The DOI matches its Crossref record.
Changes in energy balance and body composition at menopause: a controlled longitudinal study.
Abstract
OBJECTIVE: To describe the effects of menopause on resting metabolic rate, body composition, fat distribution, physical activity during leisure time, and fasting insulin levels. DESIGN: A longitudinal comparison of metabolic changes in women who experienced menopause with changes in age-matched women who did not experience menopause. SETTING: General clinical research center. PATIENTS: An initial cohort of 35 sedentary healthy premenopausal women (age range, 44 to 48 years). After 6 years of follow-up, 18 women had spontaneously stopped menstruating for at least 12 months and 17 women remained premenopausal. No women received hormone replacement therapy. RESULTS: Women who experienced menopause lost more fat-free mass than women who remained premenopausal (-3.0 +/- 1.1 kg and -0.5 +/- 0.5 kg, respectively), had greater decreases in resting metabolic rate (-103 +/- 55 kcal/d and -8 +/- 17 kcal/d) and physical activity during leisure time (-127 +/- 79 kcal/d and 64 +/- 60 kcal/d), and had greater increases in fat mass (2.5 +/- 2 kg and 1.0 +/- 1.5 kg), fasting insulin levels (11 +/- 9 pmol/L and -2 +/- 5 pmol/L), and waist-to-hip ratios (0.04 +/- 0.01 and 0.01 +/- 0.01) (P < or = 0.01 for all comparisons). Menopause did not affect energy intake, fasting glucose levels, or peak oxygen consumption. CONCLUSIONS: Natural menopause is associated with reduced energy expenditure during rest and physical activity, an accelerated loss of fat-free mass, and increased central adiposity and fasting insulin levels. These changes may indicate a worsening cardiovascular and metabolic risk profile.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“an age-related loss of muscle mass has been observed in women, this loss being particularly important at menopause (323,324).”
From Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone (2003) · cites this paper as [324]
Citations
Cited by
Sorted by citations
Items 201–300 of 518
Pathak, R. (2010) · The Open Anthropology Journal · doi:10.2174/1874912701003030172 · Cited by 33
Sarrafzadegan, N., Khosravi‐Boroujeni, H., Esmaillzadeh, A., Sadeghi, M., Rafieian‐Kopaei, M., & Asgary, S. (2013) · PubMed · Cited by 34
Effects of raloxifene on body fat distribution and lipid profile in healthy post-menopausal women
Francucci, C. M., Pantaleo, D., Iori, N., Camilletti, A., Massi, F., & Boscaro, M. (2005) · Journal of Endocrinological Investigation · doi:10.1007/bf03347261 · Cited by 34
Relationship between body mass index and mortality among Europeans
Song, X., Pitkäniemi, J. M., Gao, W., Heine, R. J., Pyörälà, K., Söderberg, S., Stehouwer, C. D. A., Zethelius, B., Tuomilehto, J. O., Laatikainen, T. K., et al. (2011) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2011.145 · Cited by 33
“Other potential confounders were also unavailable such as menopause status at baseline and body composition that could be very different between men and women and changes with menopause (Poehlman et al., 1995; Hoover and Boote, 2000).”
BackgroundPredicting visceral obesity based on facial characteristics
Lee, B. J., & Kim, J. Y. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-248 · Cited by 33
“Note that women who have experienced menopause show body shape changes and increased visceral adiposity [40-42] and that facial characteristics may differ according to gender and age [28,29].”
BackgroundArthur, F. K. N., Adu‐Frimpong, M., Osei-Yeboah, J., Mensah, F. O., & Owusu, L. (2012) · Lipids in Health and Disease · doi:10.1186/1476-511x-11-101 · Cited by 32
“The development of central obesity, insulin resistance as well as the worsening of glucose and lipid metabolism has been associated with menopause which results in an increased risk for cardiovascular disease [5,6].”
BackgroundTrp64Arg Variant of theβ 3-Adrenoceptor and Insulin Resistance in Obese Postmenopausal Women1
Garcı́a-Rubi, E., Starling, R. D., Tchernof, A., Matthews, D. E., Walston, J. D., Shuldiner, A. R., Silver, K. D., Poehlman, É. T., & Calles-Escandón, J. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.11.5225 · Cited by 33
Self-citationT cells in obesity‐associated inflammation: The devil is in the details
Valentine, Y. A., & Nikolajczyk, B. S. (2024) · Immunological Reviews · doi:10.1111/imr.13354 · Cited by 37
“65 Given that abdominal fat is particularly susceptible to the inflammation that supports insulin resistance, age-related shifts of adipose mass from (relatively protective) subcutaneous to visceral depots 66 compounds the effects of menopause on adipose tissue accumulation in women.”
