The intestine as an endocrine organ and the role of gut hormones in metabolic regulation

Identification of stem cells in small intestine and colon by marker gene Lgr5

Barker, N., van Es, J. H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J., et al. (2007) · Nature · doi:10.1038/nature06196 · Cited by 5,687 · see citing works

Gut hormone PYY3-36 physiologically inhibits food intake

Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., et al. (2002) · Nature · doi:10.1038/nature00887 · Cited by 2,351 · see citing works

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

Armstrong, M. J., Gaunt, P., Aithal, G. P., Barton, D., Hull, D., Parker, R., Hazlehurst, J. M., Guo, K., Abouda, G., Aldersley, M. A., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00803-x · Cited by 2,203 · see citing works

A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

Howard, A., Feighner, S., Cully, D., Arena, J. P., Liberator, P., Rosenblum, C., Hamelin, M., Hreniuk, D. L., Palyha, O., Anderson, J., et al. (1996) · Science · doi:10.1126/science.273.5277.974 · Cited by 2,106 · see citing works

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes

Frías, J. P., Davies, M. J., Rosenstock, J., Pérez Manghi, F. C., Fernández Landó, L., Bergman, B. K., Liu, B., Cui, X., & Brown, K. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2107519 · Cited by 2,096 · cited 1× · see citing works

Glucagon-like peptide 1 (GLP-1)

Müller, T. D., Finan, B., Bloom, S. R., D'Alessio, D., Drucker, D. J., Flatt, P. R., Fritsche, A., Gribble, F., Grill, H. J., Habener, J. F., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.09.010 · Cited by 1,868 · see citing works

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

Cowley, M. A., Smith, R. G., Diano, S., Tschöp, M., Pronchuk, N., Grove, K. L., Strasburger, C. J., Bidlingmaier, M., Esterman, M., Heiman, M. L., et al. (2003) · Neuron · doi:10.1016/s0896-6273(03)00063-1 · Cited by 1,679 · see citing works

Cholecystokinin decreases food intake in rats.

Gibbs, J., Young, R. C., & Smith, G. P. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0034870 · Cited by 1,498 · see citing works

Characteristics of the Cholecystokinin-Induced Depolarization of Pacemaking Activity in Cultured Interstitial Cells of Cajal from Murine Small Intestine

Lee, J. H., Kim, S.-Y., Kwon, Y. K., Kim, B. J., & So, I. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350075 · Cited by 1,380 · see citing works

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

Date, Y., Murakami, N., Toshinai, K., Matsukura, S., Niijima, A., Matsuo, H., Kangawa, K., & Nakazato, M. (2002) · Gastroenterology · doi:10.1053/gast.2002.35954 · Cited by 1,081 · see citing works

The Discovery and Development of Liraglutide and Semaglutide

Knudsen, L. B., & Lau, J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00155 · Cited by 970 · see citing works

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

Miyawaki, K., Yamada, Y., Ban, N., Ihara, Y., Tsukiyama, K., Zhou, H., Fujimoto, S., Oku, A., Tsuda, K., Toyokuni, S., et al. (2002) · Nature Medicine · doi:10.1038/nm727 · Cited by 963 · see citing works

A gut-brain neural circuit for nutrient sensory transduction

Kaelberer, M. M., Buchanan, K. L., Klein, M. E., Barth, B. B., Montoya, M. M., Shen, X., & Bohórquez, D. V. (2018) · Science · doi:10.1126/science.aat5236 · Cited by 932 · see citing works

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

Coskun, T., Sloop, K. W., Loghin, C., Alsina-Fernandez, J., Urva, S., Bokvist, K. B., Cui, X., Briere, D. A., Cabrera, O., Roell, W. C., et al. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.09.009 · Cited by 882 · see citing works

Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients

Toft-Nielsen, M.-B., Damholt, M. B., Madsbad, S., Hilsted, L. M., Hughes, T. E., Michelsen, B. K., & Holst, J. J. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.8.7750 · Cited by 869 · see citing works

The role of incretins in glucose homeostasis and diabetes treatment

Kim, W., & Egan, J. M. (2008) · Pharmacological Reviews · doi:10.1124/pr.108.000604 · Cited by 824 · see citing works

Glucose Sensing in L Cells: A Primary Cell Study

Reimann, F., Habib, A. M., Tolhurst, G., Parker, H. E., Rogers, G. J., & Gribble, F. M. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.11.002 · Cited by 733 · cited 1× · see citing works

Na+-<scp>d</scp>-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

Gorboulev, V., Schürmann, A., Vallon, V., Kipp, H., Jaschke, A., Klessen, D., Friedrich, A., Scherneck, S., Rieg, T., Cunard, R., et al. (2012) · Diabetes · doi:10.2337/db11-1029 · Cited by 687 · see citing works

Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium

Gribble, F. M., & Reimann, F. (2016) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105439 · Cited by 683 · see citing works

Function and mechanisms of enteroendocrine cells and gut hormones in metabolism

Gribble, F. M., & Reimann, F. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0168-8 · Cited by 670 · see citing works

Sensory neurons that detect stretch and nutrients in the digestive system

Williams, E. K., Chang, R. B., Strochlic, D. E., Umans, B. D., Lowell, B. B., & Liberles, S. D. (2016) · Cell · doi:10.1016/j.cell.2016.05.011 · Cited by 645 · see citing works

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial.

Ludvik, B., Giorgino, F., Jódar, E., Frias, J. P., Fernández Landó, L., Brown, K., Bray, R., & Rodríguez, Á. (2021) · The Lancet · doi:10.1016/s0140-6736(21)01443-4 · Cited by 639 · see citing works

Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes

Dahl, D., Onishi, Y., Norwood, P., Huh, R., Bray, R., Patel, H., & Rodríguez, Á. (2022) · JAMA · doi:10.1001/jama.2022.0078 · Cited by 597 · see citing works

The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion

MacDonald, P. E., El-kholy, W., Riedel, M. J., Salapatek, A. M. F., Light, P. E., & Wheeler, M. B. (2002) · Diabetes · doi:10.2337/diabetes.51.2007.s434 · Cited by 590 · see citing works

GDF15 mediates the effects of metformin on body weight and energy balance

Coll, A. P., Chen, M., Taskar, P., Rimmington, D., Patel, S., Tadross, J. A., Cimino, I., Yang, M., Welsh, P., Virtue, S., et al. (2020) · Nature · doi:10.1038/s41586-019-1911-y · Cited by 584 · see citing works

Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice

Ding, X., Saxena, N. K., Lin, S., Gupta, N., & Anania, F. A. (2006) · Hepatology · doi:10.1002/hep.21006 · Cited by 557 · see citing works

Glucagon-Like Peptide-1 Receptor Is Present on Human Hepatocytes and Has A Direct Role in Decreasing Hepatic Steatosis in Vitro by Modulating Elements of the Insulin Signaling Pathway

Gupta, N. A., Mells, J., Dunham, R. M., Grakoui, A., Handy, J., Saxena, N. K., & Anania, F. A. (2010) · Hepatology · doi:10.1002/hep.23569 · Cited by 532 · see citing works

Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients

T., V., T., K., S., M., & J., H. (2002) · Diabetologia · doi:10.1007/s00125-002-0878-6 · Cited by 518 · see citing works

Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

Gastaldelli, A., Cusi, K., Fernández Landó, L., Bray, R., Brouwers, B., & Rodríguez, Á. (2022) · The Lancet Diabetes &amp; Endocrinology · doi:10.1016/s2213-8587(22)00070-5 · Cited by 513 · see citing works

Expression cloning and characterization of the canine parietal cell gastrin receptor.

Kopin, A. S., Lee, Y. M., McBride, E. W., Miller, L. J., Lu, M., Lin, H. Y.-F., Kolakowski, L. F., & Beinborn, M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.8.3605 · Cited by 507 · see citing works

Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations

Nauck, M. A., Bartels, E., Ørskov, C., Ebert, R., & Creutzfeldt, W. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.4.8473405 · Cited by 505 · see citing works

Identification and characterization of GLP-1 receptor–expressing cells using a new transgenic mouse model

Richards, P., Parker, H. E., Adriaenssens, A. E., Hodgson, J. M., Cork, S. C., Trapp, S., Gribble, F. M., & Reimann, F. (2014) · Diabetes · doi:10.2337/db13-1440 · Cited by 472 · see citing works

GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects

Zhao, X., Wang, M., Wen, Z., Lu, Z., Cui, L., Fu, C., Xue, H., Liu, Y., & Zhang, Y. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.721135 · Cited by 463 · see citing works

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Crane, J., Palanivel, R., Mottillo, E., Bujak, A. L., Wang, H.-Q., Ford, R., Collins, A., Blümer, R., Fullerton, M., Yabut, J. M., et al. (2014) · Nature Medicine · doi:10.1038/nm.3766 · Cited by 462 · see citing works

Glucagon-Like Peptide-1 Induces Cell Proliferation and Pancreatic-Duodenum Homeobox-1 Expression and Increases Endocrine Cell Mass in the Pancreas of Old, Glucose-Intolerant Rats

Perfetti, R., Zhou, J., Doyle, M. E., & Egan, J. M. (2000) · Endocrinology · doi:10.1210/endo.141.12.7806 · Cited by 442 · see citing works

Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

Vilsbøll, T., Krarup, T., Madsbad, S., & Holst, J. J. (2003) · Regulatory Peptides · doi:10.1016/s0167-0115(03)00111-3 · Cited by 430 · see citing works

Bile Acids as Hormones: The FXR-FGF15/19 Pathway

Kliewer, S. A., & Mangelsdorf, D. J. (2015) · Digestive Diseases · doi:10.1159/000371670 · Cited by 424 · see citing works

How May GIP Enhance the Therapeutic Efficacy of GLP-1?

