Signalling in the gut endocrine axis

The Physiology of Glucagon-like Peptide 1

Holst, J. J. (2007) · Physiological Reviews · doi:10.1152/physrev.00034.2006 · Cited by 3,371 · see citing works

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2

Tolhurst, G., Heffron, H., Lam, Y. S., Parker, H. E., Habib, A. M., Diakogiannaki, E., Cameron, J., Grosse, J., Reimann, F., & Gribble, F. M. (2012) · Diabetes · doi:10.2337/db11-1019 · Cited by 2,404 · see citing works

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

Nauck, M. A., Heimesaat, M. M., Orskov, C., Holst, J. J., Ebert, R., & Creutzfeldt, W. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116186 · Cited by 1,651 · see citing works

Inhibition of Food Intake in Obese Subjects by Peptide YY _3–36

Batterham, R. L., Cohen, M. A., Ellis, S. M., Le Roux, C. W., Withers, D. J., Frost, G. S., Ghatei, M. A., & Bloom, S. R. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030204 · Cited by 1,604 · see citing works

FXR is a molecular target for the effects of vertical sleeve gastrectomy

Ryan, K. K., Tremaroli, V., Clemmensen, C., Kovatcheva-Datchary, P., Myronovych, A., Karns, R., Wilson-Pérez, H. E., Sandoval, D. A., Kohli, R., Bäckhed, F., et al. (2014) · Nature · doi:10.1038/nature13135 · Cited by 931 · see citing works

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

Psichas, A., Sleeth, M. L., Murphy, K. G., Brooks, L., Bewick, G. A., Hanyaloglu, A. C., Ghatei, M. A., Bloom, S. R., & Frost, G. (2015) · International Journal of Obesity · doi:10.1038/ijo.2014.153 · Cited by 886 · see citing works

Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses

NAUCK, M. A., HOMBERGER, E., SIEGEL, E. G., ALLEN, R. C., EATON, R. P., EBERT, R., & CREUTZFELDT, W. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-63-2-492 · Cited by 874 · see citing works

Glucose Sensing in L Cells: A Primary Cell Study

Reimann, F., Habib, A. M., Tolhurst, G., Parker, H. E., Rogers, G. J., & Gribble, F. M. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.11.002 · Cited by 733 · cited 5× · see citing works

Na+-<scp>d</scp>-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

Gorboulev, V., Schürmann, A., Vallon, V., Kipp, H., Jaschke, A., Klessen, D., Friedrich, A., Scherneck, S., Rieg, T., Cunard, R., et al. (2012) · Diabetes · doi:10.2337/db11-1029 · Cited by 687 · see citing works

Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium

Gribble, F. M., & Reimann, F. (2016) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105439 · Cited by 683 · see citing works

The Cardiovascular Biology of Glucagon-like Peptide-1

Drucker, D. J. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.06.009 · Cited by 665 · see citing works

Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells

Chimerel, C., Emery, E., Summers, D. K., Keyser, U., Gribble, F. M., & Reimann, F. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.10.032 · Cited by 548 · cited 2× · see citing works

Endocrine cells in human intestine: an immunocytochemical study

Sjölund, K., Sandén, G., Håkanson, R., & Sundler, F. (1983) · Gastroenterology · doi:10.1016/s0016-5085(83)80080-8 · Cited by 520 · see citing works

Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

Vilsbøll, T., Krarup, T., Madsbad, S., & Holst, J. J. (2003) · Regulatory Peptides · doi:10.1016/s0167-0115(03)00111-3 · Cited by 430 · see citing works

GPR119 Is Essential for Oleoylethanolamide-Induced Glucagon-Like Peptide-1 Secretion From the Intestinal Enteroendocrine L-Cell

Lauffer, L. M., Iakoubov, R., & Brubaker, P. L. (2009) · Diabetes · doi:10.2337/db08-1237 · Cited by 400 · see citing works

A Novel Glucose-Sensing Mechanism Contributing to Glucagon-Like Peptide-1 Secretion From the GLUTag Cell Line

Gribble, F. M., Williams, L., Simpson, A. K., & Reimann, F. M. (2003) · Diabetes · doi:10.2337/diabetes.52.5.1147 · Cited by 394 · see citing works

Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP

Theodorakis, M. J., Carlson, O. D., Michopoulos, S., Doyle, M. E., Juhaszova, M., Petraki, K., & Egan, J. M. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00326.2004 · Cited by 391 · see citing works

A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release

Chu, Z., Carroll, C., Alfonso, J., Gutierrez, V., He, H., Lucman, A., Pedraza, M., Mondala, H., Gao, H., Bagnol, D., et al. (2008) · Endocrinology · doi:10.1210/en.2007-0966 · Cited by 387 · see citing works

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

Habib, A. M., Richards, P., Cairns, L. S., Rogers, G. J., Bannon, C. A. M., Parker, H. E., Morley, T. C. E., Yeo, G. S. H., Reimann, F. M., & Gribble, F. M. (2012) · Endocrinology · doi:10.1210/en.2011-2170 · Cited by 382 · see citing works

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

Brighton, C. A., Rievaj, J., Kuhre, R. E., Glasssmith, L. L., Schoonjans, K., Holst, J. J., Gribble, F. M., & Reimann, F. M. (2015) · Endocrinology · doi:10.1210/en.2015-1321 · Cited by 355 · see citing works

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

Egerod, K. L., Engelstoft, M. S., Grunddal, K. V., Nøhr, M. K., Secher, A., Sakata, I., Pedersen, J., Windeløv, J. A., Füchtbauer, E., Olsen, J., et al. (2012) · Endocrinology · doi:10.1210/en.2012-1595 · Cited by 328 · see citing works

Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells

Parker, H. E., Habib, A. M., Rogers, G. J., Gribble, F. M., & Reimann, F. (2009) · Diabetologia · doi:10.1007/s00125-008-1202-x · Cited by 324 · see citing works

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

Engelstoft, M. S., Park, W.-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S. L., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., et al. (2013) · Molecular Metabolism · doi:10.1016/j.molmet.2013.08.006 · Cited by 318 · see citing works

Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance

Jørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, D., Lindqvist Hansen, D., et al. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00073.2012 · Cited by 313 · see citing works

Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line

Drucker, D. J., Jin, T., Asa, S. L., Young, T. A., & Brubaker, P. L. (1994) · Molecular Endocrinology · doi:10.1210/mend.8.12.7535893 · Cited by 303 · see citing works

Glucose-Sensing in Glucagon-Like Peptide-1-Secreting Cells

Reimann, F. M., & Gribble, F. M. (2002) · Diabetes · doi:10.2337/diabetes.51.9.2757 · Cited by 293 · see citing works

Exaggerated Glucagon-Like Peptide 1 Response Is Important for Improved β-Cell Function and Glucose Tolerance After Roux-en-Y Gastric Bypass in Patients With Type 2 Diabetes

Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, D., Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, S., & Holst, J. J. (2013) · Diabetes · doi:10.2337/db13-0022 · Cited by 279 · see citing works

The G-Protein−Coupled Receptor GPR40 Directly Mediates Long-Chain Fatty Acid−Induced Secretion of Cholecystokinin

Liou, A. P., Lu, X., Sei, Y., Zhao, X., Pechhold, S. B., Carrero, R. J., Raybould, H. E., & Wank, S. A. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.10.012 · Cited by 276 · see citing works

Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects

Ma, J., Bellon, M., Wishart, J. M., Young, R. L., Blackshaw, L. A., Jones, K. L., Horowitz, M., & Rayner, C. K. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.90708.2008 · Cited by 256 · see citing works

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Reimann, F. M., Williams, L., Xavier, G. D. S., Rutter, G. A., & Gribble, F. M. (2004) · Diabetologia · doi:10.1007/s00125-004-1498-0 · Cited by 251 · see citing works

The regulation of K‐ and L‐cell activity by GLUT2 and the calcium‐sensing receptor CasR in rat small intestine

Mace, O. J., Schindler, M., & Patel, S. J. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2011.223800 · Cited by 247 · see citing works

Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion

Parker, H. E., Adriaenssens, A. E., Rogers, G. J., Richards, P., Koepsell, H., Reimann, F. M., & Gribble, F. M. (2012) · Diabetologia · doi:10.1007/s00125-012-2585-2 · Cited by 212 · see citing works

