Wall, S. (1999) · Journal of Epidemiology & Community Health · doi:10.1136/jech.53.4.243 · Cited by 65 · see citing works
Stegmayr, B., & Asplund, K. (2003) · Scandinavian Journal of Public Health · doi:10.1080/14034950310001379 · Cited by 39 · see citing works
Self-citationStroke morbidity in professional drivers in Denmark 1981-1990
Tüchsen, F. (1997) · International Journal of Epidemiology · doi:10.1093/ije/26.5.989 · Cited by 22 · see citing works
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Research works printed but not linked: 2
- Bøggild H, Knutsson A. Shift work, risk factors and cardio- vascular disease [review]. Scand J Work Environ Health. 1999;25(2):85-99.
- von Schenk H, Treichl L, Tilling B, Olsson A. Laboratory and field evaluation of three desk top instruments for blood choles- terol and triglyceride assay. Clin Chem. 1987;33:1230-2.
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Shift work and vascular events: systematic review and meta-analysis
Vyas, M. V., Garg, A. X., Iansavichus, A. V., Costella, J., Donner, A., Laugsand, L. E., Janszky, I., Mrkobrada, M., Parraga, G., & Hackam, D. G. (2012) · BMJ · doi:10.1136/bmj.e4800 · Cited by 840 · see citing works
Shift work and chronic disease: the epidemiological evidence
Wang, X.-S., Armstrong, M. E. G., Cairns, B. J., Key, T. J., & Travis, R. C. (2011) · Occupational Medicine · doi:10.1093/occmed/kqr001 · Cited by 640 · see citing works
Shift Work: Disrupted Circadian Rhythms and Sleep—Implications for Health and Well-being
James, S. M., Honn, K. A., Gaddameedhi, S., & Van Dongen, H. P. A. (2017) · Current Sleep Medicine Reports · doi:10.1007/s40675-017-0071-6 · Cited by 517 · see citing works
Torquati, L., Mielke, G. I., Brown, W. J., & Kolbe-Alexander, T. (2018) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.3700 · Cited by 510 · see citing works
Rotating Night Shift Work and the Risk of Ischemic Stroke
Brown, D. L., Feskanich, D., Sanchez, B. N., Rexrode, K. M., Schernhammer, E. S., & Lisabeth, L. D. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp056 · Cited by 297 · see citing works
The effects of shift work on physical and mental health
Vogel, M., Braungardt, T., Meyer, W. T., & Schneider, W. (2012) · Journal of Neural Transmission · doi:10.1007/s00702-012-0800-4 · Cited by 198 · see citing works
The REV-ERBs and RORs: Molecular Links Between Circadian Rhythms and Lipid Homeostasis
Solt, L. A., Kojetin, D. J., & Burris, T. P. (2011) · Future Medicinal Chemistry · doi:10.4155/fmc.11.9 · Cited by 177 · see citing works
Dietary and lifestyle habits and the associated health risks in shift workers
Nea, F. M., Kearney, J. M., Livingstone, M. B. E., Pourshahidi, L. K., & Corish, C. A. (2015) · Nutrition Research Reviews · doi:10.1017/s095442241500013x · Cited by 144 · see citing works
Wallace, D. M., Ramos, A. R., & Rundek, T. (2012) · International Journal of Stroke · doi:10.1111/j.1747-4949.2011.00760.x · Cited by 135 · see citing works
Night Shift Work and Hormone Levels in Women
Davis, S., Mirick, D. K., Chen, C., & Stanczyk, F. Z. (2012) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-11-1128 · Cited by 132 · see citing works
Sleep disorders and the risk of stroke
McDermott, M., Brown, D. L., & Chervin, R. D. (2018) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2018.1489239 · Cited by 121 · see citing works
Daytime Sleepiness and Risk of Stroke and Vascular Disease
Boden-Albala, B. M., Roberts, E. T., Bazil, C. W., Moon, Y. P., Elkind, M. S. V., Rundek, T., Paik, M. C., & Sacco, R. L. (2012) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.111.963801 · Cited by 116 · see citing works