Samms, R. J., Coghlan, M. P., & Sloop, K. W. (2020) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2020.02.006 · Cited by 419 · see citing works

Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

Højberg, P. V., Vilsbøll, T., Rabøl, R., Knop, F. K., Bache, M., Krarup, T., Holst, J. J., & Madsbad, S. (2009) · Diabetologia · doi:10.1007/s00125-008-1195-5 · Cited by 414 · see citing works

Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction

Nauck, M. A., & D‘Alessio, D. A. (2022) · Cardiovascular Diabetology · doi:10.1186/s12933-022-01604-7 · Cited by 407 · see citing works

Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis

Svegliati‐Baroni, G., Saccomanno, S., Rychlicki, C., Agostinelli, L., De Minicis, S., Candelaresi, C., Faraci, G., Pacetti, D., Vivarelli, M., Nicolini, D., et al. (2011) · Liver International · doi:10.1111/j.1478-3231.2011.02462.x · Cited by 405 · see citing works

Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons

Li, Z., Chalazonitis, A., Huang, Y.-Y., Mann, J. J., Margolis, K. G., Yang, Q. M., Kim, D. O., Cote, F., Mallet, J., & Gershon, M. D. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6684-10.2011 · Cited by 403 · see citing works

The evolving story of incretins ( <scp>GIP</scp> and <scp>GLP</scp> ‐1) in metabolic and cardiovascular disease: A pathophysiological update

Nauck, M. A., Quast, D. R., Wefers, J., & Pfeiffer, A. F. H. (2021) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.14496 · Cited by 388 · see citing works

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

Habib, A. M., Richards, P., Cairns, L. S., Rogers, G. J., Bannon, C. A. M., Parker, H. E., Morley, T. C. E., Yeo, G. S. H., Reimann, F. M., & Gribble, F. M. (2012) · Endocrinology · doi:10.1210/en.2011-2170 · Cited by 382 · see citing works

Enteroendocrine cells: a site of 'taste' in gastrointestinal chemosensing

Sternini, C., Anselmi, L., & Rozengurt, E. (2008) · Current Opinion in Endocrinology, Diabetes &amp; Obesity · doi:10.1097/med.0b013e3282f43a73 · Cited by 377 · see citing works

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure

Baggio, L. L., Huang, Q., Brown, T. J., & Drucker, D. J. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.04.063 · Cited by 372 · see citing works

Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial

Wynne, K., Park, A. J., Small, C. J., Meeran, K., Ghatei, M. A., Frost, G. S., & Bloom, S. R. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803344 · Cited by 363 · see citing works

Molecular Physiology of Membrane Guanylyl Cyclase Receptors

Kühn, M. (2016) · Physiological Reviews · doi:10.1152/physrev.00022.2015 · Cited by 358 · see citing works

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

Brighton, C. A., Rievaj, J., Kuhre, R. E., Glasssmith, L. L., Schoonjans, K., Holst, J. J., Gribble, F. M., & Reimann, F. M. (2015) · Endocrinology · doi:10.1210/en.2015-1321 · Cited by 355 · see citing works

Reduced Incretin Effect in Type 2 Diabetes

Knop, F. K., Vilsbøll, T., Højberg, P. V., Larsen, S., Madsbad, S., Vølund, A., Holst, J. J., & Krarup, T. (2007) · Diabetes · doi:10.2337/db07-0100 · Cited by 349 · see citing works

Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4

Kanoski, S. E., Fortin, S. M., Arnold, M., Grill, H. J., & Hayes, M. R. (2011) · Endocrinology · doi:10.1210/en.2011-0174 · Cited by 347 · see citing works

Gastrointestinal satiety signals II. Cholecystokinin

Moran, T. H., & Kinzig, K. P. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00434.2003 · Cited by 346 · see citing works

GLP-1 Receptor Activation Indirectly Reduces Hepatic Lipid Accumulation But Does Not Attenuate Development of Atherosclerosis in Diabetic Male ApoE−/− Mice

Panjwani, N., Mulvihill, E. E., Longuet, C., Yusta, B., Campbell, J. E., Brown, T. J., Streutker, C., Holland, D., Cao, X., Baggio, L. L., et al. (2013) · Endocrinology · doi:10.1210/en.2012-1937 · Cited by 346 · see citing works

Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance

Jørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, D., Lindqvist Hansen, D., et al. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00073.2012 · Cited by 313 · see citing works

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, J. J., Schuit, F., & Drucker, D. J. (2004) · Diabetes · doi:10.2337/diabetes.53.5.1326 · Cited by 309 · see citing works

The Physiology of the Gastric Parietal Cell

Engevik, A. C., Kaji, I., & Goldenring, J. R. (2019) · Physiological Reviews · doi:10.1152/physrev.00016.2019 · Cited by 305 · see citing works

Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor Activation

McLean, B. A., Wong, C. K., Campbell, J. E., Hodson, D. J., Trapp, S., & Drucker, D. J. (2021) · Endocrine Reviews · doi:10.1210/endrev/bnaa032 · Cited by 289 · see citing works

Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient

Beumer, J., Artegiani, B., Post, Y., Reimann, F. M., Gribble, F. M., Nguyen, T. N., Zeng, H., van den Born, M., van Es, J. H., & Clevers, H. C. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0143-y · Cited by 280 · see citing works

Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes

Holst, J. J., Knop, F. K., Vilsbøll, T., Krarup, T., & Madsbad, S. (2011) · Diabetes Care · doi:10.2337/dc11-s227 · Cited by 280 · see citing works

Therapeutic pipeline in nonalcoholic steatohepatitis

Vuppalanchi, R., Noureddin, M., Alkhouri, N., & Sanyal, A. J. (2021) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-020-00408-y · Cited by 278 · see citing works

Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice

Trevaskis, J. L., Griffin, P. S., Wittmer, C., Neuschwander-Tetri, B. A., Brunt, E. M., Dolman, C. S., Erickson, M. R., Napora, J., Parkes, D. G., & Roth, J. D. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00476.2011 · Cited by 277 · see citing works

The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

Hare, K. J., Vilsbøll, T., Asmar, M., Deacon, C. F., Knop, F. K., & Holst, J. J. (2010) · Diabetes · doi:10.2337/db09-1414 · Cited by 276 · see citing works

Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells.

Wang, T. C., Bonner-Weir, S., Oates, P. S., Chulak, M., Simon, B., Merlino, G. T., Schmidt, E. V., & Brand, S. J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116708 · Cited by 270 · see citing works

Area postrema cell types that mediate nausea-associated behaviors

Zhang, C., Kaye, J. A., Cai, Z., Wang, Y., Prescott, S. L., & Liberles, S. D. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.010 · Cited by 263 · see citing works

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

De Marinis, Y. Z., Salehi, A., Ward, C. E., Zhang, Q., Abdulkader, F., Bengtsson, M., Braha, O., Braun, M., Ramracheya, R., Amisten, S., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.04.007 · Cited by 257 · see citing works

GDF15: a hormone conveying somatic distress to the brain

Lockhart, S. M., Saudek, V., & O’Rahilly, S. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa007 · Cited by 256 · see citing works

GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice

Samms, R. J., Christe, M. E., Collins, K. A. L., Pirro, V., Droz, B. A., Holland, A. K., Friedrich, J. L., Wojnicki, S., Konkol, D. L., Cosgrove, R., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci146353 · Cited by 256 · see citing works

The incretin system in healthy humans: The role of GIP and GLP-1

Holst, J. J. (2019) · Metabolism · doi:10.1016/j.metabol.2019.04.014 · Cited by 248 · see citing works

Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1

Hammoud, R., & Drucker, D. J. (2023) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00783-3 · Cited by 244 · see citing works

Role of prohormone convertases in the tissue-specific processing of proglucagon

Dhanvantari, S., Seidah, N. G., & BRUBAKER, P. L. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.4.8721980 · Cited by 242 · see citing works

Gut chemosensing mechanisms

Psichas, A., Reimann, F. M., & Gribble, F. M. (2015) · Journal of Clinical Investigation · doi:10.1172/jci76309 · Cited by 240 · see citing works

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

de Heer, J., Rasmussen, C. E., Coy, D. H., & Holst, J. J. (2008) · Diabetologia · doi:10.1007/s00125-008-1149-y · Cited by 238 · see citing works

GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

McClean, P. L., Irwin, N., Cassidy, R. S., Holst, J. J., Gault, V. A., & Flatt, P. R. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00460.2007 · Cited by 237 · see citing works

G-Protein-Coupled Receptors in Intestinal Chemosensation

Reimann, F. M., Tolhurst, G., & Gribble, F. M. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2011.12.019 · Cited by 235 · see citing works

Gut Vagal Afferents Are Not Necessary for the Eating-Stimulatory Effect of Intraperitoneally Injected Ghrelin in the Rat

Arnold, M., Mura, A., Langhans, W., & Geary, N. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2606-06.2006 · Cited by 233 · see citing works

The Pathophysiology of Diabetes Involves a Defective Amplification of the Late-Phase Insulin Response to Glucose by Glucose-Dependent Insulinotropic Polypeptide—Regardless of Etiology and Phenotype

Vilsbøll, T., Knop, F. K., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T. W., Pedersen, O. B., & Holst, J. J. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030738 · Cited by 230 · see citing works

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation

Li, Y., Schnabl, K., Gabler, S.-M., Willershäuser, M., Reber, J., Karlas, A., Laurila, S., Lahesmaa, M., u Din, M., Bast-Habersbrunner, A., et al. (2018) · Cell · doi:10.1016/j.cell.2018.10.016 · Cited by 228 · see citing works

High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells

Beumer, J., Puschhof, J., Bauzá‐Martinez, J., Martínez-Silgado, A., Elmentaite, R., James, K. R., Ross, A., Hendriks, D. F. G., Artegiani, B., Busslinger, G. A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.04.036 · Cited by 224 · see citing works

The physiology of gastric emptying

Hellström, P. M., Grybäck, P., & Jacobsson, H. (2006) · Best Practice &amp; Research Clinical Anaesthesiology · doi:10.1016/j.bpa.2006.02.002 · Cited by 223 · see citing works

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, J. J., Reimann, F., & Gribble, F. M. (2016) · Diabetologia · doi:10.1007/s00125-016-4033-1 · Cited by 223 · see citing works

GIP as a Therapeutic Target in Diabetes and Obesity: Insight From Incretin Co-agonists

Holst, J. J., & Rosenkilde, M. M. (2020) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/clinem/dgaa327 · Cited by 207 · see citing works

The role of neurotensin in central nervous system pathophysiology: What is the evidence?