The role of gut hormones in the regulation of body weight and energy homeostasis

Karra, E., & Batterham, R. L. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.06.010 · Cited by 210 · see citing works

GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

Hauge, M., Vestmar, M. A., Husted, A. S., Ekberg, J. H., Wright, M., Salvo, J. D., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, M., et al. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.10.002 · Cited by 209 · see citing works

Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor

Diakogiannaki, E., Pais, R., Tolhurst, G., Parker, H. E., Horscroft, J. A., Rauscher, B., Zietek, T., Daniel, H., Gribble, F. M., & Reimann, F. M. (2013) · Diabetologia · doi:10.1007/s00125-013-3037-3 · Cited by 200 · see citing works

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo

Fujita, Y., Wideman, R. D., Speck, M., Asadi, A., King, D., Webber, T. D., Haneda, M., & Kieffer, T. J. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90636.2008 · Cited by 196 · see citing works

Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Wewer Albrechtsen, N. J., Rehfeld, J. F., Hartmann, B., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.121 · Cited by 185 · see citing works

Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+ and cAMP

Tolhurst, G., Zheng, Y., Parker, H. E., Habib, A. M., Reimann, F. M., & Gribble, F. M. (2011) · Endocrinology · doi:10.1210/en.2010-0956 · Cited by 177 · see citing works

Cholecystokinin and gut–brain signalling

Dockray, G. J. (2009) · Regulatory Peptides · doi:10.1016/j.regpep.2009.03.015 · Cited by 168 · see citing works

The G Protein-coupled Receptor Family C Group 6 Subtype A (GPRC6A) Receptor Is Involved in Amino Acid-induced Glucagon-like Peptide-1 Secretion from GLUTag Cells

Oya, M., Kitaguchi, T., Pais, R., Reimann, F. M., Gribble, F. M., & Tsuboi, T. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.402677 · Cited by 167 · see citing works

Generation of L Cells in Mouse and Human Small Intestine Organoids

Petersen, N., Reimann, F. M., Bartfeld, S., Farin, H. F., Ringnalda, F. C. A. S., Vries, R. G. J., van den Brink, S., Clevers, H. C., Gribble, F. M., & de Koning, E. J. P. (2013) · Diabetes · doi:10.2337/db13-0991 · Cited by 156 · see citing works

High fat diet impairs the function of glucagon-like peptide-1 producing L-cells

Richards, P., Pais, R., Habib, A. M., Brighton, C. A., Yeo, G. S. H., Reimann, F. M., & Gribble, F. M. (2015) · Peptides · doi:10.1016/j.peptides.2015.06.006 · Cited by 142 · see citing works

Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes

Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, J. J., Deacon, C. F., Gallwitz, B., Schmidt, W. E., & Meier, J. J. (2004) · Regulatory Peptides · doi:10.1016/j.regpep.2004.06.020 · Cited by 137 · see citing works

Duodenal Enteroendocrine I-Cells Contain mRNA Transcripts Encoding Key Endocannabinoid and Fatty Acid Receptors

Sykaras, A. G., Demenis, C., CASE, R. M., McLaughlin, J. T., & Smith, C. P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042373 · Cited by 122 · see citing works

Peptide production and secretion in GLUTag, NCI-H716, and STC-1 cells: a comparison to native L-cells

Kuhre, R. E., Albrechtsen, N. J. W., Deacon, C. F., Balk-Møller, E., Rehfeld, J. F., Reimann, F. M., Gribble, F. M., & Holst, J. J. (2016) · Journal of Molecular Endocrinology · doi:10.1530/jme-15-0293 · Cited by 118 · see citing works

Gastrin-releasing peptide is a novel mediator of proximal nutrient- induced proglucagon-derived peptide secretion from the distal gut

Roberge, J. N., Gronau, K. A., & Brubaker, P. L. (1996) · Endocrinology · doi:10.1210/endo.137.6.8641190 · Cited by 117 · see citing works

Effects of JNJ‐38431055, a novel GPR119 receptor agonist, in randomized, double‐blind, placebo‐controlled studies in subjects with type 2 diabetes

