Akil, Huda

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, Stahl, E. A., BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., et al. (2019) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,519

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Psychiatric GWAS Consortium Bipolar Disorder Working Group, Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., et al. (2011) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,344

Pattern and time course of immediate early gene expression in rat brain following acute stress

Cullinan, W. E., Herman, J. P., Battaglia, D. F., Akil, H., & Watson, S. J. (1995) · Neuroscience

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 1,056

A selective role for dopamine in stimulus-reward learning

Flagel, S. B., Clark, J. J., Robinson, T. E., Mayo, L., Czuj, A., Willuhn, I., Akers, C. A., Clinton, S. M., Phillips, P. E. M., & Akil, H. (2011) · Nature

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 1,026

Rare coding variants in ten genes confer substantial risk for schizophrenia

Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 983

Revisiting the Stress Concept: Implications for Affective Disorders

McEwen, B. S., & Akil, H. (2020) · The Journal of Neuroscience

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 686

Circadian patterns of gene expression in the human brain and disruption in major depressive disorder

Li, J. Z., Bunney, B. G., Meng, F., Hagenauer, M. H., Walsh, D. M., Vawter, M. P., Evans, S. J., Choudary, P. V., Cartagena, P., Barchas, J. D., et al. (2013) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninTreatment of Major Depression

Cited by 589

Individual differences in the attribution of incentive salience to reward-related cues: implications for addiction

Flagel, S. B., Akil, H., & Robinson, T. E. (2009) · Neuropharmacology

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 561

Anatomy of an Endogenous Antagonist: Relationship between Agouti-Related Protein and Proopiomelanocortin in Brain

Bagnol, D., Lu, X.-Y., Kaelin, C. B., Day, H. E. W., Ollmann, M., Gantz, I., Akil, H., Barsh, G. S., & Watson, S. J. (1999) · The Journal of Neuroscience

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 425

Dysregulation of the fibroblast growth factor system in major depression

Evans, S. J., Choudary, P. V., Neal, C. R., Li, J. Z., Vawter, M. P., Tomita, H., Lopez, J. F., Thompson, R. C., Meng, F., Stead, J. D., et al. (2004) · Proceedings of the National Academy of Sciences

Treatment of Major DepressionFibroblast Growth Factor Research

Cited by 424

Neural circuits mediating stress

López, J. F., Akil, H., & Watson, S. J. (1999) · Biological Psychiatry

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 373

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

Bernard, R., Kerman, I. A., Thompson, R. C., Jones, E. G., Bunney, W. E., Barchas, J. D., Schatzberg, A. F., Myers, R. M., Akil, H., & Watson, S. J. (2011) · Molecular Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 372

Delayed effects of chronic variable stress during peripubertal‐juvenile period on hippocampal morphology and on cognitive and stress axis functions in rats

Isgor, C., Kabbaj, M., Akil, H., & Watson, S. J. (2004) · Hippocampus

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 341

An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction

Flagel, S. B., Robinson, T. E., Clark, J. J., Clinton, S. M., Watson, S. J., Seeman, P., Phillips, P. E. M., & Akil, H. (2010) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 339

Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain

Tomita, H., Vawter, M. P., Walsh, D. M., Evans, S. J., Choudary, P. V., Li, J., Overman, K. M., Atz, M. E., Myers, R. M., Jones, E. G., et al. (2004) · Biological Psychiatry

Molecular Biology Techniques and ApplicationsGene expression and cancer classification

Cited by 331

Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia

López-Figueroa, A. L., Norton, C. S., López-Figueroa, M. O., Armellini-Dodel, D., Burke, S., Akil, H., López, J. F., & Watson, S. J. (2004) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 296

Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions

Li, J. Z., Vawter, M. P., Walsh, D. M., Tomita, H., Evans, S. J., Choudary, P. V., Lopez, J. F., Avelar, A., Shokoohi, V., Chung, T., et al. (2004) · Human Molecular Genetics

Molecular Biology Techniques and ApplicationsCell death mechanisms and regulation

Cited by 261

Post-mortem molecular profiling of three psychiatric disorders

Ramaker, R. C., Bowling, K. M., Lasseigne, B. N., Hagenauer, M. H., Hardigan, A. A., Davis, N. S., Gertz, J., Cartagena, P. M., Walsh, D. M., Vawter, M. P., et al. (2017) · Genome Medicine

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 219

Selective Breeding for Divergence in Novelty-seeking Traits: Heritability and Enrichment in Spontaneous Anxiety-related Behaviors

Stead, J. D. H., Clinton, S., Neal, C., Schneider, J., Jama, A., Miller, S., Vazquez, D. M., Watson, S. J., & Akil, H. (2006) · Behavior Genetics

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 209

Mineralocorticoid Receptor Function in Major Depression

Young, E. A., Lopez, J. F., Murphy-Weinberg, V., Watson, S. J., & Akil, H. (2003) · Archives of General Psychiatry

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 204

The Fibroblast Growth Factor Family: Neuromodulation of Affective Behavior

Turner, C. A., Watson, S. J., & Akil, H. (2012) · Neuron

Fibroblast Growth Factor ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 160

Role of corticotropin-releasing hormone in the amygdala and bed nucleus of the stria terminalis in the behavioral, pain modulatory, and endocrine consequences of opiate withdrawal

McNally, G. P., & Akil, H. (2002) · Neuroscience

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 141

The Fibroblast Growth Factor System and Mood Disorders

Turner, C. A., Akil, H., Watson, S. J., & Evans, S. J. (2006) · Biological Psychiatry

Treatment of Major DepressionFibroblast Growth Factor Research

Cited by 131