Veldhuis, Johannes D.

Impact of experimental blockade of peripheral growth hormone (GH) receptors on the kinetics of endogenous and exogenous GH removal in healthy women and men.

Veldhuis, J. D., Bidlingmaier, M., Anderson, S. M., Evans, W. S., Wu, Z., & Strasburger, C. J. (2002) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments

Cited by 61

Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women.

Bowers, C. Y., Granda, R., Mohan, S., Kuipers, J., Baylink, D., & Veldhuis, J. D. (2004) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 57

Glucose Stimulates Pulsatile Insulin Secretion from Human Pancreatic Islets by Increasing Secretory Burst Mass: Dose-Response Relationships

Ritzel, R. A., Veldhuis, J. D., & Butler, P. C. (2003) · The Journal of Clinical Endocrinology & Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 56

Circadian, Ultradian, and Episodic Release of β-Endorphin in Men, and Its Temporal Coupling with Cortisol*

IRANMANESH, A., LIZARRALDE, G., JOHNSON, M. L., & VELDHUIS, J. D. (1989) · The Journal of Clinical Endocrinology & Metabolism

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 56

Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator

Farhy, L. S., & Veldhuis, J. D. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 55

Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and β-cell mass to age-related insulin resistance in rats

Matveyenko, A. V., Veldhuis, J. D., & Butler, P. C. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 54

Complicating effects of highly correlated model variables on nonlinear least-squares estimates of unique parameter values and their statistical confidence intervals: estimating basal secretion and neurohormone half-life by deconvolution analysis.

Veldhuis, J. D., Evans, W. S., & Johnson, M. L. (1995) · Methods in Neurosciences

Statistical and numerical algorithmsControl Systems and Identification

Cited by 54

Gender, age, body mass index, and IGF-I individually and jointly determine distinct GH dynamics: analyses in one hundred healthy adults

Veldhuis, J. D., Roelfsema, F., Keenan, D. M., & Pincus, S. (2011) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments

Cited by 53

Growth hormone dynamics in healthy adults are related to age and sex and strongly dependent on body mass index

Roelfsema, F., & Veldhuis, J. D. (2016) · Neuroendocrinology

Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments

Cited by 53

Basal, Pulsatile, Entropic (Patterned), and Spiky (Staccato-like) Properties of ACTH Secretion: Impact of Age, Gender, and Body Mass Index

Veldhuis, J. D., Roelfsema, F., Iranmanesh, A., Carroll, B. J., Keenan, D. M., & Pincus, S. M. (2009) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 51

Retention of Estradiol Negative Feedback Relationship to LH Predicts Ovulation in Response to Caloric Restriction and Weight Loss in Obese Patients with Polycystic Ovary Syndrome

van Dam, E. W. C. M., Roelfsema, F., Veldhuis, J. D., Hogendoorn, S., Westenberg, J., Helmerhorst, F. M., Frölich, M., Krans, H. M. J., Meinders, A. E., & Pijl, H. (2004) · American Journal of Physiology-Endocrinology and Metabolism

Ovarian function and disordersHypothalamic control of reproductive hormones

Cited by 51

Joint pituitary-hypothalamic and intrahypothalamic autofeedback construct of pulsatile growth hormone secretion

Farhy, L. S., & Veldhuis, J. D. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 50

E2 Supplementation Selectively Relieves GH’s Autonegative Feedback on GH-Releasing Peptide-2-Stimulated GH Secretion

Anderson, S. M., Wideman, L., Patrie, J. T., Weltman, A., Bowers, C. Y., & Veldhuis, J. D. (2001) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 50

Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men

Veldhuis, J. D., Liu, P. Y., Keenan, D. M., & Takahashi, P. Y. (2012) · American Journal of Physiology-Endocrinology and Metabolism

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 48

Estradiol supplementation enhances submaximal feed-forward drive of growth hormone (GH) secretion by recombinant human GH-releasing hormone-1,44-amide in a putatively somatostatin-withdrawn milieu.

Veldhuis, J. D., Evans, W. S., & Bowers, C. Y. (2003) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 46

Thyrotropin secretion in mild and severe primary hypothyroidism is distinguished by amplified burst mass and basal secretion with increased spikiness and approximate entropy

Roelfsema, F., Pereira, A. M., Adriaanse, R., Endert, E., Fliers, E., Romijn, J. A., & Veldhuis, J. D. (2010) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 45

GH Does Not Modulate the Early Fasting-Induced Release of Free Fatty Acids in Mice

Steyn, F. J., Leong, J. W., Huang, L., Tan, H. Y., Xie, T. Y., Nelson, C., Waters, M. J., Veldhuis, J. D., Epelbaum, J., & Chen, C. (2012) · Endocrinology

Growth Hormone and Insulin-like Growth FactorsRegulation of Appetite and Obesity

Cited by 44

Coordinate activation of the corticotropic axis by insulin-induced hypoglycemia: simultaneous estimates of β-endorphin, adrenocorticotropin and cortisol secretion and disappearance in normal men

Iranmanesh, A., Lizarralde, G., & Veldhuis, J. D. (1993) · Acta Endocrinologica

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 43

Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men

Keenan, D. M., & Veldhuis, J. D. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 43

Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation

Keenan, D. M., & Veldhuis, J. D. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 41

Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness

Keenan, D. M., Roelfsema, F., Carroll, B. J., Iranmanesh, A., & Veldhuis, J. D. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 41

Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women

Sharma, A. N., Aoun, P., Wigham, J. R., Weist, S. M., & Veldhuis, J. D. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 39

Impact of Estradiol Supplementation on Dual Peptidyl Drive of GH Secretion in Postmenopausal Women

Veldhuis, J. D., Evans, W. S., & Bowers, C. Y. (2002) · The Journal of Clinical Endocrinology & Metabolism

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 36

Short-Term Aromatase-Enzyme Blockade Unmasks Impaired Feedback Adaptations in Luteinizing Hormone and Testosterone Secretion in Older Men

Veldhuis, J. D., & Iranmanesh, A. (2005) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesHypothalamic control of reproductive hormones

Cited by 36