Katz, L., Gambale, J. J., Rothenberg, P., Vanapalli, S. R., Vaccaro, N. M., Xi, L., Sarich, T. C., & Stein, P. P. (2012) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2012.01587.x · Cited by 110 · see citing works

Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum

Ritzel, U., Fromme, A., Ottleben, M., Leonhardt, U., & Ramadori, G. P. (1997) · Acta Diabetologica · doi:10.1007/s005920050059 · Cited by 106 · see citing works

Enteroendocrine secretion of gut hormones in diabetes, obesity and after bariatric surgery

Holst, J. J. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.09.014 · Cited by 106 · see citing works

Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36

Iepsen, E. W., Lundgren, J., Holst, J. J., Madsbad, S., & Torekov, S. S. (2016) · European Journal of Endocrinology · doi:10.1530/eje-15-1116 · Cited by 101 · see citing works

PPG neurons of the lower brain stem and their role in brain GLP-1 receptor activation

Trapp, S., & Cork, S. C. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00333.2015 · Cited by 100 · see citing works

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells

Hodge, D., Glass, L. L., Diakogiannaki, E., Pais, R., Lenaghan, C., Smith, D. M., Wedin, M., Bohlooly-Y, M., Gribble, F. M., & Reimann, F. (2016) · Peptides · doi:10.1016/j.peptides.2015.06.012 · Cited by 99 · see citing works

Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine

Christensen, L. W., Kuhre, R. E., Janus, C., Svendsen, B., & Holst, J. J. (2015) · Physiological Reports · doi:10.14814/phy2.12551 · Cited by 99 · see citing works

Minireview: Finding the Sweet Spot: Peripheral Versus Central Glucagon-Like Peptide 1 Action in Feeding and Glucose Homeostasis

Williams, D. L. (2009) · Endocrinology · doi:10.1210/en.2009-0220 · Cited by 98 · see citing works

Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells

Pais, R., Gribble, F. M., & Reimann, F. M. (2015) · Peptides · doi:10.1016/j.peptides.2015.07.019 · Cited by 94 · see citing works

Cyclic AMP triggers glucagon-like peptide-1 secretion from the GLUTag enteroendocrine cell line

Simpson, A. K., Ward, P. S., Wong, K. Y., Collord, G., Habib, A. M., Reimann, F. M., & Gribble, F. M. (2007) · Diabetologia · doi:10.1007/s00125-007-0750-9 · Cited by 88 · see citing works

Electrical activity‐triggered glucagon‐like peptide‐1 secretion from primary murine L‐cells

Rogers, G. J., Tolhurst, G., Ramzan, A., Habib, A. M., Parker, H. E., Gribble, F. M., & Reimann, F. M. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2010.198069 · Cited by 86 · see citing works

Potentiation of Glucose-stimulated Insulin Secretion by the GPR40–PLC–TRPC Pathway in Pancreatic β-Cells

Yamada, H., Yoshida, M., Ito, K., Dezaki, K., Yada, T., Ishikawa, S.-E., & Kakei, M. (2016) · Scientific Reports · doi:10.1038/srep25912 · Cited by 81 · see citing works

GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism

Lin, H. V., Efanov, A. M., Fang, X., Beavers, L. S., Wang, X., Wang, J., Valcarcel, I. C. G., & Ma, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157298 · Cited by 72 · see citing works

Characterization and functional role of voltage gated cation conductances in the glucagon‐like peptide‐1 secreting GLUTag cell line

Reimann, F. M., Maziarz, M., Flock, G. B., Habib, A. M., Drucker, D. J., & Gribble, F. M. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.076414 · Cited by 71 · see citing works

Signaling Mechanisms Underlying the Release of Glucagon-Like Peptide 1

Reimann, F. M., Ward, P. S., & Gribble, F. M. (2006) · Diabetes · doi:10.2337/db06-s010 · Cited by 67 · see citing works

Gut Hormone Pharmacology of a Novel GPR119 Agonist (GSK1292263), Metformin, and Sitagliptin in Type 2 Diabetes Mellitus: Results from Two Randomized Studies

Nunez, D. J., Bush, M., Collins, D. A., McMullen, S. L., Gillmor, D., Apseloff, G., Atiee, G. J., Corsino, L., Morrow, L., & Feldman, P. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092494 · Cited by 65 · see citing works

Relationship between molecular structures of sugars and their ability to stimulate the release of glucagon-like peptide-1 from canine ileal loops.

