Spector, Tim D.
King's College London · ZOE (United Kingdom)
117 papers on CoChatORCID 0000-0002-9795-0365
Most cited papers
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Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma
Lee, K. A., Thomas, A. M., Bolte, L. A., Björk, J. R., de Ruijter, L. K., Armanini, F., Asnicar, F., Blanco-Miguez, A., Board, R., Calbet-Llopart, N., et al. (2022) · Nature Medicine
Cancer Immunotherapy and BiomarkersGut microbiota and health
Cited by 464
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Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
Broer, L., Codd, V., Nyholt, D. R., Deelen, J., Mangino, M., Willemsen, G., Albrecht, E., Amin, N., Beekman, M., de Geus, E. J. C., et al. (2013) · European Journal of Human Genetics
Telomeres, Telomerase, and SenescenceGenetic Associations and Epidemiology
Cited by 450
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The person-to-person transmission landscape of the gut and oral microbiomes
Valles-Colomer, M., Blanco-Míguez, A., Manghi, P., Asnicar, F., Dubois, L., Golzato, D., Armanini, F., Cumbo, F., Huang, K. D., Manara, S., et al. (2023) · Nature
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 449
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Are Twins and Singletons Comparable? A Study of Disease-related and Lifestyle Characteristics in Adult Women
Andrew, T., Hart, D. J., Snieder, H., de Lange, M., Spector, T. D., & MacGregor, A. J. (2001) · Twin Research
Assisted Reproductive Technology and Twin PregnancyGenetic Associations and Epidemiology
Cited by 440
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Signatures of early frailty in the gut microbiota
Jackson, M. A., Jeffery, I. B., Beaumont, M., Bell, J. T., Clark, A. G., Ley, R. E., O’Toole, P. W., Spector, T. D., & Steves, C. J. (2016) · Genome Medicine
Gut microbiota and healthFrailty in Older Adults
Cited by 436
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Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach
Menni, C., Fauman, E., Erte, I., Perry, J. R. B., Kastenmüller, G., Shin, S.-Y., Petersen, A.-K., Hyde, C., Psatha, M., Ward, K. J., et al. (2013) · Diabetes
Metabolomics and Mass Spectrometry StudiesDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 416
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Low‐level increases in serum C‐reactive protein are present in early osteoarthritis of the knee and predict progressive disease
Spector, T. D., Hart, D. J., Nandra, D., Doyle, D. V., Mackillop, N., Gallimore, J. R., & Pepys, M. B. (1997) · Arthritis & Rheumatism
Osteoarthritis Treatment and MechanismsRheumatoid Arthritis Research and Therapies
Cited by 403
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
The PRACTICAL Consortium, Day, F. R., kConFab Investigators, AOCS Investigators, Scotland, G., EPIC-InterAct Consortium, Study, L. C., Ruth, K. S., Thompson, D. J., Lunetta, K. L., et al. (2015) · Nature Genetics
Genetic Associations and EpidemiologyBRCA gene mutations in cancer
Cited by 402
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A DNA methylation biomarker of alcohol consumption
Liu, C., Marioni, R. E., Hedman, Å. K., Pfeiffer, L., Tsai, P.-C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., et al. (2018) · Molecular Psychiatry
Epigenetics and DNA MethylationAlcohol Consumption and Health Effects
Cited by 402
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Glycans Are a Novel Biomarker of Chronological and Biological Ages
Krištić, J., Vučković, F., Menni, C., Klarić, L., Keser, T., Beceheli, I., Pučić-Baković, M., Novokmet, M., Mangino, M., Thaqi, K., et al. (2014) · The Journals of Gerontology: Series A
Glycosylation and Glycoproteins ResearchAdvanced Glycation End Products research
Cited by 400
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A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., et al. (2019) · Nature Communications
Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging
Cited by 362
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Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci
Demerath, E. W., Guan, W., Grove, M. L., Aslibekyan, S., Mendelson, M., Zhou, Y.-H., Hedman, Å. K., Sandling, J. K., Li, L.-A., Irvin, M. R., et al. (2015) · Human Molecular Genetics
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 355
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A twin approach to unraveling epigenetics