Soy isoflavones, body composition, and physical performance
Kok, L., Kreijkamp‐Kaspers, S., Grobbee, D. E., Lampe, J. W., & van der Schouw, Y. T. (2005) · Maturitas · doi:10.1016/j.maturitas.2005.01.003 · Cited by 32
Terauchi, M., Obayashi, S., Akiyoshi, M., Kato, K., Matsushima, E., & Kubota, T. (2011) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2010.01424.x · Cited by 31
Bobescu, E., Bălan, A., Moga, M., Teodorescu, A., Mitrică, M., & Dima, L. (2020) · Marine Drugs · doi:10.3390/md18120651 · Cited by 35
“Perimenopause is mainly associated with fat redistribution, resulting in the transition from the gynoid to the android fat distribution pattern [24].”
BackgroundAnderson, E. J., Lavoie, H. B., Strauss, C. C., Hubbard, J. L., Sharpless, J. L., & Hall, J. E. (2001) · Metabolism · doi:10.1053/meta.2001.21015 · Cited by 31
Hansen, R., & Allen, B. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.2.314 · Cited by 31
Tankó, L. B., Movsesyan, L., Svendsen, O. L., & Christiansen, C. (2002) · Menopause · doi:10.1097/00042192-200203000-00006 · Cited by 30
“A recent study by Poehlman et al.(4) found an accelerated loss of fat-free lean tissue mass in women who became postmenopausal (0.”
ResultInfluentialTrevisan, M. C., & Burini, R. C. (2007) · Revista Brasileira de Medicina do Esporte · doi:10.1590/s1517-86922007000200013 · Cited by 30
Cao, Y., Zhang, S., Zou, S., & Xia, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058448 · Cited by 29
“Natural menopause is associated with increased abdominal fat that exceeds changes normally attributed to the aging process, primarily in the perimenopausal year [8,31,32].”
BackgroundLiang, H., Chen, X., Chen, Q., Wang, Y., Wu, X., Li, Y., Pan, B., Liu, H., & Li, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074121 · Cited by 29
“Some studies have reported a strong association between menopause and increased central adiposity [22] and blood pressure [23].”
BackgroundRole of Sex Hormones in the Control of Vegetative and Metabolic Functions of Middle-Aged Women
Monda, V., Salerno, M., Moscatelli, F., Villano, I., Viggiano, A., Sessa, F., Triggiani, A. I., Cibelli, G., Valenzano, A. A., Marsala, G., et al. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00773 · Cited by 30
“During menopause changing, the FM increased thanks to the TREE reduction; besides, they may enhance the occurrence of obesity-related diseases, especially related to worse cardiovascular risk profile (Poehlman et al., 1995) and Type II diabetes (Ravussin et al., 1988).”
BackgroundAn, C., Wang, H., Liu, X.-M., Li, Y., Su, Y., Gao, X., & JIANG, W. (2009) · Endocrine Journal · doi:10.1507/endocrj.k09e-096 · Cited by 29
Catalano, D., Trovato, G. M., Spadaro, D., Martines, G. F., Garufi, G., Tonzuso, A., Grasso, D., & Sciacchitano, S. (2008) · Climacteric · doi:10.1080/13697130802348728 · Cited by 29
Menopause, insulin resistance, and risk factors for cardiovascular disease
Manco, M., Nolfe, G., Calvani, M., Natali, A., Nolan, J. J., Ferrannini, E., & Mingrone, G. (2006) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000233492.38638.74 · Cited by 28
“Estrogens may promote insulin sensitivity and reduce cardiovascular risk in the long term by contrasting the visceral fat accumulation and favoring gluteal deposits.(24) Although experimental studies in animals have shown that estrogens increase glucose transport(27,28) and utilization in muscle cells,(26) in postmeno…”
BackgroundRelationship between uric acid and metabolic syndrome according to menopausal status
Lee, H. J., Park, H. T., Cho, G. J., et al. (2010) · Gynecological Endocrinology · doi:10.3109/09513590.2010.493962 · Cited by 29
“Many studies have shown that the menopausal transition is associated with a preferential increase in abdominal adiposity, suggesting that increased uric acid levels after menopause may be associated with increased visceral fat, as evaluated by WC [29,30].”
