The Gut-Brain Axis: The Missing Link in Depression

Pattern Recognition Receptors and Inflammation

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Normal gut microbiota modulates brain development and behavior

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Regulation of short-chain fatty acid production

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The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

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Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: I. Optimization, Characterization, Brain Localization, and Cytotoxic Studies

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Me, my self, and the multitude: Microbiopolitics of the human microbiome

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The importance of gut-brain axis and use of probiotics as a treatment strategy for multiple sclerosis

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Probiotic Treatment in Individuals with Euthymic Bipolar Disorder: A Pilot-Study on Clinical Changes and Compliance

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Repeated mild traumatic brain injury affects microbial diversity in rat jejunum

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Emerging role of Gut-microbiota-brain axis in depression and therapeutic implication

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Adiponectin Role in Neurodegenerative Diseases: Focus on Nutrition Review

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Toll-like receptor expression and function in type I bipolar disorder

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The critical role of gut-brain axis microbiome in mental disorders

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Can microbiology affect psychiatry? A link between gut microbiota and psychiatric disorders

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Identification of intestinal and fecal microbial biomarkers using a porcine social stress model

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Ginger alleviates mechanical hypersensitivity and anxio-depressive behavior in rats with diabetic neuropathy through beneficial actions on gut microbiome composition, mitochondria, and neuroimmune cells of colon and spinal cord

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Psychobiotic Therapy: Method to Reinforce the Immune System

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Is There Any Link between Cognitive Impairment and Gut Microbiota? A Systematic Review

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Therapeutic Potential of the Microbiome in the Treatment of Neuropsychiatric Disorders

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Supplementation with soy isoflavones alleviates depression-like behaviour via reshaping the gut microbiota structure

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Mental Health Disorders Associated with Foodborne Pathogens

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Immune-Kynurenine Pathways and the Gut Microbiota-Brain Axis in Anxiety Disorders

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Modulation of Gut-Brain Axis by Probiotics: A Promising Anti-depressant Approach

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The Use of Prebiotic and Probiotic Interventions for Treating Gastrointestinal and Psychosocial Health Symptoms in Cancer Patients and Survivors: A Systematic Review

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Gut microbiota: A new target for traditional Chinese medicine in the treatment of depression

Li, B., Xu, M., Wang, Y., Feng, L., Xing, H., & Zhang, K. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.116038 · Cited by 35

Never fear, the gut bacteria are here: Estrogen and gut microbiome-brain axis interactions in fear extinction

Maeng, L. Y., & Beumer, A. (2023) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2023.05.350 · Cited by 31

Rifaximin ameliorates depression-like behaviour in chronic unpredictable mild stress rats by regulating intestinal microbiota and hippocampal tryptophan metabolism

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Neural, Anti-Inflammatory, and Clinical Effects of Transauricular Vagus Nerve Stimulation in Major Depressive Disorder: A Systematic Review

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Acupuncture may play a key role in anti-depression through various mechanisms in depression

Li, P., Zhao, J., Wei, X., Luo, L., Chu, Y., Zhang, T., Zhu, A., & Yan, J. (2024) · Chinese Medicine · doi:10.1186/s13020-024-00990-2 · Cited by 32

Efficacy of a postbiotic and its components in promoting colonic transit and alleviating chronic constipation in humans and mice

Ma, T., Li, Y., Yang, N., Wang, H., Shi, X., Liu, Y., Jin, H., Kwok, L., Sun, Z., & Zhang, H. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102093 · Cited by 31

Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway

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5-Fluorouracil induced dysregulation of the microbiome-gut-brain axis manifesting as depressive like behaviors in rats

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The relationship of interpersonal sensitivity and depression among patients with chronic atrophic gastritis: The mediating role of coping styles

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Fermented non-digestible fraction from combined nixtamalized corn (Zea mays L.)/cooked common bean (Phaseolus vulgaris L.) chips modulate anti-inflammatory markers on RAW 264.7 macrophages