Dutheil, F., Baker, J. S., Mermillod, M., Cesare, M. D., Vidal, A., Moustafa, F., Pereira, B., & Navel, V. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.08.015 · Cited by 102 · see citing works
Night Shift Work and Levels of 6-Sulfatoxymelatonin and Cortisol in Men
Mirick, D. K., Bhatti, P., Chen, C., Nordt, F. J., Stanczyk, F. Z., & Davis, S. (2013) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-12-1377 · Cited by 95 · see citing works
Duss, S. B., Brill, A., Bargiotas, P., Facchin, L., Alexiev, F., Manconi, M., & Bassetti, C. L. (2018) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-018-0879-6 · Cited by 74 · see citing works
Burgueño, A., Gemma, C., Gianotti, T. F., Sookoian, S., & Pirola, C. J. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.12.032 · Cited by 53 · see citing works
Bigert, C., Kader, M., Andersson, T., Selander, J., Bodin, T., Gustavsson, P., Härmä, M., Ljungman, P. L. S., & Albin, M. C. (2021) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.3986 · Cited by 45 · see citing works
Night Work and the Reproductive Health of Women: An Integrated Literature Review
Chau, Y. M., West, S. H., & Mapedzahama, V. (2013) · Journal of Midwifery & Women s Health · doi:10.1111/jmwh.12052 · Cited by 40 · see citing works
Circadian control of β ‐cell function and stress responses
Lee, J., Liu, R., de Jesus, D. S., Kim, B. S., Ma, K., Moulik, M., & Yechoor, V. K. (2015) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12524 · Cited by 42 · see citing works
Shift work and risk of stroke: A meta-analysis
Li, M., Huang, J., Tan, Y., Yang, B., & Tang, Z. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.03.052 · Cited by 35 · see citing works
Cullen, P., Cahill, J., & Gaynor, K. (2021) · Aviation Psychology and Applied Human Factors · doi:10.1027/2192-0923/a000199 · Cited by 35 · see citing works
Sookoian, S. C., Gianotti, T. F., Burgueño, A. L., & Pirola, C. J. (2010) · Chronobiology International · doi:10.3109/07420528.2010.496913 · Cited by 30 · see citing works
Li, X., He, Y., Wang, D., & Momeni, M. R. (2024) · Clinical and Experimental Medicine · doi:10.1007/s10238-024-01514-w · Cited by 27 · see citing works
Work-related Cerebro-Cardiovascular Diseases in Korea
Kim, D.-S., & Kang, S. (2010) · Journal of Korean Medical Science · doi:10.3346/jkms.2010.25.s.s105 · Cited by 21 · see citing works
Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine
Sookoian, S., & Pirola, C. J. (2013) · Current Diabetes Reports · doi:10.1007/s11892-012-0361-9 · Cited by 19 · see citing works
The human circadian clock from health to economics
Koritala, B. S. C., & Çakmaklı, S. (2018) · PsyCh Journal · doi:10.1002/pchj.252 · Cited by 16 · see citing works
Shift Work and Early Arterial Stiffness: A Systematic Review
Gusmão, W. D. P., Pureza, I. R. D. O. M., & Moreno, C. R. D. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192114569 · Cited by 17 · see citing works
Assisting shift workers through sleep and circadian research
Takahashi, M. (2014) · Sleep and Biological Rhythms · doi:10.1111/sbr.12065 · Cited by 17 · see citing works
Rissardo, J. P., Khalil, I., Taha, M. R., Chen, J., Sayad, R., & Caprara, A. L. F. (2025) · Medical Sciences · doi:10.3390/medsci13030113 · Cited by 17 · see citing works
Healthy Diet and Reduction of Chronic Disease Risks of Night Shift Workers
Ferri, G. M., Cavone, D., Intranuovo, G., & Macinagrossa, L. (2017) · Current Medicinal Chemistry · doi:10.2174/0929867324666170720160632 · Cited by 15 · see citing works
Fesharaki, M. G., Kazemnejad, A., Zayeri, F., Sanati, J., & Akbari, H. (2013) · Iranian Red Crescent Medical Journal · doi:10.5812/ircmj.10930 · Cited by 13 · see citing works
