Sowers, James R.

Diabetes and Cardiovascular Disease: A Statement for Healthcare Professionals From the American Heart Association

Grundy, S. M., Benjamin, I. J., Burke, G. L., Chait, A., Eckel, R. H., Howard, B. V., Mitch, W., Smith, S. C., & Sowers, J. R. (1999) · Circulation

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 2,698

Role of Mitochondrial Dysfunction in Insulin Resistance

Kim, J.-A., Wei, Y., & Sowers, J. R. (2008) · Circulation Research

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 1,103

Metformin: An Update

Kirpichnikov, D., McFarlane, S. I., & Sowers, J. R. (2002) · Annals of Internal Medicine

Diabetes Treatment and ManagementMetabolism, Diabetes, and Cancer

Cited by 1,084

Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases

Ren, J., Bi, Y., Sowers, J. R., Hetz, C., & Zhang, Y. (2021) · Nature Reviews Cardiology

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 708

Obesity as a cardiovascular risk factor

Sowers, J. R. (2003) · The American Journal of Medicine

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 584

The pathophysiology of hypertension in patients with obesity

DeMarco, V. G., Aroor, A. R., & Sowers, J. R. (2014) · Nature Reviews Endocrinology

Blood Pressure and Hypertension StudiesCardiovascular Disease and Adiposity

Cited by 545

Role of insulin resistance in endothelial dysfunction

Muniyappa, R., & Sowers, J. R. (2013) · Reviews in Endocrine and Metabolic Disorders

Nitric Oxide and Endothelin EffectsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 539

Obesity‐Related Hypertension: Pathogenesis, Cardiovascular Risk, and Treatment: A Position Paper of The Obesity Society and the American Society of Hypertension

Landsberg, L., Aronne, L. J., Beilin, L. J., Burke, V., Igel, L. I., Lloyd‐Jones, D., & Sowers, J. (2013) · The Journal of Clinical Hypertension

Blood Pressure and Hypertension StudiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 528

Endothelial cell senescence in aging-related vascular dysfunction

Jia, G., Aroor, A. R., Jia, C., & Sowers, J. R. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Telomeres, Telomerase, and SenescenceNitric Oxide and Endothelin Effects

Cited by 454

The metabolic syndrome: role of skeletal muscle metabolism.

Stump, C. S., Henriksen, E. J., Wei, Y., & Sowers, J. R. (2006) · Annals of Medicine

Diabetes, Cardiovascular Risks, and LipoproteinsAdipose Tissue and Metabolism

Cited by 362

Narrative Review: The Emerging Clinical Implications of the Role of Aldosterone in the Metabolic Syndrome and Resistant Hypertension

Sowers, J. R., Whaley-Connell, A., & Epstein, M. (2009) · Annals of Internal Medicine

Hormonal Regulation and HypertensionRenin-Angiotensin System Studies

Cited by 351

Targeting autophagy in obesity: from pathophysiology to management

Zhang, Y., Sowers, J. R., & Ren, J. (2018) · Nature Reviews Endocrinology

Autophagy in Disease and TherapyAdipokines, Inflammation, and Metabolic Diseases

Cited by 338

Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance

Cooper, S. A., Whaley-Connell, A., Habibi, J., Wei, Y., Lastra, G., Manrique, C., Stas, S., & Sowers, J. R. (2007) · American Journal of Physiology-Heart and Circulatory Physiology

Renin-Angiotensin System StudiesNitric Oxide and Endothelin Effects

Cited by 317

Type 2 Diabetes Mellitus and Hypertension

Lastra, G., Syed, S., Kurukulasuriya, L. R., Manrique, C., & Sowers, J. R. (2014) · Endocrinology and Metabolism Clinics of North America

Blood Pressure and Hypertension StudiesRenin-Angiotensin System Studies

Cited by 307

Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: Time for a critical appraisal

Accurso, A., Bernstein, R. K., Dahlqvist, A., Draznin, B., Feinman, R. D., Fine, E. J., Gleed, A., Jacobs, D. B., Larson, G., Lustig, R. H., et al. (2008) · Nutrition & Metabolism

Diet and metabolism studiesDietary Effects on Health

Cited by 263

Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-κB activation via NADPH oxidase

Wei, Y., Sowers, J. R., Clark, S. E., Li, W., Ferrario, C. M., & Stump, C. S. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Renin-Angiotensin System StudiesAdipokines, Inflammation, and Metabolic Diseases

Cited by 197

Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression

Blendea, M. C., Jacobs, D., Stump, C. S., McFarlane, S. I., Ogrin, C., Bahtyiar, G., Stas, S., Kumar, P., Sha, Q., Ferrario, C. M., et al. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Renin-Angiotensin System StudiesNitric Oxide and Endothelin Effects

Cited by 171

The Renin Angiotensin Aldosterone System in Obesity and Hypertension

Cabandugama, P. K., Gardner, M. J., & Sowers, J. R. (2017) · Medical Clinics of North America

Renin-Angiotensin System StudiesEicosanoids and Hypertension Pharmacology

Cited by 168

Role of the Sympathetic Nervous System in Blood Pressure Maintenance in Obesity

SOWERS, J. R., WHITFIELD, L. A., CATANIA, R. A., STERN, N., TUCK, M. L., DORNFELD, L., & MAXWELL, M. (1982) · The Journal of Clinical Endocrinology & Metabolism

Blood Pressure and Hypertension StudiesRenin-Angiotensin System Studies

Cited by 162

Overnutrition, mTOR signaling, and cardiovascular diseases

Jia, G., Aroor, A. R., Martinez-Lemus, L. A., & Sowers, J. R. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 122

Diabetes, hypertension, and cardiovascular derangements: Pathophysiology and management

El-Atat, F., McFarlane, S. I., & Sowers, J. R. (2004) · Current Hypertension Reports

Blood Pressure and Hypertension StudiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 121

Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat

Lastra, G., Whaley-Connell, A., Manrique, C., Habibi, J., Gutweiler, A. A., Appesh, L., Hayden, M. R., Wei, Y., Ferrario, C., & Sowers, J. R. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Hormonal Regulation and HypertensionRenin-Angiotensin System Studies

Cited by 119

Nebivolol Improves Diastolic Dysfunction and Myocardial Remodeling Through Reductions in Oxidative Stress in the Zucker Obese Rat

Zhou, X., Ma, L., Habibi, J., Whaley-Connell, A., Hayden, M. R., Tilmon, R. D., Brown, A. N., Kim, J.-A., DeMarco, V. G., & Sowers, J. R. (2010) · Hypertension

Cardiovascular Function and Risk FactorsCardiac Fibrosis and Remodeling

Cited by 116

Diabetes and Cardiovascular Disease: an Update

Almourani, R., Chinnakotla, B., Patel, R., Kurukulasuriya, L. R., & Sowers, J. (2019) · Current Diabetes Reports

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 114