St-Gelais, F., Jomphe, C., & Trudeau, L. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0627 · Cited by 206 · see citing works

Peptide YY(1-36) and Peptide YY(3-36): Part I. Distribution, Release and Actions

Ballantyne, G. H. (2006) · Obesity Surgery · doi:10.1381/096089206776944959 · Cited by 205 · see citing works

LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial

Urva, S., Coskun, T., Loh, M. T., Du, Y., Thomas, M. K., Gurbuz, S., Haupt, A., Benson, C. T., Hernandez-Illas, M., D’Alessio, D. A., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(22)02033-5 · Cited by 202 · see citing works

The Extrapancreatic Effects of Glucagon-Like Peptide-1 and Related Peptides

Abu‐Hamdah, R., Rabiee, A., Meneilly, G. S., Shannon, R. P., Andersen, D. K., & Elahi, D. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1296 · Cited by 202 · see citing works

GIP receptor agonism attenuates GLP-1 receptor agonist induced nausea and emesis in preclinical models

Borner, T., Geisler, C. E., Fortin, S. M., Cosgrove, R., Alsina-Fernandez, J., Dogra, M., Doebley, S., Sanchez-Navarro, M. J., Leon, R. M., Gaisinsky, J., et al. (2021) · Diabetes · doi:10.2337/db21-0459 · Cited by 202 · see citing works

Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor

Diakogiannaki, E., Pais, R., Tolhurst, G., Parker, H. E., Horscroft, J. A., Rauscher, B., Zietek, T., Daniel, H., Gribble, F. M., & Reimann, F. M. (2013) · Diabetologia · doi:10.1007/s00125-013-3037-3 · Cited by 200 · see citing works

Suppression of glucose production by GLP-1 independent of islet hormones: A novel extrapancreatic effect

Prigeon, R. L., Quddusi, S., Paty, B., & D'Alessio, D. A. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00024.2003 · Cited by 199 · see citing works

The regulation of food intake by the gut-brain axis: implications for obesity

Hussain, S., & Bloom, S. R. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.93 · Cited by 195 · see citing works

Action and therapeutic potential of oxyntomodulin

Pocai, A. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2013.12.001 · Cited by 191 · see citing works

Effect of the entero-pancreatic hormones, gastric inhibitory polypeptide and glucagon-like polypeptide-1(7–36) amide, on fatty acid synthesis in explants of rat adipose tissue

Oben, J. E., Morgan, L. D., Fletcher, J. M., & Marks, V. (1991) · Journal of Endocrinology · doi:10.1677/joe.0.1300267 · Cited by 189 · see citing works

Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Wewer Albrechtsen, N. J., Rehfeld, J. F., Hartmann, B., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.121 · Cited by 185 · see citing works

Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans

Asmar, M., Simonsen, L., Madsbad, S., Stallknecht, B., Holst, J. J., & Bülow, J. (2010) · Diabetes · doi:10.2337/db10-0098 · Cited by 184 · see citing works

Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes

Gautier, J. F., Choukem, S. P., & Girard, J. R. (2008) · Diabetes & Metabolism · doi:10.1016/s1262-3636(08)73397-4 · Cited by 181 · see citing works

Glucagon-like Peptide-1 Receptor-based Therapeutics for Metabolic Liver Disease

Yabut, J. M., & Drucker, D. J. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnac018 · Cited by 180 · see citing works

Reappraisal of GIP Pharmacology for Metabolic Diseases

Finan, B., Müller, T. D., Clemmensen, C., Perez-Tilve, D., DiMarchi, R. D., & Tschöp, M. H. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.03.005 · Cited by 180 · see citing works

Gut–brain circuits for fat preference

Li, M.-T., Tan, H.-E., Lu, Z., Tsang, K. S., Chung, A. J., & Zuker, C. S. (2022) · Nature · doi:10.1038/s41586-022-05266-z · Cited by 170 · see citing works

The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

Lund, A., Vilsbøll, T., Bagger, J. I., Holst, J. J., & Knop, F. K. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00665.2010 · Cited by 169 · see citing works

Gut enterochromaffin cells drive visceral pain and anxiety

Bayrer, J. R., Castro, J., Venkataraman, A., Touhara, K. K., Rossen, N. D., Morrie, R. D., Maddern, J., Hendry, A., Braverman, K. N., Garcia‐Caraballo, S., et al. (2023) · Nature · doi:10.1038/s41586-023-05829-8 · Cited by 163 · see citing works

The Emerging Role of Glucagon-like Peptide-1 Receptor Agonists for the Management of NAFLD

Chavez, C. P., Cusi, K. J., & Kadiyala, S. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab578 · Cited by 163 · see citing works

The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

Shimoda, M., Kanda, Y., Hamamoto, S., Tawaramoto, K., Hashiramoto, M., Matsuki, M., & Kaku, K. (2011) · Diabetologia · doi:10.1007/s00125-011-2069-9 · Cited by 161 · see citing works

GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation

Mayendraraj, A., ROSENKILDE, M. M., & Gasbjerg, L. S. (2022) · Peptides · doi:10.1016/j.peptides.2022.170749 · Cited by 158 · see citing works

Stimulation of pancreatic β-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways

Friedrichsen, B. N., Neubauer, N., Lee, Y. C., Gram, V. K., Blume, N., Petersen, J. S., Nielsen, J. H., & Møldrup, A. (2006) · Journal of Endocrinology · doi:10.1677/joe.1.06160 · Cited by 147 · see citing works

Regulation of glucagon secretion by incretins

Holst, J. J., Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. L., & Knop, F. K. (2011) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2011.01452.x · Cited by 143 · see citing works

Direct effect of GLP-1 infusion on endogenous glucose production in humans

Seghieri, M., Rebelos, E., Gastaldelli, A., Astiarraga, B. D., Casolaro, A., Barsotti, E., Pocai, A., Nauck, M., Muscelli, E., & Ferrannini, E. (2013) · Diabetologia · doi:10.1007/s00125-012-2738-3 · Cited by 143 · see citing works

Targeted inactivation of the neurotensin type 1 receptor reveals its role in body temperature control and feeding behavior but not in analgesia

Rémaury, A., Vita, N., Gendreau, S., Jung, M., Arnone, M., Poncelet, M., Culouscou, J., Fur, G. L., Soubrié, P., Caput, D., et al. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03271-7 · Cited by 141 · see citing works

Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice

Song, Y., Koehler, J. A., Baggio, L. L., Powers, A. C., Sandoval, D. A., & Drucker, D. J. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.08.009 · Cited by 140 · see citing works

Insulin-like peptide 5 is an orexigenic gastrointestinal hormone

Grosse, J., Heffron, H., Burling, K., Hossain, M. A., Habib, A. M., Rogers, G. J., Richards, P., Larder, R., Rimmington, D., Adriaenssens, A. E., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411413111 · Cited by 139 · see citing works

The Role of Incretins on Insulin Function and Glucose Homeostasis

Holst, J. J., Gasbjerg, L. S., & ROSENKILDE, M. M. (2021) · Endocrinology · doi:10.1210/endocr/bqab065 · Cited by 134 · see citing works

Targeting the GIPR for obesity: To agonize or antagonize? Potential mechanisms

Campbell, J. E. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101139 · Cited by 133 · see citing works

The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor

Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, L. S., Sparre-Ulrich, A. H., Rosenkilde, M. M., Hartmann, B., Dela, F., Holst, J. J., & Bülow, J. (2017) · Diabetes · doi:10.2337/db17-0480 · Cited by 132 · see citing works

Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat

Piteau, S., Olver, A., Kim, S.-J., Winter, K., Pospisilik, J. A., Lynn, F., Manhart, S., Demuth, H.-U., Speck, M., Pederson, R. A., et al. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.08.115 · Cited by 130 · see citing works

Effects of cholecystokinin-octapeptide (CCK-8) on food intake and gastric emptying in man

Muurahainen, N., Kissileff, H. R., Derogatis, A. J., & Pi-Sunyer, X. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90330-7 · Cited by 130 · see citing works

Ghrelin and motilin receptors as drug targets for gastrointestinal disorders

Sanger, G. J., & Furness, J. B. (2015) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.163 · Cited by 128 · see citing works

GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca ²⁺ channels

Ramracheya, R., Chapman, C., Chibalina, M., Dou, H., Miranda, C., González, A., Moritoh, Y., Shigeto, M., Zhang, Q., Braun, M., et al. (2018) · Physiological Reports · doi:10.14814/phy2.13852 · Cited by 128 · see citing works

Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets

Gault, V. A., McClean, P. L., Cassidy, R. S., Irwin, N., & Flatt, P. R. (2007) · Diabetologia · doi:10.1007/s00125-007-0710-4 · Cited by 127 · see citing works

Two‐year effect of semaglutide 2.4 mg on control of eating in adults with overweight/obesity: <scp>STEP</scp> 5

Wharton, S., Batterham, R. L., Bhatta, M., Buscemi, S., Christensen, L. N., Frias, J. P., Jódar, E., Kandler, K., Rigas, G., Wadden, T. A., et al. (2023) · Obesity · doi:10.1002/oby.23673 · Cited by 124 · see citing works

Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity

Hamra, F. K., Eber, S. L., Chin, D. T., Currie, M. G., & Forte, L. R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.6.2705 · Cited by 121 · see citing works

Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists

Gasbjerg, L. S., Bergmann, N. C., Stensen, S., Christensen, M. B., Rosenkilde, M. M., Holst, J. J., Nauck, M., & Knop, F. K. (2020) · Peptides · doi:10.1016/j.peptides.2019.170183 · Cited by 121 · see citing works

The Interplay of Glucagon-Like Peptide-1 Receptor Trafficking and Signalling in Pancreatic Beta Cells

Marzook, A., Tomas, A., & Jones, B. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.678055 · Cited by 121 · see citing works

GLP-1 and GLP-2 Orchestrate Intestine Integrity, Gut Microbiota, and Immune System Crosstalk

Abdalqadir, N., & Adeli, K. (2022) · Microorganisms · doi:10.3390/microorganisms10102061 · Cited by 119 · see citing works

