Recommendations of the 4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD4)
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The 4th CCCDTD convened in May 2012 in Montreal with the primary aim of updating the previous diagnostic approach to AD, taking into account the revised diagnostic criteria proposed by the International Working Group (IWG) and the recommendations made by the National Institute on Aging-Alzheimer Association workgroups.
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Cholinesterase inhibitors (donepezil, galantamine, rivastigmine) and memantine are the only FDA-approved treatments for AD dementia.
“Cholinesterase inhibitors (ChEIs) (donepezil, galantamine, rivastigmine) and the N-methyl-D-aspartate (NMDA)-antagonist, memantine, are the only FDA-approved treatments for AD dementia and are recommended broadly in consensus guidelines and practice parameters.1,52,61,62”
From The Alzheimer’s Disease Clinical Spectrum (2019) · cites this paper as [62]
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“treatments for AD dementia and are recommended broadly in consensus guidelines and practice parameters.(1,52,61,62) ChEIs and memantine also have complementary mechanisms of action, potentially additive effects, and demonstrate acceptable tolerability and safety profiles.”
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Diagnostic Impact of Cerebrospinal Fluid Biomarkers in Atypical Dementias in Canada
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- Authors
- Gauthier, S., Patterson, C., Chertkow, H., Gordon, M., Herrmann, N., Rockwood, K., Rosa-Neto, P., & Soucy, J.-P.
- Affiliations
- McGill University (CA)
- McGill University Research Centre for Studies in Aging (CA)
- Corresponding author
- Gauthier, Serge
- ORCID
- Venue
- Canadian Geriatrics Journal
- Publisher
- Canadian Geriatrics Society
- Published
- 2012-09-20
- Volume
- 15
- Issue
- 4
- Pages
- 120-126
- ISSN
- 1925-8348 (ISSN-L)
- PMC
- PMC3516356
- OpenAlex
- W2153922623
- Cited by
- 137
- References
- 21
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 6 · 2023: 3 · 2022: 11 · 2021: 12 · 2020: 17 · 2019: 14 · 2018: 11 · 2017: 15 · 2016: 12 · 2015: 10 · 2014: 11 · 2013: 11
- FWCI
- 7.31
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Canadian Geriatrics Journal (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- American Academy of Neurology
- McGill University
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Cerebrospinal fluid and hydrocephalus
- Keywords
- dementia, Alzheimer's disease, dementia diagnosis, dementia treatment, diagnostic criteria, NIA-AA criteria, clinical guidelines
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