BackgroundLee, H. J., Hwang, S. Y., Hong, H. C., Ryu, J. Y., Seo, J. A., Kim, S. G., Kim, N. H., Choi, D. S., Baik, S. H., Choi, K. M., et al. (2015) · Maturitas · doi:10.1016/j.maturitas.2014.12.015 · Cited by 28
“[8] found hat natural postmenopausal women showed increased WHR when ompared with age-matched premenopausal women.”
BackgroundClinical correlates of sex hormones in women: The study of health in Pomerania
Kische, H., Groß, S., Wallaschofski, H., Völzke, H., Dörr, M., Nauck, M. A., & Haring, R. (2016) · Metabolism · doi:10.1016/j.metabol.2016.05.011 · Cited by 31
Kim, S.-K., Kwon, Y.-H., Cho, J. H., Lee, W., Park, S. E., Oh, H.-G., Park, C., Lee, W., Oh, K.-W., Park, S.-W., et al. (2017) · Endocrinology and Metabolism · doi:10.3803/enm.2017.32.4.442 · Cited by 29
Svendsen, O. L., & Hassager, C. (1998) · Metabolism · doi:10.1016/s0026-0495(98)90223-2 · Cited by 29
Association of Leptin: Adiponectin ratio and metabolic risk markers in postmenopausal women
Gupta, V., Gupta, V., Mishra, S., et al. (2018) · Immunology Letters · doi:10.1016/j.imlet.2018.01.008 · Cited by 28
Ogwumike, O. O., Adeniyi, A. F., & Orogbemi, O. O. (2015) · Hong Kong Physiotherapy Journal · doi:10.1016/j.hkpj.2015.06.001 · Cited by 28
“There are also body composition changes at menopause; some studies suggested increases in bodymass index (BMI) or total fatmasswithmenopause [7,9].”
BackgroundMasse, P. G., Dosy, J., Tranchant, C. C., & Dallaire, R. (2004) · Journal of Human Nutrition and Dietetics · doi:10.1111/j.1365-277x.2004.00508.x · Cited by 28
Maggi, S., Noale, M., Zambon, A., Limongi, F., Romanato, G., & Crepaldi, G. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.08.002 · Cited by 28
de Paz, I. P., Hernando, C. A., & Roldán, J. O. (2006) · PubMed · Cited by 28
Lin, C., Lin, Y., & Liu, C.-F. (2010) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x10008159 · Cited by 28
Gholizadeh, L., Salamonson, Y., Worrall‐Carter, L., DiGiacomo, M. L., & Davidson, P. M. (2009) · Journal of Women s Health · doi:10.1089/jwh.2008.0956 · Cited by 27
“33 The results are even more concerning when compared with national data.”
Primera encuesta nacional de sobrepeso y obesidad (ENSO I)
Pisabarro, R., Irrazábal, E., & Recalde, A. (2000) · Cited by 27
Toth, M. J., Sites, C. K., & Poehlman, É. T. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.8.5926 · Cited by 31
“5 kg 3 20 kcal/day/kg) or approximately 53% of the net reduction in resting energy expenditure observed during the menopause transition (295 kcal/day) (2).”
BackgroundResultInfluentialSelf-citationSuliga, E., Kozieł, D., Cieśla, E., Rębak, D., & Głuszek, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154511 · Cited by 28
Chronic loss of ovarian function decreases transport of leptin into mouse brain
Kastin, A. J., Akerstrom, V. L., & Maness, L. M. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02074-2 · Cited by 26
The poehlman case: running away from the truth
Dahlberg, J. E., & Mahler, C. C. (2006) · Science and Engineering Ethics · doi:10.1007/s11948-006-0016-9 · Cited by 26
Toth, M. J., Tchernof, A., Rosen, C. J., Matthews, D. E., & Poehlman, É. T. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.4.6533 · Cited by 27
“Based on our previous studies that showed a sharp decline in FFM during the menopause transition (3, 4), a period characterized by reduced ovarian hormone secretion, we hypothesized that circulating levels of estradiol, progesterone, or both would correlate to leucine turnover measurements.”
