CoChat
Sign Up
Cited by 7

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Exposure to High Glucose Concentration Decreases Cell Surface ABCA1 and HDL Biogenesis in Hepatocytes

Tsujita, Maki, Hossain, Mohammad Anwar, Lu, Rui, Tsuboi, Tomoe, Okumura-Noji, Kuniko, Yokoyama, Shinji·2017·Journal of Atherosclerosis and Thrombosis
DOI 10.5551/jat.39156PMC PMC5684479
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.5551/jat.39156

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • When HDL generation by ABCA1 transporters at hepatocytes is compromised, VLDL secretion is rapidly reversed due to elevated triacylglycerol biogeneration in the liver.

    “It is thought that when HDL generation by ABCA1 transporters at hepatocytes is compromised, VLDL secretion is rapidly reversed due to elevated triacylglycerol biogeneration in the liver.22–26”

    From Clinical diversity and molecular mechanism of VPS35L-associated Ritscher-Schinzel syndrome (2023) · cites this paper as [22]

    The Introduction and Discussion (page unavailable) support the claim that hepatocyte surface ABCA1 enables HDL generation and that reduced surface ABCA1 impairs it. They do not say that compromised HDL generation rapidly reverses VLDL secretion or that increased hepatic triacylglycerol production causes such a change. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 57

