Increased levels of resistin in rotating shift workers: A potential mediator of cardiovascular risk associated with circadian misalignment
Abstract
Objective Shift work schedule has been associated with several health problems, including deleterious effects on the cardiovascular system. The present study aimed to evaluate the circulating levels of four biomarkers of atherosclerosis (soluble CD40 ligand [sCD40L], monocyte chemoattractant protein-1 [MCP-1], resistin, and plasminogen activator inhibitor-1 [PAI-1]) in a population-based sample of young adult men exposed to rotating shift work schedule in comparison with day workers. Design and participants A total of 439 men aged 34.4+/-8.6 years were included in a cross-sectional study comparing 255 day workers with 184 rotating shift workers. Circulating levels of the biomarkers were measured in duplicate by ELISA using monoclonal specific antibodies. Results Rotating shift workers had elevated (6440+/-4510 pg/mL) (mean+/-SD) circulating levels of resistin in comparison with day workers (5450+/-3780 pg/mL), and significance remains after adjusting for age and blood leukocyte count (p<0.045, ANCOVA). Shift work schedule explains 1% of the proportion of the total variation in the circulating resistin levels. Multiple regression analysis showed that resistin levels significantly correlate with rotating shift work (p<0.04) and blood leukocyte count (p<0.00003) independently of age, BMI, waist-hip ratio, HOMA, and cardiovascular risk %. Circulating levels of sCD40L, MCP-1, and PAI-1 did not significantly differ between day workers and shift workers. Conclusion Shift work schedule was significantly associated with elevated plasma resistin levels. Resistin, which is probably produced by leukocytes, may play an important role in the pathogenesis of early metabolic syndrome components in young men chronically exposed to circadian misalignment.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Shift work-related metabolic dysfunction and its consequences, including obesity, metabolic syndrome, and type II diabetes, potentiate cardiovascular disease development.
“Shift work-related metabolic dysfunction and the various health consequences thereof, including obesity, metabolic syndrome, and type II diabetes (discussed above), also potentiate the development of CVD [88,89].”
From Shift Work: Disrupted Circadian Rhythms and Sleep—Implications for Health and Well-being (2017) · cites this paper as [89]
Cites
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Atherosclerosis--an inflammatory disease
Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725 · see citing works
Adverse metabolic and cardiovascular consequences of circadian misalignment
Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808180106 · Cited by 2,351 · see citing works
Karlsson, B., Knutsson, A., & Lindahl, B. (2001) · Occupational and Environmental Medicine · doi:10.1136/oem.58.11.747 · Cited by 924 · see citing works
Resistin is expressed in human macrophages and directly regulated by PPARγ activators
Patel, L., Buckels, A. C., Kinghorn, I. J., Murdock, P. R., Holbrook, J. D., Plumpton, C., Macphee, C. H., & Smith, S. A. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02841-3 · Cited by 920 · see citing works
Resistin Is an Inflammatory Marker of Atherosclerosis in Humans
Reilly, M. P., Lehrke, M., Wolfe, M. L., Rohatgi, A. K., Lazar, M. A., & Rader, D. J. (2005) · Circulation · doi:10.1161/01.cir.0000155620.10387.43 · Cited by 909 · see citing works
Ylä‐Herttuala, S., Lipton, B. A., Rosenfeld, M. E., Särkioja, T., Yoshimura, T., Leonard, E. J., Witztum, J. L., & Steinberg, D. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.12.5252 · Cited by 871 · see citing works
Tobin, M. D., Sheehan, N. A., Scurrah, K. J., & Burton, P. R. (2005) · Statistics in Medicine · doi:10.1002/sim.2165 · Cited by 695 · see citing works
Resistin Promotes Endothelial Cell Activation
Verma, S., Li, S., Wang, C., Fedak, P. W. M., Li, R., Weisel, R. D., & Mickle, D. A. G. (2003) · Circulation · doi:10.1161/01.cir.0000084503.91330.49 · Cited by 670 · see citing works