Luzardo‐Ocampo, I., Campos-Vega, R., Cuéllar-Núñez, M. L., Vázquez‐Landaverde, P. A., Mojica, L., Gallegos, J. A. A., & Loarca-Piña, G. F. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.03.096 · Cited by 29

Jasmine tea extract prevents CUMS-induced depression-like behaviors through the modulation of microbiota-gut-brain axis

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Gut brain regulation using psychobiotics for improved neuropsychological illness

Deepika, Shukla, A. K., Kumari, A., & Kumar, A. (2023) · Developmental Psychobiology · doi:10.1002/dev.22404 · Cited by 28

Association between depression and enterovirus infection

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A Longitudinal Study of the Association Between Persistent Pathogens and Incident Depression Among Older U.S. Latinos

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A review on the relationship between gluten and schizophrenia: Is gluten the cause?

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Deciphering the compatibility rules of traditional Chinese medicine prescriptions based on NMR metabolomics: A case study of Xiaoyaosan

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The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial

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Fecal Metabolomics and Network Pharmacology Reveal the Correlations between Constipation and Depression

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Simultaneous Gut-Brain Electrophysiology Shows Cognition and Satiety Specific Coupling

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Efficacy of Probiotics on Anxiety: A Meta-analysis of Randomized Controlled Trials

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Partially hydrolyzed guar gum is associated with improvement in gut health, sleep, and motivation among healthy subjects

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Lactiplantibacillus plantarum CR12 attenuates chronic unforeseeable mild stress induced anxiety and depression-like behaviors by modulating the gut microbiota-brain axis

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Differences in the association between persistent pathogens and mood disorders among young- to middle-aged women and men in the U.S.

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Comorbid brain disorders associated with diabetes: therapeutic potentials of prebiotics, probiotics and herbal drugs

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Psychobiotics

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Graves’ disease as a driver of depression: a mechanistic insight

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Interactions between Bifidobacterium and Bacteroides and human milk oligosaccharides and their associations with infant cognition

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The role of the gut microbiome in disorders of gut–brain interaction

Gawey, B. J., Mars, R. A. T., & Kashyap, P. (2024) · FEBS Journal · doi:10.1111/febs.17200 · Cited by 30

Proteomic analysis of the intestine reveals SNARE-mediated immunoregulatory and amino acid absorption perturbations in a rat model of depression

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Tryptophan Metabolism: A New Look at the Role of Tryptophan Derivatives in the Human Body

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The Health and Clinical Benefits of Medicinal Fungi

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Engaging cognitive circuits to promote motor recovery in degenerative disorders. exercise as a learning modality

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Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants

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A Gut Feeling: The Importance of the Intestinal Microbiota in Psychiatric Disorders

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Oleoylethanolamide-producing Lactobacillus paracasei F19 improves metabolic and behavioral disorders by restoring intestinal permeability and microbiota-gut-brain axis in high-fat diet-induced obese male mice

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Ginsenoside Rb1 improves brain, lung, and intestinal barrier damage in middle cerebral artery occlusion/reperfusion (MCAO/R) micevia the PPARγ signaling pathway

Su, L., Yu-Chuan, R. E. N., Zhuo, C. H. E. N., Ma, H., ZHENG, F., Fang, L. I., Zhang, Y., Gong, S., & Kou, J. (2022) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(22)60204-8 · Cited by 19

Deciphering relationship between depression and microbial molecules based on multi-omics: A case study of Chaigui Granules

Wang, Q., Zhao, Y.-X., Qin, X., & Tian, J. (2024) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2023.12.003 · Cited by 19

A promising area of research in medicine: recent advances in properties and applications of Lactobacillus-derived exosomes

Liu, R. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1266510 · Cited by 19

Comprehensive review of depression detection techniques based on machine learning approach

Pinto, S. J., & Parente, M. (2024) · Soft Computing · doi:10.1007/s00500-024-09862-1 · Cited by 25

Differential expression of MHC- and macrophage-associated antigens in human fetal and postnatal small intestine.

