Polleux, Franck

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Toyama, E. Q., Herzig, S., Courchet, J., Lewis, T. L., Losón, O. C., Hellberg, K., Young, N. P., Chen, H., Polleux, F., Chan, D. C., et al. (2016) · Science

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,085

Establishment of axon-dendrite polarity in developing neurons.

Barnes, A. P., & Polleux, F. (2009) · Annual Review of Neuroscience

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 523

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation

Suzuki, I. K., Gacquer, D., Van Heurck, R., Kumar, D., Wojno, M., Bilheu, A., Herpoel, A., Lambert, N., Cheron, J., Polleux, F., et al. (2018) · Cell

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 471

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation

Charrier, C., Joshi, K., Coutinho-Budd, J., Kim, J.-E., Lambert, N., de Marchena, J., Jin, W.-L., Vanderhaeghen, P., Ghosh, A., Sassa, T., et al. (2012) · Cell

Neurogenesis and neuroplasticity mechanismsGenetics and Neurodevelopmental Disorders

Cited by 454

KCC2 Expression Promotes the Termination of Cortical Interneuron Migration in a Voltage-Sensitive Calcium-Dependent Manner

Bortone, D., & Polleux, F. (2009) · Neuron

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 387

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

Mairet-Coello, G., Courchet, J., Pieraut, S., Courchet, V., Maximov, A., & Polleux, F. (2013) · Neuron

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 351

TGF-β Signaling Specifies Axons during Brain Development

Yi, J. J., Barnes, A. P., Hand, R., Polleux, F., & Ehlers, M. D. (2010) · Cell

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 284

MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size

Lewis, T. L., Kwon, S.-K., Lee, A., Shaw, R., & Polleux, F. (2018) · Nature Communications

Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research

Cited by 260

Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity

Turner, N. L., Macrina, T., Bae, J. A., Yang, R., Wilson, A. M., Schneider-Mizell, C., Lee, K., Lu, R., Wu, J., Bodor, A. L., et al. (2022) · Cell

Neuroscience and Neuropharmacology ResearchCell Image Analysis Techniques

Cited by 206

Developmental mechanisms underlying the evolution of human cortical circuits

Vanderhaeghen, P., & Polleux, F. (2023) · Nature Reviews Neuroscience

Neurogenesis and neuroplasticity mechanismsGenetics and Neurodevelopmental Disorders

Cited by 173

Transcriptional regulation of vertebrate axon guidance and synapse formation

Polleux, F., Ince-Dunn, G., & Ghosh, A. (2007) · Nature Reviews Neuroscience

Axon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology Research

Cited by 168

Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex

Ebrahimi-Fakhari, D., Saffari, A., Wahlster, L., Di Nardo, A., Turner, D., Lewis, T. L., Conrad, C., Rothberg, J. M., Lipton, J. O., Kölker, S., et al. (2016) · Cell Reports

Autophagy in Disease and TherapyTuberous Sclerosis Complex Research

Cited by 146

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses

Fossati, M., Pizzarelli, R., Schmidt, E. R., Kupferman, J. V., Stroebel, D., Polleux, F., & Charrier, C. (2016) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 133

AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

Williams, T., Courchet, J., Viollet, B., Brenman, J. E., & Polleux, F. (2011) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsMetabolism, Diabetes, and Cancer

Cited by 123

Netrin-1–α3β1 integrin interactions regulate the migration of interneurons through the cortical marginal zone

Stanco, A., Szekeres, C., Patel, N., Rao, S., Campbell, K., Kreidberg, J. A., Polleux, F., & Anton, E. S. (2009) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal Signaling

Cited by 118

A human-specific modifier of cortical connectivity and circuit function

Schmidt, E. R. E., Zhao, H. T., Park, J. M., Dipoppa, M., Monsalve-Mercado, M. M., Dahan, J. B., Rodgers, C. C., Lejeune, A., Hillman, E. M. C., Miller, K. D., et al. (2021) · Nature

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 82

A cell‐autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration

Ferguson, K. L., McClellan, K. A., Vanderluit, J. L., McIntosh, W. C., Schuurmans, C., Polleux, F., & Slack, R. S. (2005) · The EMBO Journal

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 65

AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology

Tilokani, L., Russell, F. M., Hamilton, S., Virga, D. M., Segawa, M., Paupe, V., Gruszczyk, A. V., Protasoni, M., Tabara, L.-C., Johnson, M., et al. (2022) · Science Advances

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 60

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development

Schmidt, E. R. E., Kupferman, J. V., Stackmann, M., & Polleux, F. (2019) · Scientific Reports

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 55

Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

Libé-Philippot, B., Iwata, R., Recupero, A. J., Wierda, K., Bernal Garcia, S., Hammond, L., van Benthem, A., Limame, R., Ditkowska, M., Beckers, S., et al. (2024) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 38

Impaired Mitochondrial Dynamics And Mitophagy In Neuronal Models Of Tuberous Sclerosis Complex

Ebrahimi-Fakhari, D., Saffari, A., Wahlster, L., DiNardo, A., Turner, D., Lewis, T. L., Conrad, C., Rothberg, J. M., Lipton, J. O., Kölker, S., et al. (2016) · Cell Reports

Tuberous Sclerosis Complex ResearchAutophagy in Disease and Therapy

Cited by 23

Neuronal Morphogenesis: Golgi Outposts, Acentrosomal Microtubule Nucleation, and Dendritic Branching

Lewis, T. L., & Polleux, F. (2012) · Neuron

Microtubule and mitosis dynamicsNeurogenesis and neuroplasticity mechanisms

Cited by 9