Jack, Clifford R.

Quantitative magnetic resonance techniques as surrogate markers of Alzheimer’s disease

Kantarci, K., & Jack, C. R. (2004) · NeuroRX

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Diffusion models reveal white matter microstructural changes with ageing, pathology and cognition

Raghavan, S., Reid, R. I., Przybelski, S. A., Lesnick, T. G., Graff-Radford, J., Schwarz, C. G., Knopman, D. S., Mielke, M. M., Machulda, M. M., Petersen, R. C., et al. (2021) · Brain Communications

Advanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment Research

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Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease

Young, C. B., Winer, J. R., Younes, K., Cody, K. A., Betthauser, T. J., Johnson, S. C., Schultz, A., Sperling, R. A., Greicius, M. D., Cobos, I., et al. (2022) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals

Wennberg, A. M., Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Murray, M. E., Machulda, M. M., Petrucelli, L., Mielke, M. M., Jack, C. R., Knopman, D. S., et al. (2019) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 79

Regional Distribution, Asymmetry, and Clinical Correlates of Tau Uptake on [ 18 F]AV-1451 PET in Atypical Alzheimer’s Disease

Tetzloff, K. A., Graff-Radford, J., Martin, P. R., Tosakulwong, N., Machulda, M. M., Duffy, J. R., Clark, H. M., Senjem, M. L., Schwarz, C. G., Spychalla, A. J., et al. (2018) · Journal of Alzheimer’s Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 78

A computational model of neurodegeneration in Alzheimer’s disease

Jones, D., Lowe, V., Graff-Radford, J., Botha, H., Barnard, L., Wiepert, D., Murphy, M. C., Murray, M., Senjem, M., Gunter, J., et al. (2022) · Nature Communications

Dementia and Cognitive Impairment ResearchFunctional Brain Connectivity Studies

Cited by 78

Assessing atrophy measurement techniques in dementia: results from the MIRIAD atrophy challenge

Cash, D. M., Frost, C., Iheme, L. O., Ünay, D., Kandemir, M., Fripp, J., Salvado, O., Bourgeat, P., Reuter, M., Fischl, B., et al. (2015) · NeuroImage

Dementia and Cognitive Impairment ResearchMedical Image Segmentation Techniques

Cited by 72

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Chen, S.-D., Lu, J.-Y., Li, H.-Q., Yang, Y.-X., Jiang, J.-H., Cui, M., Zuo, C.-T., Tan, L., Dong, Q., Yu, J.-T., et al. (2021) · Translational Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 71

Emerging β-amyloid pathology and accelerated cortical atrophy

Mattsson, N., Insel, P. S., Nosheny, R., Tosun, D., Trojanowski, J. Q., Shaw, L. M., Jack, C. R., Donohue, M. C., & Weiner, M. W. (2014) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 71

In vivo 18 F-AV-1451 tau PET signal in MAPT mutation carriers varies by expected tau isoforms

Jones, D. T., Knopman, D. S., Graff-Radford, J., Syrjanen, J. A., Senjem, M. L., Schwarz, C. G., Dheel, C., Wszolek, Z., Rademakers, R., Kantarci, K., et al. (2018) · Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 71

Sex differences in longitudinal tau-PET in preclinical Alzheimer disease: a meta-analysis

Coughlan, G. T., Klinger, H. M., Boyle, R., Betthauser, T. J., Binette, A. P., Christenson, L., Chadwick, T., Hansson, O., Harrison, T. M., Healy, B., et al. (2025) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 69

Selective Worsening of Brain Injury Biomarker Abnormalities in Cognitively Normal Elderly Persons With β-Amyloidosis

Knopman, D. S., Jack, C. R., Wiste, H. J., Weigand, S. D., Vemuri, P., Lowe, V. J., Kantarci, K., Gunter, J. L., Senjem, M. L., Mielke, M. M., et al. (2013) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 68

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology

Morris, J. C., Weiner, M., Xiong, C., Beckett, L., Coble, D., Saito, N., Aisen, P. S., Allegri, R., Benzinger, T. L. S., Berman, S. B., et al. (2022) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 68

Diffusion tensor imaging comparison of progressive supranuclear palsy and corticobasal syndromes

Whitwell, J. L., Schwarz, C. G., Reid, R. I., Kantarci, K., Jack, C. R., & Josephs, K. A. (2014) · Parkinsonism & Related Disorders

Parkinson's Disease Mechanisms and TreatmentsAdvanced Neuroimaging Techniques and Applications

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Alliance for aging research AD biomarkers work group: structural MRI

Jack, C. R. (2011) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment

Knopman, D. S., Lundt, E. S., Therneau, T. M., Albertson, S. M., Gunter, J. L., Senjem, M. L., Schwarz, C. G., Mielke, M. M., Machulda, M. M., Boeve, B. F., et al. (2021) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 61

White matter abnormalities and cognition in aging and Alzheimer disease

Peter, C., Sathe, A., Shashikumar, N., Pechman, K. R., Workmeister, A. W., Jackson, T. B., Huo, Y., Mukherjee, S., Mez, J., Dumitrescu, L. C., et al. (2025) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 59

Sensitivity–Specificity of Tau and Amyloid β Positron Emission Tomography in Frontotemporal Lobar Degeneration

Ghirelli, A., Tosakulwong, N., Weigand, S. D., Clark, H. M., Ali, F., Botha, H., Duffy, J. R., Utianski, R. L., Buciuc, M., Murray, M. E., et al. (2020) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 59

KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

Neitzel, J., Franzmeier, N., Rubinski, A., Dichgans, M., Brendel, M., (ADNI), A. D. N. I., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., et al. (2021) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Predicting functional decline in behavioural variant frontotemporal dementia

Josephs, K. A., Whitwell, J. L., Weigand, S. D., Senjem, M. L., Boeve, B. F., Knopman, D. S., Smith, G. E., Ivnik, R. J., Jack, C. R., & Petersen, R. C. (2011) · Brain

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

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Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease

Huang, M., Yang, W., Feng, Q., Chen, W., Initiative, T. A. D. N., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., et al. (2017) · Scientific Reports

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline

Mielke, M. M., Aakre, J. A., Algeciras‐Schimnich, A., Proctor, N. K., Machulda, M. M., Eichenlaub, U., Knopman, D. S., Vemuri, P., Graff‐Radford, J., Jack, C. R., et al. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 55

Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome

Tetzloff, K. A., Duffy, J. R., Clark, H. M., Utianski, R. L., Strand, E. A., Machulda, M. M., Botha, H., Martin, P. R., Schwarz, C. G., Senjem, M. L., et al. (2019) · Brain

Dementia and Cognitive Impairment ResearchNeurobiology of Language and Bilingualism

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Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., et al. (2023) · The Lancet Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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