BackgroundSelf-citationYun, S., Nguyen, H. D., Park, J., Oh, C., & Kim, M. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521001331 · Cited by 25
Determinants of serum leptin levels in healthy postmenopausal women
Lambrinoudaki, I. V., Christodoulakos, G., Panoulis, C., Botsis, D. S., Rizos, D., Augoulea, A., & Creatsas, G. C. (2003) · Journal of Endocrinological Investigation · doi:10.1007/bf03349162 · Cited by 25
Majumdar, A. S., Giri, P. R., & Pai, S. A. (2014) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000000187 · Cited by 24
“Loss of estrogen with menopause promotes central fat deposition.(51) SIRT1 selectively controlled the remodeling of perigonadal white adipose tissue to the brown type, thereby increasing energy expenditure in female mice.”
BackgroundAging, fat oxidation and exercise
Calles-Escandón, J., & Poehlman, É. T. (1997) · Aging Clinical and Experimental Research · doi:10.1007/bf03340128 · Cited by 26
Self-citationYin, W., Maguire, S. M., Pham, B., Garcia, A. N., Dang, N.-V., Liang, J., Wolfe, A., Hofmann, H. A., & Gore, A. C. (2015) · Endocrinology · doi:10.1210/en.2015-1032 · Cited by 23
Upper extremity soft and rigid tissue mass prediction using segment anthropometric measures and DXA
Arthurs, K. L., & Andrews, D. M. (2009) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2008.11.021 · Cited by 23
Lambrinoudaki, I. V., Christodoulakos, G., Economou, E. V., Vlachou, S. A., Panoulis, C., Alexandrou, A. P., Kouskouni, E. E., & Creatsas, G. C. (2008) · Maturitas · doi:10.1016/j.maturitas.2007.10.003 · Cited by 23
Koshy, S. M., Bobby, Z., Hariharan, A. P., & Sridhar, M. G. (2012) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e31824e5bf7 · Cited by 23
“Natural menopause is associated with reduced energy expenditure during rest and physical activity, an accelerated loss of fat-free mass, and increased central adiposity.(45) In our study, ovariectomized rats had a rise in body weight without an increase in calorie intake (Table 1).”
BackgroundZhang, W., Chen, Q., Yuan, Z., Liu, J., Du, Z., Tang, F., Jia, H., Xue, F., & Zhang, C. (2015) · BMC Public Health · doi:10.1186/s12889-015-1424-z · Cited by 25
“Various studies indicated that natural menopause was associated with increased central adiposity [48], blood pressure [49-55], total cholesterol, LDL cholesterol and triglyceride levels [50,56], which would further increase”
BackgroundGültürk, S., Çetin, A., & Erdal, S. (2008) · Saudi Medical Journal · doi:10.15537/1658-3175.4353 · Cited by 23
Yang, Q., Song, C., Jiang, J., et al. (2017) · Hypertension Research · doi:10.1038/hr.2017.86 · Cited by 23
Lewis‐Barned, N., Wh, S., Walker, R., de Jong, S., Walker, H., Edwards, E., Markham, V., & Goulding, A. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.1650649 · Cited by 23
“Lower energy expenditure during rest and leisure-time physical activity in the face of unchanged energy intake may contribute to increased adiposity associated with natural menopause (Poehlman et al. 1995).”
BackgroundGaspard, U., Wery, O. J., Scheen, A. J., et al. (1999) · Climacteric · doi:10.3109/13697139909025572 · Cited by 23
Insulin sensitivity: Gender-related differences in subjects with normal glucose tolerance
Schianca, G. P. C., Castello, L. M., Rapetti, R., Limoncini, A., & Bartoli, E. (2005) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2005.05.004 · Cited by 22
Obesity and overweight in IMSS female workers in Mexico City
Vázquez-Martínez, J. L., Gómez‐Dantés, H., Gómez-García, F., et al. (2005) · Salud Pública de México · doi:10.1590/s0036-36342005000400003 · Cited by 22
Qader, S. S., Shakir, Y. A., Nyberg, P., & Samsioe, G. (2008) · Climacteric · doi:10.1080/13697130802451787 · Cited by 22
Clustering of cardiometabolic risk factors in Asian Indian women
Bhagat, M., Mukherjee, S., De, P., Goswami, R., Pal, S., Das, M., & Ghosh, A. K. (2010) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181bfac28 · Cited by 21
Martins-Maciel, E. R., Campos-Shimada, L. B., Salgueiro‐Pagadigorria, C. L., Bracht, A., & Ishii‐Iwamoto, E. L. (2012) · Toxicology Letters · doi:10.1016/j.toxlet.2012.11.021 · Cited by 21
Kuga, S., Njelekela, M. A., Noguchi, T., Kanda, T., Yamori, M., Sato, T., Miki, T., Ikeda, K., Nara, Y., & Mtabaji, J. (2002) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.29.s4.4.x · Cited by 21
The unfortunately long life of some retracted biomedical research publications
Hagberg, J. M. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00003.2020 · Cited by 21
Okura, T., Koda, M., Ando, F., Niino, N., & Shimokata, H. (2003) · Journal of PHYSIOLOGICAL ANTHROPOLOGY and Applied Human Science · doi:10.2114/jpa.22.47 · Cited by 21
“A longitudinal study [Poehlman et al., 1995] in American women showed that the normal menopausal transition decreased in REE by approximately 100 kcal/day compared to premenopausal women.”