A Prospective Analysis of the HOMA Model: The Mexico City Diabetes Study
Haffner, S. M., González, C. R., Miettinen, H., Kennedy, E., & D, M. P. S. M. (1996) · Diabetes Care · doi:10.2337/diacare.19.10.1138 · Cited by 553 · see citing works
Increased risk of ischaemic heart disease in shift workers
Knutsson, A., Jonsson, B., Akerstedt, T., & Orth-Gomer, K. (1986) · The Lancet · doi:10.1016/s0140-6736(86)91619-3 · Cited by 459 · see citing works
Sleep and the epidemic of obesity in children and adults
Van Cauter, E., & Knutson, K. L. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0298 · Cited by 427 · see citing works
Biological Clocks and Shift Work: Circadian Dysregulation and Potential Long-term Effects
Haus, E. L., & Smolensky, M. H. (2006) · Cancer Causes & Control · doi:10.1007/s10552-005-9015-4 · Cited by 391 · see citing works
Metabolic disturbances in male workers with rotating three-shift work. Results of the WOLF study
Karlsson, B. H., Knutsson, A., Lindahl, B., & Alfredsson, L. S. (2003) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-003-0440-y · Cited by 316 · see citing works
Effects of rotating shift work on biomarkers of metabolic syndrome and inflammation
Sookoian, S. C., Gemma, C., Gianotti, T. F., Burgueño, A. L., Alvarez, A., González, C. D., & Pirola, C. J. (2007) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2007.01766.x · Cited by 315 · see citing works
Self-citationLight Treatment for Sleep Disorders: Consensus Report
Eastman, C. I., Boulos, Z., Terman, M., Campbell, S. S., Dijk, D., & Lewy, A. J. (1995) · Journal of Biological Rhythms · doi:10.1177/074873049501000208 · Cited by 272 · see citing works
The potential role of resistin in atherogenesis
Burnett, M. S., Lee, C. W., Kinnaird, T. D., Stabile, E., Durrani, S., Dullum, M. K. C., Devaney, J. M., Fishman, C., Stamou, S. C., Caños, D., et al. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.02.014 · Cited by 249 · see citing works
A Prospective Cohort Study of Shift Work and Risk of Ischemic Heart Disease in Japanese Male Workers
Fujino, Y., Iso, H., Tamakoshi, A., Inaba, Y., Koizumi, A., Kubo, T., & Yoshimura, T. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj185 · Cited by 225 · see citing works
OOLOFESSON, B. O., Dahlén, G., & Nilsson, T. (1989) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a059384 · Cited by 225 · see citing works
Shiftwork and myocardial infarction: a case-control study.
Knutsson, A., Hallquist, J., Reuterwall, C., Theorell, T., & Åkerstedt, T. (1999) · Occupational and Environmental Medicine · doi:10.1136/oem.56.1.46 · Cited by 208 · see citing works
Reilly, M. P., Wolfe, M. L., Rhodes, T., Girman, C., Mehta, N., & Rader, D. J. (2004) · Circulation · doi:10.1161/01.cir.0000138740.84883.9c · Cited by 185 · see citing works
(1824) · The Lancet · doi:10.1016/s0140-6736(02)92910-7 · Cited by 161 · see citing works
Haupt, C. M., Alte, D., Dörr, M., Robinson, D. M., Felix, S. B., John, U., & Völzke, H. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.12.059 · Cited by 144 · see citing works
Twenty-four-hour ambulatory blood pressure in shift workers.
Chau, N. P., Mallion, J. M., Gaudemaris, R. D., Ruche, E., Siche, J. P., Pelen, O., & Mathern, G. W. (1989) · Circulation · doi:10.1161/01.cir.80.2.341 · Cited by 140 · see citing works
Kunnari, A., Ukkola, O. H., Päivänsalo, M. J., & Kesäniemi, Y. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2115 · Cited by 138 · see citing works
Puttonen, S., Mika Kivimaki, B., Elovainio, M. J., Pulkki-Råbäck, L., Hintsanen, M., Vahtera, J., Telama, R., Juonala, M., Viikari, J. S. A., Raitakari, O. T., et al. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.01.016 · Cited by 118 · see citing works
Resistin, acute coronary syndrome and prognosis results from the AtheroGene study
Lubos, E., Messow, C., Schnabel, R. B., Rupprecht, H. J., Espinola–Klein, C., Bickel, C., Peetz, D., Post, F., Lackner, K. J., Tiret, L., et al. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.05.039 · Cited by 109 · see citing works