Shima, K., Suda, T., Nishimoto, K., & Yoshimoto, S. (1990) · European Journal of Endocrinology · doi:10.1530/acta.0.1230464 · Cited by 64 · see citing works

Expression of functional GABAA receptors in cholecystokinin‐secreting gut neuroendocrine murine STC‐1 cells

Glassmeier, G., Herzig, K., Höpfner, M., Lemmer, K., Jansen, A., & Scherübl, H. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.805bj.x · Cited by 52 · see citing works

Distinct Cellular Origins for Serotonin-Expressing and Enterochromaffin-like Cells in the Gastric Corpus

Li, H. J., Johnston, B., Aiello, D. A., Caffrey, D. R., Giel–Moloney, M., Rindi, G., & Leiter, A. B. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.11.048 · Cited by 46 · see citing works

Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells

Koyama, H., Iwakura, H., Dote, K., Bando, M., Hosoda, H., Ariyasu, H., Kusakabe, T., Son, C., Hosoda, K., Akamizu, T., et al. (2015) · Endocrinology · doi:10.1210/en.2015-1784 · Cited by 45 · see citing works

Gut Hormone Regulation and Secretion via FFA1 and FFA4

Gribble, F. M., Diakogiannaki, E., & Reimann, F. M. (2016) · Handbook of experimental pharmacology · doi:10.1007/164_2016_46 · Cited by 36 · see citing works

Regulation of food intake: The gastric X/A-like endocrine cell in the spotlight

Stengel, A., & Taché, Y. (2009) · Current Gastroenterology Reports · doi:10.1007/s11894-009-0069-4 · Cited by 30 · see citing works

Gastrointestinal hormonal responses on GPR119 activation in lean and diseased rodent models of type 2 diabetes

Patel, S., Mace, O. J., Tough, I. R., White, J. R., Cock, T., Berglund, U. W., Schindler, M., & Cox, H. M. (2014) · International Journal of Obesity · doi:10.1038/ijo.2014.10 · Cited by 22 · see citing works

Plasma levels of glucagon‐like peptide 1 and markers of obesity among young and healthy adults

van der Stouwe, J. G., Aeschbacher, S., Krisai, P., Schoen, T., Meyre, P. B., Todd, J., Estis, J., Risch, M., Risch, L., & Conen, D. (2015) · Clinical Endocrinology · doi:10.1111/cen.12789 · Cited by 15 · see citing works

Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 Secretion

Riz, M., & Pedersen, M. G. (2015) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1004600 · Cited by 11 · see citing works

Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping

Gehart, H., van Es, J. H., Hamer, K., Beumer, J., Kretzschmar, K., Dekkers, J. F., Rios, A., & Clevers, H. (2019) · Cell · doi:10.1016/j.cell.2018.12.029 · Cited by 346 · see citing works

Mitochondrial function — gatekeeper of intestinal epithelial cell homeostasis

Rath, E., Moschetta, A., & Haller, D. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0021-x · Cited by 306 · see citing works

Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution

Busslinger, G. A., Weusten, B. L. A. M., Bogte, A., Begthel, H., Brosens, L. A. A., & Clevers, H. C. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108819 · Cited by 276 · see citing works

Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease

Hegyi, P., Maléth, J., Walters, J. R., Hofmann, A. F., & Keely, S. J. (2018) · Physiological Reviews · doi:10.1152/physrev.00054.2017 · Cited by 269 · see citing works

A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics

Burclaff, J., Bliton, R. J., Breau, K. A., Ok, M. T., Gomez-Martinez, I., Ranek, J. S., Bhatt, A. P., Purvis, J. E., Woosley, J. T., & Magness, S. T. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.02.007 · Cited by 242 · see citing works

High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells

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GLP-1: Molecular mechanisms and outcomes of a complex signaling system

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