Brown, Gordon D.

Hidden Killers: Human Fungal Infections

Brown, G. D., Denning, D. W., Gow, N. A. R., Levitz, S. M., Netea, M. G., & White, T. C. (2012) · Science Translational Medicine

Antifungal resistance and susceptibilityFungal Infections and Studies

Cited by 4,284

A new receptor for β-glucans

Brown, G. D., & Gordon, S. (2001) · Nature

Immune Response and InflammationImmune responses and vaccinations

Cited by 1,579

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

LeibundGut-Landmann, S., Groß, O., Robinson, M. J., Osorio, F., Slack, E. C., Tsoni, S. V., Schweighoffer, E., Tybulewicz, V., Brown, G. D., Ruland, J., et al. (2007) · Nature Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 1,191

Dectin-1: a signalling non-TLR pattern-recognition receptor

Brown, G. D. (2006) · Nature Reviews Immunology

Immune Response and InflammationImmune responses and vaccinations

Cited by 1,158

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

Iliev, I. D., Funari, V. A., Taylor, K. D., Nguyen, Q., Reyes, C. N., Strom, S. P., Brown, J., Becker, C. A., Fleshner, P. R., Dubinsky, M., et al. (2012) · Science

Gut microbiota and healthInflammatory Bowel Disease

Cited by 1,073

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

Branzk, N., Lubojemska, A., Hardison, S. E., Wang, Q., Gutierrez, M. G., Brown, G. D., & Papayannopoulos, V. (2014) · Nature Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsAntimicrobial Peptides and Activities

Cited by 1,037

An integrated model of the recognition of Candida albicans by the innate immune system

Netea, M. G., Brown, G. D., Kullberg, B. J., & Gow, N. A. R. (2008) · Nature Reviews Microbiology

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 946

Human dectin-1 deficiency and mucocutaneous fungal infections

Ferwerda, B., Ferwerda, G., Plantinga, T. S., Willment, J. A., van Spriel, A. B., Venselaar, H., Elbers, C. C., Johnson, M. D., Cambi, A., Huysamen, C., et al. (2009) · New England Journal of Medicine

Immunodeficiency and Autoimmune DisordersAntifungal resistance and susceptibility

Cited by 752

The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus

Steele, C., Rapaka, R. R., Metz, A., Pop, S. M., Williams, D. L., Gordon, S., Kolls, J. K., & Brown, G. D. (2005) · PLoS Pathogens

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 509

C-type lectins in immunity: recent developments

Dambuza, I. M., & Brown, G. D. (2015) · Current Opinion in Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 482

TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

Wang, S., Sudan, R., Peng, V., Zhou, Y., Du, S., Yuede, C. M., Lei, T., Hou, J., Cai, Z., Cella, M., et al. (2022) · Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 471

C-type lectin receptors orchestrate antifungal immunity

Hardison, S. E., & Brown, G. D. (2012) · Nature Immunology

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 460

The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria

Gey van Pittius, N. C., Gamieldien, J., Hide, W., Brown, G. D., Siezen, R. J., & Beyers, A. D. (2001) · Genome Biology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 375

A neglected epidemic: Fungal infections in HIV/AIDS

Armstrong-James, D., Meintjes, G., & Brown, G. D. (2014) · Trends in Microbiology

Antifungal resistance and susceptibilityFungal Infections and Studies

Cited by 325

Immune Recognition of Candida albicans β‐glucan by Dectin‐1

Gow, N. A. R., Netea, M. G., Munro, C. A., Ferwerda, G., Bates, S., Mora‐Montes, H. M., Walker, L., Jansen, T., Jacobs, L., Tsoni, V., et al. (2007) · The Journal of Infectious Diseases

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 314

Lactate signalling regulates fungal β-glucan masking and immune evasion

Ballou, E. R., Avelar, G. M., Childers, D. S., Mackie, J., Bain, J. M., Wagener, J., Kastora, S. L., Panea, M. D., Hardison, S. E., Walker, L. A., et al. (2016) · Nature Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 269

Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

Brown, A. J. P., Brown, G. D., Netea, M. G., & Gow, N. A. R. (2014) · Trends in Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 258

Candida albicans morphology and dendritic cell subsets determine T helper cell differentiation

Kashem, S. W., Igyártó, B. Z., Gerami-Nejad, M., Kumamoto, Y., Mohammed, J., Jarrett, E., Drummond, R. A., Zurawski, S. M., Zurawski, G., Berman, J., et al. (2015) · Immunity

Antifungal resistance and susceptibilityT-cell and B-cell Immunology

Cited by 250

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with Increased Candida Colonization in Hematopoietic Stem Cell Transplant Recipients

Plantinga, T. S., van der Velden, W. J. F. M., Ferwerda, B., van Spriel, A. B., Adema, G., Feuth, T., Donnelly, J. P., Brown, G. D., Kullberg, B., Blijlevens, N. M. A., et al. (2009) · Clinical Infectious Diseases

Antifungal resistance and susceptibilityImmunodeficiency and Autoimmune Disorders

Cited by 247

Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

Martínez-López, M., Iborra, S., Conde-Garrosa, R., Mastrangelo, A., Danne, C., Mann, E. R., Reid, D. M., Gaboriau-Routhiau, V., Chaparro, M., Lorenzo, M. P., et al. (2019) · Immunity

Immune Response and InflammationGut microbiota and health

Cited by 228

The role of Syk/CARD9 coupled C-type lectins in antifungal immunity

Drummond, R. A., Saijo, S., Iwakura, Y., & Brown, G. D. (2011) · European Journal of Immunology

Immune Response and InflammationAntifungal resistance and susceptibility

Cited by 221

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

Stappers, M. H. T., Clark, A. E., Aimanianda, V., Bidula, S., Reid, D. M., Asamaphan, P., Hardison, S. E., Dambuza, I. M., Valsecchi, I., Kerscher, B., et al. (2018) · Nature

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 200

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

Dambuza, I. M., Drake, T., Chapuis, A., Zhou, X., Correia, J., Taylor-Smith, L., LeGrave, N., Rasmussen, T., Fisher, M. C., Bicanic, T., et al. (2018) · PLoS Pathogens

Fungal Infections and StudiesFungal and yeast genetics research

Cited by 182

Syk-coupled C-type lectins in immunity

Kerrigan, A. M., & Brown, G. D. (2011) · Trends in Immunology

Immune Response and InflammationImmune responses and vaccinations

Cited by 170