Gribble, Fiona M.

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

Zhang, Q., Ramracheya, R., Lahmann, C., Tarasov, A., Bengtsson, M., Braha, O., Braun, M., Brereton, M., Collins, S., Galvanovskis, J., et al. (2013) · Cell Metabolism

Pancreatic function and diabetesIon channel regulation and function

Cited by 225

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, J. J., Reimann, F., & Gribble, F. M. (2016) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 223

Preproglucagon neurons in the nucleus of the solitary tract are the main source of brain GLP-1, mediate stress-induced hypophagia, and limit unusually large intakes of food

Holt, M. K., Richards, J. E., Cook, D. R., Brierley, D. I., Williams, D. L., Reimann, F., Gribble, F. M., & Trapp, S. (2019) · Diabetes

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 212

Metabolic messengers: glucagon-like peptide 1

Gribble, F. M., & Reimann, F. (2021) · Nature Metabolism

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 199

Preproglucagon neurons project widely to autonomic control areas in the mouse brain

Llewellyn-Smith, I. J., Reimann, F., Gribble, F. M., & Trapp, S. (2011) · Neuroscience

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 194

The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo

Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, J. J., et al. (2014) · Cell Metabolism

Neuropeptides and Animal PhysiologyRegulation of Appetite and Obesity

Cited by 179

MgATP activates the β cell K ATP channel by interaction with its SUR1 subunit

Gribble, F. M., Tucker, S. J., Haug, T., & Ashcroft, F. M. (1998) · Proceedings of the National Academy of Sciences

Ion channel regulation and functionPancreatic function and diabetes

Cited by 171

Activation of the GLP-1 Receptors in the Nucleus of the Solitary Tract Reduces Food Reward Behavior and Targets the Mesolimbic System

Richard, J. E., Anderberg, R. H., Göteson, A., Gribble, F. M., Reimann, F., & Skibicka, K. P. (2015) · PLOS ONE

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 168

The Interaction of nucleotides with the tolbutamide block of cloned atp‐sensitive k+ channel currents expressed in xenopus oocytes: a reinterpretation

Gribble, F. M., Tucker, S. J., & Ashcroft, F. M. (1997) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 161

Molecular mechanisms underlying nutrient-stimulated incretin secretion

Parker, H. E., Reimann, F., & Gribble, F. M. (2010) · Expert Reviews in Molecular Medicine

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 155

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Vergari, E., Knudsen, J. G., Ramracheya, R., Salehi, A., Zhang, Q., Adam, J., Asterholm, I. W., Benrick, A., Briant, L. J. B., Chibalina, M. V., et al. (2019) · Nature Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 152

The intestine as an endocrine organ and the role of gut hormones in metabolic regulation

Bany Bakar, R., Reimann, F., & Gribble, F. M. (2023) · Nature Reviews Gastroenterology & Hepatology

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 144

Mechanism of Cloned ATP-sensitive Potassium Channel Activation by Oleoyl-CoA

Gribble, F. M., Proks, P., Corkey, B. E., & Ashcroft, F. M. (1998) · Journal of Biological Chemistry

Ion channel regulation and functionPancreatic function and diabetes

Cited by 133

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells

Hodge, D., Glass, L. L., Diakogiannaki, E., Pais, R., Lenaghan, C., Smith, D. M., Wedin, M., Bohlooly-Y, M., Gribble, F. M., & Reimann, F. (2016) · Peptides

Diabetes Treatment and ManagementBiochemical Analysis and Sensing Techniques

Cited by 99

Na+ current properties in islet α‐ and β‐cells reflect cell‐specific Scn3a and Scn9a expression

Zhang, Q., Chibalina, M. V., Bengtsson, M., Groschner, L. N., Ramracheya, R., Rorsman, N. J. G., Leiss, V., Nassar, M. A., Welling, A., Gribble, F. M., et al. (2014) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 90

Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding

Adriaenssens, A., Broichhagen, J., de Bray, A., Ast, J., Hasib, A., Jones, B., Tomas, A., Burgos, N. F., Woodward, O., Lewis, J., et al. (2023) · JCI Insight

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 77

Signalling in the gut endocrine axis

Gribble, F. M., & Reimann, F. (2017) · Physiology & Behavior

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 66

Selective stimulation of colonic L cells improves metabolic outcomes in mice

Lewis, J. E., Miedzybrodzka, E. L., Foreman, R. E., Woodward, O. R. M., Kay, R. G., Goldspink, D. A., Gribble, F. M., & Reimann, F. (2020) · Diabetologia

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 59

GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Based Therapies in Treating Metabolic Disorders

Samms, R. J., Sloop, K. W., Gribble, F. M., Reimann, F., & Adriaenssens, A. E. (2021) · Diabetes

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 49

A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion

Montaner, M., Denom, J., Simon, V., Jiang, W., Holt, M. K., Brierley, D. I., Rouch, C., Foppen, E., Kassis, N., Jarriault, D., et al. (2024) · Nature Communications

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 36

A unique olfactory bulb microcircuit driven by neurons expressing the precursor to glucagon-like peptide 1

Thiebaud, N., Gribble, F., Reimann, F., Trapp, S., & Fadool, D. A. (2019) · Scientific Reports

Olfactory and Sensory Function StudiesNeuroscience and Neuropharmacology Research

Cited by 34

Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression

Wagner, S., Brierley, D. I., Leeson-Payne, A., Jiang, W., Chianese, R., Lam, B. Y. H., Dowsett, G. K. C., Cristiano, C., Lyons, D., Reimann, F., et al. (2023) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 32

Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice

Hammoud, R., Kaur, K. D., Koehler, J. A., Baggio, L. L., Wong, C. K., Advani, K. E., Yusta, B., Efimova, I., Gribble, F. M., Reimann, F., et al. (2025) · JCI Insight

Diabetes Treatment and ManagementInflammatory Bowel Disease

Cited by 24