Prevalence of Mental Health Disorders Among Adults With Cerebral Palsy: A Cross-sectional Analysis
Open accessAbstract
Background: Persons with cerebral palsy (CP) have an increased risk for secondary chronic conditions during childhood, including mental health disorders. However, little is known about how these disorders affect adults with CP. Objective: To determine the prevalence of mental health disorders among adults with CP compared with those without CP. Design: Cross-sectional. Setting: 2016 Optum Clinformatics Data Mart. Patients: 8.7 million adults (including 7348 adults with CP). Measurements: Other neurodevelopmental comorbid conditions (intellectual disabilities, autism spectrum disorders, epilepsy) and 37 mental health disorders (as 6 categories) were identified on the basis of diagnosis codes. Direct age-standardized prevalence of the mental health disorder categories was estimated by sex for adults with CP alone, adults with CP and neurodevelopmental disorders, and adults without CP. Results: Men with CP alone had higher age-standardized prevalence than men without CP for schizophrenic disorders (2.8% [95% CI, 2.2% to 3.4%] vs. 0.7%), mood affective disorders (19.5% [CI, 18.0% to 21.0%] vs. 8.1%), anxiety disorders (19.5% [CI, 18.0% to 21.0%] vs. 11.1%), disorders of adult personality and behavior (1.2% [CI, 0.8% to 1.6%] vs. 0.3%), and alcohol- and opioid-related disorders (4.7% [CI, 3.9% to 5.5%] vs. 3.0%). The same pattern was observed for women. Compared with adults with CP alone, those with CP and neurodevelopmental disorders had similar or higher age-standardized prevalence of the 6 mental health disorder categories, except for the lower prevalence of alcohol- and opioid-related disorders in men. Limitations: Single claims code was used to define the cohort of interest. Information on the severity of CP was not available. Conclusion: Compared with adults without CP, those with CP have an elevated prevalence of mental health disorders, some of which may be more pronounced in patients with comorbid neurodevelopmental disorders. Primary Funding Source: National Institute on Disability, Independent Living, and Rehabilitation Research.
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Adults with CP are at a higher risk of mental health diagnoses.
“Similarly to children, adults with CP are at a higher risk of mental health diagnoses [50,51].”
From The Mental Health of Children with Cerebral Palsy: A Review of the Last Five Years of Research (2025) · cites this paper as [51]
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Self-citation
- Authors
- Whitney, D. G., Warschausky, S. A., Ng, S., Hurvitz, E. A., Kamdar, N. S., & Peterson, M. D.
- Affiliations
- University of Michigan (US)
- ORCID
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 2019-09-03
- Volume
- 171
- Issue
- 5
- Pages
- 328-333
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- PMC
- PMC9704040
- OpenAlex
- W2964753358
- Cited by
- 93
- References
- 53
- Citations by year
- 2026: 8 · 2025: 15 · 2024: 10 · 2023: 13 · 2022: 12 · 2021: 16 · 2020: 14 · 2019: 5
- FWCI
- 9.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Cerebral Palsy and Movement Disorders
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
- Keywords
- cerebral palsy, mental illness, prevalence, adults, neurodevelopmental comorbidities, intellectual disability, autism spectrum disorder, epilepsy, schizophrenia, mood disorders, anxiety disorders, personality disorders, alcoholism, opioid use disorder, sex differences
- MeSH terms
- Adult, Mental Disorders, Cerebral Palsy, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Comorbidity, Prevalence, Sex Distribution, Neurodevelopmental Disorders
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