Moncada, Salvador

Nitric oxide: physiology, pathophysiology, and pharmacology.

Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension Pharmacology

Cited by 15,525

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension Pharmacology

Cited by 10,704

The L-Arginine-Nitric Oxide Pathway

Epstein, F. H., Moncada, S., & Higgs, A. (1993) · New England Journal of Medicine

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension Pharmacology

Cited by 6,678

Nitric oxide synthases in mammals

Knowles, R. G., & Moncada, S. (1994) · Biochemical Journal

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 2,752

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

Leone, A., Moncada, S., Vallance, P., Calver, A., & Collier, J. (1992) · The Lancet

Nitric Oxide and Endothelin EffectsCancer-related gene regulation

Cited by 2,107

Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man

Vallance, P., Collier, J., & Moncada, S. (1989) · The Lancet

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 1,590

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · The Lancet

Nitric Oxide and Endothelin EffectsPlatelet Disorders and Treatments

Cited by 1,437

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide

Nisoli, E., Clementi, E., Paolucci, C., Cozzi, V., Tonello, C., Sciorati, C., Bracale, R., Valerio, A., Francolini, M., Moncada, S., et al. (2003) · Science

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 1,243

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: Implications for neurodegenerative diseases

Cleeter, M. W. J., Cooper, J. M., Darley-Usmar, V. M., Moncada, S., & Schapira, A. H. V. (1994) · FEBS Letters

Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects

Cited by 1,241

An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.

Radomski, M. W., Palmer, R. M., & Moncada, S. (1990) · Proceedings of the National Academy of Sciences

Platelet Disorders and TreatmentsNitric Oxide and Endothelin Effects

Cited by 1,208

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS

Nisoli, E., Tonello, C., Cardile, A., Cozzi, V., Bracale, R., Tedesco, L., Falcone, S., Valerio, A., Cantoni, O., Clementi, E., et al. (2005) · Science

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 1,107

Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans

Gustafsson, L. E., Leone, A. M., Persson, M. G., Wiklund, N. P., & Moncada, S. (1991) · Biochemical and Biophysical Research Communications

Nitric Oxide and Endothelin EffectsAdvanced Chemical Sensor Technologies

Cited by 964

The discovery of nitric oxide and its role in vascular biology

Moncada, S., & Higgs, E. A. (2006) · British Journal of Pharmacology

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 863

Persistent inhibition of cell respiration by nitric oxide: Crucial role of S -nitrosylation of mitochondrial complex I and protective action of glutathione

Clementi, E., Brown, G. C., Feelisch, M., & Moncada, S. (1998) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 863

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1

Herrero-Mendez, A., Almeida, A., Fernández, E., Maestre, C., Moncada, S., & Bolaños, J. P. (2009) · Nature Cell Biology

Ubiquitin and proteasome pathwaysMetabolism, Diabetes, and Cancer

Cited by 844

The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · Biochemical and Biophysical Research Communications

Platelet Disorders and TreatmentsNitric Oxide and Endothelin Effects

Cited by 746

Redistribution of Intracellular Oxygen in Hypoxia by Nitric Oxide: Effect on HIF1α

Hagen, T., Taylor, C. T., Lam, F., & Moncada, S. (2003) · Science

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 704

Nitric oxide synthase activity in human breast cancer

Thomsen, L., Miles, D., Happerfield, L., Bobrow, L., Knowles, R., & Moncada, S. (1995) · British Journal of Cancer

Nitric Oxide and Endothelin EffectsAngiogenesis and VEGF in Cancer

Cited by 626

Hyperdynamic circulation in cirrhosis: A role for nitric oxide?

Vallance, P., & Moncada, S. (1991) · The Lancet

Liver Disease and TransplantationNitric Oxide and Endothelin Effects

Cited by 615

Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals

Nisoli, E., Falcone, S., Tonello, C., Cozzi, V., Palomba, L., Fiorani, M., Pisconti, A., Brunelli, S., Cardile, A., Francolini, M., et al. (2004) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 495

Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia

Guarner, C., Soriano, G., Tomas, A., Bulbena, O., Novella, M. T., Balanzo, J., Vilardell, F., Mourelle, M., & Moncada, S. (1993) · Hepatology

Liver Disease and TransplantationNitric Oxide and Endothelin Effects

Cited by 489

Different Responses of Astrocytes and Neurons to Nitric Oxide: The Role of Glycolytically Generated ATP in Astrocyte Protection

Almeida, A., Almeida, J., Bolaños, J. P., & Moncada, S. (2001) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 423

Nitric Oxide and Mitochondrial Signaling: From Physiology to Pathophysiology

Erusalimsky, J. D., & Moncada, S. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology

Nitric Oxide and Endothelin EffectsMitochondrial Function and Pathology

Cited by 336

On the mechanism by which vascular endothelial cells regulate their oxygen consumption

Clementi, E., Brown, G. C., Foxwell, N., & Moncada, S. (1999) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsMitochondrial Function and Pathology

Cited by 296