  1. 1) Kannel WB, McGee DL: Diabetes and cardiovascular risk factors: the Framingham study, Circulation, 1979; 59: 8-13 · DOI · Paper page
  2. 2) Bierman EL: George Lyman Duff Memorial Lecture. Atherogenesis in diabetes, Arterioscler. Thromb., 1992; 12: 647-656 · DOI
  3. 3) Ginsberg HN: Lipoprotein physiology in nondiabetic and diabetic states. Relationship to atherogenesis, Diabetes Care, 1991; 14: 839-855 · DOI
  4. 4) Quintao EC, Medina WL, Passarelli M: Reverse cholesterol transport in diabetes mellitus, Diabetes Metab. Res. Rev., 2000; 16: 237-250
  5. 5) Kanter JE, Johansson F, LeBoeuf RC, Bornfeldt KE: Do Glucose and Lipids Exert Independent Effects on Atherosclerotic Lesion Initiation or Progression to Advanced Plaques?, Circ. Res., 2007; 100: 769-781
  6. 6) Coutinho M, Gerstein HC, Wang Y, Yusuf S: The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years, Diabetes Care, 1999; 22: 233-240 · DOI · Paper page
  7. 7) The DECODE study group on behalf of the European Diabetes Epidemiology Group: Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria, Arch. Intern. Med., 2001; 161: 397-405 · DOI · Paper page
  8. 8) Aronson D, Rayfield EJ: How hyperglycemia promotes atherosclerosis: molecular mechanisms, Cardiovasc. Diabetol., 2002; 1: 1
  9. 9) Laakso M, Barrett-Connor E: Asymptomatic hyperglycemia is associated with lipid and lipoprotein changes favoring atherosclerosis, Arteriosclerosis, 1989; 9: 665-672 · DOI
  10. 10) Forrest KY, Becker DJ, Kuller LH, Wolfson SK, Orchard TJ: Are predictors of coronary heart disease and lowerextremity arterial disease in type 1 diabetes the same? A prospective study, Atherosclerosis, 2000; 148: 159-169 · DOI
  11. 12) Wu JH, Foote C, Blomster J, Toyama T, Perkovic V, Sundstrom J, Neal B: Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: a systematic review and meta-analysis, Lancet Diabetes Endocrinol, 2016; Mar 18. doi: 1016/S2218-8587(1016) 00052-00058
  12. 13) Yokoyama S: Assembly of high-density lipoprotein, Arterioscler. Thromb. Vasc. Biol., 2006; 26: 20-27 · DOI
  13. 14) Hotta N, Abe-Dohmae S, Taguchi R, Yokoyama S: Preferential incorporation of shorter and less unsaturated acyl phospholipids into high density lipoprotein-like particles in the ABCA1- and ABCA7-mediated biogenesis with apoA-I, Chem Phys Lipids, 2015; 187: 1-9 · DOI
  14. 15) Brooks-Wilson A, Marcil M, Clee SM, Zhang LH, Roomp K, van Dam M, Yu L, Brewer C, Collins JA, Molhuizen HO, Loubser O, Ouelette BF, Fichter K, Ashbourne-Excoffon KJ, Sensen CW, Scherer S, Mott S, Denis M, Martindale D, Frohlich J, Morgan K, Koop B, Pimstone S, Kastelein JJ, Genest J, Jr., Hayden MR: Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency, Nat. Genet., 1999; 22: 336-345
  15. 16) Bodzioch M, Orso E, Klucken J, Langmann T, Bottcher A, Diederich W, Drobnik W, Barlage S, Buchler C, Porsch-Ozcurumez M, Kaminski WE, Hahmann HW, Oette K, Rothe G, Aslanidis C, Lackner KJ, Schmitz G: The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease, Nat. Genet., 1999; 22: 347-351
  16. 17) Rust S, Rosier M, Funke H, Real J, Amoura Z, Piette JC, Deleuze JF, Brewer HB, Duverger N, Denefle P, Assmann G: Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1, Nat. Genet., 1999; 22: 352-355
  17. 18) Assmann G, von Eckardstein A, Brewer HB, Jr., Familial Analphalipoproteinemia: Tangier Disease, in: C.R. Scriver, A.L. Beaudet, D. Valle, W.S. Sly (Eds.), The Metabolic and Molecular Basis of Inherited Disease (8th Edition), McGraw-Hill, New York, 2001, pp. 2937-2960
  18. 19) Tsujita M, Tomimoto S, Okumura-Noji K, Okazaki M, Yokoyama S: Apolipoprotein-mediated cellular cholesterol/phospholipid efflux and plasma high density lipoprotein level in mice, Biochim Biophys Acta, 2000; 1485: 199-213 · DOI
  19. 20) Tsujita M, Yokoyama S: Selective inhibition of free apolipoprotein-mediated cellular lipid efflux by probucol, Biochemistry, 1996; 35: 13011-13020 · DOI
  20. 21) Wu CA, Tsujita M, Hayashi M, Yokoyama S: Probucol inactivates ABCA1 in the plasma membrane with respect to its mediation of apolipoprotein binding and high density lipoprotein assembly and to its proteolytic degradation, J Biol Chem, 2004; 279: 30168-30174 · DOI