Hasenstab, D., Lea, H. J., & Clowes, A. W. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.3.853 · Cited by 56 · see citing works
Santos, R. D., & Nasir, K. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.12.017 · Cited by 51 · see citing works
Ischemic stroke and shift work
Hermansson, J., Gillander Gådin, K., Karlsson, B., Lindahl, B., Stegmayr, B., & Knutsson, A. (2007) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.1165 · Cited by 46 · see citing works
Resistin as a putative modulator of insulin action in the daily feeding/fasting rhythm
Oliver, P., Ribot, J., Rodríguez, A. M., Sánchez, J., Picó, C., & Palou, A. (2006) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-005-0034-5 · Cited by 44 · see citing works
Smith, L. R., Macdonald, I., Folkard, S., & Tucker, P. (1998) · Applied Ergonomics · doi:10.1016/s0003-6870(97)00059-8 · Cited by 38 · see citing works
Shyu, K. G., Chua, S., Wang, B.-W., & Kuan, P. (2009) · Journal of Biomedical Science · doi:10.1186/1423-0127-16-50 · Cited by 27 · see citing works
Flagged first, then by citations
1 of the 35 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Circadian misalignment increases cardiovascular disease risk factors in humans
Morris, C. J., Purvis, T. E., Hu, K., & Scheer, F. A. J. L. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516953113 · Cited by 691 · see citing works
Shift Work: Disrupted Circadian Rhythms and Sleep—Implications for Health and Well-being
James, S. M., Honn, K. A., Gaddameedhi, S., & Van Dongen, H. P. A. (2017) · Current Sleep Medicine Reports · doi:10.1007/s40675-017-0071-6 · Cited by 517 · see citing works
Hardeland, R., Madrid, J. A., Tan, D. X., & Reiter, R. J. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00934.x · Cited by 449 · see citing works
The Impact of Sleep and Circadian Disturbance on Hormones and Metabolism
Kim, T., Jeong, J., & Hong, S. (2015) · International Journal of Endocrinology · doi:10.1155/2015/591729 · Cited by 378 · see citing works
Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure
Bonmatí‐Carrión, M., Argüelles-Prieto, R., Martínez-Madrid, M. J., Reiter, R. J., Hardeland, R., Rol, M. A., & Madrid, J. A. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms151223448 · Cited by 238 · see citing works
Circadian regulation of metabolism
Bailey, S. M., Udoh, U. S., & Young, M. E. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0200 · Cited by 211 · see citing works
Kervezee, L., Kosmadopoulos, A., & Boivin, D. B. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14216 · Cited by 216 · see citing works
Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers
Morris, C. J., Purvis, T. E., Mistretta, J., Hu, K., & Scheer, F. A. J. L. (2017) · Journal of Biological Rhythms · doi:10.1177/0748730417697537 · Cited by 209 · see citing works
Shift work and cardiovascular risk factors: New knowledge from the past decade
Esquirol, Y., Perret, B., Ruidavets, J. B., Marquié, J. C., Diène, E., Niezborala, M., & Ferrières, J. (2011) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2011.09.004 · Cited by 173 · see citing works
The impact of shiftwork on health: a literature review
Matheson, A., O’Brien, L., & Reid, J. (2014) · Journal of Clinical Nursing · doi:10.1111/jocn.12524 · Cited by 142 · see citing works
Shift work and metabolic syndrome, diabetes mellitus and ischaemic heart disease
Szosland, D. (2010) · International Journal of Occupational Medicine and Environmental Health · doi:10.2478/v10001-010-0032-5 · Cited by 121 · see citing works
Neuroendocrine, immune and oxidative stress in shift workers
Faraut, B., Bayon, V., & Léger, D. (2013) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2012.12.006 · Cited by 112 · see citing works
Dutheil, F., Baker, J. S., Mermillod, M., Cesare, M. D., Vidal, A., Moustafa, F., Pereira, B., & Navel, V. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.08.015 · Cited by 102 · see citing works
Daily regulation of hormone profiles.
