Testing a scalable web and smartphone based intervention to improve depression, anxiety, and resilience: A randomized controlled trial
Open accessAbstract
Psychological interventions targeting wellbeing can reliably increase wellbeing and decrease depressive symptoms.However, only a handful of studies have implemented wellbeing interventions online, and those studies have largely done so in a way that prioritizes experimental control over realism and scalability.We sought to take existing wellbeing interventions with established efficacy and to evaluate their impact when translated into a format that is publicly accessible, scalable, and designed with the goal of engaging users.Participants in this fully online trial were first-time registrants of the Happify platform, a fully automated web and mobile wellbeing intervention grounded in positive psychology, cognitivebehavioral therapy, and mindfulness-based stress reduction, which has offered wellbeing programs to over 3 million registrants to date.Consenting participants were randomly assigned to access the full Happify platform or a psychoeducation comparison condition and further categorized by their usage during the study: recommended usage (a minimum of 2-3 activities per week) or low usage (usage less than the recommended level).Participants were assessed on depressive symptoms, anxiety symptoms, and a composite measure of resilience at baseline and 8 weeks later.Participants who used Happify at the recommended level reported fewer depressive and anxiety symptoms and greater resilience after 8 weeks than participants who used Happify at a low level or participants who used the psychoeducation condition at any level.The Happify group also experienced greater rates of reduction in depression and anxiety symptom severity category, and had a greater net benefit (% users who improved minus % users who deteriorated), compared to the other groups.The results of this study suggest a successful first attempt at implementing and scaling a comprehensive package of lab-tested wellbeing interventions without losing efficacy.
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Deprexis uses CBT-based techniques and AI to personalize treatment and help patients with depression learn how to overcome negative thoughts and behavior patterns.
“Deprexis (developed by Orexo and GAIA) is a software platform that uses CBT-based techniques and AI to personalize treatment and help patients with depression learn how to overcome negative thoughts and behavior patterns”
From Digital health technologies and major depressive disorder (2023) · cites this paper as [94]
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Self-citation
- Authors
- Parks, A. C., Williams, A. L., Tugade, M. M., Hokes, K. E., Honomichl, R. D., & Zilca, R. D.
- Affiliations
- Case Western Reserve University (US)
- Corresponding author
- Parks, Acacia C.
- Venue
- International Journal of Wellbeing
- Publisher
- International Journal of Wellbeing
- Published
- 2018-12-08
- Volume
- 8
- Issue
- 2
- Pages
- 22-67
- ISSN
- 1179-8602 (ISSN-L)
- OpenAlex
- W2903748889
- Cited by
- 87
- References
- 83
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 7 · 2023: 7 · 2022: 4 · 2021: 51 · 2020: 5 · 2019: 3
- FWCI
- 18.63
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- International Journal of Wellbeing (publishedVersion, cc-by-nc-nd)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Keywords
- depression, anxiety, resilience, positive psychology, cognitive behavioral therapy, mindfulness-based stress reduction, mobile mental health, intervention scalability, user engagement, psychoeducation, net benefit
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