Kwakkel, Joan

Beyond Low Plasma T3: Local Thyroid Hormone Metabolism during Inflammation and Infection

Boelen, A., Kwakkel, J., & Fliers, E. (2011) · Endocrine Reviews

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 287

Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice

Boelen, A., Kwakkel, J., Thijssen-Timmer, D., Alkemade, A., Fliers, E., & Wiersinga, W. (2004) · Journal of Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 159

Induction of Type 3 Deiodinase Activity in Inflammatory Cells of Mice with Chronic Local Inflammation

Boelen, A., Kwakkel, J., Alkemade, A., Renckens, R., Kaptein, E., Kuiper, G., Wiersinga, W. M., & Visser, T. J. (2005) · Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 117

A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages

Kwakkel, J., Surovtseva, O. V., de Vries, E. M., Stap, J., Fliers, E., & Boelen, A. (2014) · Endocrinology

Thyroid Disorders and TreatmentsImmune Response and Inflammation

Cited by 88

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging

Visser, W. E., Bombardieri, C. R., Zevenbergen, C., Barnhoorn, S., Ottaviani, A., van der Pluijm, I., Brandt, R., Kaptein, E., van Heerebeek, R., van Toor, H., et al. (2016) · PLOS ONE

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

Cited by 82

Type 3 Deiodinase Is Highly Expressed in Infiltrating Neutrophilic Granulocytes in Response to Acute Bacterial Infection

Boelen, A., Boorsma, J., Kwakkel, J., Wieland, C. W., Renckens, R., Visser, T. J., Fliers, E., & Wiersinga, W. M. (2008) · Thyroid

Thyroid Disorders and TreatmentsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 70

Chronic local inflammation in mice results in decreased TRH and type 3 deiodinase mRNA expression in the hypothalamic paraventricular nucleus independently of diminished food intake

Boelen, A., Kwakkel, J., Wiersinga, W. M., & Fliers, E. (2006) · Journal of Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 64

Impaired Bacterial Clearance in Type 3 Deiodinase-Deficient Mice Infected with Streptococcus pneumoniae

Boelen, A., Kwakkel, J., Wieland, C. W., St. Germain, D. L., Fliers, E., & Hernandez, A. (2009) · Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 63

Differential involvement of nuclear factor-κB and activator protein-1 pathways in the interleukin-1β-mediated decrease of deiodinase type 1 and thyroid hormone receptor β1 mRNA

Kwakkel, J., Wiersinga, W. M., & Boelen, A. (2006) · Journal of Endocrinology

Thyroid Disorders and TreatmentsNF-κB Signaling Pathways

Cited by 56

Skeletal muscle deiodinase type 2 regulation during illness in mice

Kwakkel, J., van Beeren, H. C., Ackermans, M. T., Platvoet-ter Schiphorst, M. C., Fliers, E., Wiersinga, W. M., & Boelen, A. (2009) · Journal of Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 48

Tissue thyroid hormone metabolism is differentially regulated during illness in mice

Boelen, A., van der Spek, A. H., Bloise, F., de Vries, E. M., Surovtseva, O. V., van Beeren, M., Ackermans, M. T., Kwakkel, J., & Fliers, E. (2017) · Journal of Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 35

Leptin Administration Restores the Fasting-Induced Increase of Hepatic Type 3 Deiodinase Expression in Mice

Boelen, A., van Beeren, M., Vos, X., Surovtseva, O., Belegri, E., Saaltink, D.-J., Vreugdenhil, E., Kalsbeek, A., Kwakkel, J., & Fliers, E. (2012) · Thyroid

Thyroid Disorders and TreatmentsRegulation of Appetite and Obesity

Cited by 35

Interleukin-1β modulates endogenous thyroid hormone receptor α gene transcription in liver cells

Kwakkel, J., Wiersinga, W. M., & Boelen, A. (2007) · Journal of Endocrinology

Thyroid Disorders and TreatmentsNF-κB Signaling Pathways

Cited by 34

Thyroid Hormone Receptor α Modulates Lipopolysaccharide-Induced Changes in Peripheral Thyroid Hormone Metabolism

Kwakkel, J., Chassande, O., van Beeren, H. C., Fliers, E., Wiersinga, W. M., & Boelen, A. (2010) · Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 34

NFκB Signaling Is Essential for the Lipopolysaccharide-Induced Increase of Type 2 Deiodinase in Tanycytes

de Vries, E. M., Kwakkel, J., Eggels, L., Kalsbeek, A., Barrett, P., Fliers, E., & Boelen, A. (2014) · Endocrinology

NF-κB Signaling PathwaysNeuropeptides and Animal Physiology

Cited by 32

Thyroid Hormone Receptor β Mediates Acute Illness‐Induced Alterations in Central Thyroid Hormone Metabolism

Boelen, A., Kwakkel, J., Chassande, O., & Fliers, E. (2009) · Journal of Neuroendocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 32

Downregulation of Type 3 Deiodinase in the Hypothalamus During Inflammation

de Vries, E. M., Surovtseva, O., Vos, W. G., Kunst, R. F., van Beeren, M., Kwakkel, J., Chassande, O., Ackermans, M. T., Fliers, E., & Boelen, A. (2019) · Thyroid®

Thyroid Disorders and TreatmentsNeuropeptides and Animal Physiology

Cited by 16