Antagonism of Rat β-Cell Voltage-dependent K+ Currents by Exendin 4 Requires Dual Activation of the cAMP/Protein Kinase A and Phosphatidylinositol 3-Kinase Signaling Pathways

MacDonald, P. E., Wang, X., Xia, F., El-kholy, W., Targonsky, E. D., Tsushima, R. G., & Wheeler, M. B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307612200 · Cited by 117 · see citing works

Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity

Opland, D. M., Sutton, A. K., Woodworth, H. L., Brown, J. A., Bugescu, R., Garcia, A. V. C.-G., Christensen, L., Rhodes, C. J., Myers, M. G., & Leinninger, G. M. (2013) · Molecular Metabolism · doi:10.1016/j.molmet.2013.07.008 · Cited by 116 · see citing works

Glucagon‐like peptide‐1 reduces hepatic glucose production indirectly through insulin and glucagon in humans

Larsson, H. E., Holst, J. J., & Åhrén, B. (1997) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1997.00161.x · Cited by 115 · see citing works

Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids

Zhang, J. H., Nolan, J., Kennie, S. L., Johnston, I. M., Dew, T. K., Dixon, P. H., Williamson, C., & Walters, J. R. F. (2013) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00398.2012 · Cited by 114 · see citing works

Endogenous ghrelin is an orexigenic peptide acting in the arcuate nucleus in response to fasting

Bagnasco, M., Tulipano, G., Melis, M. R., Argiolas, A., Cocchi, D., & Müller, E. E. (2003) · Regulatory Peptides · doi:10.1016/s0167-0115(02)00283-5 · Cited by 113 · see citing works

Gut???brain axis

Romijn, J. A., Corssmit, E. P. M., Havekes, L. M., & Pijl, H. (2008) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328302c9b0 · Cited by 112 · see citing works

Disruption of GIP/GIPR axis in human adipose tissue is linked to obesity and insulin resistance

Ceperuelo-Mallafré, V., Duran, X., Pachón, G., Roche, K., Garrido-Sánchez, L., Vilarrasa, N., Tinahones, F. J., Vicente, V., Pujol, J., Vendrell, J., et al. (2014) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2013-3350 · Cited by 112 · see citing works

Mechanisms controlling hormone secretion in human gut and its relevance to metabolism

Martin, A. M., Sun, E. W. L., & Keating, D. J. (2019) · Journal of Endocrinology · doi:10.1530/joe-19-0399 · Cited by 110 · see citing works

Gut motility and enteroendocrine secretion

Wu, T., Rayner, C. K., Young, R. L., & Horowitz, M. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.09.002 · Cited by 110 · see citing works

The Multifaceted Role of Serotonin in Intestinal Homeostasis

Koopman, N., Katsavelis, D., ten Hove, A. S., Brul, S., de Jonge, W. J., & Seppen, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179487 · Cited by 107 · see citing works

Prolonged saturated fat–induced, glucose-dependent insulinotropic polypeptide elevation is associated with adipokine imbalance and liver injury in nonalcoholic steatohepatitis: dysregulated enteroadipocyte axis as a novel feature of fatty liver

Musso, G., Gambino, R., Pacini, G., De Michieli, F., & Cassader, M. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26720 · Cited by 107 · see citing works

The Brain-Gut Axis in Health and Disease

Omran, Y. A., & Aziz, Q. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-0897-4_6 · Cited by 106 · see citing works

The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice

Orgaard, A., & Holst, J. (2017) · Diabetologia · doi:10.1007/s00125-017-4315-2 · Cited by 102 · see citing works

GLP‐1 (9–36) Amide, Cleavage Product of GLP‐1 (7–36) Amide, Is a Glucoregulatory Peptide

Elahi, D., Egan, J. M., Shannon, R. P., Meneilly, G. S., Khatri, A., Habener, J. F., & Andersen, D. K. (2008) · Obesity · doi:10.1038/oby.2008.229 · Cited by 101 · see citing works

GLP-1-derived nonapeptide GLP-1(28–36)amide targets to mitochondria and suppresses glucose production and oxidative stress in isolated mouse hepatocytes

Tomás, E., Stanojevic, V., & Habener, J. F. (2011) · Regulatory Peptides · doi:10.1016/j.regpep.2011.01.003 · Cited by 100 · see citing works

The Effect of Glucagon-Like Peptide I (GLP-I) on Glucose Elimination in Healthy Subjects Depends on the Pancreatic Glucoregulatory Hormones

Toft-Nielson, M.-B., Madsbad, S., & Holst, J. J. (1996) · Diabetes · doi:10.2337/diab.45.5.552 · Cited by 99 · see citing works

Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine

Christensen, L. W., Kuhre, R. E., Janus, C., Svendsen, B., & Holst, J. J. (2015) · Physiological Reports · doi:10.14814/phy2.12551 · Cited by 99 · see citing works

β-Adrenergic Receptors and Adipose Tissue Metabolism: Evolution of an Old Story

Collins, S. (2022) · Annual Review of Physiology · doi:10.1146/annurev-physiol-060721-092939 · Cited by 98 · see citing works

Peptide YY: more than just an appetite regulator

Persaud, S. J., & Bewick, G. A. (2014) · Diabetologia · doi:10.1007/s00125-014-3292-y · Cited by 97 · see citing works

The role of GIP in α-cells and glucagon secretion

EL, K. M., & Campbell, J. E. (2019) · Peptides · doi:10.1016/j.peptides.2019.170213 · Cited by 97 · see citing works

Lipids, CHOs, proteins: Can all macronutrients put a ‘brake’ on eating?

Shin, H.-S., Ingram, J. R., McGill, A., & Poppitt, S. D. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.07.008 · Cited by 97 · see citing works

Leptin receptor–expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice

Cheng, W., Ndoka, E., Hutch, C. R., Roelofs, K. J., MacKinnon, A., Khoury, B. M., Magrisso, I. J., Kim, K. S., Rhodes, C. J., Olson, D. P., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.134359 · Cited by 97 · see citing works

Exenatide improves both hepatic and adipose tissue insulin resistance: A dynamic positron emission tomography study

Gastaldelli, A., Gaggini, M., Daniele, G., Ciociaro, D., Cersosimo, E., Tripathy, D., Triplitt, C., Fox, P., Musi, N., DeFronzo, R., et al. (2016) · Hepatology · doi:10.1002/hep.28827 · Cited by 96 · see citing works

Control of insulin secretion by GLP-1

Jones, B. J., Bloom, S. R., Buenaventura, T., Tomás, A., & Rutter, G. A. (2018) · Peptides · doi:10.1016/j.peptides.2017.12.013 · Cited by 96 · see citing works

Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue

Samms, R. J., Zhang, G., He, W., Ilkayeva, O., Droz, B. A., Bauer, S. M., Stutsman, C., Pirro, V., Collins, K. A., Furber, E. C., et al. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101550 · Cited by 93 · see citing works

Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD

Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, F. K., & Vilsbøll, T. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00649 · Cited by 92 · see citing works

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

Taher, J., Baker, C. L., Cuizon, C., Masoudpour, H., Zhang, R., Farr, S., Naples, M., Bourdon, C., Pausová, Z., & Adeli, K. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.09.005 · Cited by 91 · see citing works

A novel pathway for regulation of glucose‐dependent insulinotropic polypeptide receptor expression in β‐cells

Lynn, F. C., Thompson, S. A., Pospisilik, J. A., Ehses, J. A., Hinke, S. A., Pamir, N., McIntosh, C. H. S., & Pederson, R. A. (2003) · The FASEB Journal · doi:10.1096/fj.02-0243fje · Cited by 91 · see citing works

Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats

Irako, T., Akamizu, T., Hosoda, H., Iwakura, H., Ariyasu, H., Tojo, Κ., Tajima, N., & Kangawa, K. (2006) · Diabetologia · doi:10.1007/s00125-006-0226-3 · Cited by 88 · see citing works

GLP-1 Receptor Agonist and Non-Alcoholic Fatty Liver Disease

Lee, J., Hong, S.-W., Rhee, E.-J., & Lee, W.-Y. (2012) · Diabetes &amp; Metabolism Journal · doi:10.4093/dmj.2012.36.4.262 · Cited by 87 · see citing works

Serotonin Deficiency Is Associated With Delayed Gastric Emptying

Wei, L., Singh, R., Ha, S. E., Martin, A. M., Jones, L. A., Jin, B., Jorgensen, B. G., Zogg, H., Chervo, T. C., Gottfried‐Blackmore, A., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.02.060 · Cited by 85 · see citing works

Hepatic functions of GLP-1 and its based drugs: current disputes and perspectives

Jin, T., & Weng, J. (2016) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00069.2016 · Cited by 83 · see citing works

Effect of Antibodies to Somatostatin on Acid Secretion and Gastrin Release by the Isolated Perfused Rat Stomach

Short, G. M., Doyle, J. W., & Wolfe, M. M. (1985) · Gastroenterology · doi:10.1016/s0016-5085(85)80018-4 · Cited by 81 · see citing works

Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity

Gallwitz, B. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1004044 · Cited by 81 · see citing works

Gastric inhibitory polypeptide enhancement of the insulin effect on fatty acid incorporation into adipose tissue in the rat

Beck, B., & Max, J. (1983) · Regulatory Peptides · doi:10.1016/0167-0115(83)90276-8 · Cited by 79 · see citing works

Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery

Ratner, C., Skov, L. J., Raida, Z., Bächler, T., Bellmann‐Sickert, K., Foll, C. L., Sivertsen, B., Dalbøge, L. S., Hartmann, B., Beck‐Sickinger, A. G., et al. (2016) · Endocrinology · doi:10.1210/en.2016-1329 · Cited by 73 · see citing works

Dual inhibitory pathways link antral somatostatin and histamine secretion in human, dog, and rat stomach

Vuyyuru, L., Schubert, M. L., Harrington, L., Arimura, A., & Makhlouf, G. M. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90645-2 · Cited by 72 · see citing works

Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells

Billing, L., Smith, C. A., Larraufie, P., Goldspink, D. A., Galvin, S. G., Kay, R. G., Howe, J. D., Walker, R., Pruna, M., Glasssmith, L. L., et al. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.07.011 · Cited by 72 · see citing works

