The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Superparamagnetic Iron Oxide Nanoparticles as MRI contrast agents for Non-invasive Stem Cell Labeling and Tracking
Open accessAbstract
Stem cells hold great promise for the treatment of multiple human diseases and disorders. Tracking and monitoring of stem cells in vivo after transplantation can supply important information for determining the efficacy of stem cell therapy. Magnetic resonance imaging (MRI) combined with contrast agents is believed to be the most effective and safest non-invasive technique for stem cell tracking in living bodies. Commercial superparamagnetic iron oxide nanoparticles (SPIONs) in the aid of transfection agents (TAs) have been applied to labeling stem cells. However, owing to the potential toxicity of TAs, more attentions have been paid to develop novel SPIONs with specific surface coating or functional moieties which facilitate effective cell internalization in the absence of TAs. This review aims to summarize the recent progress in the design and preparation of SPIONs as cellular MRI probes, to discuss their applications and current problems facing in stem cell labeling and tracking, and to offer perspectives and solutions for the future development of SPIONs in this field.
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Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., & Muller, R. N. (2008) · Chemical Reviews · doi:10.1021/cr068445e · Cited by 6,852
Doherty, G. J., & McMahon, H. T. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.78.081307.110540 · Cited by 3,075
In vivo MRI cell tracking: clinical studies
Bulte, J. W. M. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.09.3107 · Cited by 430
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Self-citationMagnetic tagging of therapeutic cells for MRI
Budde, M. D., & Frank, J. A. (2009) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.053546 · Cited by 78
Cited by
Ulbrich, K., Holá, K., Šubr, V., Bakandritsos, A., Tuček, J., & Zbořil, R. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00589 · Cited by 1,730
Wu, W., Wu, Z., Yu, T., Jiang, C., & Kim, W.-S. (2015) · Science and Technology of Advanced Materials · doi:10.1088/1468-6996/16/2/023501 · Cited by 1,574
Nguyen, M. D., Tran, H.-V., Xu, S., & Lee, T. R. (2021) · Applied Sciences · doi:10.3390/app112311301 · Cited by 783
Surface modification of magnetic iron oxide nanoparticles
Zhu, N., Ji, H., Yu, P., Niu, J., Farooq, M. U., Akram, M. W., Udego, I. O., Li, H., & Niu, X. (2018) · Nanomaterials · doi:10.3390/nano8100810 · Cited by 569
Kandasamy, G., & Maity, D. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.10.058 · Cited by 422
Metadata
- Authors
- Li, L., Jiang, W., Luo, K., Song, H., Lan, F., Wu, Y., & Gu, Z.
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2013
- Volume
- 3
- Issue
- 8
- Pages
- 595-615
- ISSN
- 1838-7640 (ISSN-L)
- OpenAlex
- W2117161686
- Cited by
- 491
- References
- 5
- FWCI
- 19.84
- Type
- journal article
- Language
- en
- Open access
- gold
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