Spector, Tim D.

Whole-genome sequence-based analysis of thyroid function

Taylor, P. N., Porcu, E., Chew, S., Campbell, P. J., Traglia, M., Brown, S. J., Mullin, B. H., Shihab, H. A., Min, J., Walter, K., et al. (2015) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 104

Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure

Visconti, A., Duffy, D. L., Liu, F., Zhu, G., Wu, W., Chen, Y., Hysi, P. G., Zeng, C., Sanna, M., Iles, M. M., et al. (2018) · Nature Communications

melanin and skin pigmentationGenetic Associations and Epidemiology

Cited by 103

Dietary magnesium Is positively associated with skeletal muscle power and indices of muscle mass and may attenuate the association between circulating C-Reactive Protein and muscle mass in women

Welch, A. A., Kelaiditi, E., Jennings, A., Steves, C. J., Spector, T. D., & MacGregor, A. (2016) · Journal of Bone and Mineral Research

Magnesium in Health and DiseaseNutrition and Health in Aging

Cited by 100

DNA methylation studies using twins: what are they telling us?

Bell, J. T., & Spector, T. D. (2012) · Genome Biology

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 89

’Anxiety and depression symptoms after COVID-19 infection: results from the COVID Symptom Study app ’

Klaser, K., Thompson, E. J., Nguyen, L. H., Sudre, C. H., Antonelli, M., Murray, B., Canas, L. S., Molteni, E., Graham, M. S., Kerfoot, E., et al. (2021) · Journal of Neurology, Neurosurgery & Psychiatry

COVID-19 and Mental HealthLong-Term Effects of COVID-19

Cited by 84

An investigation into physical frailty as a link between the gut microbiome and cognitive health

Verdi, S., Jackson, M. A., Beaumont, M., Bowyer, R. C. E., Bell, J. T., Spector, T. D., & Steves, C. J. (2018) · Frontiers in Aging Neuroscience

Gut microbiota and healthFrailty in Older Adults

Cited by 82

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

Drong, A. W., Nicholson, G., Hedman, Å. K., Meduri, E., Grundberg, E., Small, K. S., Shin, S.-Y., Bell, J. T., Karpe, F., Soranzo, N., et al. (2013) · PLoS ONE

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 79

The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study

Drake, W. M., Rodríguez‐Arnao, J., Weaver, J. U., James, I. T., Coyte, D., Spector, T. D., Besser, G. M., & Monson, J. P. (2001) · Clinical Endocrinology

Growth Hormone and Insulin-like Growth FactorsBone health and osteoporosis research

Cited by 76

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

Crawford, A. A., Bankier, S., Altmaier, E., Barnes, C. L. K., Clark, D. W., Ermel, R., Friedrich, N., van der Harst, P., Joshi, P. K., Karhunen, V., et al. (2021) · Journal of Human Genetics

Genetic Associations and EpidemiologyStress Responses and Cortisol

Cited by 74

Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study

Zhai, G., Aviv, A., Hunter, D. J., Hart, D. J., Gardner, J. P., Kimura, M., Lu, X., Valdes, A. M., & Spector, T. D. (2006) · Annals of the Rheumatic Diseases

Osteoarthritis Treatment and MechanismsTelomeres, Telomerase, and Senescence

Cited by 72

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model

Zierer, J., Pallister, T., Tsai, P.-C., Krumsiek, J., Bell, J. T., Lauc, G., Spector, T. D., Menni, C., & Kastenmüller, G. (2016) · Scientific Reports

Bioinformatics and Genomic NetworksGenetics, Aging, and Longevity in Model Organisms

Cited by 63

Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits

Boraska, V., Davis, O. S. P., Cherkas, L. F., Helder, S. G., Harris, J., Krug, I., Pei‐Chi Liao, T., Treasure, J., Ntalla, I., Karhunen, L., et al. (2012) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Eating Disorders and BehaviorsGenetic Associations and Epidemiology

Cited by 61

Statins as modulators of bone formation

Edwards, C. J., & Spector, T. D. (2002) · Arthritis Research & Therapy

Bone health and osteoporosis researchBone Metabolism and Diseases

Cited by 53

Validity of continuous glucose monitoring for categorizing glycemic responses to diet: implications for use in personalized nutrition

Merino, J., Linenberg, I., Bermingham, K. M., Ganesh, S., Bakker, E., Delahanty, L. M., Chan, A. T., Capdevila Pujol, J., Wolf, J., Al Khatib, H., et al. (2022) · The American Journal of Clinical Nutrition

Diabetes Management and ResearchNutrition, Genetics, and Disease

Cited by 46

Machine learning integration of multimodal data identifies key features of blood pressure regulation

Louca, P., Tran, T. Q. B., Toit, C. D., Christofidou, P., Spector, T. D., Mangino, M., Suhre, K., Padmanabhan, S., & Menni, C. (2022) · EBioMedicine

Blood Pressure and Hypertension StudiesSodium Intake and Health

Cited by 37

Personalised REsponses to DIetary Composition Trial (PREDICT): an intervention study to determine inter-individual differences in postprandial response to foods

Berry, S., Drew, D., Linenberg, I., Wolf, J., Hadjigeorgiou, G., Davies, R., Khatib, H. A., Hart, D., Surdulescu, G., Yarand, D., et al. (2020)

Nutrition, Genetics, and DiseaseMetabolomics and Mass Spectrometry Studies

Cited by 33

Geo-social gradients in predicted COVID-19 prevalence in Great Britain: results from 1 960 242 users of the COVID-19 Symptoms Study app

Bowyer, R. C. E., Varsavsky, T., Thompson, E. J., Sudre, C. H., Murray, B. A. K., Freidin, M. B., Yarand, D., Ganesh, S., Capdevila, J., Bakker, E., et al. (2021) · Thorax

COVID-19 epidemiological studiesData-Driven Disease Surveillance

Cited by 24

Twin studies advance the understanding of gene-environment interplay in human nutrigenomics

Pallister, T., Spector, T. D., & Menni, C. (2014) · Nutrition Research Reviews

Nutrition, Genetics, and DiseaseGenetic Associations and Epidemiology

Cited by 20

Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With KLF9 and DOT1L

Lafontaine, N., Campbell, P. J., Castillo-Fernandez, J. E., Mullin, S., Lim, E. M., Kendrew, P., Lewer, M., Brown, S. J., Huang, R.-C., Melton, P. E., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism

Epigenetics and DNA MethylationThyroid Disorders and Treatments

Cited by 17

Optimised Glucose “Time in Range” Using Continuous Glucose Monitors in 4,805 Non-Diabetic Individuals Is Associated With Favourable Diet and Health: The ZOE PREDICT Studies

Berry, S., Bermingham, K., Valdes, A., Franks, P., Wolf, J., & Spector, T. (2022) · Current Developments in Nutrition

Diabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 4