BackgroundSubstrate utilization during exercise in postmenopausal women on hormone replacement therapy
Johnson, L., Kraemer, R., Kraemer, G., Haltom, R., Cordill, A., A.Welsch, M., Durand, R., & Castracane, D. (2002) · European Journal of Applied Physiology · doi:10.1007/s00421-002-0686-1 · Cited by 20
“All of these factors often contribute to the increased risk of cardiovascular and metabolic disease in postmenopausal women (Poehlman et al. 1995).”
BackgroundNoh, E., Kim, J., Kim, M., & Yi, E.-S. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186935 · Cited by 23
Cardiorespiratory Fitness and Body Composition in Postmenopausal Women
Moreira, H., Passos, B. M. A., Rocha, J. S. B., Reis, V. M. C. P., Carneiro, A. L. G., & Gabriel, R. (2014) · Journal of Human Kinetics · doi:10.2478/hukin-2014-0099 · Cited by 20
“Those changes in body composition are compounded by reduced levels of habitual physical activity and a basal metabolic rate (Poehlman et al., 1995), which contribute to worsening of cardiovascular fitness and the quality of life at this stage in life known as climacteric.”
BackgroundBody Fat Distribution Predicts Cardiac Risk Factors in Older Female Coronary Patients
Ross, S. J., Poehlman, É. T., Johnson, R. K., & Ades, P. A. (1997) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-199711000-00006 · Cited by 20
Self-citationFSH Level and Changes in Bone Mass and Body Composition in Older Women and Men
Wu, K. C., Ewing, S. K., Li, X., Sigurdsson, S. O., Gudnason, V. G., Kado, D. M., Hue, T. F., Woods, G. N., Veldhuis‐Vlug, A. G., Vittinghoff, E., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab481 · Cited by 22
Impact of triglycerides on lipid and lipoprotein biology in women
Dayspring, T. D., & Pokrywka, G. S. (2010) · Gender Medicine · doi:10.1016/j.genm.2010.05.002 · Cited by 19
Olorunshola, K. V., Toryila, J., & Achie, L. N. (2012) · Cited by 19
Yoldemir, T., & Erenus, M. (2012) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2012.06.021 · Cited by 19
“Loss of estrogen is associated with an increase in abdominal obesity, which may increase a woman’s risk for developing insulin resistance [30].”
BackgroundPredictive equations overestimate the resting metabolic rate in postmenopausal women
Bonganha, V., Libardi, C. A., dos Santos, C. F., et al. (2013) · The journal of nutrition health & aging · doi:10.1007/s12603-012-0395-3 · Cited by 18
Pitanga, C. P. S., Pitanga, F. J. G., Beck, C. C., Gabriel, R., & Moreira, M. H. R. (2012) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302012000600003 · Cited by 18
Orsatti, F. L., Nahás, E. A. P., Nahás-Neto, J., Maestá, N., Orsatti, C. L., Véspoli, H. D. L., & Traiman, P. (2009) · Gynecological Endocrinology · doi:10.3109/09513590903184076 · Cited by 18
ACTION OF LEPTIN ON BONE AND ITS RELATIONSHIP TO MENOPAUSE
Petzel, M. (2007) · Biomedical Papers · doi:10.5507/bp.2007.034 · Cited by 18
Yan, F., Liu, J., Zhao, X., Hu, X., Wang, S., Ma, Z., Liang, K., Song, J., Wang, C., Hou, X., et al. (2015) · Journal of Women s Health · doi:10.1089/jwh.2014.5183 · Cited by 18
“26 Similarly, our findings also show that postmenopausal women had a significantly higher mean WC, whereas there was no significant difference in BMI between pre-and postmenopausal women.”