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Surveying the Genetic Design Space for Transcription Factor-Based Metabolite Biosensors: Synthetic Gamma-Aminobutyric Acid and Propionate Biosensors in E. coli Nissle 1917

Lebovich, M., & Andrews, L. B. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.938056 · Cited by 17

Mechanism and implications of pro-nature physical activity in antagonizing psychological stress: the key role of microbial-gut-brain axis

Lou, H., Liu, X., & Liu, P. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1143827 · Cited by 20

The Intertwining Roads between Psychological Distress and Gut Microbiota in Inflammatory Bowel Disease

Gîlcă-Blanariu, G.-E., Șchiopu, C. G., Ștefănescu, G., Mihai, C., Diaconescu, S., Afrăsânie, V. A., Lupu, V. V., Lupu, A., Boloș, A., & Ștefănescu, C. (2023) · Microorganisms · doi:10.3390/microorganisms11092268 · Cited by 20

A domestic strain of Lactobacillus rhamnosus attenuates cognitive deficit and pro-inflammatory cytokine expression in an animal model of Alzheimer’s disease

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Psychoneuroimmunology and immunopsychiatry of zebrafish

de Abreu, M. S., Giacomini, A. C. V. V., Zanandrea, R., dos Santos, B. E., Genário, R., de Oliveira, G. G., Friend, A. J., Amstislavskaya, T. G., & Kalueff, A. V. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.03.014 · Cited by 19

Partially Hydrolyzed Guar Gum Modulates Gut Microbiota, Regulates the Levels of Neurotransmitters, and Prevents CUMS‐Induced Depressive‐Like Behavior in Mice

Chen, Y., Wan, M., Zhong, Y., Gao, T., Zhang, Y., Yan, F., Huang, D., Wu, Y., & Weng, Z. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202100146 · Cited by 19

Gut Microbiota as a Positive Potential Therapeutic Factor in Carcinogenesis: an Overview of Microbiota-Targeted Therapy

Joukar, F., Mavaddati, S., Mansour‐Ghanaei, F., & Samadani, A. A. (2019) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-019-00237-6 · Cited by 17

Genistein improves depression-like behavior in rats by regulating intestinal flora and altering glutamate gene expression

Ma, C., Zhang, F., Zhao, X., Yang, Y., Wang, B., Wang, Y., Liu, X.-F., Bian, X., Xu, Z., Zhang, G., et al. (2025) · Current Research in Food Science · doi:10.1016/j.crfs.2025.101020 · Cited by 16

Potential role of gut microbiota in major depressive disorder: A review

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The Association Between Adherence to the Mediterranean Diet and Depression and Anxiety Symptoms in University Students: The Mediating Role of Lean Mass and the Muscle Strength Index

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Unhealthy Behaviors Among Canadian Men Are Predictors of Comorbidities: Implications for Clinical Practice

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Could Physical Exercise Help Modulate the Gut Microbiota in Chronic Kidney Disease?

Esgalhado, M., Borges, N. A., & Mafra, D. (2016) · Future Microbiology · doi:10.2217/fmb.16.12 · Cited by 16

Associations of cMIND Diet with depressive and anxiety symptoms among old people in China: a nationwide study

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Electromagnetic field exposure-induced depression features could be alleviated by heat acclimation based on remodeling the gut microbiota

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Obesity and Depression: Common Link and Possible Targets

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Investigation of memory-enhancing effects of Streptococcus thermophilus EG007 in mice and elucidating molecular and metagenomic characteristics using nanopore sequencing

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Effects of chronic stress on intestinal amino acid pathways

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Initial Sequencing and Characterization of the Gastrointestinal and Oral Microbiota in Urban Pakistani Adults

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