Gruber, Stephan

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

Liu, H. W., Roisné-Hamelin, F., Beckert, B., Li, Y., Myasnikov, A., & Gruber, S. (2022) · Molecular Cell

Bacterial Genetics and BiotechnologyDNA Repair Mechanisms

Cited by 53

DNA-measuring Wadjet SMC ATPases restrict smaller circular plasmids by DNA cleavage

Liu, H. W., Roisné-Hamelin, F., Beckert, B., Myasnikov, A., Li, Y., & Gruber, S. (2022) · Molecular Cell

Bacterial Genetics and BiotechnologyDNA Repair Mechanisms

Cited by 53

SMC motor proteins extrude DNA asymmetrically and can switch directions

Barth, R., Davidson, I. F., van der Torre, J., Taschner, M., Gruber, S., Peters, J.-M., & Dekker, C. (2025) · Cell

Genomics and Chromatin DynamicsDNA Repair Mechanisms

Cited by 40

Structural basis for plasmid restriction by SMC JET nuclease

Roisné-Hamelin, F., Liu, H. W., Taschner, M., Li, Y., & Gruber, S. (2024) · Molecular Cell

Bacterial Genetics and BiotechnologyDNA Repair Mechanisms

Cited by 34

A joint-ParB interface promotes Smc DNA recruitment

Bock, F. P., Liu, H. W., Anchimiuk, A., Diebold-Durand, M.-L., & Gruber, S. (2022) · Cell Reports

Bacterial Genetics and BiotechnologyGenomics and Chromatin Dynamics

Cited by 28

Structure and activation mechanism of a Lamassu phage and plasmid defense system

Li, Y., Adams, D. W., Liu, H. W., Shaw, S. J., Uchikawa, E., Jaskólska, M., Stutzmann, S., Righi, L., Szczelkun, M. D., Blokesch, M., et al. (2025) · Nature Structural & Molecular Biology

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 14

Structure and Activation Mechanism of a Lamassu Phage Defence System

Li, Y., Adams, D. W., Liu, H. W., Shaw, S. J., Uchikawa, E., Jaskólska, M., Stutzmann, S., Righi, L., Szczelkun, M. D., Blokesch, M., et al. (2025) · Nature Structural & Molecular Biology

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 14

Structure of a Type II SMC Wadjet Complex from Neobacillus vireti

Roisné-Hamelin, F., Liu, H. W., & Gruber, S. (2025) · Structure

Bacterial Genetics and BiotechnologyCRISPR and Genetic Engineering

Cited by 4

Single-domain antibody inhibitors target the coiled coil arms of the Bacillus subtilis SMC complex

Gosselin, O. J., Taschner, M., Huber-Hürlimann, L. M., Seeger, M. A., & Gruber, S. (2026) · eLife

Bacterial Genetics and BiotechnologyBiochemical and Structural Characterization

Cited by 0