Lemay, A., Turcot, L., Déchêne, F., Dodin, S., & Forest, J.-C. (2010) · Menopause · doi:10.1097/gme.0b013e3181b7c521 · Cited by 17
Yang, H. J., Kwon, D. Y., Kim, M. J., Kim, D. S., Kang, S., Shin, B. K., Lee, J. J., Moon, N. R., Daily, J. W., & Park, S. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.02.004 · Cited by 17
Wang, Q., Li, W., Zhou, Q.-H., et al. (2012) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x12500851 · Cited by 17
Terauchi, M., Hirose, A., Akiyoshi, M., et al. (2017) · Climacteric · doi:10.1080/13697137.2017.1293647 · Cited by 17
Nagamani, M., Szymajda, A., Sepilian, V., Urban, R. J., & Gilkison, C. R. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.03.083 · Cited by 17
Johnston, M., MacDonald, K., Manns, P. J., et al. (2011) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0b013e3181f1fd8c · Cited by 17
Saleh, J., Al-Khanbashi, M., Al-Maarof, M., Al-Lawati, M., Rizvi, S. G. A., & Cianflone, K. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0784 · Cited by 17
Rheumatoid Cachexia: causes, significance and possible interventions
Metsios, G. S., Kalinoglou, A. S., Koutedakis, Y., & Kitas, G. D. (2006) · Wolverhampton Intellectual Repository and E-Theses (University of Wolverhampton) · doi:10.2015/hc.v1i1.3 · Cited by 17
“REE accounts for 70% of DEE [33] and in normal individuals is highly depended on BCM [34].”
BackgroundInfluentialFood, energy and macronutrient intake of postmenopausal women from a menopause program.
Schoppen, S., Carbajal, Á., Pérez-Granados, A. M., Vivas, F., & Vaquero, M. P. (2005) · PubMed · Cited by 17
Change in diet and body mass index in Taiwanese women with length of residence in Australia.
Lee, W., Lingard, J. M., & Bermingham, M. (2007) · PubMed · Cited by 17
Impact of Obesity on Metabolic Syndrome among Adolescents as Compared with Adults in Korea
Kim, S., Lee, J., Nam, C. M., et al. (2011) · Yonsei Medical Journal · doi:10.3349/ymj.2011.52.5.746 · Cited by 16
Estradiol treatment improves biological rhythms in a preclinical rat model of menopause
Yin, W., Borniger, J. C., Wang, X., Maguire, S. M., Munselle, M. L., Bezner, K. S., Tesfamariam, H. M., Garcia, A. N., Hofmann, H. A., Nelson, R. J., et al. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.08.029 · Cited by 16
Orsatti, F. L., Nahás, E. A. P., Nahás-Neto, J., Maestá, N., Padoani, N. P., & Orsatti, C. L. (2008) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1590/s0100-72032008000400005 · Cited by 16
The Metabolic Syndrome in Women
Rosano, G. M. C., Vitale, C., & Mercuro, G. (2006) · Women s Health · doi:10.2217/17455057.2.6.889 · Cited by 18
“The increase and change in body fat distribution occurring after the menopause are directly related to the state of ovarian hormone deficiency, as women receiving hormone replacement therapy (HRT) gain weight to a lesser extent than women not receiving HRT [15,16].”
BackgroundInfluentialAdiponectin and Metabolic Syndrome in Women at Menopause.
Mańkowska‐Cyl, A., Nowak-Łoś, L., & Sypniewska, G. (2009) · PubMed Central · Cited by 17
Rouen, P. A., Lukacs, J. L., & Reame, N. E. (2010) · Biological Research For Nursing · doi:10.1177/1099800410365368 · Cited by 14
“…preservation of insulin sensitivity in early menopause in conjunction with the rise in AD is counterintuitive, given the reported increases in central adiposity associated with estrogen loss (Poehlman et al., 1995) and the inverse association of AD and IR with these fat depots (Cnop et al., 2003).”
Metabolic Syndrome Emerging from Menopause
Han, M. S. (2011) · Journal of Menopausal Medicine · doi:10.6118/jksm.2011.17.3.127 · Cited by 16
Study on Relation of Metabolic Syndrome with Menopause
Goyal, S., Baruah, M., Devi, R., et al. (2012) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-012-0243-6 · Cited by 15
“The metabolic syndrome (MS) consists of a constellation of metabolic abnormalities and a significant health care problem in postmenopausal women which increases risk of cardiovascular disease [1, 2] and type 2 diabetes mellitus [3].”