The interplay between retinoic acid receptor-related orphan receptors and human diseases
Ranhotra, H. S. (2012) · Journal of Receptors and Signal Transduction · doi:10.3109/10799893.2012.692120 · Cited by 12 · see citing works
Arbetstider, hälsa och säkerhet - en uppdatering av aktuell forskning
Kecklund, G., Ingre, M., & Åkerstedt, T. (2010) · Cited by 8 · see citing works
Maternal shift work during pregnancy and cardiovascular health impacts on mother and offspring
Flores, R. C., Yaffe, R., Nhunzwi, M. M., Nguyen, H., & Rabinovich-Nikitin, I. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2024.12.008 · Cited by 7 · see citing works
Dong, X., Liu, H., Huang, Z., Liu, K., Zhang, R., Sun, S., Feng, B., Guo, H., & Feng, S. (2024) · BMC Public Health · doi:10.1186/s12889-024-20885-z · Cited by 6 · see citing works
Shift work and cardiovascular events: systematic review and meta-analysis
Vyas, M. V. (2012) · Scholarship@Western (Western University) · Cited by 1 · see citing works
The Impact of Shift Work and Circadian Dysregulation on Women’s Health
Choi, J. H., & Abbott, S. M. (2020) · Current clinical neurology · doi:10.1007/978-3-030-40842-8_12 · Cited by 1 · see citing works
Circadian Control of Islet Function
Lee, J., Moulik, M., & Yechoor, V. K. (2014) · Springer eBooks · doi:10.1007/978-94-007-6686-0_43
Melatonino fiziologinė reikšmė organizmui
Černyšiov, V., Mauricas, M., & Girkontaitė, I. (2014) · Sveikatos mokslai · doi:10.5200/sm-hs.2014.035
Shift Work and Neurological Disease
Jh, L. (2017) · Journal of Headache & Pain Management · doi:10.4172/2472-1913.100034
Health Consequences of Circadian Disruption
Rogers, N. L., & Whitwell, B. G. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-378610-4.00274-6
Shift work and cardiovascular events : a reanalysis of a systematic review
Nwankwo, C. P. (2014) · UEF eRepo (University of Eastern Finland)
Circadian Control of Islet Function
Lee, J., Moulik, M., & Yechoor, V. K. (2013) · Springer eBooks · doi:10.1007/978-94-007-6884-0_43-1
Kresna, A., Fuk, L. J., Widyahening, I. S., Soemarko, D. S., & Fitriani, D. Y. (2023) · Occupational and Environmental Medicine Journal of Indonesia · doi:10.7454/oemji.v1i2.1022
Wang, L., Huang, Y., Chen, T., & Liu, T. (2026) · Aerosol and Air Quality Research · doi:10.1007/s44408-026-00124-3
Huang, Y., Tan, M.-H., Wang, G., Liang, S., Lyu, J., & Huang, L. (2026) · Journal of Neurology · doi:10.1007/s00415-026-13827-9
- Authors
- Hermansson, J., Gillander Gådin, K., Karlsson, B., Lindahl, B., Stegmayr, B., & Knutsson, A.
- Affiliations
- Mid Sweden University (SE)
- Umeå University (SE)
- Venue
- Scandinavian Journal of Work, Environment & Health
- Published
- 2007-12
- Volume
- 33
- Issue
- 6
- Pages
- 435-439
- ISSN
- 0355-3140 (ISSN-L)
- 1795-990X
- OpenAlex
- W1971134435
- Cited by
- 46
- References
- 14
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2018: 3 · 2017: 4 · 2016: 1 · 2015: 2 · 2014: 4 · 2013: 6 · 2012: 7
- FWCI
- 2.14
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Scandinavian Journal of Work Environment & Health (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Health Sciences › Health Professions › General Health Professions › Workplace Health and Well-being
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Keywords
- ischemic stroke, shift work, day laborers, occupational health, cardiovascular risk factors, stroke risk
- MeSH terms
- Adult, Aged, Brain Ischemia, Female, Humans, Male, Middle Aged, Risk Factors, Sweden, Work Schedule Tolerance, Odds Ratio, Case-Control Studies, Stroke
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