GLP-1 receptor agonists in NAFLD

Petit, J.-M., & Vergès, B. L. (2017) · Diabetes & Metabolism · doi:10.1016/s1262-3636(17)30070-8 · Cited by 71 · see citing works

The Role of Gastrointestinal Hormones in Hepatic Lipid Metabolism

Mells, J. E., & Anania, F. A. (2013) · Seminars in Liver Disease · doi:10.1055/s-0033-1358527 · Cited by 70 · see citing works

Mechanism of Action of Glucagon-Like Peptide-2 to Increase IGF-I mRNA in Intestinal Subepithelial Fibroblasts

Leen, J., Izzo, A. A., Upadhyay, C., Rowland, K., Dubé, P. E., Gu, S., Heximer, S. P., Rhodes, C. J., Storm, D. R., Lund, P. K., et al. (2010) · Endocrinology · doi:10.1210/en.2010-0822 · Cited by 70 · see citing works

Physiological roles of the GIP receptor in murine brown adipose tissue

Beaudry, J. L., Kaur, K. D., Varin, E. M., Baggio, L. L., Cao, X., Mulvihill, E. E., Bates, H. E., Campbell, J. E., & Drucker, D. J. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.08.006 · Cited by 70 · see citing works

GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue

Campbell, J. E., Beaudry, J. L., Svendsen, B., Baggio, L. L., Gordon, A. N., Ussher, J. R., Wong, C. K., Gribble, F. M., D’Alessio, D. A., Reimann, F. M., et al. (2022) · Diabetes · doi:10.2337/db21-1166 · Cited by 70 · see citing works

GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior

Samms, R. J., Cosgrove, R., Snider, B. M., Furber, E. C., Droz, B. A., Briere, D. A., Dunbar, J. D., Dogra, M., Alsina‐Fernandez, J., Borner, T., et al. (2022) · Diabetes · doi:10.2337/db21-0848 · Cited by 69 · see citing works

GIP receptor mRNA expression in different fat tissue depots in postmenopausal non-diabetic women

Rudovich, N. N., Kaiser, S., Engeli, S., Osterhoff, M. A., Gögebakan, Ö., Blüher, M., & Pfeiffer, A. F. H. (2007) · Regulatory Peptides · doi:10.1016/j.regpep.2007.02.006 · Cited by 68 · see citing works

Synthetic Gastric Inhibitory Polypeptide Stimulatory Effect on Insulin and Glucagon Secretion in the Rat

Taminato, T., Seino, Y., Goto, Y., Inoue, Y., Kadowaki, S., Mori, K., Nozawa, M., Yajima, H., & Imura, H. (1977) · Diabetes · doi:10.2337/diab.26.5.480 · Cited by 68 · see citing works

A brainstem circuit for nausea suppression

Zhang, C., Vincelette, L. K., Reimann, F., & Liberles, S. D. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110953 · Cited by 68 · see citing works

Enteroendocrine cell types that drive food reward and aversion

Bai, L., Sivakumar, N., Yu, S., Mesgarzadeh, S., Ding, T., Ly, T., Corpuz, T. V., Grove, J. C. R., Jarvie, B. C., & Knight, Z. A. (2022) · eLife · doi:10.7554/elife.74964 · Cited by 67 · see citing works

Secretin activates brown fat and induces satiation

Laurila, S., Sun, L., Lahesmaa, M., Schnabl, K., Laitinen, K., Klén, R., Li, Y., Baláž, M., Wolfrum, C., Steiger, K., et al. (2021) · Nature Metabolism · doi:10.1038/s42255-021-00409-4 · Cited by 66 · see citing works

GLP ‐1 analogue prevents NAFLD in ApoE KO mice with diet and Acrp30 knockdown by inhibiting c‐ JNK

Zhang, L., Yang, M., Ren, H., Hu, H., Boden, G. H., Li, L., & Yang, G. (2013) · Liver International · doi:10.1111/liv.12120 · Cited by 65 · see citing works

GIP and GLP-1: stepsiblings rather than monozygotic twins within the incretin family

Nauck, M. A., & Meier, J. J. (2019) · Diabetes · doi:10.2337/dbi19-0005 · Cited by 65 · see citing works

Peptone‐mediated glucagon‐like peptide‐1 secretion depends on intestinal absorption and activation of basolaterally located Calcium‐Sensing Receptors

Modvig, I. M., Kuhre, R. E., & Holst, J. J. (2019) · Physiological Reports · doi:10.14814/phy2.14056 · Cited by 63 · see citing works

Enteroendocrine Dynamics – New Tools Reveal Hormonal Plasticity in the Gut

Beumer, J., Gehart, H., & Clevers, H. C. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa018 · Cited by 63 · see citing works

Gastrointestinal hormones and the regulation of β‐cell mass

Lavine, J. A., & Attie, A. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05802.x · Cited by 61 · see citing works

Pharmacological Characterization of Apraglutide, a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist, for the Treatment of Short Bowel Syndrome

Hargrove, D. M., Alagarsamy, S., Croston, G. E., Laporte, R., Qi, S., Srinivasan, K., Sueiras-Diaz, J., Wiśniewski, K., Hartwig, J., Lu, M., et al. (2020) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.119.262238 · Cited by 61 · see citing works

Selective stimulation of colonic L cells improves metabolic outcomes in mice

Lewis, J. E., Miedzybrodzka, E. L., Foreman, R. E., Woodward, O. R. M., Kay, R. G., Goldspink, D. A., Gribble, F. M., & Reimann, F. (2020) · Diabetologia · doi:10.1007/s00125-020-05149-w · Cited by 59 · see citing works

Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT

Alssema, M., Rijkelijkhuizen, J. M., Holst, J. J., Teerlink, T., Scheffer, P. G., Eekhoff, E. M. W., Gastaldelli, A., Mari, A., Hart, L. M. ‘., Nijpels, G., et al. (2013) · European Journal of Endocrinology · doi:10.1530/eje-13-0487 · Cited by 58 · see citing works

Models and Tools for Studying Enteroendocrine Cells

Goldspink, D. A., Reimann, F. M., & Gribble, F. M. (2018) · Endocrinology · doi:10.1210/en.2018-00672 · Cited by 51 · see citing works

Favorable Effects of GLP-1 Receptor Agonist against Pancreatic β-Cell Glucose Toxicity and the Development of Arteriosclerosis: “The Earlier, the Better” in Therapy with Incretin-Based Medicine

Kaneto, H., Kimura, T., Shimoda, M., Obata, A., Sanada, J., Fushimi, Y., Nakanishi, S., Mune, T., & Kaku, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157917 · Cited by 51 · see citing works

GLP-1 Elicits an Intrinsic Gut–Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance

Khound, R., Taher, J., Baker, C., Adeli, K., & Su, Q. (2017) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.310251 · Cited by 50 · see citing works

Dose-dependent effects of cholecystokinin-8 on antropyloroduodenal motility, gastrointestinal hormones, appetite, and energy intake in healthy men

Brennan, I. M., Little, T. J., Feltrin, K. L., Smout, A. J. P. M., Wishart, J. M., Horowitz, M., & Feinle‐Bisset, C. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90791.2008 · Cited by 46 · see citing works

Synergistic effects of dopamine agonists and centrally administered neurotensin on feeding

Hawkins, M. F., Barkemeyer, C. A., & Tulley, R. T. (1986) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(86)90170-x · Cited by 45 · see citing works

The role of GLP-1 receptor agonists in managing type 2 diabetes

Nachawi, N., Rao, P. P., & Makin, V. (2022) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.89a.21110 · Cited by 45 · see citing works

Gut hormones

Bloom, S. R., & Polak, J. M. (1978) · Proceedings of The Nutrition Society · doi:10.1079/pns19780037 · Cited by 45 · see citing works

Gut peptide regulation of food intake – evidence for the modulation of hedonic feeding

Woodward, O. R. M., Gribble, F. M., Reimann, F., & Lewis, J. E. (2021) · The Journal of Physiology · doi:10.1113/jp280581 · Cited by 44 · see citing works

Novel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice

Wismann, P., Pedersen, S. L., Hansen, G., Mannerstedt, K., Pedersen, P. J., Jeppesen, P. B., Vrang, N., Fosgerau, K., & Jelsing, J. (2018) · Physiology &amp; Behavior · doi:10.1016/j.physbeh.2018.03.004 · Cited by 43 · see citing works

High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells

Beumer, J., Puschhof, J., Bauzá‐Martinez, J., Martínez-Silgado, A., Elmentaite, R., James, K. R., Ross, A., Hendriks, D. F. G., Artegiani, B., Busslinger, G. A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.08.005 · Cited by 43 · see citing works

Metabolic responses and benefits of glucagon‐like peptide‐1 (GLP‐1) receptor ligands

Tanday, N., Flatt, P. R., & Irwin, N. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15485 · Cited by 42 · see citing works

Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

Modvig, I. M., Andersen, D. B., Grunddal, K. V., Kuhre, R. E., Martinussen, C., Christiansen, C. B., Ørskov, C., Larraufie, P., Kay, R. G., Reimann, F. M., et al. (2020) · International Journal of Obesity · doi:10.1038/s41366-020-0541-7 · Cited by 41 · see citing works

Physiological functions and potential clinical applications of motilin

Mori, H., Verbeure, W., Tanemoto, R., Sosoranga, E. R., & Tack, J. F. (2022) · Peptides · doi:10.1016/j.peptides.2022.170905 · Cited by 38 · see citing works

Gut peptide regulation of food intake - evidence for the modulation of hedonic feeding.