BackgroundKoo, B. K., Kim, S. W., Yi, K. H., & Moon, M. K. (2015) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2015.39.2.137 · Cited by 15
“As postmenopausal status is independently associated with abdominal obesity [22,23] and metabolic syndrome [24], we additionally adjusted menopausal state in the analysis of the women of KNHANES 2008 to 2010 and confirmed that only abdomiParameter Q1 Q2 Q3 Q4 P value 2009”
ResultRegulação da massa corpórea pelo estrogênio e pela atividade física
Ignacio, D. L., Frankenfeld, T. G. P., Fortunato, R. S., Vaisman, M., Werneck‐de‐Castro, J. P., & de Carvalho, D. P. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000300003 · Cited by 16
Lin, K., Tsay, S., Tsai, S., Kuo, S., & Chou, P. (2007) · The American Journal of the Medical Sciences · doi:10.1097/maj.0b013e31803bb22c · Cited by 15
Chu, M. C., Cushman, M., Solomon, R., & Løbo, R. A. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2008.04.033 · Cited by 16
Factors predisposing to obesity: a review of the literature
Ali, A. T., & Crowther, N. J. (2010) · South African Family Practice · doi:10.1080/20786204.2010.10873970 · Cited by 15
Chien, L.-W., Lin, M.-H., Chung, H., & Liu, C.-F. (2009) · Evidence-based Complementary and Alternative Medicine · doi:10.1093/ecam/nep145 · Cited by 15
“Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 862121, 7 pages doi:10.1093/ecam/nep145”
BackgroundInfluentialEffect of hormone replacement therapy and tibolone on serum leptin levels in postmenopausal women
Lambrinoudaki, I. V., Christodoulakos, G., Panoulis, C., Rizos, D., Dendrinos, S. G., Liakakos, T., Augoulea, A., & Creatsas, G. C. (2003) · Maturitas · doi:10.1016/j.maturitas.2003.07.001 · Cited by 15
“Menopause is usually associated with weight gain and body fat redistribution with central fat accumulation [11].”
BackgroundAasen, G., Fagertun, H., & Halse, J. (2009) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510902778734 · Cited by 14
“Studies using either DXA (dual X-ray absorptiometry), CT (computed tomography) (4) or waist-to-hip ratio (5) suggest that menopause is associated with accelerated accumulation of abdominal adipose tissue that is independent of age (6,7) and total body fatness (8,9), and can be observed even during the perimenopausal p…”
MethodRocha, J. S. B., Ogando, B. M. A. P., Reis, V. M. C. P., Ávila, W. R. D. M. E., Carneiro, A. G., Gabriel, R., & Moreira, M. H. R. (2012) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1590/s0100-72032012000900005 · Cited by 14
Metadata
- Authors
- Poehlman, E. T., Toth, M. J., & Gardner, A. W.
- Affiliations
- From the University of Maryland and Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
- University of Maryland, Baltimore (US)
- Baltimore VA Medical Center (US)
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1995-11-01
- Volume
- 123
- Issue
- 9
- Pages
- 673-675
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2072594041
- Cited by
- 520
- References
- 0
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 4 · 2023: 8 · 2022: 4 · 2021: 15 · 2020: 10 · 2019: 5 · 2018: 13 · 2017: 13 · 2016: 9 · 2015: 25 · 2014: 20 · 2013: 16 · 2012: 29
- FWCI
- 5.79
- Type
- journal article
- Language
- en
- Status
- Retracted
- Update notices
- retraction (2003-10-21)
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (7k04ag000564-06)
- National Institute on Aging (AG07857, T32AG00219, T32AG000219, KO4-AG00564)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Keywords
- menopause, energy balance, body composition, resting metabolic rate, fat-free mass loss, fat mass, abdominal obesity, waist-to-hip ratio, leisure-time physical activity, energy expenditure, fasting insulin, cardiovascular risk, metabolic risk, premenopausal women
- MeSH terms
- Adipose Tissue, Adult, Body Composition, Cardiovascular Diseases, Energy Metabolism, Fasting, Female, Humans, Insulin, Longitudinal Studies, Menopause, Middle Aged, Risk Factors, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
