Uchi, Hiroshi

An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway

Tsuji, G., Takahara, M., Uchi, H., Takeuchi, S., Mitoma, C., Moroi, Y., & Furue, M. (2011) · Journal of Dermatological Science

Toxic Organic Pollutants ImpactDermatology and Skin Diseases

Cited by 209

Role of AhR/ARNT system in skin homeostasis

Furue, M., Takahara, M., Nakahara, T., & Uchi, H. (2014) · Archives of Dermatological Research

Toxic Organic Pollutants ImpactDermatology and Skin Diseases

Cited by 175

Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect

Tsuji, G., Takahara, M., Uchi, H., Matsuda, T., Chiba, T., Takeuchi, S., Yasukawa, F., Moroi, Y., & Furue, M. (2012) · Journal of Investigative Dermatology

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

Cited by 169

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis

Tsuji, G., Hashimoto-Hachiya, A., Kiyomatsu-Oda, M., Takemura, M., Ohno, F., Ito, T., Morino-Koga, S., Mitoma, C., Nakahara, T., Uchi, H., et al. (2017) · Cell Death & Disease

Dermatology and Skin DiseasesGenetic and rare skin diseases.

Cited by 149

Gene regulation of filaggrin and other skin barrier proteins via aryl hydrocarbon receptor

Furue, M., Tsuji, G., Mitoma, C., Nakahara, T., Chiba, T., Morino-Koga, S., & Uchi, H. (2015) · Journal of Dermatological Science

Dermatology and Skin DiseasesToxic Organic Pollutants Impact

Cited by 132

Antioxidants for Healthy Skin: The Emerging Role of Aryl Hydrocarbon Receptors and Nuclear Factor-Erythroid 2-Related Factor-2

Furue, M., Uchi, H., Mitoma, C., Hashimoto-Hachiya, A., Chiba, T., Ito, T., Nakahara, T., & Tsuji, G. (2017) · Nutrients

Genomics, phytochemicals, and oxidative stressSkin Protection and Aging

Cited by 113

Inhibition of aryl hydrocarbon receptor signaling and induction of NRF2-mediated antioxidant activity by cinnamaldehyde in human keratinocytes

Uchi, H., Yasumatsu, M., Morino-Koga, S., Mitoma, C., & Furue, M. (2017) · Journal of Dermatological Science

Genomics, phytochemicals, and oxidative stressToxic Organic Pollutants Impact

Cited by 82

Antioxidant soybean tar Glyteer rescues T‐helper‐mediated downregulation of filaggrin expression via aryl hydrocarbon receptor

Takei, K., Mitoma, C., Hashimoto‐Hachiya, A., Uchi, H., Takahara, M., Tsuji, G., Kido‐Nakahara, M., Nakahara, T., & Furue, M. (2015) · The Journal of Dermatology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 81

Perillaldehyde inhibits AHR signaling and activates NRF2 antioxidant pathway in human keratinocytes

Fuyuno, Y., Uchi, H., Yasumatsu, M., Morino-Koga, S., Tanaka, Y., Mitoma, C., & Furue, M. (2018) · Oxidative Medicine and Cellular Longevity

Genomics, phytochemicals, and oxidative stressSkin Protection and Aging

Cited by 65

Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

Nakahara, T., Mitoma, C., Hashimoto-Hachiya, A., Takahara, M., Tsuji, G., Uchi, H., Yan, X., Hachisuka, J., Chiba, T., Esaki, H., et al. (2015) · Journal of Medicinal Food

Genomics, phytochemicals, and oxidative stressBotanical Research and Applications

Cited by 49