  21. 22) McNeish J, Aiello RJ, Guyot D, Turi T, Gabel C, Aldinger C, Hoppe KL, Roach ML, Royer LJ, de Wet J, Broccardo C, Chimini G, Francone OL: High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1, Proc. Natl. Acad. Sci. USA, 2000; 97: 4245-4250 · DOI
  22. 23) Vaisman BL, Lambert G, Amar M, Joyce C, Ito T, Shamburek RD, Cain WJ, Fruchart-Najib J, Neufeld ED, Remaley AT, Brewer HB, Jr., Santamarina-Fojo S: ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice, J.Clin. Invest., 2001; 108: 303-309
  23. 24) Basso F, Freeman L, Knapper CL, Remaley A, Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger N, Santamarina-Fojo S, Brewer HB, Jr.: Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations, J. Lipid Res., 2003; 44: 296-302
  24. 25) Tsujita M, Wu CA, Abe-Dohmae S, Usui S, Okazaki M, Yokoyama S: On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway, J. Lipid Res., 2005; 46: 154-162
  25. 26) Wang N, Tall AR: Regulation and mechanisms of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux, Arterioscler. Thromb. Vasc. Biol., 2003; 23: 1178-1184
  26. 27) Tamehiro N, Shigemoto-Mogami Y, Kakeya T, Okuhira K, Suzuki K, Sato R, Nagao T, Nishimaki-Mogami T: Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status, J Biol Chem, 2007; 282: 21090-21099 · DOI
  27. 28) Ohoka N, Okuhira K, Cui H, Wu W, Sato R, Naito M, Nishimaki-Mogami T: HNF4α increases liver-specific human ATP-binding cassette transporter A1 expression and cholesterol efflux to apolipoprotein A-I in response to cholesterol depletion, Arterioscler Thromb Vasc Biol, 2012; 32: 1005-1014 · DOI
  28. 29) Lu R, Arakawa R, Ito-Osumi C, Iwamoto N, Yokoyama S: ApoA-I facilitates ABCA1 recycle/accumulation to cell surface by inhibiting its intracellular degradation and increases HDL generation, Arterioscler Thromb Vasc Biol, 2008; 28: 1820-1824 · DOI
  29. 30) Arakawa R, Yokoyama S: Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation, J. Biol. Chem., 2002; 277: 22426-22429
  30. 31) Yokoyama S, Arakawa R, Wu CA, Iwamoto N, Lu R, Tsujita M, Abe-Dohmae S: Calpain-mediated ABCA1 degradation: post-translational regulation of ABCA1 for HDL biogenesis, Biochim Biophys Acta, 2012; 1821: 547-551 · DOI
  31. 32) Arakawa R, Tsujita M, Iwamoto N, Ito-Ohsumi C, Lu R, Wu CA, Shimizu K, Aotsuka T, Kanazawa H, Abe-Dohmae S, Yokoyama S: Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis, J Lipid Res, 2009; 50: 2299-2305 · DOI
  32. 33) Yakushiji E, Ayaori M, Nishida T, Shiotani K, Takiguchi S, Nakaya K, Uto-Kondo H, Ogura M, Sasaki M, Yogo M, Komatsu T, Lu R, Yokoyama S, Ikewaki K: ProbucolOxidized Products, Spiroquinone and Diphenoquinone, Promote Reverse Cholesterol Transport in Mice, Arterioscler Thromb Vasc Biol, 2016; 36: 591-597 · DOI
  33. 34) Lu R, Tsuboi T, Okumura-Noji K, Iwamoto N, Yokoyama S: Caveolin-1 facilitates internalization and degradation of ABCA1 and probucol oxidative products interfere with this reaction to increase HDL biogenesis, Atherosclerosis, 2016; 253: 54-60 · DOI
  34. 35) Kunjathoor VV, Wilson DL, LeBoeuf RC: Increased atherosclerosis in streptozotocin-induced diabetic mice, J. Clin. Invest., 1996; 97: 1767-1773
  35. 36) Morral N, Edenberg HJ, Witting SR, Altomonte J, Chu T, Brown M: Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver, J. Lipid Res., 2007; 48: 1499-1510
  36. 37) Noga AA, Stead LM, Zhao Y, Brosnan ME, Brosnan JT, Vance DE: Plasma homocysteine is regulated by phospholipid methylation, J. Biol. Chem., 2003; 278: 5952-5955
  37. 38) Gerdes LU, Gerdes C, Klausen IC, Faergeman O: Generation of analytic plasma lipoprotein profiles using two prepacked superose 6B columns, Clin. Chim. Acta, 1992; 205: 1-9
  38. 39) Hossain MA, Tsujita M, Gonzalez FJ, Yokoyama S: Effects of Fibrate Drugs on Expression of ABCA1 and HDL Biogenesis in Hepatocytes, J. Cardiovasc. Pharmacol., 2008; 51: 258-266
  39. 40) Chao CC, Yam WC, Lin-Chao S: Coordinated induction of two unrelated glucose-regulated protein genes by a calcium ionophore: human BiP/GRP78 and GAPDH, Biochem. Biophys. Res. Commun., 1990; 171: 431-438