Woodward, O. R. M., Gribble, F. M., Reimann, F. M., & Lewis, J. E. (2021) · Apollo (University of Cambridge) · doi:10.17863/cam.74301 · Cited by 38 · see citing works

Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice

Boland, B. B., Mumphrey, M. B., Zheng, H., Townsend, R. L., Gill, B. M., Oldham, S. N., Will, S., Morrison, C. D., Yu, S., Münzberg, H., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.05.004 · Cited by 36 · see citing works

Distribution and Stimulus Secretion Coupling of Enteroendocrine Cells along the Intestinal Tract

Adriaenssens, A. E., Reimann, F. M., & Gribble, F. M. (2018) · Comprehensive physiology · doi:10.1002/cphy.c170047 · Cited by 35 · see citing works

Recent advances of GIP and future horizons

Holst, J. J., & ROSENKILDE, M. M. (2019) · Peptides · doi:10.1016/j.peptides.2019.170230 · Cited by 33 · see citing works

Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice

Keyhani‐Nejad, F., Irmler, M., Isken, F., Wirth, E. K., Beckers, J., Birkenfeld, A. L., & Pfeiffer, A. F. H. (2014) · Diabetologia · doi:10.1007/s00125-014-3423-5 · Cited by 33 · see citing works

5 Gut hormones in gastric function

Lloyd, K. C. K. (1994) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(05)80228-9 · Cited by 32 · see citing works

GLP-1(32–36)amide, a novel pentapeptide cleavage product of GLP-1, modulates whole body glucose metabolism in dogs

Elahi, D., Angeli, F. S., Vakilipour, A., Carlson, O. D., Tomás, E., Egan, J. M., Habener, J. F., & Shannon, R. P. (2014) · Peptides · doi:10.1016/j.peptides.2014.06.004 · Cited by 29 · see citing works

Apraglutide, a novel once‐weekly glucagon‐like peptide‐2 analog, improves intestinal fluid and energy absorption in patients with short bowel syndrome: An open‐label phase 1 and 2 metabolic balance trial

Eliasson, J., Hvistendahl, M., Freund, N., Bolognani, F., Meyer, C., & Jeppesen, P. B. (2022) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.2362 · Cited by 26 · see citing works

Direct metabolic effects of gastric inhibitory polypeptide (GIP): dissociation at physiological levels of effects on insulin-stimulated fatty acid and glucose incorporation in rat adipose tissue

Beck, B., & Max, J. (1986) · Diabetologia · doi:10.1007/bf02427284 · Cited by 25 · see citing works

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

Loh, J. S., Mak, W. Q., Tan, L. K. S., Ng, C. X., Chan, H. H., Yeow, S. H., Foo, J. B., Ong, Y. S., How, C. W., & Khaw, K. Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01743-1 · Cited by 1,193 · see citing works

Integrative metabolism in MASLD and MASH: Pathophysiology and emerging mechanisms

Steinberg, G. R., Valvano, C. M., De Nardo, W., & Watt, M. J. (2025) · Journal of Hepatology · doi:10.1016/j.jhep.2025.02.033 · Cited by 240 · see citing works

Graphic, Quantitation, Visualization, Standardization, Digitization, and Intelligence of Electrolyte and Electrolyte‐Electrode Interface

Cai, T., Wang, Y., Zhao, F., Ma, Z., Kumar, P., Xie, H., Sun, C., Wang, J., Li, Q., Guo, Y., et al. (2024) · Advanced Energy Materials · doi:10.1002/aenm.202400569 · Cited by 94 · see citing works

Bile acid metabolism in type 2 diabetes mellitus

Sandoval, M. C., & Haeusler, R. A. (2025) · Nature Reviews Endocrinology · doi:10.1038/s41574-024-01067-8 · Cited by 53 · see citing works

Bitter taste receptors as sensors of gut luminal contents

Sternini, C., & Rozengurt, E. (2024) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-024-01005-z · Cited by 58 · see citing works

The Critical Role of the Bile Acid Receptor TGR5 in Energy Homeostasis: Insights into Physiology and Therapeutic Potential

Zangerolamo, L., Carvalho, M. U. W. B. D., & Barbosa, H. C. L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26146547 · Cited by 54 · see citing works

Inter-organ communication is a critical machinery to regulate metabolism and aging

Tokizane, K., & Imai, S. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.11.013 · Cited by 42 · see citing works

Amylin, Another Important Neuroendocrine Hormone for the Treatment of Diabesity

Eržen, S., Tonin, G., Jurišić‐Eržen, D., & Klen, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031517 · Cited by 38 · see citing works

Gut hormones and appetite regulation

Hong, S.-H., & Choi, K. M. (2024) · Current Opinion in Endocrinology, Diabetes &amp; Obesity · doi:10.1097/med.0000000000000859 · Cited by 35 · see citing works

Interkingdom signaling between gastrointestinal hormones and the gut microbiome

Zhao, X., Qiu, Y., Liang, L., & Fu, X. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2456592 · Cited by 31 · see citing works

Gut hormones and bone homeostasis: potential therapeutic implications

Bouvard, B., & Mabilleau, G. (2024) · Nature Reviews Endocrinology · doi:10.1038/s41574-024-01000-z · Cited by 26 · see citing works

Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation

Singh, P. N. P., Gu, W., Madha, S., Lynch, A. W., Cejas, P., He, R., Bhattacharya, S., Gomez, M. M., Oser, M. G., Brown, M. A., et al. (2024) · Cell stem cell · doi:10.1016/j.stem.2024.04.015 · Cited by 25 · see citing works

Piezo channels in the intestinal tract

He, H., Zhou, J., Xu, X., Zhou, P., Zhong, H., & Liu, M. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1356317 · Cited by 24 · see citing works

The emerging role of gut hormones

Cho, H., & Lim, J. (2024) · Molecules and Cells · doi:10.1016/j.mocell.2024.100126 · Cited by 26 · see citing works

Bile acids as a key target: traditional Chinese medicine for precision management of insulin resistance in type 2 diabetes mellitus through the gut microbiota-bile acids axis

Wang, Y., Yu, J., Chen, B., Jin, W., Wang, M., Chen, X., Jian, M., Sun, L., & Piao, C. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1481270 · Cited by 24 · see citing works

Update on the pathogenesis of endometriosis-related infertility based on contemporary evidence

Qi, Q., Li, Y., Chen, Z., Luo, Z., Zhou, T., Zhou, J., Zhang, Y., Chen, S., & Wang, L. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1558271 · Cited by 24 · see citing works

Vagal Sensory Gut–Brain Pathways That Control Eating—Satiety and Beyond

Méndez‐Hernández, R., Braga, I., Bali, A. P., Yang, M., & de Lartigue, G. (2025) · Comprehensive physiology · doi:10.1002/cph4.70010 · Cited by 21 · see citing works

Cellular and molecular basis of proximal small intestine disorders

Bildstein, T., Charbit‐Henrion, F., Azabdaftari, A., Cerf–Bensussan, N., & Uhlig, H. H. (2024) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-024-00962-9 · Cited by 23 · see citing works

Transcutaneous Auricular Vagus Nerve Stimulation to Improve Emotional State

Ruiz, A. A. (2024) · Biomedicines · doi:10.3390/biomedicines12020407 · Cited by 24 · see citing works

The role of the gut microbiome in disorders of gut–brain interaction

Gawey, B. J., Mars, R. A. T., & Kashyap, P. (2024) · FEBS Journal · doi:10.1111/febs.17200 · Cited by 28 · see citing works

Paeoniflorin: a review of its pharmacology, pharmacokinetics and toxicity in diabetes

Ou, X., Yu, Z., Pan, C., Zheng, X., Li, D., Qiao, Z., & Zheng, X. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1551368 · Cited by 22 · see citing works

Intestine-Settled Electrospun Short-Fibers Modulate Epithelial Transport Proteins to Reduce Purine and Glucose Uptake

Tang, Y., Wang, J., Cai, Z., Sarmento, B. F. C. C., Du, Y., & Cui, W. (2024) · Advanced Fiber Materials · doi:10.1007/s42765-024-00475-9 · Cited by 20 · see citing works

Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors

Wang, Q., Chen, Z., Zhang, G., Yang, J., Hu, R., Yao, T., Zeng, C., Zhang, S., Jiang, W., Zhu, S., et al. (2026) · Science · doi:10.1126/science.adu7686 · Cited by 19 · see citing works

Necrotizing Enterocolitis and Neurodevelopmental Impairments: Microbiome, Gut, and Brain Entanglements

Sha, C., Jin, Z., Ku, S. Y., Kogosov, A. S., Yu, S., Bergese, S. D., & Hsieh, H. V. (2024) · Biomolecules · doi:10.3390/biom14101254 · Cited by 18 · see citing works

Exploring Gut Microbiota in Systemic Lupus Erythematosus: Insights and Biomarker Discovery Potential

Jin, L., Xiao, J., Luo, Y., Duan, L., Gong, Y., Li, Y., Wang, H., Qiu, Y., Wang, H., Lai, W., et al. (2025) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-025-09051-4 · Cited by 19 · see citing works

Advances in the research of comorbid insomnia and depression: mechanisms, impacts, and interventions

Gao, T., Xiang, H., Wu, Q. N., Zhu, L. S., Pei, W. J., Fu, W. J., & Chou, T. S. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1468212 · Cited by 17 · see citing works

Natural remedies proposed for the management of diabetic retinopathy (DR): diabetic complications

Khidr, E. G., Morad, N. I., Hatem, S., El‐Dessouki, A. M., Mohamed, A. F., El‐Shiekh, R. A., Hafeez, M. S. A. E., & Ghaiad, H. R. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-03866-w · Cited by 17 · see citing works

Microbiota-Dependent Upregulation of Bitter Taste Receptor Subtypes in the Mouse Large Intestine in High-Fat Diet-Induced Obesity

Caremoli, F., Huynh, J., Lagishetty, V., Markovic, D., Braun, J. G., Dong, T. S., Jacobs, J. P., & Sternini, C. (2023) · Nutrients · doi:10.3390/nu15194145 · Cited by 15 · see citing works

The taste for health: the role of taste receptors and their ligands in the complex food/health relationship

Morini, G. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1396393 · Cited by 14 · see citing works

Gastrointestinal function and nutritional interventions in septic shock

Bachmann, K. F., Cotoia, A., & Reintam Blaser, A. (2025) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000001302 · Cited by 13 · see citing works

Advances in small-molecule insulin secretagogues for diabetes treatment

Su, J., Xu, J., Hu, S., Ye, H., Xie, L. N., & Ouyang, S. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117179 · Cited by 13 · see citing works

The 5-HT-related gut-brain axis in obesity.