Bell, J. T., & Spector, T. D. (2011) · Trends in Genetics
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 353
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Common variants near TERC are associated with mean telomere length
Wellcome Trust Case Control Consortium, Codd, V., Mangino, M., van der Harst, P., Braund, P. S., Kaiser, M., Beveridge, A. J., Rafelt, S., Moore, J., Nelson, C., et al. (2010) · Nature Genetics
Telomeres, Telomerase, and SenescenceGenetic Associations and Epidemiology
Cited by 344
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Human serum metabolic profiles are age dependent
Yu, Z., Zhai, G., Singmann, P., He, Y., Xu, T., Prehn, C., Römisch‐Margl, W., Lattka, E., Gieger, C., Soranzo, N., et al. (2012) · Aging Cell
Metabolomics and Mass Spectrometry StudiesGenetics, Aging, and Longevity in Model Organisms
Cited by 340
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Quantitative variability of 342 plasma proteins in a human twin population
Liu, Y., Buil, A., Collins, B. C., Gillet, L. C., Blum, L. C., Cheng, L., Vitek, O., Mouritsen, J., Lachance, G., Spector, T. D., et al. (2015) · Molecular Systems Biology
Genetic Associations and EpidemiologyAdvanced Proteomics Techniques and Applications
Cited by 328
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Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
Tsaprouni, L. G., Yang, T.-P., Bell, J., Dick, K. J., Kanoni, S., Nisbet, J., Viñuela, A., Grundberg, E., Nelson, C. P., Meduri, E., et al. (2014) · Epigenetics
Epigenetics and DNA MethylationSmoking Behavior and Cessation
Cited by 319
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Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study
Graham, M. S., Sudre, C. H., May, A., Antonelli, M., Murray, B., Varsavsky, T., Kläser, K., Canas, L. S., Molteni, E., Modat, M., et al. (2021) · The Lancet Public Health
SARS-CoV-2 and COVID-19 ResearchCOVID-19 epidemiological studies
Cited by 304
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The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis
Roederer, M., Quaye, L., Mangino, M., Beddall, M. H., Mahnke, Y., Chattopadhyay, P., Tosi, I., Napolitano, L., Terranova Barberio, M., Menni, C., et al. (2015) · Cell
Genetic Associations and EpidemiologyT-cell and B-cell Immunology
Cited by 296
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Meta-analysis of genome-wide association data identifies two loci influencing age at menarche
Perry, J. R. B., Stolk, L., Franceschini, N., Lunetta, K. L., Zhai, G., McArdle, P. F., Smith, A. V., Aspelund, T., Bandinelli, S., Boerwinkle, E., et al. (2009) · Nature Genetics
Hypothalamic control of reproductive hormonesGenetic Associations and Epidemiology
Cited by 294
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Genetic evidence for causal relationships between maternal obesity-related traits and birth weight
Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrustry, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., et al. (2016) · JAMA
Birth, Development, and HealthGestational Diabetes Research and Management
Cited by 284
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Metabolomic markers reveal novel pathways of ageing and early development in human populations
Menni, C., Kastenmüller, G., Petersen, A. K., Bell, J. T., Psatha, M., Tsai, P.-C., Gieger, C., Schulz, H., Erte, I., John, S., et al. (2013) · International Journal of Epidemiology
Metabolomics and Mass Spectrometry StudiesBirth, Development, and Health
Cited by 282
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Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene ( AUTS2 ) in the regulation of alcohol consumption
Schumann, G., Coin, L. J., Lourdusamy, A., Charoen, P., Berger, K. H., Stacey, D., Desrivières, S., Aliev, F. A., Khan, A. A., Amin, N., et al. (2011) · Proceedings of the National Academy of Sciences
Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior
Cited by 264
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Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology
Levy, D., Neuhausen, S. L., Hunt, S. C., Kimura, M., Hwang, S.-J., Chen, W., Bis, J. C., Fitzpatrick, A. L., Smith, E., Johnson, A. D., et al. (2010) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceGenetic Associations and Epidemiology
Cited by 259
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