Kalsbeek, A., & Fliers, E. (2013) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-25950-0_8 · Cited by 91 · see citing works
Leu, H., Chung, C., Lin, S., Chiang, K.-M., Yang, H., Ho, H., Ting, C.-T., Lin, T., Sheu, S., Tsai, W., et al. (2014) · Hypertension Research · doi:10.1038/hr.2014.152 · Cited by 50 · see citing works
Assessment of cardiometabolic risk among shift workers in Hungary
Jermendy, G., Nádas, J., Hegyi, I., Vasas, I., & Hídvégi, T. (2012) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-10-18 · Cited by 46 · see citing works
McCarthy, M. J. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100412 · Cited by 37 · see citing works
Circadian Dysfunction in Adipose Tissue: Chronotherapy in Metabolic Diseases
Civelek, E., Civelek, D. Ö., Akyel, Y. K., Durman, D. K., & Okyar, A. (2023) · Biology · doi:10.3390/biology12081077 · Cited by 34 · see citing works
Sookoian, S. C., Gianotti, T. F., Burgueño, A. L., & Pirola, C. J. (2010) · Chronobiology International · doi:10.3109/07420528.2010.496913 · Cited by 30 · see citing works
Self-citationNutrigenetics and Nutrimiromics of the Circadian System: The Time for Human Health
Micó, V., Díez-Ricote, L., & Daimiel, L. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17030299 · Cited by 30 · see citing works
Rest-activity rhythms in emerging adults: implications for cardiometabolic health
Hoopes, E. K., Witman, M. A., D’Agata, M. N., Berube, F. R., Brewer, B. C., Malone, S. K., Grandner, M. A., & Patterson, F. (2021) · Chronobiology International · doi:10.1080/07420528.2020.1868490 · Cited by 29 · see citing works
Night shift work and indicators of cardiovascular risk: A systematic review and meta-analysis
Erdem, J. S., Das, M. K., Ryck, E. D., Skare, Ø., Lie, J.-A. S., Bugge, M., Harding, B. N., Jørgensen, I. L., Mehlum, I. S., Kogevinas, M., et al. (2025) · Environmental Research · doi:10.1016/j.envres.2025.121503 · Cited by 30 · see citing works
Circadian rhythm disruption: health consequences
Sharma, A., Tiwari, S., & Singaravel, M. (2015) · Biological Rhythm Research · doi:10.1080/09291016.2015.1103942 · Cited by 28 · see citing works
Circadian rhythms in white adipose tissue
van der Spek, R., Kreier, F., Fliers, E., & Kalsbeek, A. (2012) · Progress in brain research · doi:10.1016/b978-0-444-59427-3.00011-3 · Cited by 28 · see citing works
The Adverse Health Effects of Shift Work in Relation to Risk of Illness/Disease: A Review
Shariat, A., Bahri Mohd Tamrin, S., Daneshjoo, A., & Sadeghi, H. (2015) · Acta Medica Bulgarica · doi:10.1515/amb-2015-0009 · Cited by 26 · see citing works
Nutra-ergonomics: influence of nutrition on physical employment standards and the health of workers
Shearer, J., Graham, T. E., & Skinner, T. L. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0531 · Cited by 24 · see citing works
Shift-work: a review of the health consequences
Silva, A., Silva, A. M. N., Duarte, J., & Costa, J. T. (2020) · International Journal of Occupational and Environmental Safety · doi:10.24840/2184-0954_004.002_0005 · Cited by 26 · see citing works
The human circadian clock from health to economics
Koritala, B. S. C., & Çakmaklı, S. (2018) · PsyCh Journal · doi:10.1002/pchj.252 · Cited by 16 · see citing works
The Role of Work Schedules in Occupational Health and Safety
Geiger-Brown, J. M., Lee, C. J., & Trinkoff, A. M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4839-6_14 · Cited by 15 · see citing works
Łagowska, K., Kuleta, A., Michalak, M., & Bajerska, J. (2024) · American Journal of Human Biology · doi:10.1002/ajhb.24041 · Cited by 15 · see citing works
Shift Work, Genetic Factors, and the Risk of Heart Failure
Xu, C. Y., Weng, Z., Liang, J., Liu, Q., Zhang, X., Xu, J., Li, Q., Zhou, Y., & Gu, A. (2022) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2021.12.003 · Cited by 12 · see citing works
Early Effect of Bariatric Surgery on the Circadian Rhythms of Adipokines in Morbidly Obese Women
Justus, J. F. C., Campos, A. C. L., Figueroa, A. L. C., Gomis, R., Santo, M. A., Fávero, G. M., Milléo, F. Q., & Vieira, E. C. (2015) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2015.0051 · Cited by 12 · see citing works
Gerami, H., Javadi, M., Hosseini, S. K., Maljaei, M., & Fakhrzadeh, H. (2018) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-018-0362-6 · Cited by 9 · see citing works
Brøns, C., Saltbæk, P. N., Friedrichsen, M. H., Chen, Y., & Vaag, A. A. (2016) · European Journal of Endocrinology · doi:10.1530/eje-16-0177 · Cited by 9 · see citing works
The erythrocyte membrane stability is associated with sleep time and social jetlag in shift workers