Jiang, C., Zhan, Q., & Zeng, C. (2024) · Life Science · doi:10.1016/j.lfs.2024.123171 · Cited by 12 · see citing works

Intestinal retentive delivery system for improved disease therapy

Wu, X., Wu, W., Jutaek, N., Rong, L., & Han, K. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113903 · Cited by 12 · see citing works

Stress, microbiota, and the gut–brain axis in mental and digestive health

Santos, J., Maran, P. L., & Rodríguez‐Urrutia, A. (2025) · Medicina Clínica · doi:10.1016/j.medcli.2024.11.023 · Cited by 15 · see citing works

The Role of Somatostatin in the Gastrointestinal Tract

Papantoniou, K., Aggeletopoulou, I., Pastras, P., & Triantos, C. K. (2025) · Biology · doi:10.3390/biology14050558 · Cited by 13 · see citing works

Effects of cortisone in zebrafish (Danio rerio): Insights into gut microbiota interactions and molecular mechanisms underlying DNA damage and apoptosis

Tan, J., Lihua, Y., Ye, M., Geng, Y., Guo, Y., Zou, H., & Hou, L. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.135576 · Cited by 11 · see citing works

Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

Zhang, M., Wu, X., Liu, D., Li, H., Li, X., Yang, W., Ye, J., Hou, L., Wang, S., Ning, N., et al. (2026) · Cell stem cell · doi:10.1016/j.stem.2026.01.002 · Cited by 11 · see citing works

Small Intestinal Endocrine Cell Derived Exosomal ACE2 Protects Islet β-Cell Function by Inhibiting the Activation of NLRP3 Inflammasome and Reducing β-Cell Pyroptosis

Yang, S., Cao, J., Wang, Y., Chen, Q., Li, F., Gao, Y., Li, R., & Li, Y. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s450337 · Cited by 10 · see citing works

A new perspective in intestinal microecology: lifting the veil of exercise regulation of cardiometabolic diseases

Gao, C., Wei, J., Lu, C., Wang, L., Dong, D. F., & Sun, M. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2404141 · Cited by 10 · see citing works

The Interplay between the Gut and Ketogenic Diets in Health and Disease

Mu, C., Rho, J. M., & Shearer, J. (2025) · Advanced Science · doi:10.1002/advs.202504249 · Cited by 11 · see citing works

Microbiota and enteric nervous system crosstalk in diabetic gastroenteropathy: bridging mechanistic insights to microbiome-based therapies

Tao, W., Yu, Y., Tan, D., Huang, X., Huang, J., Lin, C., & Yu, R. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1603442 · Cited by 9 · see citing works

Limosilactobacillus reuteri promotes the expression and secretion of enteroendocrine‐ and enterocyte‐derived hormones

Rienzi, S. C. D., Danhof, H. A., Forshee, M. D., Roberts, A., & Britton, R. A. (2025) · The FASEB Journal · doi:10.1096/fj.202401669r · Cited by 9 · see citing works

The sympathetic neurons in the gut: Perspectives on metabolic and immune health and diseases

Wan, Y., Cao, C., & Zeng, W. (2025) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2025.103051 · Cited by 9 · see citing works

Innovative Molecules and Delivery Technologies Enabling the Future of GLP-1-based Therapies

Xu, Y., Drucker, D. J., Traverso, G., & Beloqui, A. (2025) · Endocrine Reviews · doi:10.1210/endrev/bnaf027 · Cited by 9 · see citing works

Crystallinity of starch, food composition, and digestibility of starch

Šárka, E., Smrčková, P., & Sluková, M. (2025) · Czech Journal of Food Sciences · doi:10.17221/33/2025-cjfs · Cited by 5 · see citing works

Regulation of pancreatic β cells by exosomes from different sources

Gao, Y., Chen, Q., Wu, Z., & Li, Y. (2025) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2025.112222 · Cited by 8 · see citing works

Puerarin as a Phytochemical Modulator of Gastrointestinal Homeostasis in Livestock: Molecular Mechanisms and Translational Applications

Zhou, J., Lv, J., Chen, X., Li, T., Shen, J., Wang, Z., Dai, C., & Hao, Z. (2025) · Antioxidants · doi:10.3390/antiox14060756 · Cited by 8 · see citing works

Assessment of Endocrine-Disrupting Properties in Cosmetic Ingredients: Focus on UV Filters and Alternative Testing Methods

Maddaleno, A. S., Guardia-Escote, L., Vinardell, M. P., Teixidó, E., & Mitjans, M. (2025) · Cosmetics · doi:10.3390/cosmetics12040175 · Cited by 8 · see citing works

The gut–adipose/pancreas axis: a novel perspective on glycolipid metabolism dysregulation in MAFLD and T2DM pathogenesis

Liang, J., Chen, X., Chu, Y., & Leng, Y. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1664233 · Cited by 8 · see citing works

Gut-brain communication: nerve circuits and chemical messengers of colorectal motility and defection control

Han, M. N., Furness, J. B., Ringuet, M. T., Montenegro, E., Wu, H., Hossain, M. A., Diwakarla, S., Dehkhoda, F., & Furness, S. G. B. (2025) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00212.2025 · Cited by 8 · see citing works

Roles of organokines in intervertebral disc homeostasis and degeneration

He, Y., Liu, S., Lin, H., Ding, F., Shao, Z., & Xiong, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1340625 · Cited by 7 · see citing works

Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice

Harada, K., Wada, E., Osuga, Y., Shimizu, K., Uenoyama, R., Hirai, M. Y., Maekawa, F., Miyazaki, M., Hayashi, Y. K., Nakamura, K., et al. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.102072 · Cited by 7 · see citing works

Intestinal Butyrate Ameliorates Rheumatoid Arthritis Through Promoting the Expression of Cortistatin in Ileum via HDAC3 —Vitamin D Receptor Pathway

Liao, M., Zhu, Y., Cui, Q., Yue, M., Li, J., Gao, L., He, Y., Guo, Y., Zhang, W., Wei, Z., et al. (2025) · Immunology · doi:10.1111/imm.13939 · Cited by 7 · see citing works

Lactobacillus rhamnosus GG Supernatant Improves GLP-1 Secretion Through Attenuating L Cell Lipotoxicity and Modulating Gut Microbiota in Obesity

Wang, X., Lv, X., Qi, Y., Wang, S., Yang, M., Wang, B., Cao, H., Zhang, J., & Xu, X. J. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10564-9 · Cited by 7 · see citing works

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cheng, Z., Wu, Z., Wu, M., Xie, L., & Chen, Q. (2025) · Cell Proliferation · doi:10.1111/cpr.70112 · Cited by 7 · see citing works

Modulation of Intestinal Flora: a Novel Immunotherapeutic Approach for Enhancing Thyroid Cancer Treatment

Huang, W., Jiang, T., He, J., Ruan, J., Wu, B., Tao, R., Xu, P., Wang, Y., Chen, R., Wang, H., et al. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10471-z · Cited by 7 · see citing works

Incretin hormones and obesity

Alcaino, C., Reimann, F. M., & Gribble, F. M. (2024) · The Journal of Physiology · doi:10.1113/jp286293 · Cited by 7 · see citing works

Titanium dioxide nanoparticles disturb glucose homeostasis in association with impaired enteroendocrine cell differentiation

Zou, K., Du, L., Qin, J., Zhou, J., Xiao, Y., Song, X., Liu, H., & Xiu, W. (2025) · Food and Chemical Toxicology · doi:10.1016/j.fct.2025.115504 · Cited by 6 · see citing works

Advanced strategies in organoid/organ-on-a-chip for food safety and nutrition

Zhou, Y., Wang, F., Zhao, R., Huang, T., Su, W., Wen, Y., He, Z., & Li, D. (2025) · Food Research International · doi:10.1016/j.foodres.2025.117011 · Cited by 6 · see citing works

Emerging role of E4BP4/NFIL3 in metabolic homeostasis

Ran, S., Wang, S., Jin, Q., Liu, G., Xue, X., Qu, P., Peng, L., & Meng, H. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156390 · Cited by 5 · see citing works

Unraveling the potential of microalgae as nutrient sources for gut health enhancement: Insights from the perspective of gut microbiota

Wang, P., Chen, M., Liu, C., & Zheng, L. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.105427 · Cited by 5 · see citing works

Unlocking the Potential of Taste and Taste-active Peptides: Bridging Structural Characteristics and Biological Activities with Food and Pharmaceutical Applications

Xiang, H., Song, W., Hao, S., & Sun‐Waterhouse, D. (2026) · Journal of Future Foods · doi:10.1016/j.jfutfo.2025.12.020 · Cited by 5 · see citing works

Effects of Dietary Clostridium butyricum on Growth and Intestinal Mucosal Barrier Functions of Juvenile Channel Catfish (Ictalurus punctatus)

Guo, Z., Qian, Y., Peng, X., Qin, C., Ren, H., Du, J., Huang, C., Pan, M., & Ou, W. (2025) · Microorganisms · doi:10.3390/microorganisms13051061 · Cited by 5 · see citing works

Role of fermentation-resistant and non-fermentable fibers in gastrointestinal health: mechanisms, benefits, and challenges

Modasia, A. A., Spiller, R. C., & Warren, F. J. (2026) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2025.2612556 · Cited by 4 · see citing works

A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA

Li, D., Chen, Y., Zhu, X., Yang, Y., Li, H., & Zhao, R. C. (2025) · Journal of Biomedical Science · doi:10.1186/s12929-024-01098-3 · Cited by 4 · see citing works

Casein Hydrolysate Enhances Upper Gastrointestinal Chemosensing and Gastric Acid Secretion in Pigs

Mu, C., Shen, J., Wang, H., Yu, K., Su, Y., & Zhu, W. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c01141 · Cited by 4 · see citing works

Ingestive Behavior and Precision Nutrition: Part of the Puzzle

Biruete, A., Buobu, P. S., Considine, R. V., Hoxha, E. M., Eicher‐Miller, H. A., Kinzig, K. P., Panjwani, A. A., Running, C. A., Rutigliani, G., Savaiano, D. A., et al. (2025) · Advances in Nutrition · doi:10.1016/j.advnut.2025.100531 · Cited by 6 · see citing works