  40. 41) Arakawa R, Hayashi M, Remaley AT, Brewer BH, Yamauchi Y, Yokoyama S: Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides, J Biol Chem, 2004; 279: 6217-6220 · DOI
  41. 42) Schwartz CJ, Valente AJ, Sprague EA, Kelley JL, Cayatte AJ, Rozek MM: Pathogenesis of the atherosclerotic lesion. Implications for diabetes mellitus, Diabetes Care, 1992; 15: 1156-1167 · DOI
  42. 43) Stamler J, Vaccaro O, Neaton JD, Wentworth D: Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial, Diabetes Care, 1993; 16: 434-444 · DOI · Paper page
  43. 44) The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus., New Engl. J. Med., 1993; 329: 977-986 · DOI · Paper page
  44. 45) Grundy SM, Benjamin IJ, Burke GL, Chait A, Eckel RH, Howard BV, Mitch W, Smith SC, Jr., Sowers JR: Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association, Circulation, 1999; 100: 1134-1146 · DOI · Paper page
  45. 46) Laakso M: Hyperglycemia and cardiovascular disease in type 2 diabetes, Diabetes, 1999; 48: 937-942 · DOI
  46. 47) Faulkner LE, Panagotopulos SE, Johnson JD, Woollett LA, Hui DY, Witting SR, Maiorano JN, Davidson WS: An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages, J. Lipid Res., 2008; in press, March 22 · DOI
  47. 48) Denis M, Landry YD, Zha X: ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurd at the plasma membrane and not in the endocytotic compartment, J. Biol. Chem., 2008; in press · DOI
  48. 49) Faulkner LE, Panagotopulos SE, Johnson JD, Woollett LA, Hui DY, Witting SR, Maiorano JN, Davidson WS: An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages, J Lipid Res, 2008; 49: 1322-1332 · DOI
  49. 50) Denis M, Landry YD, Zha X: ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurs at the plasma membrane and not in the endocytic compartments, J Biol Chem, 2008; 283: 16178-16186 · DOI
  50. 51) Okuhira K, Tsujita M, Yamauchi Y, Abe-Dohmae S, Kato K, Handa T, Yokoyama S: Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL, J Lipid Res, 2004; 45: 645-652 · DOI
  51. 52) Martins IJ, Redgrave TG: The effect of insulin deficiency on the plasma clearance and exchange of high-density-lipoprotein phosphatidylcholine in rats, Biochem. J., 1992; 281: 851-857
  52. 53) Hammad SM, Powell-Braxton L, Otvos JD, Eldridge L, Won W, Lyons TJ: Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy, Metabolism, 2003; 52: 916-921 · DOI
  53. 54) Tu A-Y, Albers JJ: Glucose regulates the transcription of human genes relevant to HDL metabolism: responsive elements for peroxisome proliferator-activated receptor are involved in the regulation of phospholipid transfer protein, Diabetes, 2001; 50: 1851-1856 · DOI
  54. 55) Uehara Y, Engel T, Li Z, Goepfert C, Rust S, Zhou X, Langer C, Schachtrup C, Wiekowski J, Lorkowski S, Assmann G, von Eckardstein A: Polyunsaturated fatty acids and acetoacetate downregulate the expression of the ATP-binding cassette transporter A1, Diabetes, 2002; 51: 2922-2928 · DOI
  55. 56) Passarelli M, Tang C, McDonald TO, O'Brien KD, Gerrity RG, Heinecke JW, Oram JF: Advanced glycation end product precursors impair ABCA1-dependent cholesterol removal from cells, Diabetes, 2005; 54: · DOI
  56. 57) Dentin R, Hedrick S, Xie J, Yates J, III., Montminy M: Hepatic glucose sensing via the CREB coactivator CRTC2, Science, 2008; 319: 1402-1405 · DOI
  57. 58) Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M: Identification of scavenger receptor SR-BI as a high density lipoprotein receptor, Science, 1996; 271: 518-520 · DOI · Paper page

Cited by

Sorted by citations

Metadata

Authors
Tsujita, M., Hossain, M. A., Lu, R., Tsuboi, T., Okumura-Noji, K., & Yokoyama, S.
Affiliations
  • Biochemistry, Nagoya City University Graduate School of Medical Sciences
  • Nutritional Health Science Research Center, Chubu University
Venue
Journal of Atherosclerosis and Thrombosis
Publisher
Japan Atherosclerosis Society
Published
2017
Volume
24
Issue
11
Pages
1132-1149
ISSN
  • 1340-3478
  • 1880-3873
DOI
10.5551/jat.39156
PMC
PMC5684479
Cited by
7
References
2
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review