Gandal, Michael J.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Demontis, D., Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., et al. (2019) · Nature Genetics

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 2,203

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Sharon, G., Cruz, N. J., Kang, D.-W., Gandal, M. J., Wang, B., Kim, Y.-M., Zink, E. M., Casey, C. P., Taylor, B. C., Lane, C. J., et al. (2019) · Cell

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 1,182

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Gandal, M. J., Haney, J. R., Parikshak, N. N., Leppa, V., Ramaswami, G., Hartl, C., Schork, A. J., Appadurai, V., Buil, A., Werge, T. M., et al. (2018) · Science

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,095

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

Li, M., Santpere, G., Imamura Kawasawa, Y., Evgrafov, O. V., Gulden, F. O., Pochareddy, S., Sunkin, S. M., Li, Z., Shin, Y., Zhu, Y., et al. (2018) · Science

Genetics and Neurodevelopmental DisordersGenomics and Chromatin Dynamics

Cited by 810

Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

Parikshak, N. N., Swarup, V., Belgard, T. G., Irimia, M., Ramaswami, G., Gandal, M. J., Hartl, C., Leppa, V., Ubieta, L. D. L. T., Huang, J., et al. (2016) · Nature

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 685

Chromosome conformation elucidates regulatory relationships in developing human brain

Won, H., de la Torre-Ubieta, L., Stein, J. L., Parikshak, N. N., Huang, J., Opland, C. K., Gandal, M. J., Sutton, G. J., Hormozdiari, F., Lu, D., et al. (2016) · Nature

Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities

Cited by 584

Inherited and de novo genetic risk for autism impacts shared networks

Ruzzo, E. K., Pérez-Cano, L., Jung, J.-Y., Wang, L.-K., Kashef-Haghighi, D., Hartl, C., Singh, C., Xu, J., Hoekstra, J. N., Leventhal, O., et al. (2019) · Cell

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 457

Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders

Parikshak, N. N., Gandal, M. J., & Geschwind, D. H. (2015) · Nature Reviews Genetics

Bioinformatics and Genomic NetworksGenetics and Neurodevelopmental Disorders

Cited by 430

Deletion of vanilloid receptor 1_expressing primary afferent neurons for pain control

Karai, L., Brown, D. C., Mannes, A. J., Connelly, S. T., Brown, J., Gandal, M., Wellisch, O. M., Neubert, J. K., Olah, Z., & Iadarola, M. J. (2004) · Journal of Clinical Investigation

Pain Mechanisms and TreatmentsIon Channels and Receptors

Cited by 340

Validating γ oscillations and delayed auditory responses as translational biomarkers of autism

Gandal, M. J., Edgar, J. C., Ehrlichman, R. S., Mehta, M., Roberts, T. P. L., & Siegel, S. J. (2010) · Biological Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 314

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

Zhang, M. J., Hou, K., Dey, K. K., Sakaue, S., Jagadeesh, K. A., Weinand, K., Taychameekiatchai, A., Rao, P., Pisco, A. O., Zou, J., et al. (2022) · Nature Genetics

Single-cell and spatial transcriptomicsGenetic Associations and Epidemiology

Cited by 302

Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia.

Gandal, M. J., Edgar, J. C., Klook, K., & Siegel, S. J. (2012) · Neuropharmacology

Schizophrenia research and treatmentNeural dynamics and brain function

Cited by 269

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability

Singh, T., Walters, J. T. R., Johnstone, M., Curtis, D., Suvisaari, J., Torniainen, M., Rees, E., Iyegbe, C., Blackwood, D., McIntosh, A. M., et al. (2017) · Nature Genetics

Schizophrenia research and treatmentGenomics and Rare Diseases

Cited by 231

The road to precision psychiatry: translating genetics into disease mechanisms

Gandal, M. J., Leppa, V., Won, H., Parikshak, N. N., & Geschwind, D. H. (2016) · Nature Neuroscience

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 223

GABAB-mediated rescue of altered excitatory–inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction

Gandal, M. J., Sisti, J., Klook, K., Ortinski, P. I., Leitman, V, Liang, Y., Thieu, T., Anderson, R., Pierce, R. C., Jonak, G., et al. (2012) · Translational Psychiatry

Neuroscience and Neuropharmacology ResearchSchizophrenia research and treatment

Cited by 204

Quantum computing at the frontiers of biological sciences

Emani, P. S., Warrell, J., Anticevic, A., Bekiranov, S., Gandal, M., McConnell, M. J., Sapiro, G., Aspuru-Guzik, A., Baker, J. T., Bastiani, M., et al. (2021) · Nature Methods

Quantum Computing Algorithms and ArchitectureDNA and Biological Computing

Cited by 163

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J., Murnyak, B., Wendt, F., Adams, M., et al. (2023) · American Journal of Psychiatry

Genetic Associations and EpidemiologySuicide and Self-Harm Studies

Cited by 160

Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

Ramaswami, G., Won, H., Gandal, M. J., Haney, J., Wang, J. C., Wong, C. C. Y., Sun, W., Prabhakar, S., Mill, J., & Geschwind, D. H. (2020) · Nature Communications

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 113

Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia

Carlson, G. C., Talbot, K., Halene, T. B., Gandal, M. J., Kazi, H. A., Schlosser, L., Phung, Q. H., Gur, R. E., Arnold, S. E., & Siegel, S. J. (2011) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 103

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Hu, B., Won, H., Mah, W., Park, R. B., Kassim, B., Spiess, K., Kozlenkov, A., Crowley, C. A., Pochareddy, S., The PsychENCODE Consortium, et al. (2021) · Nature Communications

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 103

In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia

Amann, L. C., Gandal, M. J., Lin, R., Liang, Y., & Siegel, S. J. (2010) · Pharmaceutical Research

Advanced Drug Delivery SystemsSchizophrenia research and treatment

Cited by 99

Measuring the Maturity of the Fast-Spiking Interneuron Transcriptional Program in Autism, Schizophrenia, and Bipolar Disorder

Gandal, M. J., Nesbitt, A. M., McCurdy, R. M., & Alter, M. D. (2012) · PLoS ONE

Schizophrenia research and treatmentAutism Spectrum Disorder Research

Cited by 67