ETV1 is a key regulator of enteroendocrine PYY production

Baattrup, A. M., Pedersen, M. T., Hansen, S. L., Maimets, M., Gribble, F. M., Reimann, F. M., & Jensen, K. B. (2025) · Disease Models & Mechanisms · doi:10.1242/dmm.052610 · Cited by 4 · see citing works

Motilin fluctuations in healthy volunteers determined by liquid chromatography mass spectrometry

Foreman, R. E., Bannon, C. A. M., Kay, R. G., Reimann, F. M., & Gribble, F. M. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1348146 · Cited by 4 · see citing works

Microprotein-encoding RNA regulation in cells treated with pro-inflammatory and pro-fibrotic stimuli

Pai, V. J., Lau, C. J., García‐Ruiz, A., Donaldson, C. J., Vaughan, J. M., Miller, B., de Souza, E. V., Pinto, A. F. M., Diedrich, J. K., Gavva, N. R., et al. (2024) · BMC Genomics · doi:10.1186/s12864-024-10948-1 · Cited by 4 · see citing works

Integration of signal transduction pathways in sensory epithelial enteroendocrine cells

Bellampalli, S. S., Joshi, V., Fonar, G., & Beyder, A. (2025) · Molecular Biology of the Cell · doi:10.1091/mbc.e24-03-0143 · Cited by 3 · see citing works

Spatiotemporal coordination between local flux and systemic homeostasis in the small intestine

Zhang, J., Zhang, S., Du, L., Zhao, Y., & Wang, D. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.07.009 · Cited by 3 · see citing works

Dynamic multi-omics profiling of islet and gut hormonal secretion and peripheral crosstalk in response to various nutrient loads

Wang, J., Liu, L., Liu, H., Qian, Y., Zhang, S., Zheng, S., Jiang, H., Zhou, Y., Cheng, X., Fu, Q., et al. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102327 · Cited by 3 · see citing works

Calcium-Sensing Receptor Regulation of Gastrointestinal Hormone Secretion

Anjom-Shoae, J., Veedfald, S., Conigrave, A. D., Horowitz, M., & Feinle‐Bisset, C. (2025) · Endocrine Reviews · doi:10.1210/endrev/bnaf040 · Cited by 3 · see citing works

Identification of intestinal enteroendocrine cell subtypes and their associated hormones in zebrafish

Morash, M., Kay, R. G., Soderblom, E. J., MacLean, G. H., Wen, J., Moore, P. J., Lickwar, C. R., Shah, M. A., Ganz, J., Gribble, F. M., et al. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003522 · Cited by 5 · see citing works

Role of exosomes in gastrointestinal physiology and pathophysiology

Wellington, V. N. A., & Singh, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1717977 · Cited by 3 · see citing works

Effects of microplastics on the intestines

Jarmakiewicz-Czaja, S., Ferenc, K., Sokal-Dembowska, A., Wojdyła, D., & Filip, R. (2026) · BMC Gastroenterology · doi:10.1186/s12876-026-04749-x · Cited by 4 · see citing works

AI digital-twin ecosystem translating gut-microbiome–neuroimmune signals into precision sleep–mood interventions

Yu, X., Fan, L., Fan, S., & Hong, L. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1703605 · Cited by 3 · see citing works

The gut–joint axis in osteoarthritis

Wei, J. H., Zhang, Y., Xie, C., Lei, G., & Zeng, C. (2026) · Nature Reviews Rheumatology · doi:10.1038/s41584-026-01378-2 · Cited by 3 · see citing works

Gut microbiota in health and disease

Li, Y. N., Xiao, X., Jiang, X., Li, X., WANG, W., & Lin, R. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00512-6 · Cited by 4 · see citing works

Intestinal perfusion of unacylated ghrelin alleviated metabolically associated fatty liver disease in rats via a central glucagon-like peptide-1 pathway

Lv, P., Li, H., Li, X., Wang, X., Yu, J., & Gong, Y. (2024) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00217.2023 · Cited by 3 · see citing works

Dissecting the bidirectional associations between the progression of gastrointestinal and endocrine diseases

Liu, H., Si, S., Zhang, H., & Zhan, S. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1538603 · Cited by 2 · see citing works

Creb3l3 deficiency promotes intestinal lipid accumulation and alters ApoB-containing lipoprotein kinetics

Sweeney, D. W., Shen, M., & Farber, S. A. (2025) · Journal of Lipid Research · doi:10.1016/j.jlr.2025.100833 · Cited by 2 · see citing works

Duodenal mucosal ablation by irreversible electroporation: Modulating the gut-liver axis in metabolic steatotic liver disease

Ramírez-Mejía, M. M., & Méndez‐Sánchez, N. (2025) · World Journal of Hepatology · doi:10.4254/wjh.v17.i8.108845 · Cited by 2 · see citing works

Incretin Signaling Neighborhoods and Adverse Drug Reactions

Wright, S. C., Lindquist, P., ROSENKILDE, M. M., & Lauschke, V. M. (2025) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-062124-015046 · Cited by 3 · see citing works

Agrin at the crossroads of aging: A pleiotropic regulator in age-related diseases

Yuan, J., Zhang, S., Han, D., & Dong, X. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108131 · Cited by 2 · see citing works

Construction of liver organoid models by hepatobiliary differentiation from human induced pluripotent stem cells: state of the art, challenges and improving strategies

Wu, Y., Wang, Y., Zhang, W., Yuan, L.-L., & Chen, Y. (2026) · Stem Cell Research & Therapy · doi:10.1186/s13287-026-05080-8 · Cited by 2 · see citing works

Diabetes treatment by conversion of gut epithelial cells to insulin‐producing cells

Accili, D., Talchai, S. C., Bouchi, R., Lee, A. Y., Du, W. J., Kitamoto, T., McKimpson, W. M., Belvedere, S., & Lin, H. V. (2024) · Journal of Diabetes Investigation · doi:10.1111/jdi.14175 · Cited by 2 · see citing works

Glutamate from the microbiome controls host metabolism

Dréan, G. L., & Blottière, H. M. (2024) · Nature Metabolism · doi:10.1038/s42255-024-01050-7 · Cited by 2 · see citing works

Protective effect of the functional food containing Dendrobium officinale on menopausal syndromes based on gut microbiota and metabolomics analysis

Zheng, X., Jia, J., He, X., Zhou, C., Shao, Y.-T., Li, B., Lv, G., & Chen, S. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106275 · Cited by 2 · see citing works

Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cellsPreprint

Huang, Y., Mo, H., Yang, J., Gao, L., Tao, T., Shu, Q., Guo, W., Zhao, Y., Lyu, J., Wang, Q., et al. (2024) · eLife · doi:10.7554/elife.97854.3 · Cited by 24 · see citing works

Stress, microbiota, and the gut–brain axis in mental and digestive health

Santos, J., Maran, P. L., & Rodríguez‐Urrutia, A. (2025) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2024.11.006 · Cited by 4 · see citing works

Digestibility of starchPreprint

Šárka, E., Smrčková, P., & Sluková, M. (2024) · Preprints.org · doi:10.20944/preprints202405.0006.v1 · Cited by 2 · see citing works

Intestinal enteroendocrine cell subtype differentiation and hormone production in zebrafishPreprint

Morash, M., Kay, R. G., Soderblom, E. J., MacLean, G. H., Wen, J., Moore, P. J., Lickwar, C. R., Gribble, F. M., Reimann, F. M., Liddle, R. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.17.633579 · Cited by 2 · see citing works

Endocrine Properties of Microbiota

Sobol, K. V. (2024) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093024070019 · Cited by 1 · see citing works

Porcine jejunal-derived extracellular vesicles participate in the regulation of lipid metabolism

Fan, Y., Deng, H.-B., Zhu, J.-H., Luo, J.-Y., Chen, T., Sun, J.-J., Zhang, Y.-L., & Xi, Q. (2025) · Journal of Animal Science and Biotechnology · doi:10.1186/s40104-025-01185-x · Cited by 1 · see citing works

Intestinal Epithelial-Derived Exosomes Under Cold Stimulation Promote Adipose Thermogenesis

Han, X., Feng, T., Yang, Y., Zhu, Z., Shao, F., Sun, L., Yin, Y., & Zhang, W. (2025) · Metabolites · doi:10.3390/metabo15050324 · Cited by 1 · see citing works

Longitudinal multi-omics decipher chlorinated paraffin 52 disruption of gut-brain axis homeostasis in HFD-fed mice

Wang, Y., Dong, S., Zhang, Q., Zhang, R., Zhang, H., Huang, K., & Cheng, N. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.119307 · Cited by 1 · see citing works

Physical activity promotes gut adaptation, nutrient responsiveness, and sensitivity to gut peptides in male mice

Bæch‐Laursen, C., Ucin, J. V., Galsgaard, K. D., Llana, J., Kissow, H., Rehfeld, J. F., Holst, J. J., Pedersen, B. K., & Sanchís, P. (2026) · EBioMedicine · doi:10.1016/j.ebiom.2026.106152 · Cited by 1 · see citing works

Regulation of appetite via gut microbiota-modulated calcium ion channels: focus on tea polyphenols

Gao, J., Ho, C., & ZHANG, X. Y. (2026) · Food Research International · doi:10.1016/j.foodres.2026.119188 · Cited by 1 · see citing works

Targeting Enteroendocrine Cells to Treat Metabolic Disease

Roberts, A. G., Phuah, P., Cheng, S., & Murphy, K. G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00068-2 · Cited by 2 · see citing works

Intestinal Hormones

Cantini, G., Trabucco, M., Dicembrini, I., Mannucci, E., & Luconi, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813814-4.00016-x · Cited by 3 · see citing works

Function and mechanisms of enteroendocrine cells and gut hormones in metabolism

Gribble, F. M., & Reimann, F. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0168-8 · Cited by 670 · see citing works

Gut hormones beyond the gut: enteroendocrine control of systemic metabolism

Yu, L., Zhou, X., Ding, M., Lv, C., & Yu, Z. (2026) · Life Metabolism · doi:10.1093/lifemeta/loag030

The Regulation of Peripheral Metabolism by Gut-Derived Hormones

Sun, E. W. L., Martin, A. M., Young, R. L., & Keating, D. J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00754 · Cited by 71 · see citing works