Teixeira, K. R., de Medeiros, L. A., Mendes, J. A., Vaz, E. R., Cunha, T. M., de Oliveira, E. P., Penha‐Silva, N., & Crispim, C. A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222698 · Cited by 8 · see citing works
Pan, A., Devore, E. E., & Schernhammer, E. S. (2015) · Wiley eBooks · doi:10.1002/9781118467831.ch13 · Cited by 6 · see citing works
Sooriyaarachchi, P., Jayawardena, R., Pavey, T., & King, N. A. (2023) · Indian Journal of Occupational and Environmental Medicine · doi:10.4103/ijoem.ijoem_326_22 · Cited by 5 · see citing works
Health Effects of Shift Work and Night Shift Work
Guénel, P., & Léger, D. (2023) · Handbook series in occupational health sciences · doi:10.1007/978-3-031-30492-7_19 · Cited by 4 · see citing works
Shafer, B. M., McAuliffe, K., Kogan, S. A., Davis, M. C., Shea, S. A., Olson, R., & McHill, A. W. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00735.2025 · Cited by 3 · see citing works
The Impact of Shift Work-Related Circadian Rhythm Disruption on Inflammatory Biomarkers
Suyagh, M. F., Alefishat, E. A., Farha, R. K. A., Akour, A. A., Kasabri, V. N., & Bulatova, N. (2018) · Jordan Journal of Pharmaceutical Sciences · Cited by 2 · see citing works
Animal Models for Disorders of Circadian Functions
Davidson, A. J., & Turek, F. W. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-6645-3.00039-6 · Cited by 1 · see citing works
Health Effects of Shift Work and Night Shift Work
Guénel, P., & Léger, D. (2023) · Handbook series in occupational health sciences · doi:10.1007/978-3-030-94023-2_19-1 · Cited by 1 · see citing works
Chronobiology and Metabolic Syndrome: From Genes to Systems Biology
Sookoian, S., & Pirola, C. J. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5082-5_9
Self-citationFajardo, V. C. (2013) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
The Sleep-Wake Cycle and Circadian Rhythm Disruption: Shift Work and Cardiovascular Disease RiskPreprint
Ciechanowski, P. (2013) · SSRN Electronic Journal · doi:10.2139/ssrn.2312099
Circadian Rhythms and Cellular Networks in Cardiovascular Diseases
Yan, Q. (2015) · Springer eBooks · doi:10.1007/978-3-319-22819-8_5
Women’s Experience of Working Shiftwork in Nursing: A Phenomenological Study
Matheson, A. (2017) · Charles Sturt University Research Output (CRO)
Physiological consequence of sleep deprivation on healthy volunteers
El_Sawi, N., Edrees, M., & M., G. (2020) · Journal of Environmental Sciences. Mansoura University/Journal of Environmental Sciences. Mansoura University · doi:10.21608/joese.2020.158386
Hodeib, M., Meabed, M., Abougabal, K. M., & Etman, G. (2021) · The Egyptian Journal of Pediatric Allergy and Immunology · doi:10.21608/ejpa.2021.61225.1020
The Evolution of Human Circadian Rhythms: An Ancient Defence Mechanism Impacting Modern Life-Styles
Smith, D. J. M. (2022) · Medical Research Archives · doi:10.18103/mra.v10i7.2926
Kresna, A., Fuk, L. J., Widyahening, I. S., Soemarko, D. S., & Fitriani, D. Y. (2023) · Occupational and Environmental Medicine Journal of Indonesia · doi:10.7454/oemji.v1i2.1022
Shift work and early vascular aging: a systematic review
Xie, H.-L., Shu, L.-J., Cheng, R., Hu, M., & Liao, J.-W. (2026) · BMC Public Health · doi:10.1186/s12889-026-28426-6
- Authors
- Burgueño, A., Gemma, C., Gianotti, T. F., Sookoian, S., & Pirola, C. J.
- Affiliations
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Corresponding author
- Sookoian, Silvia
- Pirola, Carlos Jose
- Venue
- Atherosclerosis
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 210
- Issue
- 2
- Pages
- 625-629
- ISSN
- 0021-9150 (ISSN-L)
- OpenAlex
- W2037214255
- Cited by
- 53
- References
- 35
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 5 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 4 · 2013: 4 · 2012: 4
- FWCI
- 5.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Atherosclerosis (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Universidad de Buenos Aires (UBACYT M055)
- Agencia Nacional de Promoción Científica y Tecnológica (PICT 2004-25920, 2006-124)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- resistin, rotating shifts, circadian misalignment, cardiovascular risk, atherosclerosis biomarkers, soluble CD40 ligand, MCP-1, plasminogen activator inhibitor-1, white blood cell count, metabolic syndrome, young men
- MeSH terms
- Adult, Antibodies, Monoclonal, Cardiovascular Diseases, Cardiovascular System, Circadian Rhythm, Cross-Sectional Studies, Gene Expression Regulation, Humans, Male, Work Schedule Tolerance, Plasminogen Activator Inhibitor 1, Chemokine CCL2, CD40 Ligand, Atherosclerosis, Resistin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
